Research graph
References from Preeclampsia and the anti-angiogenic state. Local targets link to admitted publications; unresolved targets remain external evidence.
Strategies to prevent and treat preeclampsia: evidence from randomized controlled trials
10.1016/j.semnephrol.2004.07.009 · 2004 · External reference
Preeclampsia: the role of angiogenic factors in its pathogenesis
10.1152/physiol.00043.2008 · 2009 · External reference
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
10.1172/jci17189 · 2003 · External reference
Angiogenic imbalance in the pathophysiology of preeclampsia: newer insights
10.1016/j.semnephrol.2004.07.003 · 2004 · External reference
Angiogenesis and vasculogenesis in pregnancy
10.1016/s0301-2115(03)00168-4 · 2003 · External reference
The role of vascular endothelial growth factor in angiogenesis
10.1159/000046610 · 2001 · External reference
Overexpression of the soluble vascular endothelial growth factor receptor in preeclamptic patients: pathophysiological consequences
10.1210/jc.2003-030528 · 2003 · External reference
Structure and function of VEGF/VEGF-receptor system involved in angiogenesis
10.1247/csf.26.25 · 2001 · External reference
VEGF and TGF-beta are required for the maintenance of the choroid plexus and ependyma
10.1084/jem.20072041 · 2008 · External reference
The biology of vascular endothelial growth factor
10.1210/edrv.18.1.0287 · 1997 · External reference
Expression and function of placenta growth factor: implications for abnormal placentation
10.1016/s1071-5576(03)00048-0 · 2003 · External reference
Colocalization of vascular endothelial growth factor (vascular permeability factor) and insulin in pancreatic islet cells
1995 · External reference
Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
10.1038/87904 · 2001 · External reference
Angiogenic factors and preeclampsia
10.1016/s0049-3848(09)70020-9 · 2009 · External reference
Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion?
10.1172/jci119387 · 1997 · External reference
Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome?
10.1172/jci119388 · 1997 · External reference
Preeclampsia and angiogenic imbalance
10.1146/annurev.med.59.110106.214058 · 2008 · External reference
Soluble endoglin and other circulating antiangiogenic factors in preeclampsia
10.1056/nejmoa055352 · 2006 · External reference
Circulating angiogenic factors and the risk of preeclampsia
10.1056/nejmoa031884 · 2004 · External reference
Soluble endoglin contributes to the pathogenesis of preeclampsia
10.1038/nm1429 · 2006 · External reference
Maternal serum sFlt1 concentration is an early and reliable predictive marker of preeclampsia
10.1373/clinchem.2004.036715 · 2004 · External reference
Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsia
10.1080/14767050400028816 · 2005 · External reference
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
10.1073/pnas.90.22.10705 · 1993 · External reference
Elevated placental soluble vascular endothelial growth factor receptor-1 inhibits angiogenesis in preeclampsia
10.1161/01.res.0000147365.86159.f5 · 2004 · External reference
Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria
10.1074/jbc.c300012200 · 2003 · External reference
Angiogenic dysfunction in molar pregnancy
10.1016/j.ajog.2009.09.005 · 2010 · External reference
Elevated serum soluble fms-like tyrosine kinase 1 (sFlt1) level in women with hydatidiform mole
2009 · External reference
Twin pregnancy and the risk of preeclampsia: bigger placenta or relative ischemia?
10.1016/j.ajog.2007.10.783 · 2008 · External reference
VEGF inhibition and renal thrombotic microangiopathy
10.1056/nejmoa0707330 · 2008 · External reference
A preeclampsia-like syndrome characterized by reversible hypertension and proteinuria induced by the multitargeted kinase inhibitors sunitinib and sorafenib
10.1093/jnci/djm311 · 2008 · External reference
Mechanisms of adverse effects of anti-VEGF therapy for cancer
10.1038/sj.bjc.6603813 · 2007 · External reference
A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia
10.1161/circresaha.108.171504 · 2008 · External reference
A recently evolved novel trophoblast-enriched secreted form of fms-like tyrosine kinase-1 variant is up-regulated in hypoxia and preeclampsia
10.1210/jc.2009-0017 · 2009 · External reference
Soluble endoglin contributes to the pathogenesis of preeclampsia
10.1038/nm1429 · 2006 · External reference
Animal models of preeclampsia
10.1016/j.semnephrol.2004.07.011 · 2004 · External reference
Nitric oxide formation is inversely related to serum levels of antiangiogenic factors soluble fms-like tyrosine kinase-1 and soluble endogline in preeclampsia
10.1161/hypertensionaha.108.115006 · 2008 · External reference
A sister’s risk: family history as a predictor of preeclampsia
10.1016/j.ajog.2005.06.034 · 2005 · External reference
Preeclampsia and risk of developing subsequent diabetes
10.3109/10641950802629675 · 2009 · External reference
Allelic variations in angiogenic pathway genes are associated with preeclampsia
10.1016/j.ajog.2010.01.040 · 2010 · External reference
Vascular endothelial growth factor gene polymorphisms and pre-eclampsia
10.1093/molehr/gah048 · 2004 · External reference
VEGF mRNA is unaltered in decidual and placental tissues in preeclampsia at delivery
10.1034/j.1600-0412.2001.080002093.x · 2001 · External reference
Genetic polymorphisms of vascular endothelial growth factor in severe pre-eclampsia
10.1093/molehr/gal024 · 2006 · External reference
Mapping the theories of preeclampsia and the role of angiogenic factors: a systematic review
10.1097/01.aog.0000249609.04831.7c · 2007 · External reference
Genes and the preeclampsia syndrome
10.1515/jpm.2008.004 · 2008 · External reference
Pre-eclampsia and trisomy 13
10.1111/j.1471-0528.1992.tb14436.x · 1992 · External reference
Fetal and maternal contributions to risk of pre-eclampsia: population based study
10.1136/bmj.316.7141.1343 · 1998 · External reference
Paternal and maternal components of the predisposition to preeclampsia
10.1056/nejm200103223441201 · 2001 · External reference
Genetic conflicts of pregnancy and childhood
1999 · External reference
Preeclampsia: recent insights
10.1161/01.hyp.0000188408.49896.c5 · 2005 · External reference
Combinations of maternal KIR and fetal HLA-C genes influence the risk of preeclampsia and reproductive success
10.1084/jem.20041214 · 2004 · External reference
Maternal segregation of the Dutch preeclampsia locus at 10q22 with a new member of the winged helix gene family
10.1038/ng1541 · 2005 · External reference
Evaluation of a new and automated electrochemiluminescence immunoassay for plasma sFlt-1 and PlGF levels in women with preeclampsia
10.1038/hr.2010.15 · 2010 · External reference
Automated assays for sVEGF R1 and PlGF as an aid in the diagnosis of preterm preeclampsia: a prospective clinical study
10.1016/j.ajog.2009.07.025 · 2010 · External reference
A prospective cohort study of the value of maternal plasma concentrations of angiogenic and anti-angiogenic factors in early pregnancy and midtrimester in the identification of patients destined to develop preeclampsia
10.3109/14767050902994754 · 2009 · External reference
10.1080/14767050701830480
10.1080/14767050701830480 · 2008 · External reference
Recombinant vascular endothelial growth factor 121 infusion lowers blood pressure and improves renal function in rats with placentalischemia-induced hypertension
10.1161/hypertensionaha.109.141937 · 2010 · External reference
Recombinant vascular endothelial growth factor 121 attenuates hypertension and improves kidney damage in a rat model of preeclampsia
10.1161/hypertensionaha.107.092098 · 2007 · External reference
Placental ischemia and soluble fms-like tyrosine kinase 1: cause or consequence of preeclampsia?
10.1038/sj.ki.5002281 · 2007 · External reference
