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References from The role of obesity in preeclampsia. Local targets link to admitted publications; unresolved targets remain external evidence.
Obesity and the metabolic syndrome in developing countries
10.1210/jc.2008-1595 · 2008 · External reference
Will all Americans become overweight or obese? Estimating the progression and cost of the US obesity epidemic
10.1038/oby.2008.351 · 2008 · External reference
The risk of preeclampsia rises with increasing prepregnancy body mass index
10.1016/j.annepidem.2004.12.008 · 2005 · External reference
Preeclampsia: recent insights
10.1161/01.hyp.0000188408.49896.c5 · 2005 · External reference
Long-term mortality after preeclampsia
10.1097/01.ede.0000152912.02042.cd · 2005 · External reference
Long term mortality of mothers and fathers after pre-eclampsia: population based cohort study
10.1136/bmj.323.7323.1213 · 2001 · External reference
Prepregnancy body mass index and the occurrence of severe hypertensive disorders of pregnancy
10.1097/01.ede.0000254119.99660.e7 · 2007 · External reference
Risk of early or severe pre-eclampsia related to pre-existing conditions
10.1093/ije/dyl271 · 2007 · External reference
Risk factors for pre-eclampsia among Zimbabwean women – maternal arm circumference and other anthropometric measures of obesity
10.1046/j.1365-3016.1998.00116.x · 1998 · External reference
Obesity and diabetes in the developing world—a growing challenge
10.1056/nejmp068177 · 2007 · External reference
Prepregnancy weight status and the risk of adverse pregnancy outcome
10.1080/00016340802303349 · 2008 · External reference
The surgical management of obesity in young women: consideration of the mother’s and baby’s health before, during, and after pregnancy
10.1007/s00464-008-0019-5 · 2008 · External reference
Pregnancy outcomes after bariatric surgery: maternal, fetal, and infant implications
10.1016/j.soard.2007.08.018 · 2008 · External reference
Determination of maternal body composition in pregnancy and its relevance to perinatal outcomes
10.1097/01.ogx.0000140039.10861.91 · 2004 · External reference
Total body water in pregnancy: assessment by using bioelectrical impedance
10.1093/ajcn/59.3.578 · 1994 · External reference
New equations for estimating body fat mass in pregnancy from body density or total body water
10.1093/ajcn/48.1.24 · 1988 · External reference
Relation of abdominal height to cardiovascular risk factors in young adults: the Bogalusa heart study
10.1093/oxfordjournals.aje.a010292 · 2000 · External reference
Comparison of the release of adipokines by adipose tissue, adipose tissue matrix, and adipocytes from visceral and subcutaneous abdominal adipose tissues of obese humans
10.1210/en.2003-1336 · 2004 · External reference
Leptin plasma concentrations are dependent on body fat distribution in obese patients
10.1038/sj.ijo.0801385 · 2000 · External reference
Adipose tissue, inflammation, and cardiovascular disease
10.1161/01.res.0000163635.62927.34 · 2005 · External reference
Unresolved reference
2009 · External reference
Prepregnancy body mass index, gestational weight gain, and risk of hypertensive pregnancy among Latina women
10.1016/j.ajog.2008.08.021 · 2009 · External reference
Adipocytokines in normal and complicated pregnancies
10.1177/1933719109336614 · 2009 · External reference
Obesity and the role of adipose tissue in inflammation and metabolism
10.1093/ajcn/83.2.461s · 2006 · External reference
Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease
10.1210/jc.2006-0594 · 2006 · External reference
Insulin resistance syndrome in preeclampsia
10.1055/s-2007-1016251 · 1998 · External reference
Leptin during and after preeclamptic or normal pregnancy: its relation to serum insulin and insulin sensitivity
10.1016/s0026-0495(00)91559-2 · 2000 · External reference
Early experimental obesity is associated with coronary endothelial dysfunction and oxidative stress
2007 · External reference
Metabolic syndrome: a comprehensive perspective based on interactions between obesity, diabetes, and inflammation
10.1161/01.cir.0000158483.13093.9d · 2005 · External reference
Early occurrence of metabolic syndrome after hypertension in pregnancy
10.1097/01.aog.0000163252.02227.f8 · 2005 · External reference
Human obesity: from lipid abnormalities to lipid oxidation
1995 · External reference
Molecular mechanisms of insulin resistance
10.1111/j.1464-5491.2005.01566.x · 2005 · External reference
Role of oxidized low density lipoprotein in atherogenesis
10.1016/0163-7827(92)90006-5 · 1992 · External reference
Obesity and preeclampsia: the potential role of inflammation
10.1016/s0029-7844(01)01551-4 · 2001 · External reference
Inflammation and triglycerides partially mediate the effect of prepregnancy body mass index on the risk of preeclampsia
10.1093/aje/kwi334 · 2005 · External reference
Autocrine inhibition of leptin production by tumor necrosis factor-alpha (TNF-alpha) through TNF-alpha type-I receptor in vitro
10.1006/bbrc.1998.8199 · 1998 · External reference
Placental cytokines and the pathogenesis of preeclampsia
10.1111/j.1600-0897.1997.tb00222.x · 1997 · External reference
Tumor necrosis factor-a is elevated in plasma and amniotic fluid of patients with severe preeclampsia
10.1016/s0002-9378(94)70351-5 · 1994 · External reference
Expression of inflammatory cytokines in placentas from women with preeclampsia
2001 · External reference
A comparison of circulating TNF-alpha in obese and lean women with and without preeclampsia
10.1080/10641950701825838 · 2008 · External reference
Longitudinal assessment of maternal endothelial function and markers of inflammation and placental function throughout pregnancy in lean and obese mothers
10.1210/jc.2006-2083 · 2007 · External reference
Inflammatory status and insulin resistance
10.1097/00075197-200209000-00015 · 2002 · External reference
Circulating levels of immunoreactive cytokines in women with preeclampsia
10.1111/j.1600-0897.1998.tb00398.x · 1998 · External reference
Clustering of metabolic abnormalities in obese individuals: the role of genetic factors
10.3109/07853890109002062 · 2001 · External reference
Serum concentrations of retinol, alpha-tocopherol and the carotenoids are influenced by diet, race and obesity in a sample of healthy adolescents
10.1093/jn/131.8.2184 · 2001 · External reference
Serum concentrations of beta-carotene and alpha-tocopherol are associated with diet, smoking, and general and central adiposity
10.1093/ajcn/73.4.777 · 2001 · External reference
High intake of energy, sucrose, and polyunsaturated fatty acids is associated with increased risk of preeclampsia
10.1067/mob.2001.116687 · 2001 · External reference
The metabolic syndrome and adipocytokines
10.1016/j.febslet.2006.04.028 · 2006 · External reference
Leptin is a metabolic signal to the reproductive system
10.1210/endo.137.7.8770941 · 1996 · External reference
Leptin and atherosclerosis
10.1016/j.atherosclerosis.2006.03.003 · 2006 · External reference
Elevated leptin levels in subjects with familial combined hyperlipidemia are associated with the increased risk for CVD
10.1016/j.atherosclerosis.2005.03.019 · 2005 · External reference
Leptin in pregnancy
10.1095/biolreprod63.5.1219 · 2000 · External reference
Leptin, obesity and cardiovascular disease
10.1097/00041552-200403000-00010 · 2004 · External reference
Relationships between maternal plasma leptin, placental leptin mRNA and protein in normal pregnancy, pre-eclampsia and intrauterine growth restriction without pre-eclampsia
10.1093/molehr/gal064 · 2006 · External reference
Leptin messenger ribonucleic acid (mRNA) content in the human placenta at term: relationship to levels of leptin in cord blood and placental weight
10.1080/gye.17.4.311.316 · 2003 · External reference
Augmented placental production of leptin in preeclampsia: possible involvement of placental hypoxia
1998 · External reference
Maternal plasma leptin is increased in preeclampsia and positively correlates with fetal cord concentration
10.1016/s0002-9378(99)70280-2 · 1999 · External reference
Serum leptin levels and the severity of preeclampsia
10.1007/s004040000081 · 2000 · External reference
Free leptin is increased in normal pregnancy and further increased in preeclampsia
10.1053/meta.2000.7707 · 2000 · External reference
A longitudinal study of biochemical variables in women at risk of preeclampsia
10.1067/mob.2002.122969 · 2002 · External reference
Increased plasma levels of adipokines in preeclampsia: relationship to placenta and adipose tissue gene expression
2006 · External reference
Adiponectin concentrations in maternal serum: elevated in preeclampsia but unrelated to insulin sensitivity
10.1016/j.jsgi.2005.04.006 · 2005 · External reference
Serum adiponectin, leptin and soluble leptin receptor in pre-eclampsia
10.1016/j.ijgo.2006.06.015 · 2006 · External reference
Paradoxical elevation in adiponectin concentrations in women with preeclampsia
10.1161/01.hyp.0000095981.92542.f6 · 2003 · External reference
Maternal serum adiponectin multimers in preeclampsia
10.1515/jpm.2009.085 · 2009 · External reference
Serum levels of the adipokine visfatin are increased in pre-eclampsia
10.1111/j.1365-2265.2007.03147.x · 2008 · External reference
Selective increase in high molecular weight adiponectin concentration in serum of women with preeclampsia
10.1016/j.jri.2006.05.004 · 2007 · External reference
Serum sFlt1 concentration during preeclampsia and mid trimester blood pressure in healthy nulliparous women
10.1016/j.ajog.2005.10.192 · 2006 · External reference
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia
10.1172/jci17189 · 2003 · External reference
Elevated serum vascular endothelial growth factor is associated with visceral fat accumulation in human obese subjects
10.1007/s00125-003-1221-6 · 2003 · External reference
10.1016/s2210-7789(10)60127-4
10.1016/s2210-7789(10)60127-4 · External reference
We are what we eat: women and diet for cardiovascular health
10.1097/00005082-200511000-00014 · 2005 · External reference
Nutrient involvement in preeclampsia
10.1093/jn/133.5.1684s · 2003 · External reference
Vitamin C and the risk of preeclampsia—results from dietary questionnaire and plasma assay
10.1097/00001648-200207000-00008 · 2002 · External reference
Vitamin C and vitamin E in pregnant women at risk for pre-eclampsia (VIP trial): randomised placebo-controlled trial
10.1016/s0140-6736(06)68433-x · 2006 · External reference
Effect of antioxidants on the occurrence of pre-eclampsia in women at increased risk: a randomised trial
10.1016/s0140-6736(99)80010-5 · 1999 · External reference
Vitamins C and E and the risks of preeclampsia and perinatal complications
10.1056/nejmoa054186 · 2006 · External reference
Effect of folic acid treatment on endothelium-dependent vasodilation and nitric oxide-derived end products in hyperhomocysteinemic subjects
10.1016/s0002-9343(01)00696-9 · 2001 · External reference
Folic acid improves endothelial function in coronary artery disease via mechanisms largely independent of homocysteine lowering
10.1161/hc0102.101388 · 2002 · External reference
Effect of folic acid and antioxidant vitamins on endothelial dysfunction in patients with coronary artery disease
10.1016/s0735-1097(00)00809-3 · 2000 · External reference
Impaired NO-dependent vasodilation in patients with Type II (non-insulin-dependent) diabetes mellitus is restored by acute administration of folate
10.1007/s00125-002-0862-1 · 2002 · External reference
Folic acid reverts dysfunction of endothelial nitric oxide synthase
10.1161/01.res.86.11.1129 · 2000 · External reference
Influence of folic acid on postprandial endothelial dysfunction
10.1161/01.atv.20.1.185 · 2000 · External reference
Omega-3 fatty acids in maternal erythrocytes and risk of preeclampsia
10.1097/00001648-199505000-00007 · 1995 · External reference
Risk of preeclampsia in relation to elaidic acid (trans-fatty acid) in maternal erythrocytes
10.1159/000010007 · 1998 · External reference
Dyslipidemia in early second trimester is mainly a feature of women with early onset pre-eclampsia
2001 · External reference
Marine n-3 fatty acid and calcium intake in relation to pregnancy induced hypertension, intrauterine growth retardation, and preterm delivery. A case-control study
10.3109/00016349709047782 · 1997 · External reference
Blood pressure during pregnancy in Canadian Inuit: community differences related to diet
1991 · External reference
Consumption of high-fructose corn syrup in beverages may play a role in the epidemic of obesity
10.1093/ajcn/79.4.537 · 2004 · External reference
Fructose, weight gain, and the insulin resistance syndrome
10.1093/ajcn/76.5.911 · 2002 · External reference
A causal role for uric acid in fructose-induced metabolic syndrome
2006 · External reference
Epidemiologic data linking diet to hyperlipidemia and arteriosclerosis and thrombosis
10.1055/s-2008-1040404 · 1992 · External reference
Plasma ascorbic acid concentrations and fat distribution in 19,068 British men and women in the European Prospective Investigation into Cancer and Nutrition Norfolk cohort study
10.1093/ajcn/82.6.1203 · 2005 · External reference
Longitudinal associations between body mass index and serum carotenoids: the CARDIA study
10.1079/bjn20051638 · 2006 · External reference
Work, leisure-time physical activity, and risk of preeclampsia and gestational hypertension
10.1093/aje/kwh277 · 2004 · External reference
The effect of leisure time physical activity on the risk of pre-eclampsia and gestational hypertension
10.1136/jech.43.2.147 · 1989 · External reference
History of abortion and subsequent risk of preeclampsia
2003 · External reference
Recreational physical activity during pregnancy and risk of preeclampsia
10.1161/01.hyp.0000072270.82815.91 · 2003 · External reference
Sleep-disordered breathing and cardiovascular health
10.1097/01.mcp.0000183058.52924.70 · 2005 · External reference
A prospective study of sleep duration and coronary heart disease in women
10.1001/archinte.163.2.205 · 2003 · External reference
Pathogenesis of obstructive and central sleep apnea
10.1164/rccm.200412-1631so · 2005 · External reference
Serum leptin and vascular risk factors in obstructive sleep apnea
10.1378/chest.118.3.580 · 2000 · External reference
Advances in sleep-disordered breathing
10.1164/rccm.200509-1478oe · 2006 · External reference
HIF-1-dependent respiratory, cardiovascular, and redox responses to chronic intermittent hypoxia
10.1089/ars.2007.1691 · 2007 · External reference
Circulating cardiovascular risk factors in obstructive sleep apnoea: data from randomised controlled trials
10.1136/thx.2003.018739 · 2004 · External reference
Disorders of glucose metabolism in sleep apnea
10.1152/japplphysiol.00695.2005 · 2005 · External reference
Effects of sleep deprivation and exercise on glucose tolerance
1993 · External reference
Sleep-disordered breathing, glucose intolerance, and insulin resistance: the Sleep Heart Health Study
10.1093/aje/kwh261 · 2004 · External reference
Excess weight and sleep-disordered breathing
10.1152/japplphysiol.00587.2005 · 2005 · External reference
Sleep study in patients with overweight and obesity
2005 · External reference
Body fat distribution, serum leptin, and cardiovascular risk factors in men with obstructive sleep apnea
10.1378/chest.122.3.829 · 2002 · External reference
Leptin, obesity, and obstructive sleep apnea
10.1378/chest.118.3.569 · 2000 · External reference
Sleep loss and the risk for obesity and metabolic syndrome
2006 · External reference
Sleep apnea is a manifestation of the metabolic syndrome
10.1016/j.smrv.2005.01.006 · 2005 · External reference
Sleep and sleep disorders in pregnancy
10.7326/0003-4819-134-5-200103060-00012 · 2001 · External reference
Sleep disorders in pregnancy
10.1097/00063198-200311000-00005 · 2003 · External reference
Sleep complaints: snoring and daytime sleepiness in pregnant and pre-eclamptic women
10.1016/j.sleep.2004.12.007 · 2005 · External reference
The upper airway in pregnancy and pre-eclampsia
10.1164/rccm.200206-590oc · 2003 · External reference
Inspiratory flow limitation during sleep in pre-eclampsia: comparison with normal pregnant and nonpregnant women
10.1183/09031936.01.00053501 · 2001 · External reference
Snoring, pregnancy-induced hypertension, and growth retardation of the fetus
10.1378/chest.117.1.137 · 2000 · External reference
Biological significance of endogenous methylarginines that inhibit nitric oxide synthases
10.1016/s0008-6363(99)00162-5 · 1999 · External reference
Elevation of an endogenous inhibitor of nitric oxide synthesis in experimental congestive heart failure
10.1016/s0008-6363(97)00242-3 · 1998 · External reference
Asymmetric dimethylarginine (ADMA): a potential link between endothelial dysfunction and cardiovascular diseases in insulin resistance syndrome?
10.1007/s00125-002-0975-6 · 2002 · External reference
l-Arginine and hypertension
10.1093/jn/134.10.2807s · 2004 · External reference
Old and new cardiovascular risk factors: from unresolved issues to new opportunities
10.1016/s1567-5688(03)00028-x · 2003 · External reference
Weight loss reduces circulating asymmetrical dimethylarginine concentrations in morbidly obese women
10.1210/jc.2004-0672 · 2004 · External reference
Plasma concentration of asymmetric dimethylarginine, an endogenous inhibitor of nitric oxide synthase, is elevated in monkeys with hyperhomocyst(e)inemia or hypercholesterolemia
10.1161/01.atv.20.6.1557 · 2000 · External reference
Dietary composition as a determinant of plasma asymmetric dimethylarginine in subjects with mild hypercholesterolemia
10.1016/j.metabol.2003.12.028 · 2004 · External reference
Insulin resistance, ADMA levels, and cardiovascular disease
10.1001/jama.287.11.1451 · 2002 · External reference
Relationship between insulin resistance and an endogenous nitric oxide synthase inhibitor
10.1001/jama.287.11.1420 · 2002 · External reference
Elevated levels of plasma homocyst(e)ine and asymmetric dimethylarginine in elderly patients with stroke
10.1016/s0021-9150(01)00444-0 · 2001 · External reference
Amelioration of vascular endothelial dysfunction in obstructive sleep apnea syndrome by nasal continuous positive airway pressure—possible involvement of nitric oxide and asymmetric NG, NG-dimethylarginine
10.1253/circj.69.221 · 2005 · External reference
Relationship between obesity, smoking, and the endogenous nitric oxide synthase inhibitor, asymmetric dimethylarginine
10.1016/j.metabol.2004.06.026 · 2004 · External reference
Plasma asymmetric dimethylarginine concentrations are elevated in obese insulin-resistant women and fall with weight loss
10.1210/jc.2005-1441 · 2006 · External reference
Elevations of plasma methylarginines in obesity and ageing are related to insulin sensitivity and rates of protein turnover
10.1007/s00125-005-0066-6 · 2006 · External reference
Asymmetric dimethylarginine causes hypertension and cardiac dysfunction in humans and is actively metabolized by dimethylarginine dimethylaminohydrolase
10.1161/01.atv.0000081742.92006.59 · 2003 · External reference
The emerging role of asymmetric dimethylarginine as a novel cardiovascular risk factor
10.1016/s0008-6363(03)00500-5 · 2003 · External reference
Asymmetric dimethylarginine, derangements of the endothelial nitric oxide synthase pathway, and cardiovascular diseases
10.1055/s-2000-13210 · 2000 · External reference
LDL cholesterol upregulates synthesis of asymmetrical dimethylarginine in human endothelial cells: involvement of S-adenosylmethionine-dependent methyltransferases
10.1161/01.res.87.2.99 · 2000 · External reference
Novel mechanism for endothelial dysfunction: dysregulation of dimethylarginine dimethylaminohydrolase
10.1161/01.cir.99.24.3092 · 1999 · External reference
S-Nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: further interactions between nitric oxide synthase and dimethylarginine dimethylaminohydrolase
10.1073/pnas.212269799 · 2002 · External reference
Impaired nitric oxide synthase pathway in diabetes mellitus: role of asymmetric dimethylarginine and dimethylarginine dimethylaminohydrolase
10.1161/01.cir.0000027109.14149.67 · 2002 · External reference
Homocysteine impairs the nitric oxide synthase pathway: role of asymmetric dimethylarginine
10.1161/hc4601.098514 · 2001 · External reference
Evidence for dysregulation of dimethylarginine dimethylaminohydrolase I in chronic hypoxia-induced pulmonary hypertension
10.1161/01.cir.0000089087.25930.ff · 2003 · External reference
Asymmetrical dimethylarginine: the Uber marker?
10.1161/01.cir.0000126823.07732.d5 · 2004 · External reference
The DDAH/ADMA/NOS pathway
10.1016/s1567-5688(03)00032-1 · 2003 · External reference
The liver is an important organ in the metabolism of asymmetrical dimethylarginine (ADMA)
10.1054/clnu.2002.0612 · 2003 · External reference
Effect of shear stress on asymmetric dimethylarginine release from vascular endothelial cells
10.1161/01.hyp.0000097805.05108.16 · 2003 · External reference
ADMA and oxidative stress
10.1016/s1567-5688(03)00033-3 · 2003 · External reference
Regulation of cytokine-induced nitric oxide synthesis by asymmetric dimethylarginine: role of dimethylarginine dimethylaminohydrolase
10.1161/01.res.0000052990.68216.ef · 2003 · External reference
Plasma asymmetric dimethylarginine and coronary and peripheral endothelial dysfunction in hypertensive patients
10.1016/j.amjhyper.2004.05.005 · 2004 · External reference
Elevated plasma asymmetric dimethylarginine as a marker of cardiovascular morbidity in early diabetic nephropathy in type 1 diabetes
10.2337/diacare.27.3.765 · 2004 · External reference
Asymmetric dimethyl-l-arginine (ADMA): a possible link between homocyst(e)ine and endothelial dysfunction
10.2174/1389200052997393 · 2005 · External reference
The role of NOS3 in stem cell mobilization
10.1016/j.molmed.2004.07.007 · 2004 · External reference
Essential role of endothelial nitric oxide synthase for mobilization of stem and progenitor cells
10.1038/nm948 · 2003 · External reference
Increased circulating concentrations of asymmetric dimethyl arginine (ADMA), an endogenous inhibitor of nitric oxide synthesis in preeclampsia
10.1080/j.1600-0412.1998.770805.x · 1998 · External reference
Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia
10.1016/s0140-6736(03)13177-7 · 2003 · External reference
Concentrations of homocysteine, related metabolites and asymmetric dimethylarginine in preeclamptic women with poor nutritional status
10.1515/cclm.2005.198 · 2005 · External reference
Endogenous inhibitors of nitric oxide and preeclampsia: a review
10.1080/14767050600852171 · 2006 · External reference
Levels of dimethylarginines and cytokines in mild and severe preeclampsia
10.1080/j.1600-0412.2001.800703.x · 2001 · External reference
Plasma concentrations of asymmetric dimethylarginine, a natural inhibitor of nitric oxide synthase, in normal pregnancy and preeclampsia
10.1016/s0002-9378(98)70437-5 · 1998 · External reference
Elevated asymmetric dimethylarginine concentrations precede clinical preeclampsia, but not pregnancies with small-for-gestational-age infants
10.1016/j.ajog.2007.05.052 · 2008 · External reference
Effects of acute l-arginine infusion on non-stress test in hypertensive pregnant women
10.1080/14767050412331282266 · 2004 · External reference
Dietary supplementation with l-arginine or placebo in women with pre-eclampsia
2004 · External reference
Effects of prolonged oral supplementation with l-arginine on blood pressure and nitric oxide synthesis in preeclampsia
10.1111/j.1365-2362.2005.01445.x · 2005 · External reference
l-Arginine infusion reduces blood pressure in preeclamptic women through nitric oxide release
10.1016/s1071-5576(99)00017-9 · 1999 · External reference
Vitamins C and E to prevent complications of pregnancy-associated hypertension
10.1056/nejmoa0908056 · 2010 · External reference