Research graph
References from Protein biomarkers in precision medicine: Integrating structure, dynamics, and structural proteomics for personalized therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
The multifaceted role of neurofilament light chain protein in non-primary neurological diseases
2022 · External reference
Biomarkers as biomedical bioindicators: Approaches and techniques for the detection, analysis, and validation of novel biomarkers of diseases
10.3390/pharmaceutics15061630 · 2023 · External reference
Practicing precision medicine with intelligently integrative clinical and multi-omics data analysis
10.1186/s40246-020-00287-z · 2020 · External reference
When protein structure embedding meets large language models
10.3390/genes15010025 · 2023 · External reference
Unresolved reference
2016 · External reference
Significance of type II collagen posttranslational modifications: From autoantigenesis to improved diagnosis and treatment of rheumatoid arthritis
10.3390/ijms24129884 · 2023 · External reference
Biomarkers for Alzheimer's disease: Current status and prospects for the future
10.1111/joim.12816 · 2018 · External reference
The structural context of posttranslational modifications at a proteome-wide scale
10.1371/journal.pbio.3001636 · 2022 · External reference
Cancer in a drop: Advances in liquid biopsy in 2024
2025 · External reference
Biomarkers in personalized medicine: Discovery and delivery
2016 · External reference
Circulating cell-free DNA and circulating tumor cells as prognostic and predictive biomarkers in advanced non-small cell lung cancer patients treated with first-line chemotherapy
10.3390/ijms18051035 · 2017 · External reference
STARD 2015 guidelines for reporting diagnostic accuracy studies: explanation and elaboration
10.1136/bmjopen-2016-012799 · 2016 · External reference
Liquid biopsy: The challenges of a revolutionary approach in oncology
10.3390/ijms26115013 · 2025 · External reference
Advances in mass spectrometry-based clinical biomarker discovery
10.1186/s12014-015-9102-9 · 2016 · External reference
Tumor-derived extracellular vesicles as liquid biopsy for diagnosis and prognosis of solid tumors: Their clinical utility and reliability as tumor biomarkers
10.3390/cancers16132462 · 2024 · External reference
A systematic pipeline of protein structure selection for computer‐aided drug discovery: A case study on T790M/L858R mutant EGFR structures
10.1002/pro.4740 · 2023 · External reference
Proteomics methodologies: The search of protein biomarkers using microfluidic systems coupled to mass spectrometry
10.3390/proteomes11020019 · 2023 · External reference
An integrative analysis of functional consequences of PKD2 missense variants on RNA and protein structures: A computational approach
10.1186/s43042-024-00593-4 · 2024 · External reference
Biomarkers in stress-related diseases/disorders: Diagnostic, prognostic, and therapeutic values
10.3389/fmolb.2019.00091 · 2019 · External reference
Ethical challenges in biomarker research and precision medicine: A qualitative study in dermatology
10.1186/s12910-025-01258-6 · 2025 · External reference
Unlocking the power of precision medicine: Exploring the role of biomarkers in cancer management
10.1186/s43094-023-00573-2 · 2024 · External reference
Endothelial cell dysfunction and the pathobiology of atherosclerosis
10.1161/circresaha.115.306301 · 2016 · External reference
Cancer biomarker discovery and validation
2015 · External reference
Quantitative protein biomarker panels: A path to improved clinical practice through proteomics
2023 · External reference
Circulating tumor cells and DNA as liquid biopsies
10.1186/gm477 · 2013 · External reference
A structural perspective on targeting the RTK/Ras/MAP kinase pathway in cancer
10.1002/pro.4125 · 2021 · External reference
Insights into protein structural, physicochemical, and functional consequences of missense variants in 1,330 disease-associated human genes 693259
2019 · External reference
Metabolomics toward personalized medicine
2017 · External reference
Deep learning for protein structure prediction and design: Progress and applications
2024 · External reference
The evolution of analytical techniques for multiplex analysis of protein biomarkers
2025 · External reference
Recommendations for development and validation of fit-for-purpose biomarker assays using Western blotting
10.1208/s12248-024-00946-2 · 2024 · External reference
What is precision medicine?
2017 · External reference
The evolving role of hydrogen/deuterium exchange mass spectrometry in early-stage drug discovery
10.1016/j.sbi.2025.103051 · 2025 · External reference
Development and validation of a protein risk score for mortality in heart failure
2024 · External reference
Introduction: Biomarkers in translational and personalized medicine
2013 · External reference
A comprehensive review and comparison of existing computational methods for protein function prediction
10.1093/bib/bbae289 · 2024 · External reference
Synaptic degeneration and neurogranin in the pathophysiology of Alzheimer's disease
2016 · External reference
Mass spectrometry structural proteomics enabled by limited proteolysis and cross-linking
2024 · External reference
Recent advances in mass spectrometry-based clinical proteomics: Applications to cancer research
10.1186/s12014-020-09283-w · 2020 · External reference
What is a biomarker? From its discovery to clinical application
10.2478/v10011-011-0029-z · 2011 · External reference
An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery
10.1080/17460441.2017.1363734 · 2017 · External reference
Biomarkers: Potential uses and limitations
10.1602/neurorx.1.2.182 · 2004 · External reference
Skin-interfaced wearable sweat sensors for precision medicine
2023 · External reference
Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC
10.1016/j.bioorg.2022.106219 · 2022 · External reference
Dual biomarker strategies for liquid biopsy: Integrating circulating tumor cells and circulating tumor DNA for enhanced tumor monitoring
10.3390/bios15020074 · 2025 · External reference
Current status and future directions: The application of artificial intelligence and machine learning for precision medicine
2023 · External reference
Precision medicine: Concept and tools
10.1016/j.mjafi.2021.06.021 · 2021 · External reference
HDX-MS: An analytical tool to capture protein motion in action
10.3390/biomedicines8070224 · 2020 · External reference
Omics-based investigations of breast cancer
10.3390/molecules28124768 · 2023 · External reference
Protein structural consequences of DNA mutational signatures: A meta-analysis of somatic variants and deep mutational scanning data
2021 · External reference
Surface plasmon resonance: A versatile technique for biosensor applications
10.3390/s150510481 · 2015 · External reference
Liquid biopsy: Current technology and clinical applications
10.1186/s13045-022-01351-y · 2022 · External reference
Liquid biopsy in cancer management: Integrating diagnostics and clinical applications
2024 · External reference
Driving therapeutic innovation in neurodegenerative disease with hydrogen deuterium eXchange mass spectrometry
10.1016/j.mcpro.2025.101017 · 2025 · External reference
Statistical evaluation of a biomarker
10.1097/aln.0b013e3181d47604 · 2010 · External reference
Extracellular vesicles as liquid biopsy biomarkers across the cancer journey: From early detection to recurrence
10.1093/clinchem/hvad176 · 2024 · External reference
Impact of clinical practice gaps on the implementation of personalized medicine in advanced non-small-cell lung cancer
2022 · External reference
Functional and structural features of disease-related protein variants
10.3390/ijms20071530 · 2019 · External reference
Circulating miRNAs as liquid biopsy biomarkers for diagnosis in colorectal cancer: A systematic review and meta-analysis
10.3389/fgene.2025.1574586 · 2025 · External reference
Limitations and opportunities of technologies for the analysis of cell-free DNA in cancer diagnostics
10.1038/s41551-021-00837-3 · 2022 · External reference
Technical advances in circulating cell-free DNA detection and analysis for personalized medicine in patient care
10.3390/biom14040498 · 2024 · External reference
Biomarker-based stratification: Advancing precision medicine through targeted patient classification
2024 · External reference
Patient-derived tumor organoids: A new avenue for preclinical research and precision medicine in oncology
2024 · External reference
Heterogeneity in precision oncology
10.1017/pcm.2023.23 · 2024 · External reference
Beyond ctDNA: Integrating multi-analyte liquid biopsies for comprehensive cancer management
2025 · External reference
Enhancing detection and monitoring of circulating tumor cells: Integrative approaches in liquid biopsy advances
10.1016/j.jlb.2025.100297 · 2025 · External reference
Challenges in bridging the gap between protein structure prediction and functional interpretation
2023 · External reference
Biomarkers for bone tumors: Discovery from genomics and proteomics studies and their challenges
10.2119/molmed.2015.00183 · 2015 · External reference
Structural proteomic profiling of cerebrospinal fluids to reveal novel conformational biomarkers for alzheimer's disease
10.1021/jasms.2c00332 · 2023 · External reference
Precision medicine: Disease subtyping and tailored treatment
10.3390/cancers15153837 · 2023 · External reference
Native dynamics and allosteric responses in PTP1B probed by high-resolution HDX-MS
10.1002/pro.5024 · 2024 · External reference
Translational biomarker discovery in clinical metabolomics: An introductory tutorial
10.1007/s11306-012-0482-9 · 2012 · External reference
Universal nanopore sensor for amplification-free and label-free detection of molecular biomarkers
10.1021/acssensors.5c00926 · 2025 · External reference
Structural basis of AZD9291 selectivity for EGFR T790M
10.1021/acs.jmedchem.0c00891 · 2020 · External reference
Liquid biopsies in cancer
10.1186/s43556-025-00257-8 · 2025 · External reference
Post-Translational modifications of G protein–coupled receptors revealed by proteomics and structural biology
2022 · External reference
AlphaFold2 in biomedical research: Facilitating the development of diagnostic strategies for disease
10.3389/fmolb.2024.1414916 · 2024 · External reference
Proteomics of post-translational modifications in colorectal cancer: Discovery of new biomarkers
10.1016/j.bbcan.2022.188735 · 2022 · External reference
Plasma/serum proteomics based on mass spectrometry
2024 · External reference
