Research graph
References from Spit it out: rhoptry organelles in Plasmodium sporozoites. Local targets link to admitted publications; unresolved targets remain external evidence.
Rhoptry biogenesis in Plasmodium sporozoites is uncoupled from mitosis and forms distinct pairs
10.1083/jcb.202602062 · 2026 · External reference
Gliding motility powers invasion and egress in Apicomplexa
10.1038/nrmicro.2017.86 · 2017 · External reference
Secretory organelle function in the Plasmodium sporozoite
10.1016/j.pt.2021.01.008 · 2021 · External reference
Plasmodium sporozoites on the move: switching from cell traversal to productive invasion of hepatocytes
10.1111/mmi.14645 · 2021 · External reference
Vesicle trafficking during sporozoite development in Plasmodium berghei: ultrastructural evidence for a novel trafficking mechanism
10.1017/s0031182007003629 · 2008 · External reference
An ultrastructural study of the sporogonic development of Plasmodium falciparum in Anopheles gambiae
10.1016/0035-9203(78)90167-0 · 1978 · External reference
Three-dimensional electron microscopy analysis reveals endopolygeny-like nuclear architecture segregation in Plasmodium oocyst development
10.1016/j.parint.2019.102034 · 2020 · External reference
Essential nucleus-apical pole linkage maintains division fidelity during Plasmodium progeny formation
10.1038/s44318-026-00836-7 · 2026 · External reference
The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts
10.1371/journal.ppat.1010643 · 2022 · External reference
Ultrastructure of rhoptry development in Plasmodium falciparum erythrocytic schizonts
10.1017/s0031182099006320 · 2000 · External reference
Electron tomography of Plasmodium falciparum merozoites reveals core cellular events that underpin erythrocyte invasion
10.1111/cmi.12132 · 2013 · External reference
Plasmodium rhoptry proteins: why order is important
10.1016/j.pt.2013.03.003 · 2013 · External reference
CD81 is required for rhoptry discharge during host cell invasion by Plasmodium yoelii sporozoites
10.1111/cmi.12309 · 2014 · External reference
Expression and localization profiles of rhoptry proteins in Plasmodium berghei sporozoites
10.3389/fcimb.2019.00316 · 2019 · External reference
Super-resolution dissection of coordinated events during malaria parasite invasion of the human erythrocyte
10.1016/j.chom.2010.12.003 · 2011 · External reference
Subcompartmentalisation of proteins in the rhoptries correlates with ordered events of erythrocyte invasion by the blood stage malaria parasite
10.1371/journal.pone.0046160 · 2012 · External reference
An Alveolata secretory machinery adapted to parasite host cell invasion
10.1038/s41564-020-00854-z · 2021 · External reference
Rhoptry secretion system structure and priming in Plasmodium falciparum revealed using in situ cryo-electron tomography
10.1038/s41564-022-01171-3 · 2022 · External reference
Cryogenic electron tomography reveals novel structures in the apical complex of Plasmodium falciparum
10.1128/mbio.02864-23 · 2024 · External reference
In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems
10.1038/s41467-021-25309-9 · 2021 · External reference
Proteome analysis of rhoptry-enriched fractions isolated from Plasmodium merozoites
10.1021/pr049926m · 2004 · External reference
The spatial proteome of the Plasmodium falciparum schizont illuminates the composition and evolutionary trajectories of its organelles
10.1038/s41467-026-73664-2 · 2026 · External reference
Total and putative surface proteomics of malaria parasite salivary gland sporozoites
10.1074/mcp.m112.024505 · 2013 · External reference
Proteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites
10.1371/journal.pntd.0005791 · 2017 · External reference
In-depth proteomic analysis of Plasmodium berghei sporozoites using trapped ion mobility spectrometry with parallel accumulation-serial fragmentation
10.1002/pmic.202000305 · 2021 · External reference
Identification of a novel rhoptry protein expressed predominantly in Plasmodium sporozoites
10.3389/fcimb.2025.1749149 · 2026 · External reference
The CLAMP-linked invasion protein (CLIP) plays an essential role in Plasmodium berghei zoites
2026 · External reference
Rhoptry neck protein 2 expressed in Plasmodium sporozoites plays a crucial role during invasion of mosquito salivary glands
10.1111/cmi.12964 · 2019 · External reference
Detection of the rhoptry neck protein complex in Plasmodium sporozoites and its contribution to sporozoite invasion of salivary glands
10.1128/msphere.00325-20 · 2020 · External reference
Rhoptry neck protein 4 plays important roles during Plasmodium sporozoite infection of the mammalian liver
10.1128/msphere.00587-22 · 2023 · External reference
Expression and localization of rhoptry neck protein 5 in merozoites and sporozoites of Plasmodium yoelii
10.1016/j.parint.2014.07.013 · 2014 · External reference
Plasmodium berghei rhoptry neck protein 6 maintains parasite infectivity and virulence
10.1128/mbio.01941-25 · 2025 · External reference
Rhoptry neck protein 11 has crucial roles during malaria parasite sporozoite invasion of salivary glands and hepatocytes
10.1016/j.ijpara.2019.05.001 · 2019 · External reference
Plasmodium RON12 localizes to the rhoptry body in sporozoites
10.1016/j.parint.2018.10.001 · 2019 · External reference
Localisation and timing of expression of putative Plasmodium berghei rhoptry proteins in merozoites and sporozoites
10.1016/j.molbiopara.2009.02.009 · 2009 · External reference
Proteomic analysis of Plasmodium merosomes: the link between liver and blood stages in malaria
10.1021/acs.jproteome.9b00324 · 2019 · External reference
The Plasmodium falciparum rhoptry protein RhopH3 plays essential roles in host cell invasion and nutrient uptake
10.7554/elife.23239 · 2017 · External reference
Plasmodium falciparum parasites deploy RhopH2 into the host erythrocyte to obtain nutrients, grow and replicate
10.7554/elife.23217 · 2017 · External reference
The moving junction of apicomplexan parasites: a key structure for invasion
10.1111/j.1462-5822.2011.01597.x · 2011 · External reference
Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites
10.1016/j.parint.2008.09.005 · 2009 · External reference
Revealing the sequence and resulting cellular morphology of receptor-ligand interactions during Plasmodium falciparum invasion of erythrocytes
10.1371/journal.ppat.1004670 · 2015 · External reference
Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites
10.1074/jbc.m109.080770 · 2010 · External reference
The RON2-AMA1 interaction is a critical step in moving junction-dependent invasion by apicomplexan parasites
10.1371/journal.ppat.1001276 · 2011 · External reference
Export of a Toxoplasma gondii rhoptry neck protein complex at the host cell membrane to form the moving junction during invasion
10.1371/journal.ppat.1000309 · 2009 · External reference
The dimerisable Cre recombinase allows conditional genome editing in the mosquito stages of Plasmodium berghei
10.1371/journal.pone.0236616 · 2020 · External reference
Structural basis for host membrane binding and remodeling by invading malaria parasites
10.1016/j.cell.2026.06.012 · 2026 · External reference
AMA1 and MAEBL are important for Plasmodium falciparum sporozoite infection of the liver
10.1111/cmi.12745 · 2017 · External reference
Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion
10.1038/ncomms3552 · 2013 · External reference
Plasmodium RON11 triggers biogenesis of the merozoite rhoptry pair and is essential for erythrocyte invasion
10.1371/journal.pbio.3002801 · 2024 · External reference
RON12, a novel Plasmodium-specific rhoptry neck protein important for parasite proliferation
10.1111/cmi.12181 · 2014 · External reference
The sporozoite’s journey through the mosquito: a critical examination of host and parasite factors required for salivary gland invasion
10.3389/fevo.2019.00284 · 2019 · External reference
The journey of malaria sporozoites in the mosquito salivary gland
10.1111/j.1550-7408.1994.tb01523.x · 1994 · External reference
Malaria sporozoites traverse host cells within transient vacuoles
10.1016/j.chom.2015.10.006 · 2015 · External reference
Migration of Plasmodium sporozoites through cells before infection
10.1126/science.291.5501.141 · 2001 · External reference
Loss of host cell plasma membrane integrity following cell traversal by Plasmodium sporozoites in the skin
10.1016/j.parint.2013.07.009 · 2014 · External reference
A Plasmodium sporozoite protein with a membrane attack complex domain is required for breaching the liver sinusoidal cell layer prior to hepatocyte infection
10.1111/j.1462-5822.2004.00447.x · 2005 · External reference
Cell-passage activity is required for the malarial parasite to cross the liver sinusoidal cell layer
10.1371/journal.pbio.0020004 · 2004 · External reference
High-resolution proteomics unveils salivary gland disruption and saliva-hemolymph protein exchange in Plasmodium-infected mosquitoes
2025 · External reference
Molecular interactions between Anopheles stephensi midgut cells and Plasmodium berghei: the time bomb theory of ookinete invasion of mosquitoes
10.1093/emboj/19.22.6030 · 2000 · External reference
Plasmodium cysteine repeat modular proteins 3 and 4 are essential for malaria parasite transmission from the mosquito to the host
10.1186/1475-2875-10-71 · 2011 · External reference
Plasmodium cysteine repeat modular proteins 1–4: complex proteins with roles throughout the malaria parasite life cycle
10.1111/j.1462-5822.2006.00885.x · 2007 · External reference
The transmembrane isoform of Plasmodium falciparum MAEBL is essential for the invasion of anopheles salivary glands
10.1371/journal.pone.0002287 · 2008 · External reference
MAEBL is essential for malarial sporozoite infection of the mosquito salivary gland
10.1084/jem.20011876 · 2002 · External reference
Plasmodium sporozoites require the protein B9 to invade hepatocytes
10.1016/j.isci.2023.106056 · 2023 · External reference
Plasticity and redundancy among AMA–RON pairs ensure host cell entry of Toxoplasma parasites
10.1038/ncomms5098 · 2014 · External reference
Plasmodium P36 determines host cell receptor usage during sporozoite invasion
10.7554/elife.25903 · 2017 · External reference
Two proteins with 6-cys motifs are required for malarial parasites to commit to infection of the hepatocyte
10.1111/j.1365-2958.2005.04801.x · 2005 · External reference
The micronemal Plasmodium proteins P36 and P52 act in concert to establish the replication-permissive compartment within infected hepatocytes
10.3389/fcimb.2018.00413 · 2018 · External reference
Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity
10.1038/nm808 · 2003 · External reference
A structure-based epitope tagging approach identifies vulnerable sites on the malarial P36-P52 protein complex for antibody-mediated neutralization of Plasmodium sporozoites
10.1371/journal.ppat.1014418 · 2026 · External reference
Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection
10.1038/nm.3424 · 2014 · External reference
Host cell cytosolic immune response during Plasmodium liver stage development
10.1093/femsre/fuy007 · 2018 · External reference
Plasmodium UIS3 sequesters host LC3 to avoid elimination by autophagy in hepatocytes
10.1038/s41564-017-0054-x · 2018 · External reference
Structured to conquer: transport across the Plasmodium parasitophorous vacuole
10.1016/j.mib.2021.07.010 · 2021 · External reference
The Plasmodium rhoptry associated protein complex is important for parasitophorous vacuole membrane structure and intraerythrocytic parasite growth
10.1111/cmi.12733 · 2017 · External reference
Structure guided mimicry of an essential P. falciparum receptor-ligand complex enhances cross neutralizing antibodies
10.1038/s41467-023-41636-5 · 2023 · External reference
