Research graph
References from State-matched redox nanomedicine for cell fate control and multicompartment therapeutic windows. Local targets link to admitted publications; unresolved targets remain external evidence.
The pleiotropic functions of reactive oxygen species in cancer
10.1038/s43018-024-00738-9 · 2024 · External reference
Fundamentals of redox regulation in biology
10.1038/s41580-024-00730-2 · 2024 · External reference
Targeting ROS in cancer: rationale and strategies
10.1038/s41573-024-00979-4 · 2024 · External reference
Reduction-responsive RNAi nanoplatform for enhanced cancer sonoimmunotherapy via dual inhibition of mitophagy and Nrf2 pathways
10.7150/thno.112649 · 2025 · External reference
Engineered hypoxia-responsive albumin nanoparticles mediating mitophagy regulation for cancer therapy
10.1038/s41467-025-55905-y · 2025 · External reference
Self-adaptive single-atom catalyst boosting selective ferroptosis in tumor cells
10.1021/acsnano.1c08464 · 2022 · External reference
Activatable chemodynamic theranostics through molecular imaging-energized companion diagnostics
10.1021/acs.nanolett.5c01444 · 2025 · External reference
Interpretable radiomics model predicts nanomedicine tumor accumulation using routine medical imaging
2025 · External reference
Nanosensors monitor intracellular GSH depletion: GSH triggers Cu(II) for tumor imaging and inhibition
2024 · External reference
A light-activatable theranostic combination for ratiometric hypoxia imaging and oxygen-deprived drug activity enhancement
10.1038/s41467-023-44429-y · 2024 · External reference
Specific and long-term luminescent monitoring of hydrogen peroxide in tumor metastasis
2023 · External reference
A multiple stimuli-responsive NanoCRISPR overcomes tumor redox heterogeneity to augment photodynamic therapy
10.1021/acsnano.3c00940 · 2023 · External reference
Personalized oncology by in vivo chemical imaging: photoacoustic mapping of tumor oxygen predicts radiotherapy efficacy
10.1021/acsnano.2c09502 · 2023 · External reference
NIR-II ratiometric chemiluminescent/fluorescent reporters for real-time monitoring and evaluating cancer photodynamic therapy efficacy
10.1002/smll.202202551 · 2022 · External reference
Ultrasmall magneto-chiral cobalt hydroxide nanoparticles enable dynamic detection of reactive oxygen species in vivo
10.1021/jacs.1c09986 · 2022 · External reference
Nanomaterial-based regulation of redox metabolism for enhancing cancer therapy
10.1039/d4cs00404c · 2024 · External reference
Applications and enhancement strategies of ROS-based non-invasive therapies in cancer treatment
10.1016/j.redox.2025.103515 · 2025 · External reference
Targeting oxidative stress-mediated regulated cell death as a vulnerability in cancer
10.1016/j.redox.2025.103686 · 2025 · External reference
Nanomaterials-induced redox imbalance: challenged and opportunities for nanomaterials in cancer therapy
2024 · External reference
Advancing engineering design strategies for targeted cancer nanomedicine
10.1038/s41568-025-00847-2 · 2025 · External reference
Meta-analysis of nanoparticle distribution in tumors and major organs in tumor-bearing mice
10.1021/acsnano.3c04037 · 2023 · External reference
Controlling nanoparticle-induced endothelial leakiness with the protein corona
10.1039/d4nr01311e · 2024 · External reference
Nanomedicine tumor targeting
2024 · External reference
Transvascular transport of nanocarriers for tumor delivery
10.1038/s41467-024-52416-0 · 2024 · External reference
Engineering the protein corona: strategies, effects, and future directions in nanoparticle therapeutics
2024 · External reference
The role of patient-specific variables in protein corona formation and therapeutic efficacy in nanomedicine
10.1186/s12951-024-02954-y · 2024 · External reference
Tumor abnormality-oriented nanomedicine design
10.1021/acs.chemrev.3c00062 · 2023 · External reference
Barrier permeation and improved nanomedicine delivery in tumor microenvironments
10.1016/j.canlet.2023.216166 · 2023 · External reference
Progress on the pathological tissue microenvironment barrier-modulated nanomedicine
10.1016/j.addr.2023.115051 · 2023 · External reference
Overcoming tumor microenvironment obstacles: current approaches for boosting nanodrug delivery
10.1016/j.actbio.2023.05.043 · 2023 · External reference
Meta-analysis of material properties influencing nanoparticle plasma pharmacokinetics
2023 · External reference
Mitochondria-targeting Type-I photodynamic therapy based on phenothiazine for realizing enhanced immunogenic cancer cell death via mitochondrial oxidative stress
10.2147/ijn.s494970 · 2025 · External reference
Molecular engineering strategies for fabricating type-I mitochondria-targeted aggregation-induced emission photosensitizers for apoptosis-ferroptosis synergistically boosting photodynamic therapy
10.1016/j.jcis.2025.137680 · 2025 · External reference
An on-Demand oxygen nano-vehicle sensitizing protein and nucleic acid drug augment immunotherapy
2025 · External reference
Hypoxia-responsive albumin nanoparticles co-delivering banoxantrone and STING agonist enhance immunotherapy of high-intensity focused ultrasound
2025 · External reference
An oxygen-generating nanoplatform remodels the immunosuppressive tumor microenvironment via synergistic lactate depletion and sonodynamic therapy
10.1186/s12951-025-03524-6 · 2025 · External reference
Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions
10.1038/s41392-023-01332-8 · 2023 · External reference
Breaking the siege of hypoxia and lactate: carrier-free flexible dual-enzyme protein vesicle to ignite photodynamic-immune storm in head and neck squamous cell carcinoma
2025 · External reference
A tumor microenvironment-responsive self-oxygenating nanoplatform for dual-enhanced cuproptosis and sonodynamic synergistic immunotherapy
10.1021/acsnano.5c12847 · 2025 · External reference
Self-delivery photodynamic-hypoxia alleviating nanomedicine synergizes with anti-PD-L1 for cancer immunotherapy
2023 · External reference
Endoplasmic reticulum-targeted photodynamic therapy synergizes with rapamycin to induce autophagic cancer cell death
10.1016/j.actbio.2026.04.062 · 2026 · External reference
In situ transformable nanoparticle effectively suppresses bladder cancer by damaging mitochondria and blocking mitochondrial autophagy flux
2025 · External reference
Lysosome-mitochondria Cascade targeting nanoparticle drives robust pyroptosis for cancer immunotherapy
10.1021/jacs.4c12264 · 2024 · External reference
Albumins constrainting the conformation of mitochondria-targeted photosensitizers for tumor-specific photodynamic therapy
10.1016/j.biomaterials.2024.122914 · 2025 · External reference
A mitochondria-targeted supramolecular nanoplatform for peroxynitrite-potentiated oxidative therapy of orthotopic hepatoma
10.1016/j.biomaterials.2022.121854 · 2022 · External reference
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
10.1038/s41418-017-0012-4 · 2018 · External reference
The biochemical pathways of apoptotic, necroptotic, pyroptotic, and ferroptotic cell death
10.1016/j.molcel.2023.11.040 · 2024 · External reference
Mechanistic insights into gasdermin-mediated pyroptosis
10.1038/s41580-025-00837-0 · 2025 · External reference
A guideline on the molecular ecosystem regulating ferroptosis
10.1038/s41556-024-01360-8 · 2024 · External reference
A Metabolic NanoLock strategy enhances cuproptosis in hypoxic tumors by enforcing mitochondrial respiration and suppressing glycolysis
10.1016/j.actbio.2026.05.046 · 2026 · External reference
Light-triggered carbon monoxide-induced activation of enhanced ferritinophagy-mediated ferroptosis for bone metastases therapy
2025 · External reference
Self-amplifying nanomedicine reprograms redox metabolism to trigger immunogenic ferroptosis in colon cancer: multiomics identifies AMPD3 as a novel regulator
10.1016/j.biomaterials.2026.124196 · 2026 · External reference
A catalytic redox-cycling nanoreactor enables robust oxidative stress amplification for synergistic tumor apoptosis and ferroptosis
10.1016/j.actbio.2026.05.045 · 2026 · External reference
Mitochondria-targeted photothermal-chemodynamic therapy enhances checkpoint blockade immunotherapy on colon cancer
2025 · External reference
A locally-adapted nanoreactor for autophagy inhibition-enhanced cascade starvation-chemodynamic therapy
10.1016/j.jcis.2025.137820 · 2025 · External reference
Boosting ferroptosis therapy by sorafenib and ML385 loaded CuFe2O4 nanozymes
10.1016/j.colsurfb.2025.114968 · 2025 · External reference
Nickel atom-clusters nanozyme for boosting ferroptosis tumor therapy
2024 · External reference
Nanozyme as tumor energy homeostasis disruptor to augment Cascade catalytic therapy
10.1021/acsnano.4c09982 · 2024 · External reference
Zinc-based ROS amplifiers trigger cancer chemodynamic/ion interference therapy through self-cascade catalysis
2024 · External reference
Boosting chemodynamic therapy by tumor-targeting and cellular redox homeostasis-disrupting nanoparticles
10.1021/acsami.2c11091 · 2022 · External reference
Bacteria-mediated tumor-targeting delivery of multienzyme-mimicking covalent organic frameworks promoting pyroptosis for combinatorial sono-catalytic immunotherapy
2024 · External reference
Mitochondria-targeted nanosystem enhances radio-radiodynamic-chemodynamic therapy on triple negative breast cancer
10.1021/acsami.3c02361 · 2023 · External reference
Radiotherapy-mediated redox homeostasis-controllable nanomedicine for enhanced ferroptosis sensitivity in tumor therapy
10.1016/j.actbio.2023.01.022 · 2023 · External reference
A nanoreactor boosts chemodynamic therapy and ferroptosis for synergistic cancer therapy using molecular amplifier dihydroartemisinin
10.1186/s12951-022-01455-0 · 2022 · External reference
Mitochondria-targeting pseudo-stealthy nanophotosensitizer as a potent immunogenic cell death inducer to unleash the cancer-immunity cycle for melanoma therapy
10.1016/j.actbio.2025.07.035 · 2025 · External reference
Biomimetic cancer-targeting nanoplatform boosting AIEgens-Based photodynamic therapy and ferroptosis by disrupting redox-homeostasis
10.1021/acsbiomaterials.4c00376 · 2024 · External reference
Immunomodulatory-photodynamic nanostimulators for invoking pyroptosis to augment tumor immunotherapy
10.1002/adhm.202201233 · 2022 · External reference
ROS-responsive nanoparticle delivery of mRNA and photosensitizer for combinatorial cancer therapy
10.1021/acs.nanolett.2c03784 · 2023 · External reference
Glutaminolysis inhibition boosts photodynamic therapy to eliminate cancer stem cells
10.1016/j.biomaterials.2024.122497 · 2024 · External reference
Cascade-penetrating domino-ferroptosis nano inducer synergizes with sonodynamic therapy for anaplastic thyroid cancer
2025 · External reference
Multifunctional nanoparticles for enhanced sonodynamic-chemodynamic immunotherapy with glutathione depletion
10.2217/nnm-2023-0218 · 2024 · External reference
Carrier-free self-assembly nano-sonosensitizers for sonodynamic-amplified cuproptosis-ferroptosis in glioblastoma therapy
2024 · External reference
PtMo-Au metalloenzymes regulated tumor microenvironment for enhanced sonodynamic/chemodynamic/starvation synergistic therapy
10.1002/smll.202303365 · 2023 · External reference
Self-assembled aza-boron-dipyrromethene for ferroptosis-boosted sonodynamic therapy
10.1002/anie.202210174 · 2022 · External reference
Active-targeting biomimetic nanosystem for prostate cancer enhances radiotherapy efficacy by inducing ferroptosis
10.1186/s12951-025-03879-w · 2025 · External reference
Dual inhibition of oxidative phosphorylation and glycolysis using a hyaluronic acid nanoparticle NOX inhibitor enhanced response to radiotherapy in colorectal cancer
10.1016/j.biomaterials.2025.123437 · 2025 · External reference
Mitochondria-targeting nanozyme for catalytical therapy and radiotherapy with activation of cGAS-STING
10.1016/j.colsurfb.2024.114137 · 2024 · External reference
Nanocarriers targeting circular RNA ADARB1 boost radiosensitivity of nasopharyngeal carcinoma through synergically promoting ferroptosis
10.1021/acsnano.4c07676 · 2024 · External reference
Ferroptosis: mechanisms, biology and role in disease
10.1038/s41580-020-00324-8 · 2021 · External reference
DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
10.1038/s41586-021-03539-7 · 2021 · External reference
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
10.1038/s41586-019-1705-2 · 2019 · External reference
Platelet membrane biomimetic nanomedicine induces dual glutathione consumption for enhancing cancer radioimmunotherapy
2024 · External reference
Oxidative stress amplifiers as immunogenic cell death nanoinducers disrupting mitochondrial redox homeostasis for cancer immunotherapy
2023 · External reference
The epitranscriptional factor PCIF1 orchestrates CD8+ T cell ferroptosis and activation to control antitumor immunity
10.1038/s41590-024-02047-w · 2025 · External reference
Ferroptotic mechanisms and therapeutic targeting of iron metabolism and lipid peroxidation in the kidney
10.1038/s41581-023-00689-x · 2023 · External reference
A mitochondria-targeted nanozyme platform for multi-pathway tumor therapy via ferroptosis and cuproptosis regulation
2025 · External reference
Photo-activated autophagy-associated tumour cell death by lysosome impairment based on manganese-doped graphene quantum dots
2023 · External reference
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
10.1080/15548627.2020.1797280 · 2021 · External reference
Apoptosis and cuproptosis Co-activated Copper-based metal-organic frameworks for cancer therapy
10.1186/s12951-024-02828-3 · 2024 · External reference
Co-delivery of sorafenib and an FSP1 inhibitor triggers dual ferroptosis in tumor cells and immunosuppressive macrophages for enhanced immunotherapy in mouse models of hepatocellular carcinoma
10.1038/s41467-025-65056-9 · 2025 · External reference
Targeting cuproplasia and cuproptosis in cancer
10.1038/s41571-024-00876-0 · 2024 · External reference
Copper induces cell death by targeting lipoylated TCA cycle proteins
10.1126/science.abf0529 · 2022 · External reference
Consensus guidelines for the definition, detection and interpretation of immunogenic cell death
10.1136/jitc-2019-000337 · 2020 · External reference
NIR-II type I photosensitizer for efficient cancer therapy through synergistic ferroptosis/pyroptosis induction and mitophagy inhibition
10.1002/adhm.202501346 · 2025 · External reference
Defining PANoptosis: biochemical and mechanistic evaluation of innate immune cell death activation
10.1002/cpz1.1112 · 2024 · External reference
Autophagy blockage enhancing photothermal and chemodynamic synergistic therapy based on HCQ/CuS nanoplatform
10.1002/adhm.202402367 · 2024 · External reference
Engineering mitochondrial uncoupler synergistic photodynamic nanoplatform to harness immunostimulatory pro-death autophagy/mitophagy
10.1016/j.biomaterials.2022.121796 · 2022 · External reference
Lipid nanoparticular codelivery system for enhanced antitumor effects by ferroptosis-apoptosis synergistic with programmed cell death-ligand 1 downregulation
10.1021/acsnano.4c04901 · 2024 · External reference
A photo-activated thermoelectric catalyst for Ferroptosis-/Pyroptosis-Boosted tumor nanotherapy
10.1002/adhm.202300699 · 2023 · External reference
Nanoparticles synergize ferroptosis and cuproptosis to potentiate cancer immunotherapy
2024 · External reference
Ultrasmall enzyodynamic PANoptosis nano-inducers for ultrasound-amplified hepatocellular carcinoma therapy and lung metastasis inhibition
10.1002/adma.202409618 · 2024 · External reference
Mitochondria-associated ER stress evokes immunogenic cell death through the ROS-PERK-eIF2α pathway under PTT/CDT combined therapy
10.1016/j.actbio.2023.02.011 · 2023 · External reference
Synergistic STING activation and oxidative cascades-induced ferroptosis drive tumor microenvironment remodeling by engineered manganese nanoreactors
2026 · External reference
The role of ROS in tumor infiltrating immune cells and cancer immunotherapy
10.1016/j.metabol.2023.155747 · 2024 · External reference
Self-immolative polymer-based immunogenic cell death inducer for regulation of redox homeostasis
10.1016/j.biomaterials.2023.122064 · 2023 · External reference
Multimodal cascade-amplified phototheranostics for enhanced anti-tumor immunity
2026 · External reference
Tumor microenvironment-responsive engineered hybrid nanomedicine for photodynamic-immunotherapy via multi-pronged amplification of reactive oxygen species
10.1038/s41467-024-55658-0 · 2025 · External reference
Multimodal lung cancer theranostics via manganese phosphate/quercetin particle
10.1186/s12943-025-02242-9 · 2025 · External reference
One-step symbiosis of bimetallic peroxides nanoparticles to induce ferroptosis/cuproptosis and activate cGAS-STING pathway for enhanced tumor immunotherapy
2025 · External reference
Oxygen-vacancy MoO3-x nanodots induce immunogenic cell death and STING activation for synergistic cancer immunotherapy
2025 · External reference
NO-Enhanced sonodynamic nanovesicles with Co-Stimulatory molecule self-presentation for multidimensional tumor immunotherapy
2025 · External reference
A biomimetic nanomedicine for remodeling the immune microenvironment to potentiating anti-tumor therapy
10.1002/adhm.202501457 · 2025 · External reference
PhotoPyro-Induced cGAS-STING pathway activation enhanced anti-melanoma immunotherapy via a manganese-coordinated nanomedicine
2024 · External reference
Ultra-small Janus nanoparticle-induced activation of ferroptosis for synergistic tumor immunotherapy
10.1016/j.actbio.2024.04.032 · 2024 · External reference
An ultrasound-activated nanoplatform remodels tumor microenvironment through diverse cell death induction for improved immunotherapy
10.1016/j.jconrel.2024.05.001 · 2024 · External reference
Photothermal Fe3O4 nanoparticles induced immunogenic ferroptosis for synergistic colorectal cancer therapy
10.1186/s12951-024-02909-3 · 2024 · External reference
Targeted positron emission tomography-tracked biomimetic codelivery synergistically amplifies ferroptosis and pyroptosis for inducing lung cancer regression and Anti-PD-L1 immunotherapy efficacy
10.1021/acsnano.4c11278 · 2024 · External reference
Manganese-enriched zinc peroxide functional nanoparticles for potentiating cancer immunotherapy
10.1021/acs.nanolett.3c02941 · 2023 · External reference
Laser-activated nanoparticles rewire tumor microenvironment enhancing PD-1 blockade and T cell response in cholangiocarcinoma
2025 · External reference
Intra-tumoral hypoxia promotes CD8+ T cell dysfunction via chronic activation of integrated stress response transcription factor ATF4
10.1016/j.immuni.2025.09.003 · 2025 · External reference
Lactate dehydrogenase B facilitates disulfidptosis and exhaustion of tumour-infiltrating CD8+ T cells
10.1038/s41556-025-01673-2 · 2025 · External reference
PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis
10.1016/j.immuni.2024.08.003 · 2024 · External reference
Bioinspired nanoplatform potentiates sonodynamic immunotherapy by remodeling the antioxidant tumor microenvironment and activating STING pathway
10.7150/thno.129765 · 2026 · External reference
Natural killer cell nano-engagers drive ferroptosis-immunomodulation synergy via inhibition of the Interleukin-6-JAK2-STAT3 Axis
2026 · External reference
A multifunctional Fe-EGCG@RSL3 nanomedicine synergizes ferroptosis induction and tumor microenvironment remodeling for enhanced bladder cancer immunotherapy
10.34133/research.0735 · 2025 · External reference
Dual STING activation and CD47/SIRPα blockade via chitooligosaccharide-based nanoparticles to amplify antitumor immunity
2025 · External reference
Novel Photo-STING agonists delivered by erythrocyte efferocytosis-mimicking pattern to repolarize tumor-associated macrophages for boosting anticancer immunotherapy
2024 · External reference
Oxygen-carrying nanoplatform to reprogram tumor immunosuppressive microenvironment and enhance photothermal-immunotherapy
2023 · External reference
ROS scavenging nanozyme modulates immunosuppression for sensitized cancer immunotherapy
2023 · External reference
Chirality-dependent reprogramming of macrophages by chiral nanozymes
2023 · External reference
Multifunctional redox-responsive nanoplatform with dual activation of macrophages and T cells for antitumor immunotherapy
10.1021/acsnano.2c12498 · 2023 · External reference
Biomimetic inducer enabled dual ferroptosis of tumor and M2-type macrophages for enhanced tumor immunotherapy
10.1016/j.biomaterials.2023.122386 · 2023 · External reference
Hypoxic glioblastoma-cell-derived extracellular vesicles impair cGAS-STING activity in macrophages
10.1186/s12964-024-01523-y · 2024 · External reference
Reactive oxygen species-responsive biomimetic nanoplatelets for thrombus-mediated photothermal immunotherapy of tumor
10.1002/anie.202507665 · 2025 · External reference
Stimuli-responsive polymer-dasatinib prodrug to reprogram cancer-associated fibroblasts for boosted immunotherapy
10.1016/j.jconrel.2025.113606 · 2025 · External reference
Bioengineered hybrid dual-targeting nanoparticles reprogram the tumour microenvironment for deep glioblastoma photodynamic therapy
10.1038/s41467-025-63081-2 · 2025 · External reference
Biomimetic nanoimmunotherapy boosts spatiotemporal PANoptosis and reshapes desmoplastic tumor microenvironment
2025 · External reference
Modulating tumor-stromal crosstalk via a redox-responsive nanomedicine for combination tumor therapy
10.1016/j.jconrel.2023.03.015 · 2023 · External reference
Tryptophan 2,3-dioxygenase-positive matrix fibroblasts fuel breast cancer lung metastasis via kynurenine-mediated ferroptosis resistance of metastatic cells and T cell dysfunction
10.1002/cac2.12608 · 2024 · External reference
Cancer-associated fibroblasts reprogram cysteine metabolism to increase tumor resistance to ferroptosis in pancreatic cancer
10.7150/thno.89805 · 2024 · External reference
Nano-armed Limosilactobacillus reuteri for enhanced photo-immunotherapy and microbiota tryptophan metabolism against colorectal cancer
2025 · External reference
Multilayer cascade-response nanoplatforms as metabolic symbiotic disruptors to reprogram the immunosuppressive microenvironment
10.1016/j.jconrel.2025.113797 · 2025 · External reference
Oxamate nanoparticles for enhanced tumor immunotherapy through blocking glycolysis metabolism and inducing pyroptosis
10.1021/acs.nanolett.5c01811 · 2025 · External reference
Multienzymatic hybrid metalloenzymes triggering Cascade reactions-regulated tumor redox homeostasis and immunosuppressive microenvironment for catalytic immunotherapy
10.1021/acsnano.5c06592 · 2025 · External reference
Lactate-modulating nanoreactors facilitate self-amplifying pyroptosis and the cGAS-STING Cascade for potentiated catalytic-immunotherapy
2025 · External reference
Tumor microenvironment-responsive metal-natural polyphenol nanozyme for radiosensitization by interfering glucose metabolism and redox homeostasis
2025 · External reference
Mesoporous multimetallic PdPtBi nanozymes target redox imbalance and glutamine deprivation for immuno-chemodynamic therapy
10.1186/s12951-025-03856-3 · 2025 · External reference
Necroptosis-mediated synergistic photodynamic and glutamine-metabolic therapy enabled by a biomimetic targeting nanosystem for cholangiocarcinoma
2024 · External reference
Lactate/cysteine dual-consuming probiotic-nanomedicine biohybrid system for enhanced cancer chemo-immunotherapy
10.1021/acs.nanolett.4c04938 · 2024 · External reference
Itaconate transporter SLC13A3 impairs tumor immunity via endowing ferroptosis resistance
10.1016/j.ccell.2024.10.010 · 2024 · External reference
Tumor microenvironment-initiated lipid redox cycling for efficient triple-negative breast cancer therapy
2023 · External reference
Reactive oxygen species nanoamplifiers with multi-enzymatic activities for enhanced tumor therapy
10.1039/d3nr00107e · 2023 · External reference
Redox responsive nanosystems for medicine: from reactive species mapping to precision treatment
10.1016/j.addr.2026.115892 · 2026 · External reference
First-in-Human study testing a new radioenhancer using nanoparticles (NBTXR3) activated by radiation therapy in patients with locally advanced soft tissue sarcomas
10.1158/1078-0432.ccr-16-1297 · 2017 · External reference
Phase I dose-escalation study of NBTXR3 activated by intensity-modulated radiation therapy in elderly patients with locally advanced squamous cell carcinoma of the oral cavity or oropharynx
10.1016/j.ejca.2021.01.007 · 2021 · External reference
NBTXR3, a first-in-class radioenhancer hafnium oxide nanoparticle, plus radiotherapy versus radiotherapy alone in patients with locally advanced soft-tissue sarcoma (Act.In.Sarc): a multicentre, phase 2-3, randomised, controlled trial
10.1016/s1470-2045(19)30326-2 · 2019 · External reference
Final safety and health-related quality of LIfe results of the phase 2/3 Act.In.Sarc study with preoperative NBTXR3 plus radiation therapy versus radiation therapy in locally advanced soft-tissue sarcoma
10.1016/j.ijrobp.2022.07.001 · 2022 · External reference
A phase Ib/II trial of PEP503 (NBTXR3, radioenhancer) with radiotherapy and chemotherapy in patients with rectal cancer
10.2217/nnm-2022-0186 · 2023 · External reference
Results of phase Ib/II trial of PEP503 (NBTXR3, radioenhancer) with chemoradiotherapy in patients with rectal cancer
10.1080/17435889.2025.2487411 · 2025 · External reference
Theranostic AGuIX nanoparticles as radiosensitizer: a phase I, dose-escalation study in patients with multiple brain metastases (NANO-RAD trial)
10.1016/j.radonc.2021.04.021 · 2021 · External reference
Clinical transfer of AGuIX®-based radiation treatments for locally advanced cervical cancer: MR quantification and in vitro insights in the NANOCOL clinical trial framework
2023 · External reference
Theragnostic gadolinium-based nanoparticles safely augment X-ray radiation effects in patients with cervical cancer
10.1021/acsnano.3c12537 · 2024 · External reference
A phase 2 multicenter clinical trial of intraoperative molecular imaging of lung cancer with a pH-Activatable nanoprobe
10.1007/s11307-024-01933-x · 2024 · External reference
A pH-Activatable nanoprobe labels diverse histologic subtypes of human lung cancer during resection
10.1007/s11307-023-01853-2 · 2023 · External reference
Detection of residual peritoneal metastases following cytoreductive surgery using pegsitacianine, a pH-Sensitive imaging agent: final results from a phase II study
10.1245/s10434-024-15165-4 · 2024 · External reference
Nanoray-312: phase III study of NBTXR3 + radiotherapy ± cetuximab in elderly, platinum-ineligible locally advanced HNSCC
10.1080/14796694.2025.2496131 · 2025 · External reference
Exploiting metabolic acidosis in solid cancers using a tumor-agnostic pH-activatable nanoprobe for fluorescence-guided surgery
10.1038/s41467-020-16814-4 · 2020 · External reference
First-in-human evidence of multidrug resistance reversal in solid tumors: a cohort analysis of carbon nanoparticles-Fe(II) complex trials
10.1186/s12885-026-16216-7 · 2026 · External reference
Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer
10.1038/bjc.2014.95 · 2014 · External reference
A translational framework to DELIVER nanomedicines to the clinic
10.1038/s41565-024-01754-7 · 2024 · External reference
Clinical cancer nanomedicines
2025 · External reference
Cancer nanomedicine toward clinical translation: obstacles, opportunities, and future prospects
10.1016/j.medj.2022.12.001 · 2023 · External reference
