Research graph
References from Gestational exposure to low-dose PFOA during organogenesis induces embryofetal developmental alterations in rats. Local targets link to admitted publications; unresolved targets remain external evidence.
Perfluoroalkyl and polyfluoroalkyl substances in the environment: terminology, classification, and origins
10.1002/ieam.258 · 2011 · External reference
Risk to human health related to the presence of perfluoroalkyl substances in food
2020 · External reference
Placental transfer and composition of perfluoroalkyl substances (PFASs): a Korean birth panel of parent-infant triads
10.3390/toxics9070168 · 2021 · External reference
Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
10.1016/j.envint.2017.06.007 · 2017 · External reference
The developmental origins of adult disease
10.1080/07315724.2004.10719428 · 2004 · External reference
Developmental origins of health and disease: a paradigm for understanding disease cause and prevention
10.1097/mop.0000000000000191 · 2015 · External reference
EDC-2: The endocrine society's second scientific statement on endocrine-disrupting chemicals
10.1210/er.2015-1010 · 2015 · External reference
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
10.1210/er.2011-1050 · 2012 · External reference
Effects of perfluorooctanoic acid exposure during pregnancy in the mouse
10.1093/toxsci/kfj105 · 2006 · External reference
Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: a critical review of recent literature
10.1016/j.envres.2012.03.007 · 2012 · External reference
Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR
10.1093/toxsci/kfn025 · 2008 · External reference
Developmental neurotoxicity of industrial chemicals
10.1016/s0140-6736(06)69665-7 · 2006 · External reference
Genetic toxicities of human teratogens
1997 · External reference
Effects of benzo(a)pyrene at environmentally relevant doses on embryo-fetal development in rats
10.1002/tox.23085 · 2021 · External reference
Guideline levels for PFOA and PFOS in drinking water: the role of scientific uncertainty, risk assessment decisions, and social factors
10.1038/s41370-018-0099-9 · 2019 · External reference
Unresolved reference
External reference
Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha
10.1093/toxsci/kfm110 · 2007 · External reference
Unresolved reference
External reference
Teratogenic effect of usnic acid from cladonia substellata vainio during organogenesis
10.1155/2017/5948936 · 2017 · External reference
10.1787/9789264070820-en
10.1787/9789264070820-en · External reference
Unresolved reference
External reference
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
2020 · External reference
utero and lactational exposure to fipronil in female rats: pregnancy outcomes and sexual development
10.1080/15287394.2016.1149132 · 2016 · External reference
Modulation of lipid metabolism by n-3 polyunsaturated fatty acids in gestational diabetic rats and their macrosomic offspring
10.1042/cs20050028 · 2005 · External reference
Unresolved reference
External reference
Methods for administering agents and detecting malformations in experimental animals
1965 · External reference
A rapid method for detecting malformations in rat fetuses
10.1002/jmor.1051270303 · 1969 · External reference
Test methods for assessing female reproductive and developmental toxicology
1994 · External reference
Effects of the polysaccharide beta-glucan on clastogenicity and teratogenicity caused by acute exposure to cyclophosphamide in mice
10.1016/j.yrtph.2008.12.007 · 2009 · External reference
Refinements in rapid clearing technic in the KOH–alizarin red S method for fetal bone
1964 · External reference
The extent of fetal ossification as an index of delayed development in teratogenic studies on the rat
10.1002/tera.1420200208 · 1979 · External reference
Skeletal Examination
1986 · External reference
Endocrine disrupting properties of perfluorooctanoic acid
10.1016/j.jsbmb.2011.03.011 · 2011 · External reference
Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)
10.1289/ehp6233 · 2020 · External reference
Sex-specific placental responses in fetal development
10.1210/en.2015-1227 · 2015 · External reference
Sexual dimorphism in environmental epigenetic programming
10.1016/j.mce.2009.02.015 · 2009 · External reference
Making or breaking the heart: from lineage determination to morphogenesis
10.1016/j.cell.2006.09.003 · 2006 · External reference
The Navigation Guide - evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth
10.1289/ehp.1307893 · 2014 · External reference
Perfluoroalkyl Acids in Maternal Serum and Indices of Fetal Growth: The Aarhus Birth Cohort
10.1289/ehp.1510046 · 2016 · External reference
Evaluating maternal exposure to an environmental per and polyfluoroalkyl substances (PFAS) mixture during pregnancy: adverse maternal and fetoplacental effects in a New Zealand White (NZW) rabbit model
2022 · External reference
Maternal exposure to perfluorobutane sulfonate (PFBS) during pregnancy: evidence of adverse maternal and fetoplacental effects in New Zealand White (NZW) rabbits
10.1093/toxsci/kfac126 · 2023 · External reference
Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease
10.1016/j.ajog.2017.12.012 · 2018 · External reference
Interpretation of skeletal variations for human risk assessment: delayed ossification and wavy ribs
10.1002/bdrb.20133 · 2007 · External reference
Skeletal variations and their role in developmental toxicity studies
2011 · External reference
Segmental patterning of the vertebrate embryonic axis
10.1038/nrg2320 · 2008 · External reference
Relationships between fetal body weight of Wistar rats at term and the extent of skeletal ossification
10.1590/s0100-879x2005000400010 · 2005 · External reference
Bone development in laboratory mammals used in developmental toxicity studies
10.1002/bdr2.1350 · 2018 · External reference
Adverse Maternal, Fetal, and Postnatal Effects of Hexafluoropropylene Oxide Dimer Acid (GenX) from Oral Gestational Exposure in Sprague-Dawley Rats
10.1289/ehp4372 · 2019 · External reference
Placental Lesions in CD-1 Mouse Placenta Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)
10.1177/01926233261439119 · 2026 · External reference
Perfluorooctanoate exposure and major birth defects
10.1016/j.reprotox.2014.04.006 · 2014 · External reference
Environmental exposure to per- and polyfluoroalkyl substances and childhood congenital heart disease: a mixed analysis
10.3389/fpubh.2025.1657168 · 2025 · External reference
Concentrations of perfluoroalkyl substances (PFASs) in human embryonic and fetal organs from first, second, and third trimester pregnancies
10.1016/j.envint.2019.01.010 · 2019 · External reference
Half-life of serum elimination of perfluorooctanesulfonate,perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers
10.1289/ehp.10009 · 2007 · External reference
Perfluoroalkyl acids: a review of monitoring and toxicological findings
10.1093/toxsci/kfm128 · 2007 · External reference
Sex hormone-regulated renal transport of perfluorooctanoic acid
10.1016/s0009-2797(02)00006-6 · 2002 · External reference
Complementing the genome with an "exposome": the outstanding challenge of environmental exposure measurement in molecular epidemiology
2005 · External reference
The exposome and health: where chemistry meets biology
10.1126/science.aay3164 · 2020 · External reference
The one health concept: 10 years old and a long road ahead
10.3389/fvets.2018.00014 · 2018 · External reference
Bone development in laboratory mammals used in developmental toxicity studies
10.1002/bdr2.1350 · ExternalCitation · doi-reference
Interpretation of skeletal variations for human risk assessment: delayed ossification and wavy ribs
10.1002/bdrb.20133 · ExternalCitation · doi-reference
Perfluoroalkyl and polyfluoroalkyl substances in the environment: terminology, classification, and origins
10.1002/ieam.258 · ExternalCitation · doi-reference
A rapid method for detecting malformations in rat fetuses
10.1002/jmor.1051270303 · ExternalCitation · doi-reference
The extent of fetal ossification as an index of delayed development in teratogenic studies on the rat
10.1002/tera.1420200208 · ExternalCitation · doi-reference
Effects of benzo(a)pyrene at environmentally relevant doses on embryo-fetal development in rats
10.1002/tox.23085 · ExternalCitation · doi-reference
Long-term cardiovascular consequences of fetal growth restriction: biology, clinical implications, and opportunities for prevention of adult disease
10.1016/j.ajog.2017.12.012 · ExternalCitation · doi-reference
Making or breaking the heart: from lineage determination to morphogenesis
10.1016/j.cell.2006.09.003 · ExternalCitation · doi-reference
Per- and polyfluoroalkyl substances in human serum and urine samples from a residentially exposed community
10.1016/j.envint.2017.06.007 · ExternalCitation · doi-reference
Concentrations of perfluoroalkyl substances (PFASs) in human embryonic and fetal organs from first, second, and third trimester pregnancies
10.1016/j.envint.2019.01.010 · ExternalCitation · doi-reference
Perfluorooctanoic acid (PFOA), an emerging drinking water contaminant: a critical review of recent literature
10.1016/j.envres.2012.03.007 · ExternalCitation · doi-reference
Endocrine disrupting properties of perfluorooctanoic acid
10.1016/j.jsbmb.2011.03.011 · ExternalCitation · doi-reference
Sexual dimorphism in environmental epigenetic programming
10.1016/j.mce.2009.02.015 · ExternalCitation · doi-reference
Perfluorooctanoate exposure and major birth defects
10.1016/j.reprotox.2014.04.006 · ExternalCitation · doi-reference
Effects of the polysaccharide beta-glucan on clastogenicity and teratogenicity caused by acute exposure to cyclophosphamide in mice
10.1016/j.yrtph.2008.12.007 · ExternalCitation · doi-reference
Sex hormone-regulated renal transport of perfluorooctanoic acid
10.1016/s0009-2797(02)00006-6 · ExternalCitation · doi-reference
Developmental neurotoxicity of industrial chemicals
10.1016/s0140-6736(06)69665-7 · ExternalCitation · doi-reference
Segmental patterning of the vertebrate embryonic axis
10.1038/nrg2320 · ExternalCitation · doi-reference
Guideline levels for PFOA and PFOS in drinking water: the role of scientific uncertainty, risk assessment decisions, and social factors
10.1038/s41370-018-0099-9 · ExternalCitation · doi-reference
Modulation of lipid metabolism by n-3 polyunsaturated fatty acids in gestational diabetic rats and their macrosomic offspring
10.1042/cs20050028 · ExternalCitation · doi-reference
The developmental origins of adult disease
10.1080/07315724.2004.10719428 · ExternalCitation · doi-reference
utero and lactational exposure to fipronil in female rats: pregnancy outcomes and sexual development
10.1080/15287394.2016.1149132 · ExternalCitation · doi-reference
Maternal exposure to perfluorobutane sulfonate (PFBS) during pregnancy: evidence of adverse maternal and fetoplacental effects in New Zealand White (NZW) rabbits
10.1093/toxsci/kfac126 · ExternalCitation · doi-reference
Effects of perfluorooctanoic acid exposure during pregnancy in the mouse
10.1093/toxsci/kfj105 · ExternalCitation · doi-reference
Perfluorooctanoic acid induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha
10.1093/toxsci/kfm110 · ExternalCitation · doi-reference
Perfluoroalkyl acids: a review of monitoring and toxicological findings
10.1093/toxsci/kfm128 · ExternalCitation · doi-reference
Toxicogenomic dissection of the perfluorooctanoic acid transcript profile in mouse liver: evidence for the involvement of nuclear receptors PPAR alpha and CAR
10.1093/toxsci/kfn025 · ExternalCitation · doi-reference
Developmental origins of health and disease: a paradigm for understanding disease cause and prevention
10.1097/mop.0000000000000191 · ExternalCitation · doi-reference
The exposome and health: where chemistry meets biology
10.1126/science.aay3164 · ExternalCitation · doi-reference
Teratogenic effect of usnic acid from cladonia substellata vainio during organogenesis
10.1155/2017/5948936 · ExternalCitation · doi-reference
Placental Lesions in CD-1 Mouse Placenta Following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)
10.1177/01926233261439119 · ExternalCitation · doi-reference
Sex-specific placental responses in fetal development
10.1210/en.2015-1227 · ExternalCitation · doi-reference
Hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses
10.1210/er.2011-1050 · ExternalCitation · doi-reference
EDC-2: The endocrine society's second scientific statement on endocrine-disrupting chemicals
10.1210/er.2015-1010 · ExternalCitation · doi-reference
Half-life of serum elimination of perfluorooctanesulfonate,perfluorohexanesulfonate, and perfluorooctanoate in retired fluorochemical production workers
10.1289/ehp.10009 · ExternalCitation · doi-reference
The Navigation Guide - evidence-based medicine meets environmental health: systematic review of human evidence for PFOA effects on fetal growth
10.1289/ehp.1307893 · ExternalCitation · doi-reference
Perfluoroalkyl Acids in Maternal Serum and Indices of Fetal Growth: The Aarhus Birth Cohort
10.1289/ehp.1510046 · ExternalCitation · doi-reference
Adverse Maternal, Fetal, and Postnatal Effects of Hexafluoropropylene Oxide Dimer Acid (GenX) from Oral Gestational Exposure in Sprague-Dawley Rats
10.1289/ehp4372 · ExternalCitation · doi-reference
Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX)
10.1289/ehp6233 · ExternalCitation · doi-reference
Relationships between fetal body weight of Wistar rats at term and the extent of skeletal ossification
10.1590/s0100-879x2005000400010 · ExternalCitation · doi-reference
10.1787/9789264070820-en
10.1787/9789264070820-en · ExternalCitation · doi-reference
Environmental exposure to per- and polyfluoroalkyl substances and childhood congenital heart disease: a mixed analysis
10.3389/fpubh.2025.1657168 · ExternalCitation · doi-reference
The one health concept: 10 years old and a long road ahead
10.3389/fvets.2018.00014 · ExternalCitation · doi-reference
Placental transfer and composition of perfluoroalkyl substances (PFASs): a Korean birth panel of parent-infant triads
10.3390/toxics9070168 · ExternalCitation · doi-reference
