Research graph
References from Frailty-specific dose-response relationships between physical activity and all-cause mortality: Longitudinal observational study combining accelerometry data. Local targets link to admitted publications; unresolved targets remain external evidence.
A brief clinical instrument to classify frailty in elderly people
10.1016/s0140-6736(98)04402-x · 1999 · External reference
Targeting strategies: an overview of criteria and outcomes
10.1111/j.1532-5415.1991.tb05930.x · 1991 · External reference
Unstable disability and the fluctuations of frailty
10.1093/ageing/26.4.315 · 1997 · External reference
Loss of ‘complexity’ and aging: potential applications of fractals and chaos theory to senescence
10.1001/jama.1992.03480130122036 · 1992 · External reference
Frailty in elderly people
10.1016/s0140-6736(12)62167-9 · 2013 · External reference
Prevalence and correlates of frailty among community-dwelling older men and women: findings from the Hertfordshire Cohort Study
10.1093/ageing/afp204 · 2010 · External reference
Frailty is associated with impairment of vaccine-induced antibody response and increase in post-vaccination influenza infection in community-dwelling older adults
10.1016/j.vaccine.2011.04.077 · 2011 · External reference
World Health Organization 2020 guidelines on physical activity and sedentary behaviour
10.1136/bjsports-2020-102955 · 2020 · External reference
Fulfillment of physical activity guidelines in the general population and frailty status in the elderly population
10.1007/s00508-018-1408-y · 2019 · External reference
Physical activity and association between frailty and all-cause and cardiovascular mortality in older adults: population-based prospective cohort study
10.1111/jgs.15542 · 2018 · External reference
Accelerometer-measured physical activity, frailty, and all-cause mortality and life expectancy among middle-aged and older adults: a UK Biobank longitudinal study
10.1186/s12916-025-03960-z · 2025 · External reference
The longitudinal associations between change in physical activity and cognitive functioning in older adults with chronic illness (es)
10.1186/s12877-021-02429-x · 2021 · External reference
Accelerometer-derived physical activity and mortality in individuals with type 2 diabetes
10.1038/s41467-024-49542-0 · 2024 · External reference
Comparison of sociodemographic and health-related characteristics of UK biobank participants with those of the general population
10.1093/aje/kwx246 · 2017 · External reference
Wearable-device-measured physical activity and future health risk
10.1038/s41591-020-1012-3 · 2020 · External reference
Association between device-measured physical activity and incident heart failure: a prospective cohort study of 94 739 UK biobank participants
10.1161/circulationaha.122.059663 · 2022 · External reference
Accelerometer-measured intensity-specific physical activity, genetic risk and incident type 2 diabetes: a prospective cohort study
10.1136/bjsports-2022-106653 · 2023 · External reference
Frailty in older adults: evidence for a phenotype
10.1093/gerona/56.3.m146 · 2001 · External reference
Risk factors and protective factors associated with incident or increase of frailty among community-dwelling older adults: a systematic review of longitudinal studies
10.1371/journal.pone.0178383 · 2017 · External reference
Association of habitual alcohol intake with risk of cardiovascular disease
10.1001/jamanetworkopen.2022.3849 · 2022 · External reference
Frailty: implications for clinical practice and public health
10.1016/s0140-6736(19)31786-6 · 2019 · External reference
Epidemiology of multimorbidity and implications for health care, research, and medical education: a cross-sectional study
10.1016/s0140-6736(12)60240-2 · 2012 · External reference
Unresolved reference
2015 · External reference
Dose–response association between moderate to vigorous physical activity and incident morbidity and mortality for individuals with a different cardiovascular health status: a cohort study among 142, 493 adults from the Netherlands
10.1371/journal.pmed.1003845 · 2021 · External reference
Association of accelerometer-derived physical activity with all-cause and cause-specific mortality among individuals with cardiovascular diseases: a prospective cohort study
10.1093/eurjpc/zwae248 · 2025 · External reference
Long-term leisure-time physical activity intensity and all-cause and cause-specific mortality: a prospective cohort of US adults
10.1161/circulationaha.121.058162 · 2022 · External reference
Associations of timing of physical activity with all-cause and cause-specific mortality in a prospective cohort study
10.1038/s41467-023-36546-5 · 2023 · External reference
Neuroprotective mechanisms of exercise and the importance of fitness for healthy brain ageing
10.1016/s0140-6736(25)00184-9 · 2025 · External reference
A century of exercise physiology: key concepts on coupling respiratory oxygen flow to muscle energy demand during exercise
10.1007/s00421-022-04901-x · 2022 · External reference
Sedentary behavior, exercise, and cardiovascular health
10.1161/circresaha.118.312669 · 2019 · External reference
Exercise-induced increase in muscle insulin sensitivity
10.1152/japplphysiol.00123.2005 · 2005 · External reference
Analysis of the dose-response effects of physical activity on cardiocerebrovascular and all-cause mortality in hypertension
2022 · External reference
Dose-response effects of physical activity on all-cause mortality and major cardiorenal outcomes in chronic kidney disease
10.1093/eurjpc/zwaa162 · 2022 · External reference
Dose–response relationship between physical activity and mortality in adults with noncommunicable diseases: a systematic review and meta-analysis of prospective observational studies
10.1186/s12966-020-01007-5 · 2020 · External reference
Minimum amount of physical activity for reduced mortality and extended life expectancy: a prospective cohort study
10.1016/s0140-6736(11)60749-6 · 2011 · External reference
Light and moderate intensity physical activity are associated with better ambulation, quality of life, and vascular measurements in patients with claudication
10.1016/j.jvs.2021.12.071 · 2022 · External reference
Joint association between accelerometry-measured daily combination of time spent in physical activity, sedentary behaviour and sleep and all-cause mortality: a pooled analysis of six prospective cohorts using compositional analysis
10.1136/bjsports-2020-102345 · 2021 · External reference
Reproducibility of accelerometer-assessed physical activity and sedentary time
10.1016/j.amepre.2016.11.010 · 2017 · External reference
Reliability of accelerometer-determined physical activity and sedentary behavior in school-aged children: a 12-country study
10.1038/ijosup.2015.16 · 2015 · External reference
