Research graph
References from Advances in Prognostic Assessment of Idiopathic Pulmonary Fibrosis: From Clinical-Physiological Parameters and Molecular Biomarkers to Multimodal Models. Local targets link to admitted publications; unresolved targets remain external evidence.
Idiopathic Pulmonary Fibrosis (an Update) and Progressive Pulmonary Fibrosis in Adults: An Official ATS/ERS/JRS/ALAT Clinical Practice Guideline
10.1164/rccm.202202-0399st · 2022 · External reference
Changes in lung function and exercise capacity are strong predictors of mortality in patients with IPF receiving antifibrotic therapy
2025 · External reference
Changes in Lung Function and Mortality Risk in Patients With Idiopathic Pulmonary Fibrosis
10.1016/j.chest.2025.02.018 · 2025 · External reference
Idiopathic pulmonary fibrosis: a composite physiologic index derived from disease extent observed by computed tomography
10.1164/rccm.2111053 · 2003 · External reference
CT staging and monitoring of fibrotic interstitial lung diseases in clinical practice and treatment trials: a position paper from the Fleischner Society
10.1016/s2213-2600(15)00096-x · 2015 · External reference
Idiopathic pulmonary fibrosis: clinically meaningful primary endpoints in phase 3 clinical trials
10.1164/rccm.201201-0006pp · 2012 · External reference
6-Minute walk distance is an independent predictor of mortality in patients with idiopathic pulmonary fibrosis
10.1183/09031936.00131813 · 2014 · External reference
Development and validation of a predictive 6-min walk score in patients with idiopathic pulmonary fibrosis
10.1183/13993003.02565-2024 · 2025 · External reference
Imaging Patterns Are Associated with Interstitial Lung Abnormality Progression and Mortality
10.1164/rccm.201809-1652oc · 2019 · External reference
Upper-lobe subpleural irregularity predicts progression and mortality in idiopathic pulmonary fibrosis
10.1016/j.rmed.2025.108488 · 2025 · External reference
CT Honeycombing and Traction Bronchiectasis Extent Independently Predict Survival across Fibrotic Interstitial Lung Disease Subtypes
10.1148/radiol.241001 · 2025 · External reference
Clinical significance of pulmonary hypertension in interstitial lung disease: A consensus statement from the Pulmonary Vascular Research Institute's innovative drug development initiative-Group 3 pulmonary hypertension
10.1002/pul2.12127 · 2022 · External reference
Pulmonary Hypertension Drives Prognosis in Idiopathic Pulmonary Fibrosis: Insights from the European IPF Registry
10.3390/jcm14207352 · 2025 · External reference
Imaging of Pulmonary Hypertension: Pictorial Essay
10.1016/j.chest.2019.04.003 · 2019 · External reference
Pulmonary hypertension in COPD: results from the ASPIRE registry
10.1183/09031936.00079512 · 2013 · External reference
Evaluation of the CT imaging findings in patients newly diagnosed with chronic thromboembolic pulmonary hypertension
10.1371/journal.pone.0201468 · 2018 · External reference
A clinical, radiographic, and physiologic scoring system for the longitudinal assessment of patients with idiopathic pulmonary fibrosis
10.1164/arrd.1986.133.1.97 · 1986 · External reference
Predicting survival in idiopathic pulmonary fibrosis: scoring system and survival model
10.1164/ajrccm.164.7.2003140 · 2001 · External reference
A multidimensional index and staging system for idiopathic pulmonary fibrosis
10.7326/0003-4819-156-10-201205150-00004 · 2012 · External reference
Comparison of CPI and GAP models in patients with idiopathic pulmonary fibrosis: a nationwide cohort study
10.1038/s41598-018-23073-3 · 2018 · External reference
Derivation and validation of a simple multidimensional index incorporating exercise capacity parameters for survival prediction in idiopathic pulmonary fibrosis
10.1136/thoraxjnl-2021-218440 · 2023 · External reference
External validation and longitudinal application of the DO-GAP index to individualise survival prediction in idiopathic pulmonary fibrosis
10.1183/23120541.00124-2023 · 2023 · External reference
Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality
10.1164/ajrccm.164.6.2001056 · 2001 · External reference
Artificial intelligence identifies inflammation and confirms fibroblast foci as prognostic tissue biomarkers in idiopathic pulmonary fibrosis
10.1016/j.humpath.2020.10.008 · 2021 · External reference
Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis
10.1378/chest.07-1948 · 2008 · External reference
Quantitative CT Analysis of Diffuse Lung Disease
10.1148/rg.2020190099 · 2020 · External reference
Quantitative CT of Interstitial Lung Disease
10.1053/j.ro.2018.12.007 · 2019 · External reference
Serial automated quantitative CT analysis in idiopathic pulmonary fibrosis: functional correlations and comparison with changes in visual CT scores
10.1007/s00330-017-5053-z · 2018 · External reference
Correlation of Lung Texture Analysis by Computer-Aided Lung Informatics for Pathology Evaluation and Rating (CALIPER) With High-Resolution Computed Tomography and Lung Function in Fibrosing Interstitial Lung Diseases
2026 · External reference
Novel Artificial Intelligence-based Technology for Chest Computed Tomography Analysis of Idiopathic Pulmonary Fibrosis
10.1513/annalsats.202101-044oc · 2022 · External reference
Deep Learning-based Outcome Prediction in Progressive Fibrotic Lung Disease Using High-Resolution Computed Tomography
10.1164/rccm.202112-2684oc · 2022 · External reference
Exhaled breath analysis in interstitial lung disease
10.1097/mcp.0000000000000978 · 2023 · External reference
Exhaled volatile organiccompounds in idiopathic pulmonary fibrosisand disease progression
2020 · External reference
Biomarkers in idiopathic pulmonary fibrosis: Current insight and future direction
10.1016/j.pccm.2024.04.003 · 2024 · External reference
The use of exhaled air analysis in discriminating interstitial lung diseases: a pilot study
10.1186/s12931-021-01923-5 · 2022 · External reference
Familial Pulmonary Fibrosis: Genetic Features and Clinical Implications
10.1016/j.chest.2021.06.037 · 2021 · External reference
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
10.1126/sciadv.aba1983 · 2020 · External reference
Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants
10.1016/j.chest.2019.03.030 · 2019 · External reference
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study
10.1016/s2213-2600(22)00251-x · 2023 · External reference
Telomere length across different UIP fibrotic-Interstitial Lung Diseases: a prospective Greek case-control study
10.1016/j.pulmoe.2020.11.005 · 2022 · External reference
Telomere Length and Use of Immunosuppressive Medications in Idiopathic Pulmonary Fibrosis
10.1164/rccm.201809-1646oc · 2019 · External reference
Molecular and Genetic Biomarkers in Idiopathic Pulmonary Fibrosis: Where Are We Now
10.3390/biomedicines11102796 · 2023 · External reference
Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
10.1016/s2213-2600(13)70045-6 · 2013 · External reference
The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis
10.1164/rccm.201304-0760oc · 2013 · External reference
Pharmacogenetics and interstitial lung disease
10.1097/mcp.0000000000000289 · 2016 · External reference
Integrated plasma proteomics and lung transcriptomics reveal novel biomarkers in idiopathic pulmonary fibrosis
10.1186/s12931-021-01860-3 · 2021 · External reference
Review: Serum biomarkers in idiopathic pulmonary fibrosis and systemic sclerosis associated interstitial lung disease - frontiers and horizons
10.1016/j.pharmthera.2019.05.014 · 2019 · External reference
KL-6 as an Immunological Biomarker Predicts the Severity, Progression, Acute Exacerbation, and Poor Outcomes of Interstitial Lung Disease: A Systematic Review and Meta-Analysis
10.3389/fimmu.2021.745233 · 2021 · External reference
Serum KL-6 as a biomarker to predict progression at one year in interstitial lung disease
10.1038/s41598-025-22483-4 · 2025 · External reference
Baseline plasma KL-6 level predicts adverse outcomes in patients with idiopathic pulmonary fibrosis receiving nintedanib: a retrospective real-world cohort study
10.1186/s12890-021-01530-6 · 2021 · External reference
SP-A and SP-D: Dual Functioning Immune Molecules With Antiviral and Immunomodulatory Properties
2020 · External reference
Serum surfactant protein D as a significant biomarker for predicting occurrence, progression, acute exacerbation, and mortality in interstitial lung disease: a systematic review and meta-analysis
2025 · External reference
Serum Biomarkers of Pulmonary Damage and Risk for Progression of Rheumatoid Arthritis-Associated Interstitial Lung Disease
2025 · External reference
Elevation of surfactant protein A in plasma and sputum in cigarette smokers
10.1183/09031936.00110510 · 2011 · External reference
Molecular Biomarkers in Idiopathic Pulmonary Fibrosis: State of the Art and Future Directions
10.3390/ijms22126255 · 2021 · External reference
Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial
10.1016/s2213-2600(16)30421-0 · 2017 · External reference
A systematic review of blood biomarkers with individual participant data meta-analysis of matrix metalloproteinase-7 in idiopathic pulmonary fibrosis
10.1183/13993003.01612-2021 · 2022 · External reference
TIMP-1 and its potential diagnostic and prognostic value in pulmonary diseases
10.1016/j.pccm.2023.05.002 · 2023 · External reference
Expression of HSP47 in usual interstitial pneumonia and nonspecific interstitial pneumonia
10.1186/1465-9921-6-57 · 2005 · External reference
Circulating lung biomarkers in idiopathic lung fibrosis and interstitial lung diseases associated with connective tissue diseases: Where do we stand
10.1016/j.semarthrit.2020.01.006 · 2020 · External reference
Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis
10.1164/rccm.200808-1201oc · 2009 · External reference
S100A12 as Biomarker of Disease Severity and Prognosis in Patients With Idiopathic Pulmonary Fibrosis
2022 · External reference
ICAM-1: A master regulator of cellular responses in inflammation, injury resolution, and tumorigenesis
10.1002/jlb.2mr0220-549r · 2020 · External reference
Biomarker signatures for progressive idiopathic pulmonary fibrosis
10.1183/13993003.01181-2021 · 2022 · External reference
Endothelin-1 as a Biomarker of Idiopathic Pulmonary Fibrosis and Interstitial Lung Disease Associated with Autoimmune Diseases
10.3390/ijms24021275 · 2023 · External reference
Associations of High Attenuation Area-Related Proteomic Biomarkers with Fibrotic or Subpleural Interstitial Lung Abnormalities
10.1164/rccm.202503-0610oc · 2025 · External reference
Autophagy, Apoptosis, the Unfolded Protein Response, and Lung Function in Idiopathic Pulmonary Fibrosis
10.3390/cells10071642 · 2021 · External reference
Autophagy and the unfolded protein response promote profibrotic effects of TGF-β(1) in human lung fibroblasts
10.1152/ajplung.00372.2017 · 2018 · External reference
Endoplasmic reticulum stress in the pathogenesis of fibrotic disease
10.1172/jci93560 · 2018 · External reference
Genetic-informed proteome-wide scan reveals potential causal plasma proteins for idiopathic pulmonary fibrosis
10.1136/thorax-2024-221398 · 2024 · External reference
Identifying potential biomarkers of idiopathic pulmonary fibrosis through machine learning analysis
2023 · External reference
Multi-modal machine learning classifier for idiopathic pulmonary fibrosis predicts mortality in interstitial lung diseases
10.1016/j.resinv.2025.07.021 · 2025 · External reference
Developing and Validation of a Multimodal-Based Machine Learning Model for Diagnosis of Usual Interstitial Pneumonia: A Prospective Multicenter Study
10.1016/j.chest.2025.08.034 · 2026 · External reference
Radiomics-Based Artificial Intelligence and Machine Learning Approach for the Diagnosis and Prognosis of Idiopathic Pulmonary Fibrosis: A Systematic Review
2025 · External reference
