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References from Intermittent low-efficiency hemodiafiltration causes a marked decrease in ampicillin and sulbactam plasma concentration in dogs with oliguric acute kidney injury. Local targets link to admitted publications; unresolved targets remain external evidence.
Overview and evaluation of existing guidelines for rational antimicrobial use in small-animal veterinary practice in Europe
10.3390/antibiotics10040409 · 2021 · External reference
Pharmacokinetics of ampicillin (2.0 grams) and sulbactam (1.0 gram) coadministered to subjects with normal and abnormal renal function and with end-stage renal disease on hemodialysis
10.1128/aac.33.9.1470 · 1989 · External reference
Unresolved reference
2011 · External reference
Comparative pharmacokinetics and tissue penetration of sulbactam and ampicillin after concurrent intravenous administration
10.1128/aac.21.4.565 · 1982 · External reference
Acute kidney injury management using intermittent low efficiency haemodiafiltration in a critical care unit: 39 dogs (2012–2015)
10.1186/s13028-019-0452-6 · 2019 · External reference
Unresolved reference
2024 · External reference
Fluid management in critically ill patients: the role of extravascular lung water, abdominal hypertension, capillary leak, and fluid balance
10.1186/2110-5820-2-s1-s1 · 2012 · External reference
Pharmacokinetics of sulbactam/ampicillin in humans: a review
10.1093/clinids/8.supplement_5.503 · 1986 · External reference
Unresolved reference
2022 · External reference
Pharmacokinetics of cefoperazone/sulbactam in critically ill patients receiving continuous venovenous hemofiltration
10.1007/s00228-016-2045-x · 2016 · External reference
The acute patient physiologic and laboratory evaluation (APPLE) score: a severity of illness stratification system for hospitalized dogs
10.1111/j.1939-1676.2010.0552.x · 2010 · External reference
The impact of variation in renal replacement therapy settings on piperacillin, meropenem, and vancomycin drug clearance in the critically ill: an analysis of published literature and dosing regimens*
10.1097/ccm.0000000000000317 · 2014 · External reference
Dialysate potassium, serum potassium, mortality, and arrhythmia events in hemodialysis: results from the dialysis outcomes and practice patterns study (DOPPS)
10.1053/j.ajkd.2016.09.015 · 2017 · External reference
Acute kidney injury in severe sepsis: pathophysiology, diagnosis, and treatment recommendations
10.1111/vec.12297 · 2015 · External reference
Pharmacokinetic effects of altered plasma protein binding of drugs in renal disease
10.1007/bf03189651 · 1984 · External reference
Pharmacokinetics of ampicillin/sulbactam in critically ill patients with acute kidney injury undergoing extended dialysis
10.2215/cjn.05690611 · 2012 · External reference
Focusing on the basic principles of dialysis to optimize antibiotic therapy during renal replacement therapy in critically ill patients
10.3390/antibiotics13090864 · 2024 · External reference
Ampicillin pharmacokinetics in azotemic and healthy dogs
10.1111/jvim.16026 · 2021 · External reference
Pharmacokinetic considerations for antimicrobial therapy in patients receiving renal replacement therapy
10.2165/00003088-200746120-00003 · 2007 · External reference
Population pharmacokinetic meta-analysis of five beta-lactams antibiotics to support dosing regimens in dogs for surgical antimicrobial prophylaxis
10.1016/j.tvjl.2024.106136 · 2024 · External reference
Population pharmacokinetics of intravenous ampicillin in awake and anesthetised dogs
10.1016/j.tvjl.2025.106435 · 2025 · External reference
Antimicrobial susceptibilities of geographically diverse clinical human isolates of Leptospira
10.1128/aac.00044-08 · 2008 · External reference
DALI: defining antibiotic levels in intensive care unit patients: are current -lactam antibiotic doses sufficient for critically ill patients?
10.1093/cid/ciu027 · 2014 · External reference
International renal interest society best practice consensus guidelines for the diagnosis and management of acute kidney injury in cats and dogs
2024 · External reference
Pharmacokinetic considerations and dosing strategies of antibiotics in the critically ill patient
10.1177/1751143714564816 · 2015 · External reference
2023 updated consensus statement on leptospirosis in dogs
10.1111/jvim.16903 · 2023 · External reference
Characterization of acute kidney injury in hospitalized dogs and evaluation of a veterinary acute kidney injury staging system: acute kidney injury in dogs
10.1111/j.1476-4431.2011.00689.x · 2011 · External reference
Adsorption of amikacin, a significant mechanism of elimination by hemofiltration
10.1128/aac.00858-07 · 2008 · External reference
Antibiotic dosing in critically ill adult patients receiving continuous renal replacement therapy
10.1086/444500 · 2005 · External reference
The effects of hypoalbuminaemia on optimizing antibacterial dosing in critically ill patients
10.2165/11539220-000000000-00000 · 2011 · External reference
Population pharmacokinetics of intravenous amoxicillin combined with clavulanic acid in healthy and critically ill dogs
10.3389/fvets.2021.770202 · 2021 · External reference
Pharmacokinetics–pharmacodynamics issues relevant for the clinical use of beta-lactam antibiotics in critically ill patients
10.1186/s13054-018-2155-1 · 2018 · External reference
Pharmacokinetics of ampicillin-sulbactam in azotemic and non-azotemic dogs
10.1111/jvp.13506 · 2025 · External reference