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References from Diagnosing sepsis-induced acute lung hypoxia with a mitochondria- targeted far-red nitroreductase-responsive fluorescent probe. Local targets link to admitted publications; unresolved targets remain external evidence.
The epidemiology of acute respiratory distress syndrome in patients presenting to the emergency department with severe sepsis
10.1097/shk.0b013e3182a64682 · 2013 · External reference
Infection site is predictive of outcome in acute lung injury associated with severe sepsis and septic shock
10.1111/resp.12769 · 2016 · External reference
Serial measurements of protein biomarkers in sepsis-induced acute respiratory distress syndrome
2022 · External reference
Acute respiratory distress syndrome
10.1016/s0140-6736(21)00439-6 · 2021 · External reference
Hydrogen-rich medium ameliorates lipopolysaccharides-induced mitochondrial fission and dysfunction in human umbilical vein endothelial cells (HUVECs) via up-regulating HO-1 expression
10.1016/j.intimp.2022.108936 · 2022 · External reference
Dexmedetomidine ameliorates endotoxin-induced acute lung injury in vivo and in vitro by preserving mitochondrial dynamic equilibrium through the HIF-1a/HO-1 signaling pathway
10.1016/j.redox.2021.101954 · 2021 · External reference
Tea polyphenols prevent sepsis-induced lung injury via promoting translocation of DJ-1 to mitochondria
10.3389/fcell.2021.622507 · 2021 · External reference
A-kinase anchor protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury
2022 · External reference
Mitochondria in sickness and in health
10.1016/j.cell.2012.02.035 · 2020 · External reference
SARS-CoV-2 targets host mitochondria and induces cell death
2020 · External reference
Mitochondrial quality control as a therapeutic target
10.1124/pr.115.011502 · 2016 · External reference
Mitochondrial dysfunction and the inflammatory response
10.1016/j.mito.2013.01.003 · 2013 · External reference
Mitochondrial metabolism in alveolar epithelial cells: implications for lung injury and repair
2017 · External reference
Hypoxia induces mitochondrial fission in alveolar epithelial cells via Drp1 activation
2020 · External reference
Mitochondrial DNA damage-associated molecular patterns in acute lung injury
2020 · External reference
Metabolic reprogramming in alveolar epithelial cells under hypoxia: implications for lung repair
2021 · External reference
Effects of hypoxia and reoxygenation on mitochondrial functions and transcriptional profiles of isolated brain and muscle porcine cells
10.1038/s41598-022-24386-0 · 2022 · External reference
Hypoxia, mitochondrial dysfunction, and progression of chronic lung diseases
2021 · External reference
Mitochondria in lung disease
10.1172/jci81113 · 2016 · External reference
Mitochondrial dysfunction in high-altitude pulmonary edema
2019 · External reference
Oxygen-sensitive nitroreductase: a novel prodrug activation pathway for hypoxic tumor cells
2002 · External reference
A new fluorescent probe with a large turn-on signal for imaging nitroreductase in tumor cells and tissues by two-photon microscopy
10.1016/j.bios.2016.09.107 · 2017 · External reference
Hypoxia-driven nitroreductase overexpression promotes chemoresistance in hepatocellular carcinoma
2021 · External reference
Fluorescent probes for hypoxia: design strategies and biological applications
2022 · External reference
A turn-on fluorescent probe for nitroreductase activity and its application in real-time imaging of tumor hypoxia
10.1016/j.talanta.2025.127804 · 2025 · External reference
Ultra-sensitive and fast nitroreductase-responsive fluorescence probe for real-time bioimaging of hypoxia in tumor cells and zebrafish wound inflammation
10.1016/j.snb.2024.136458 · 2024 · External reference
Covalent assembly-based two-photon fluorescent probes for in situ visualizing nitroreductase activities: from cancer cells to human cancer tissues
2024 · External reference
A near-infrared fluorescence probe with large stokes shift for selectively monitoring nitroreductase in living cells and mouse tumor models
10.1016/j.talanta.2024.125976 · 2024 · External reference
Mitochondria-targeted BODIPY dyes for small molecule recognition, bio-imaging and photodynamic therapy
10.1039/d3cs00456b · 2024 · External reference
A novel low-background nitroreductase fuorescent probe for real-time fuorescence imaging and surgical guidance of thyroid cancer resection
10.1016/j.bios.2024.116514 · 2024 · External reference
Sensitive cancer hypoxia detection via a dual-locking fluorescence response system using two hypoxia indicators
2024 · External reference
Harnessing the potential of a nitroreductase-responsive fluorescent probe for the diagnosis of bacterial keratitis
10.1021/acs.bioconjchem.4c00234 · 2024 · External reference
Nitroreductase-based “turn-on” fluorescent probe for bacterial identification with visible features
10.1021/acssensors.3c02785 · 2024 · External reference
A triphenylamine-based near-infrared fluorescence turn off probe for nitroreductase imaging
10.1016/j.dyepig.2023.111807 · 2024 · External reference
A novel nitroreductase-responsive turn-off fluorescent probe based on AIEgen and its bioimaging application
10.1016/j.molstruc.2023.136483 · 2023 · External reference
Rational design of a ratiometric fluorescent probe for imaging lysosomal nitroreductase activity
10.1016/j.saa.2023.123032 · 2023 · External reference
Recent advances in the mitochondria-targeting small molecule fluorescent probes: from the principal design to biological applications
10.1016/j.ccr.2025.217229 · 2026 · External reference
Mitochondrial- targeting fluorescent probe awakened by nitroreductase for hypoxic imaging and surgical navigation of solid tumors
2023 · External reference
A mitochondrial targeted fluorescent probe for imaging nitroreductase activity and photodynamic therapy in tumor cells
2024 · External reference
Fluorogenic and mitochondria-localizable probe enables selective labeling and imaging of nitroreductase
10.1021/acs.analchem.2c00512 · 2022 · External reference
A mitochondria/ lysosome-targeting fluorescence probe based on azonia-cyanine dye and its application in nitroreductase detection
10.1016/j.snb.2019.127653 · 2020 · External reference
Rational construction of a reversible arylazo-based NIR probe for cycling hypoxia imaging in vivo
10.1038/s41467-021-22855-0 · 2021 · External reference
A mitochondria-targeting fluorescent probe for imaging nitroreductase activity and photodynamic therapy in tumor cells
10.1039/c7ob00781g · 2017 · External reference
Single-molecule imaging of active mitochondrial nitroreductases using a photo-crosslinking fluorescent sensor
10.1002/anie.201904700 · 2019 · External reference
A mitochondria-targeting fluorescent probe for imaging nitroreductase activity and photodynamic therapy in tumor cells
10.1016/j.aca.2019.12.063 · 2020 · External reference
Precise imaging of mitochondria in cancer cells by real-time monitoring of nitroreductase activity with a targetable and activatable fluorescent probe
10.1039/d0cc00494d · 2020 · External reference
A lysosome-targeting fluorescence off-on probe for imaging of nitroreductase and hypoxia in live cells
10.1002/asia.201600012 · 2016 · External reference
Lysosome-targeting turn-on red/NIR BODIPY probes for imaging hypoxic cells
10.1039/c9cc04416g · 2019 · External reference
A nitroreductase-responsive fluorescence turn-on photosensitizer for lysosome imaging and photodynamic therapy
10.1016/j.talanta.2024.126277 · 2024 · External reference
Precise monitoring and assessing treatment response of sepsis-induced acute lung hypoxia with a nitroreductase-activated Golgi-targetable fluorescent probe
10.1021/acs.analchem.2c03722 · 2022 · External reference
Endoplasmic reticulum-targeted two-photon turn-on fluorescent probe for nitroreductase in tumor cells and tissues
10.1016/j.saa.2018.05.092 · 2018 · External reference
Natural flavylium-inspired far-red to NIR-II dyes and their applications as fluorescent probes for biomedical sensing
10.1039/d2cs00179a · 2022 · External reference
An asymmetrical flavylium based probe with large stokes shift and near infrared emission for highly sensitive detecting and visualizing cellular drug induced H2S fluctuations
10.1016/j.talanta.2024.125734 · 2024 · External reference
Development of a water-soluble fluorescent probe based on natural flavylium for mercury (II) ion detection and clinical antidote evaluation
10.1021/acs.jafc.3c04537 · 2023 · External reference
Comprehensive monitoring of mitochondrial viscosity variation during different cell death processes by a NIR mitochondria-targeting fluorescence probe
10.1016/j.saa.2023.122602 · 2023 · External reference
Recent progress in the design principles, sensing mechanisms, and applications of small-molecule probes for nitroreductases
10.1016/j.ccr.2020.213460 · 2020 · External reference
Structures of nitroreductase in three states: effects of inhibitor binding and reduction
10.1074/jbc.m111334200 · 2002 · External reference
Ultrasensitive near-infrared fluorescence-enhanced probe for in vivo nitroreductase imaging
10.1021/jacs.5b04097 · 2015 · External reference
Amperometric TNT biosensor based on the oriented immobilization of a nitroreductase maltose binding protein fusion
10.1021/ac010596o · 2002 · External reference
Nitroreductase detection and hypoxic tumor cell imaging by a designed sensitive and selective fluorescent probe, 7-[(5-nitrofuran-2-yl) methoxy]-3H-phenoxazin-3-one
10.1021/ac400750r · 2013 · External reference
Designing a brightness-restored rhodamine derivative by the ortho-compensation effect for assessing drug-induced acute kidney injury
10.1021/acs.analchem.2c05699 · 2023 · External reference
A mitochondria-targeted dual-functional aggregation-induced emission luminogen for intracellular mitochondrial imaging and photodynamic therapy
10.1039/d0bm02099k · 2021 · External reference
An AIEgen-based photosensitizer for lysosome imaging and photodynamic therapy in tumor
10.1016/j.snb.2021.129698 · 2021 · External reference
