Research graph
References from Panta rhei: Chromatin remodeling dynamics. Local targets link to admitted publications; unresolved targets remain external evidence.
Crystal structure of the nucleosome core particle at 2.8 A resolution
10.1038/38444 · 1997 · External reference
Nucleosome remodeling and epigenetics
10.1101/cshperspect.a017905 · 2013 · External reference
Mechanisms of action and regulation of ATP-dependent chromatin-remodelling complexes
10.1038/nrm.2017.26 · 2017 · External reference
Regulating the chromatin landscape: structural and mechanistic perspectives
10.1146/annurev-biochem-051810-093157 · 2014 · External reference
Mechanisms and functions of ATP-dependent chromatin-remodeling enzymes
10.1016/j.cell.2013.07.011 · 2013 · External reference
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms
10.1038/cr.2011.32 · 2011 · External reference
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
10.1038/ng.2628 · 2013 · External reference
SWI/SNF nucleosome remodellers and cancer
10.1038/nrc3068 · 2011 · External reference
Chromatin remodellers as therapeutic targets
10.1038/s41573-024-00978-5 · 2024 · External reference
Chromatin remodeling complexes: architects influencing breast cancer progression
10.3389/fcell.2025.1690350 · 2025 · External reference
10.1126/sciadv.1500447
10.1126/sciadv.1500447 · External reference
BAFfling pathologies: alterations of BAF complexes in cancer
10.1016/j.canlet.2018.01.046 · 2018 · External reference
Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities
10.1016/j.gde.2017.02.004 · 2017 · External reference
Chromatin remodeling BAF (SWI/SNF) complexes in neural development and disorders
10.3389/fnmol.2017.00243 · 2017 · External reference
Loss of function of SWI/SNF chromatin remodeling genes leads to genome instability of human lung cancer
10.3892/or.2014.3584 · 2015 · External reference
Functional landscape of non-canonical open reading frames in coordinating cell fate
10.1016/j.molcel.2026.02.010 · 2026 · External reference
3D variability analysis: resolving continuous flexibility and discrete heterogeneity from single particle cryo-EM
10.1016/j.jsb.2021.107702 · 2021 · External reference
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
10.1038/nmeth.4169 · 2017 · External reference
Chromatin remodeling through directional DNA translocation from an internal nucleosomal site
10.1038/nsmb973 · 2005 · External reference
Chromatin remodeling by RSC involves ATP-dependent DNA translocation
10.1101/gad.995002 · 2002 · External reference
Stepwise nucleosome translocation by RSC remodeling complexes
10.7554/elife.10051 · 2016 · External reference
The RSC chromatin remodelling ATPase translocates DNA with high force and small step size
10.1038/emboj.2011.141 · 2011 · External reference
Direct observation of coordinated DNA movements on the nucleosome during chromatin remodelling
10.1038/s41467-019-09657-1 · 2019 · External reference
Mechanism of chromatin remodelling revealed by the Snf2-nucleosome structure
10.1038/nature22036 · 2017 · External reference
Mechanism of DNA translocation underlying chromatin remodelling by Snf2
10.1038/s41586-019-1029-2 · 2019 · External reference
Structural insights into chromatin remodeling by ISWI during active ATP hydrolysis
10.1126/science.adu5654 · 2025 · External reference
Mechanisms of chromatin remodeling by the human Snf2-type ATPase SNF2H
10.1038/s41422-025-01103-w · 2025 · External reference
Structure and regulation of the chromatin remodeller ISWI
10.1038/nature20590 · 2016 · External reference
The ISW1 and CHD1 ATP-dependent chromatin remodelers compete to set nucleosome spacing in vivo
10.1093/nar/gkw068 · 2016 · External reference
Structure of the ISW1a complex bound to the dinucleosome
10.1038/s41594-023-01174-6 · 2024 · External reference
Distortion of histone octamer core promotes nucleosome mobilization by a chromatin remodeler
10.1126/science.aaa3761 · 2017 · External reference
ISWI is an intrinsically dynamic nucleosome remodeler that induces large-scale histone dynamics
10.1016/j.jmb.2025.169480 · 2025 · External reference
The sequence of nucleosomal DNA modulates sliding by the Chd1 chromatin remodeler
10.1016/j.jmb.2017.02.002 · 2017 · External reference
Chromatin remodeling protein Chd1 interacts with transcription elongation factors and localizes to transcribed genes
10.1093/emboj/cdg179 · 2003 · External reference
Structure and function of chromatin remodelers
10.1016/j.jmb.2021.166929 · 2021 · External reference
The chromodomains of the Chd1 chromatin remodeler regulate DNA access to the ATPase motor
10.1016/j.molcel.2010.08.012 · 2010 · External reference
Nucleosome–Chd1 structure and implications for chromatin remodelling
10.1038/nature24046 · 2017 · External reference
A competitive regulatory mechanism of the Chd1 remodeler is integral to distorting nucleosomal DNA
10.1038/s41594-025-01556-y · 2025 · External reference
Structural basis of human CHD1 nucleosome recruitment and pausing
10.1016/j.molcel.2025.04.020 · 2025 · External reference
Nucleosome recognition and DNA distortion by the Chd1 remodeler in a nucleotide-free state
10.1038/s41594-021-00719-x · 2022 · External reference
Chromatin remodeling by ISW2 and SWI/SNF requires DNA translocation inside the nucleosome
10.1038/nsmb1071 · 2006 · External reference
Probing SWI/SNF remodeling of the nucleosome by unzipping single DNA molecules
10.1038/nsmb1102 · 2006 · External reference
SWI/SNF Unwraps, slides, and rewraps the nucleosome
10.1016/s1097-2765(03)00039-x · 2003 · External reference
Structural architecture of the nucleosome remodeler ISWI determined from cross-linking, mass spectrometry, SAXS, and modeling
10.1016/j.str.2017.12.015 · 2018 · External reference
Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes
10.7554/elife.22510 · 2017 · External reference
Cryo-EM structures of remodeler-nucleosome intermediates suggest allosteric control through the nucleosome
10.7554/elife.46057 · 2019 · External reference
Structure and regulation of the chromatin remodeller ISWI
10.1038/nature20590 · 2016 · External reference
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome
10.1038/s41586-020-2088-0 · 2020 · External reference
A structural model of the endogenous human BAF complex informs disease mechanisms
10.1016/j.cell.2020.09.051 · 2020 · External reference
Structure of nucleosome-bound human BAF complex
10.1126/science.aaz9761 · 2020 · External reference
Structure of human chromatin-remodelling PBAF complex bound to a nucleosome
10.1038/s41586-022-04658-5 · 2022 · External reference
Structure of the RSC complex bound to the nucleosome
10.1126/science.aay0033 · 2019 · External reference
Architecture of the chromatin remodeler RSC and insights into its nucleosome engagement
10.7554/elife.54449 · 2019 · External reference
Structure of nucleosome-bound human PBAF complex
10.1038/s41467-022-34859-5 · 2022 · External reference
Modular organization and assembly of SWI/SNF family chromatin remodeling complexes
10.1016/j.cell.2018.09.032 · 2018 · External reference
The human BAF chromatin remodeler processes nucleosomes bound by pioneer transcription factors OCT4–SOX2
10.1016/j.molcel.2026.01.021 · 2026 · External reference
Dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers
10.7554/elife.91433 · 2024 · External reference
Single-molecule imaging of SWI/SNF chromatin remodelers reveals bromodomain-mediated and cancer-mutants-specific landscape of multi-modal DNA-binding dynamics
10.1038/s41467-024-52040-y · 2024 · External reference
ncBAF recognizes the nucleosome through BCL7A in chromatin remodeling
10.1038/s41421-025-00858-1 · 2025 · External reference
Structural basis for BCL7B-mediated ncBAF-nucleosome engagement
10.1093/nar/gkag092 · 2026 · External reference
Structure of the nucleosome-bound human BCL7A
10.1093/nar/gkaf273 · 2025 · External reference
Cryo-EM structures of the human INO80 chromatin-remodeling complex
10.1038/s41594-017-0003-7 · 2018 · External reference
Structural basis for ATP-dependent chromatin remodelling by the INO80 complex
10.1038/s41586-018-0029-y · 2018 · External reference
Structure and regulation of the human INO80–nucleosome complex
10.1038/s41586-018-0021-6 · 2018 · External reference
Recognition and remodelling of nucleosomes and hexasomes by the human INO80 complex
10.1093/nar/gkag138 · 2026 · External reference
A hexasome is the preferred substrate for the INO80 chromatin remodeling complex, allowing versatility of function
10.1016/j.molcel.2022.04.026 · 2022 · External reference
Hexasome-INO80 complex reveals structural basis of noncanonical nucleosome remodeling
10.1126/science.adf6287 · 2023 · External reference
Structural mechanism of extranucleosomal DNA readout by the INO80 complex
10.1126/sciadv.add3189 · 2022 · External reference
Reorientation of INO80 on hexasomes reveals basis for mechanistic versatility
10.1126/science.adf4197 · 2023 · External reference
Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism
10.1016/j.cell.2019.12.036 · 2020 · External reference
Landscape of mSWI/SNF chromatin remodeling complex perturbations in neurodevelopmental disorders
10.1038/s41588-023-01451-6 · 2023 · External reference
Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy
10.1038/ng.2628 · 2013 · External reference
Mechanism of action of the SWI/SNF family complexes
10.1080/19491034.2023.2165604 · 2023 · External reference
The many roles of BAF (mSWI/SNF) and PBAF complexes in cancer
10.1101/cshperspect.a026930 · 2016 · External reference
Context-specific functions of chromatin remodellers in development and disease
10.1038/s41576-023-00666-x · 2024 · External reference
SMARCB1 missense mutants disrupt SWI/SNF complex stability and remodeling activity
10.1038/s41467-026-71531-8 · 2026 · External reference
SWI/SNF subunit BAF155 N-terminus structure informs the impact of cancer-associated mutations and reveals a potential drug binding site
10.1038/s42003-021-02050-z · 2021 · External reference
Pathogenic variants in SMARCA5 , a chromatin remodeler, cause a range of syndromic neurodevelopmental features
2021 · External reference
Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations
10.7554/elife.56178 · 2020 · External reference
Autoinhibition imposed by a large conformational switch of INO80 regulates nucleosome positioning
10.1126/science.adr3831 · 2025 · External reference
