Research graph
References from Modeling cancer cachexia: From preclinical platforms to biosensing innovations. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer cachexia: new insights and future directions
10.3390/cancers15235590 · 2023 · External reference
Hallmarks of cancer: new dimensions
10.1158/2159-8290.cd-21-1059 · 2022 · External reference
Understanding cachexia as a cancer metabolism syndrome
10.1038/oncsis.2016.3 · 2016 · External reference
Cancer cachexia: a tumor-driven disorder of whole-body homeostasis
10.1016/j.ccell.2026.03.012 · 2026 · External reference
Cancer cachexia: molecular basis and therapeutic advances
10.1038/s41392-025-02331-7 · 2026 · External reference
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10.1002/jcsm.13703 · 2025 · External reference
Definition and classification of cancer cachexia: an international consensus
10.1016/s1470-2045(10)70218-7 · 2011 · External reference
Diagnostic criteria for cancer cachexia: reduced food intake and inflammation predict weight loss and survival in an international, multi-cohort analysis
10.1002/jcsm.12756 · 2021 · External reference
Cancer cachexia: definition, staging, and emerging treatments
10.2147/cmar.s261585 · 2020 · External reference
Cancer cachexia in clinical practice: a review of treatment barriers among cancer patients
2025 · External reference
Diversity in chemotherapy-induced cachexia
10.1152/ajpcell.00773.2024 · 2024 · External reference
Cancer cachexia: molecular mechanisms and treatment strategies
10.1186/s13045-023-01454-0 · 2023 · External reference
Metabolic biomarkers for the early detection of cancer cachexia
2021 · External reference
Omega-3 fatty acid supplementation and its impact on systemic inflammation and body weight in patients with cancer cachexia—a systematic review and meta-analysis
10.3389/fnut.2021.797513 · 2022 · External reference
Anamorelin as a therapeutic option for cancer cachexia in advanced pancreatic cancer: a case report demonstrating significant weight gain and quality of life improvement
10.2169/internalmedicine.4708-24 · 2025 · External reference
A systematic review and meta-analysis of the clinical use of megestrol acetate for cancer-related anorexia/cachexia
10.3390/jcm11133756 · 2022 · External reference
Pentoxifylline treatment in patients with cancer cachexia: a double-blind, randomized, placebo-controlled clinical trial
10.4103/2277-9175.179182 · 2016 · External reference
Espindolol for the treatment and prevention of cachexia in patients with stage III/IV non-small cell lung cancer or colorectal cancer: a randomized, double-blind, placebo-controlled, international multicentre phase II study (the ACT-ONE trial)
10.1002/jcsm.12126 · 2016 · External reference
Targeting cancer cachexia: molecular mechanisms and clinical study
10.1002/mco2.164 · 2022 · External reference
Exploring heterogeneity: a dive into preclinical models of cancer cachexia
10.1152/ajpcell.00317.2024 · 2024 · External reference
Metabolic reprogramming and cancer progression
10.1126/science.aaw5473 · 2020 · External reference
Metabolic regulation of cell growth and proliferation
10.1038/s41580-019-0123-5 · 2019 · External reference
Activation of GPR81 by lactate drives tumour-induced cachexia
10.1038/s42255-024-01011-0 · 2024 · External reference
The role of interleukin-6 family cytokines in cancer cachexia
2024 · External reference
Tumor metabolism as a factor affecting diversity in cancer cachexia
10.1152/ajpcell.00677.2024 · 2025 · External reference
Unravelling the role of cancer cell-derived extracellular vesicles in muscle atrophy, lipolysis, and cancer-associated cachexia
10.3390/cells12222598 · 2023 · External reference
Extracellular vesicles in tumor-adipose tissue crosstalk: key drivers and therapeutic targets in cancer cachexia
10.20517/evcna.2024.36 · 2024 · External reference
Molecular mechanisms of cancer cachexia-related loss of skeletal muscle mass: data analysis from preclinical and clinical studies
10.1002/jcsm.13073 · 2023 · External reference
Vascular collapse leads to muscle wasting in cancer cachexia
10.1038/s43018-025-01002-4 · 2025 · External reference
Muscle inflammation is regulated by NF-κB from multiple cells to control distinct states of wasting in cancer cachexia
10.1016/j.celrep.2024.114925 · 2024 · External reference
EDA2R–NIK signalling promotes muscle atrophy linked to cancer cachexia
10.1038/s41586-023-06047-y · 2023 · External reference
The canonical ER stress IRE1α/XBP1 pathway mediates skeletal muscle wasting during pancreatic cancer cachexia
2025 · External reference
Females display relatively preserved muscle quality compared with males during the onset and early stages of C26-induced cancer cachexia
10.1152/japplphysiol.00196.2023 · 2023 · External reference
Sexual dimorphism modulates the impact of cancer cachexia on lower limb muscle mass and function
10.1016/j.clnu.2011.12.008 · 2012 · External reference
Mitochondrial dysfunction: roles in skeletal muscle atrophy
10.1186/s12967-023-04369-z · 2023 · External reference
Impaired cAMP–PKA–CREB1 signalling drives mitochondrial dysfunction in skeletal muscle during cancer cachexia
10.1038/s42255-025-01397-5 · 2025 · External reference
Muscle weakness precedes atrophy during cancer cachexia and is linked to muscle-specific mitochondrial stress
10.1172/jci.insight.155147 · 2022 · External reference
Cancer cachexia: multilevel metabolic dysfunction
10.1038/s42255-024-01167-9 · 2024 · External reference
Derangements of amino acids in cachectic skeletal muscle are caused by mitochondrial dysfunction
10.1002/jcsm.12498 · 2020 · External reference
Autophagy exacerbates muscle wasting in cancer cachexia and impairs mitochondrial function
10.1016/j.jmb.2019.05.032 · 2019 · External reference
Cancer cachexia in a mouse model of oxidative stress
10.1002/jcsm.12615 · 2020 · External reference
NAD+ repletion with niacin counteracts cancer cachexia
10.1038/s41467-023-37595-6 · 2023 · External reference
Impaired muscle regeneration in cancer-associated cachexia
10.1016/j.trecan.2019.07.010 · 2019 · External reference
Impaired regeneration: a role for the muscle microenvironment in cancer cachexia
10.1016/j.semcdb.2015.09.009 · 2016 · External reference
Inflammation and Skeletal Muscle Wasting During Cachexia
10.3389/fphys.2020.597675 · 2020 · External reference
Group I Paks support muscle regeneration and counteract cancer-associated muscle atrophy
10.1002/jcsm.12303 · 2018 · External reference
The adipokines in cancer cachexia
10.3390/ijms21144860 · 2020 · External reference
Adipose atrophy in cancer cachexia: morphologic and molecular analysis of adipose tissue in tumour-bearing mice
10.1038/sj.bjc.6603360 · 2006 · External reference
Adipose-tissue plasticity in health and disease
10.1016/j.cell.2021.12.016 · 2022 · External reference
Adipose triglyceride lipase contributes to cancer-associated cachexia
10.1126/science.1198973 · 2011 · External reference
Mechanism of increased lipolysis in cancer cachexia
10.1158/0008-5472.can-06-4585 · 2007 · External reference
Cytokine-Mediated STAT3 Transcription Supports ATGL/CGI-58-Dependent Adipocyte Lipolysis in Cancer Cachexia
10.3389/fonc.2022.841758 · 2022 · External reference
Assessment of lipolysis biomarkers in adipose tissue of patients with gastrointestinal cancer
10.1186/s40170-023-00329-9 · 2024 · External reference
Lipases and lipid droplet-associated protein expression in subcutaneous white adipose tissue of cachectic patients with cancer
10.1186/s12944-017-0547-x · 2017 · External reference
Inter-tissue communication in cancer cachexia
10.1038/s41574-018-0123-0 · 2018 · External reference
Cachexia-associated adipose loss induced by tumor-secreted leukemia inhibitory factor is counterbalanced by decreased leptin
10.1172/jci.insight.121221 · 2018 · External reference
Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia
10.1002/jcsm.13109 · 2023 · External reference
Antibody-mediated inhibition of GDF15-GFRAL activity reverses cancer cachexia in mice
10.1038/s41591-020-0945-x · 2020 · External reference
An AMP-activated protein kinase–stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice
10.1038/nm.4171 · 2016 · External reference
CircAMOTL1 promotes adipose lipolysis and browning in cancer cachexia through miR-211-5p-mediated TET2 activation
10.1016/j.jbc.2025.111052 · 2026 · External reference
Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia
10.1038/s41467-023-40571-9 · 2023 · External reference
Exosomal miRNA 16-5p/29a-3p from pancreatic cancer induce adipose atrophy by inhibiting adipogenesis and promoting lipolysis
10.1016/j.isci.2024.110346 · 2024 · External reference
JAK Inhibitors Suppress Cancer Cachexia-Associated Anorexia and Adipose Wasting in Mice
10.1002/rco2.24 · 2020 · External reference
Evidence for an important role of CIDEA in human cancer cachexia
10.1158/0008-5472.can-08-1343 · 2008 · External reference
Low levels of lipogenic enzymes in peritumoral adipose tissue of colorectal cancer patients
10.1007/s11745-011-3630-5 · 2012 · External reference
Decrease in malonyl-CoA and its background metabolic alterations in murine model of cancer cachexia
2009 · External reference
Breast cancer cell-derived exosome-delivered microRNA-155 targets UBQLN1 in adipocytes and facilitates cancer cachexia-related fat loss
10.1093/hmg/ddad055 · 2023 · External reference
Leukemia inhibitory factor suppresses hepatic de novo lipogenesis and induces cachexia in mice
10.1038/s41467-024-44924-w · 2024 · External reference
Interleukin 6 as a key regulator of muscle mass during cachexia
10.1097/jes.0b013e3181f44f11 · 2010 · External reference
A switch from white to brown fat increases energy expenditure in cancer-associated cachexia
10.1016/j.cmet.2014.06.011 · 2014 · External reference
An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia
10.1073/pnas.2112840119 · 2022 · External reference
Interleukin-6 induces fat loss in cancer cachexia by promoting white adipose tissue lipolysis and browning
10.1186/s12944-018-0657-0 · 2018 · External reference
Tumour-derived PTH-related protein triggers adipose tissue browning and cancer cachexia
10.1038/nature13528 · 2014 · External reference
The tumor secretory factor ZAG promotes white adipose tissue browning and energy wasting
10.1096/fj.201701465rr · 2018 · External reference
NAG-1/GDF-15 prevents obesity by increasing thermogenesis, lipolysis and oxidative metabolism
10.1038/ijo.2014.27 · 2014 · External reference
Cancer-associated cachexia — understanding the tumour macroenvironment and microenvironment to improve management
10.1038/s41571-023-00734-5 · 2023 · External reference
The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia
10.1016/j.ccell.2024.03.009 · 2024 · External reference
Immunoregulation in cancer-associated cachexia
10.1016/j.jare.2023.04.018 · 2024 · External reference
The Emerging Role of Interleukin 1β (IL-1β) in Cancer Cachexia
10.1007/s10753-021-01429-8 · 2021 · External reference
IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models
10.1038/s41467-020-18244-8 · 2020 · External reference
The central role of hypothalamic inflammation in the acute illness response and cachexia
2016 · External reference
Tumor Tissue Affects the Activity of the Nervous System
2024 · External reference
Atractylodin alleviates cancer anorexia-cachexia syndrome by regulating NPY through hypothalamic Sirt1/AMPK axis-induced autophagy
10.1016/j.bbrc.2022.08.011 · 2022 · External reference
Parathyroid hormone related protein (PTHrP) in patients with pancreatic carcinoma and overt signs of disease progression and host tissue wasting
10.1016/j.tranon.2023.101752 · 2023 · External reference
Development of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model
10.1371/journal.pone.0173113 · 2017 · External reference
Significant weight gain benefits of nanocrystalline megestrol acetate for patients with cancer anorexia-cachexia syndrome
10.21037/tcr-2025-866 · 2025 · External reference
Gut microbiota in cancer cachexia: a new frontier for research and therapy
10.1186/s12263-025-00791-8 · 2025 · External reference
Gut barrier dysfunction and microbial translocation in cancer cachexia: a new therapeutic target
10.1097/spc.0000000000000017 · 2013 · External reference
The gut dysbiosis-cancer axis: illuminating novel insights and implications for clinical practice
10.3389/fphar.2023.1208044 · 2023 · External reference
Gut microbiota and metabolic aspects of cancer cachexia
10.1016/j.beem.2021.101508 · 2021 · External reference
Gut microbiota and short-chain fatty acid alterations in cachectic cancer patients
10.1002/jcsm.12804 · 2021 · External reference
The metabolite butyrate produced by gut microbiota inhibits cachexia-associated skeletal muscle atrophy by regulating intestinal barrier function and macrophage polarization
10.1016/j.intimp.2023.111001 · 2023 · External reference
The pathophysiology of cancer-mediated cardiac cachexia and novel treatment strategies: A narrative review
10.1002/cam4.6388 · 2023 · External reference
Muscle wasting and cachexia in heart failure: mechanisms and therapies
10.1038/nrcardio.2017.51 · 2017 · External reference
Cardiac Complications: The Understudied Aspect of Cancer Cachexia
10.1007/s12012-022-09727-9 · 2022 · External reference
Role of mitochondrial dysfunction in muscle wasting in cancer cachexia: a narrative review
10.1186/s12967-026-07906-8 · 2026 · External reference
Cardiac Remodeling in Cancer-Induced Cachexia: Functional, Structural, and Metabolic Contributors
10.3390/cells11121931 · 2022 · External reference
Understanding the common mechanisms of heart and skeletal muscle wasting in cancer cachexia
10.1038/s41389-020-00288-6 · 2021 · External reference
Malnutrition, cachexia and sarcopenia as susceptibility factors for cardiovascular complications in patients with cancer
10.3389/fphar.2026.1762196 · 2026 · External reference
C-Reactive Protein Level: A Key Predictive Marker of Cachexia in Lymphoma and Myeloma Patients
10.14740/jh536 · 2019 · External reference
Serum amyloid A1 mediates myotube atrophy via Toll-like receptors
10.1002/jcsm.12491 · 2020 · External reference
Distinct glycolytic pathway regulation in liver, tumour and skeletal muscle of mice with cancer cachexia
10.1002/cbf.3652 · 2021 · External reference
Prognostic Relationship Between the Cachexia Index and Osteopenia in Patients With Pancreatic Cancer
10.21873/anticanres.17509 · 2025 · External reference
Differential Bone Loss in Mouse Models of Colon Cancer Cachexia
2016 · External reference
Growth of ovarian cancer xenografts causes loss of muscle and bone mass: a new model for the study of cancer cachexia
10.1002/jcsm.12311 · 2018 · External reference
Concurrent muscle and bone deterioration in a murine model of cancer cachexia
10.1002/phy2.144 · 2013 · External reference
Bone Marrow Homeostasis Is Impaired via JAK/STAT and Glucocorticoid Signaling in Cancer Cachexia Model
10.3390/cancers13051059 · 2021 · External reference
NF-κB signaling and bone resorption
10.1007/s00198-013-2313-x · 2013 · External reference
RANKL Blockade Reduces Cachexia and Bone Loss Induced by Non-Metastatic Ovarian Cancer in Mice
10.1002/jbmr.4480 · 2022 · External reference
Role of myokines and osteokines in cancer cachexia
10.1177/15353702211009213 · 2021 · External reference
A catecholamine-independent pathway controlling adaptive adipocyte lipolysis
10.1038/s42255-025-01424-5 · 2026 · External reference
Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia
10.1186/s13287-020-02120-9 · 2021 · External reference
Novel role for tumor-induced expansion of myeloid-derived cells in cancer cachexia
10.4049/jimmunol.1302895 · 2014 · External reference
Myeloid-derived suppressor cells in cancer cachexia syndrome: a new explanation for an old problem
10.1177/0148607108325075 · 2008 · External reference
Depleting Ly6G Positive Myeloid Cells Reduces Pancreatic Cancer-Induced Skeletal Muscle Atrophy
10.3390/cells11121893 · 2022 · External reference
Modeling Human Cancer-induced Cachexia
10.1016/j.celrep.2019.07.016 · 2019 · External reference
Promising models for cancer-induced cachexia drug discovery
10.1080/17460441.2020.1724954 · 2020 · External reference
A comprehensive review of animal models for cancer cachexia: Implications for translational research
2024 · External reference
Development of an efficient mice model of cancer-associated cardiac cachexia
10.1002/ame2.70060 · 2025 · External reference
LP07 and LLC preclinical models of lung cancer induce divergent anabolic deficits and expression of pro-inflammatory effectors of muscle wasting
10.1152/japplphysiol.00246.2022 · 2022 · External reference
Modeling human cancer cachexia in colon 26 tumor-bearing adult mice
10.1007/s13539-014-0141-2 · 2014 · External reference
Cachexia induced by Walker 256 tumor growth causes rat lymphocyte death
10.1007/s00262-004-0570-4 · 2005 · External reference
The Colon-26 Carcinoma Tumor-bearing Mouse as a Model for the Study of Cancer Cachexia
10.3791/54893 · 2016 · External reference
The Pivotal Role of Preclinical Animal Models in Anti-Cancer Drug Discovery and Personalized Cancer Therapy Strategies
2024 · External reference
Early adipose tissue wasting in a preclinical model of human lung cancer cachexia
10.1016/j.celrep.2025.116278 · 2025 · External reference
Protocol for establishing and evaluating a cancer cachexia mouse model
10.1016/j.xpro.2024.103281 · 2024 · External reference
Distinct cachexia profiles in response to human pancreatic tumours in mouse limb and respiratory muscle
10.1002/jcsm.12550 · 2020 · External reference
Patient-derived organoid xenografts model esophageal cancer cachexia and enable assessment of anti-inflammatory drug repositioning
10.1016/j.isci.2026.114638 · 2026 · External reference
Patient-derived xenograft models in cancer therapy: technologies and applications
10.1038/s41392-023-01419-2 · 2023 · External reference
Metabolic difference between patient-derived xenograft model of pancreatic ductal adenocarcinoma and corresponding primary tumor
10.1186/s12885-024-12193-x · 2024 · External reference
Chapter 3 - Challenges and Limitations of Mouse Xenograft Models of Cancer
2017 · External reference
Activity level, apoptosis, and development of cachexia in Apc(Min/+) mice
10.1152/japplphysiol.00442.2010 · 2010 · External reference
Genetically Engineered Mouse Models of Pancreatic Cancer: The KPC Model (LSL-Kras(G12D/+);LSL-Trp53(R172H/+);Pdx-1-Cre), Its Variants, and Their Application in Immuno-oncology Drug Discovery
10.1002/cpph.2 · 2016 · External reference
An implantable device for wireless monitoring of diverse physio-behavioral characteristics in freely behaving small animals and interacting groups
10.1016/j.neuron.2024.02.020 · 2024 · External reference
Implantable Electrochemical Microsensors for In Vivo Monitoring of Animal Physiological Information
2023 · External reference
Human disease models in drug development
10.1038/s44222-023-00063-3 · 2023 · External reference
Cell culture: in vitro model system and a promising path to in vivo applications
10.1080/01478885.2023.2170772 · 2023 · External reference
Vitro models for cancer-associated cachexia: the complex modelling of a multiorgan syndrome
10.3390/app14135419 · 2024 · External reference
Fucoxanthin rescues dexamethasone induced C2C12 myotubes atrophy
10.1016/j.biopha.2021.111590 · 2021 · External reference
Cancer-Cachexia-Induced Human Skeletal Muscle Myotube Degeneration Is Prevented via Cannabinoid Receptor 2 Agonism In Vitro
2023 · External reference
Alantolactone ameliorates cancer cachexia-associated muscle atrophy mainly by inhibiting the STAT3 signaling pathway
10.1016/j.phymed.2021.153858 · 2022 · External reference
M2 macrophage-derived TGF-β induces age-associated loss of adipogenesis through progenitor cell senescence
10.1016/j.molmet.2024.101943 · 2024 · External reference
Serum-free cultures of C2C12 cells show different muscle phenotypes which can be estimated by metabolic profiling
10.1038/s41598-022-04804-z · 2022 · External reference
Toward efficient beige adipogenesis: protocol optimization using adipose-derived stem cells
10.3390/cells15010054 · 2025 · External reference
Novel oral compound Z526 mitigates cancer-associated cachexia via intervening NF-κB signaling and oxidative stress
2025 · External reference
Chemotherapy-induced myopathy: the dark side of the cachexia sphere
10.3390/cancers13143615 · 2021 · External reference
Linalool Prevents Cisplatin Induced Muscle Atrophy by Regulating IGF-1/Akt/FoxO Pathway
10.3389/fphar.2020.598166 · 2020 · External reference
Physiological culture conditions alter myotube morphology and responses to atrophy treatments: implications for in vitro research on muscle wasting
10.14814/phy2.13726 · 2018 · External reference
Effects of conditioned media from murine lung cancer cells and human tumor cells on cultured myotubes
10.1152/ajpendo.00310.2019 · 2020 · External reference
A Novel Role of Bergamottin in Attenuating Cancer Associated Cachexia by Diverse Molecular Mechanisms
10.3390/cancers13061347 · 2021 · External reference
A TGF-β/KLF10 signaling axis regulates atrophy-associated genes to induce muscle wasting in pancreatic cancer
10.1073/pnas.2215095120 · 2023 · External reference
Continuous release of tumor-derived factors improves the modeling of cachexia in muscle cell culture
10.3389/fphys.2017.00738 · 2017 · External reference
Cancer‑associated adipocytes exhibit distinct phenotypes and facilitate tumor progression in pancreatic cancer
2019 · External reference
Surface-directed engineering of tissue anisotropy in microphysiological models of musculoskeletal tissue
10.1126/sciadv.abe9446 · 2021 · External reference
Spheroids in cancer research: Recent advances and opportunities
2024 · External reference
ZIP4 Promotes Muscle Wasting and Cachexia in Mice With Orthotopic Pancreatic Tumors by Stimulating RAB27B-Regulated Release of Extracellular Vesicles From Cancer Cells
10.1053/j.gastro.2018.10.026 · 2019 · External reference
Modeling Tumor Microenvironment Complexity In Vitro: Spheroids as Physiologically Relevant Tumor Models and Strategies for Their Analysis
10.3390/cells14100732 · 2025 · External reference
From 2D cultures to 3D systems: evolving cancer models at the interface of functional precision medicine and theranostics
10.7150/thno.127053 · 2026 · External reference
A comprehensive review on 3D tissue models: Biofabrication technologies and preclinical applications
10.1016/j.biomaterials.2023.122408 · 2024 · External reference
Exosomes in the pathogenesis and treatment of cancer-related cachexia
10.1186/s12967-024-05201-y · 2024 · External reference
Exosomal IL-8 derived from Lung Cancer and Colon Cancer cells induced adipocyte atrophy via NF-κB signaling pathway
10.1186/s12944-022-01755-2 · 2022 · External reference
A comprehensive review on recent advances in exosome isolation and characterization: Toward clinical applications
10.1016/j.tranon.2024.102121 · 2024 · External reference
Pharmacological Inhibition of HMGB1 Prevents Muscle Wasting
2021 · External reference
Jr., LLC tumor cells-derivated factors reduces adipogenesis in co-culture system.
10.1016/j.heliyon.2018.e00708 · 2018 · External reference
Calpain inhibitors inhibit mitochondrial calpain activity to ameliorate apoptosis of cocultured myoblast
10.4103/0304-4920.359797 · 2022 · External reference
Brown adipocytes promote epithelial mesenchymal transition of neuroblastoma cells by inducing PPAR-γ/UCP2 expression
10.1080/21623945.2022.2073804 · 2022 · External reference
Beyond 2D cell cultures: how 3D models are changing the in vitro study of ovarian cancer and how to make the most of them
10.7717/peerj.17603 · 2024 · External reference
Role of three-dimensional cell culture in therapeutics and diagnostics: an updated review
10.1007/s13346-023-01327-6 · 2023 · External reference
3D tumor spheroids: an overview on the tools and techniques used for their analysis
10.1016/j.biotechadv.2016.11.002 · 2016 · External reference
Scaffold-based 3D cell culture models in cancer research
10.1186/s12929-024-00994-y · 2024 · External reference
3D Hydrogel Cell Cultures and Their Biomedical Applications
10.1002/anbr.202500133 · 2026 · External reference
Three-Dimensional Culture of Epithelial Cells on Electrospun Nanofibrous Scaffolds
10.3390/ijms262110500 · 2025 · External reference
Decellularized scaffolds in regenerative medicine
10.18632/oncotarget.10945 · 2016 · External reference
3D bioprinted functional skeletal muscle models have potential applications for studies of muscle wasting in cancer cachexia
10.1016/j.bioadv.2023.213426 · 2023 · External reference
Microfluidics for 3D Cell and Tissue Cultures: Microfabricative and Ethical Aspects Updates
10.3390/cells11101699 · 2022 · External reference
Microfluidic platforms for extracellular vesicle isolation, analysis and therapy in cancer
10.1039/d2lc00006g · 2022 · External reference
Microfluidic-Based Multi-Organ Platforms for Drug Discovery
10.3390/mi7090162 · 2016 · External reference
Studying metabolism with multi-organ chips: new tools for disease modelling, pharmacokinetics and pharmacodynamics
10.1098/rsob.210333 · 2022 · External reference
Immunity-on-a-Chip: Integration of Immune Components into the Scheme of Organ-on-a-Chip Systems
10.1002/adbi.202200312 · 2023 · External reference
Adipose tissue and skeletal muscle wasting precede clinical diagnosis of pancreatic cancer
10.1038/s41467-023-40024-3 · 2023 · External reference
Hand grip strength-based cachexia index as a predictor of cancer cachexia and prognosis in patients with cancer
10.1002/jcsm.13139 · 2023 · External reference
Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines(☆)
10.1016/j.esmoop.2021.100092 · 2021 · External reference
Circadian sleep-wake rhythm reversal in mice implanted with stomach cancer cell lines
10.1016/j.jphyss.2025.100007 · 2025 · External reference
Characterization of cachexia in the human fibrosarcoma HT-1080 mouse tumour model
10.1002/jcsm.12618 · 2020 · External reference
The current use of ultrasound to measure skeletal muscle and its ability to predict clinical outcomes: a systematic review
10.1002/jcsm.13041 · 2022 · External reference
MicroCT enables simultaneous longitudinal tracking of murine pancreatic cancer progression and cachexia
2025 · External reference
Relationships of emerging biomarkers of cancer cachexia with quality of life, appetite, and cachexia
2024 · External reference
Elevated expression of activins promotes muscle wasting and cachexia
10.1096/fj.13-245894 · 2014 · External reference
The impact of inflammation and acute phase activation in cancer cachexia
10.3389/fimmu.2023.1207746 · 2023 · External reference
Circulating interleukin-6 is associated with disease progression, but not cachexia in pancreatic cancer
10.1016/j.pan.2018.11.002 · 2019 · External reference
Kinetic profiling in one-step digital immunoassays enables multiplex quantification across an ultrabroad dynamic range
10.1021/jacs.5c17838 · 2026 · External reference
Pancreatic cancer-derived extracellular vesicles enriched with miR-223-5p promote skeletal muscle wasting associated with cachexia
10.1002/advs.202504064 · 2025 · External reference
Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer
10.1038/s41467-022-32135-0 · 2022 · External reference
Mass spectrometric detection of candidate protein biomarkers of cancer cachexia in human urine
2010 · External reference
An elevated neutrophil-to-lymphocyte ratio associates with weight loss and cachexia in cancer
10.1038/s41598-020-64282-z · 2020 · External reference
Circulating inflammatory and mitochondrial biomarkers associated with cachexia in advanced non-small cell lung cancer
10.3390/cancers18040655 · 2026 · External reference
Association of systemic inflammation with survival in patients with cancer cachexia: results from a multicentre cohort study
10.1002/jcsm.12761 · 2021 · External reference
A flexible wireless sEMG system for wearable muscle strength and fatigue monitoring in real time
10.1002/aelm.202200916 · 2023 · External reference
A stretchable, conductive thread-based sensor towards wearable monitoring of muscle atrophy
10.1109/tbme.2023.3248959 · 2023 · External reference
Wireless, multisensor integrated bioelectronics for real-time monitoring and assessment of muscle atrophy
10.1021/acs.nanolett.4c05245 · 2025 · External reference
Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia
10.1038/nm.4093 · 2016 · External reference
Separating food intake-dependent and -independent effects in cancer cachexia
10.1016/j.isci.2026.115525 · 2026 · External reference
Muscle-on-a-chip with an on-site multiplexed biosensing system for in situ monitoring of secreted IL-6 and TNF-α
10.1039/c9lc00285e · 2019 · External reference
Fabrication of a disposable non-enzymatic electrochemical creatinine sensor
10.1016/j.snb.2016.11.158 · 2017 · External reference
Plasmonic nanocrystals on polycarbonate substrates for direct and label-free biodetection of Interleukin-6 in bioengineered 3D skeletal muscles
10.1515/nanoph-2021-0426 · 2021 · External reference
Training-on-a-chip: a multi-organ device to study the effect of muscle exercise on insulin secretion in vitro
10.1002/admt.202200873 · 2023 · External reference
Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures
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Rapid lipolytic oscillations in ex vivo adipose tissue explants revealed through microfluidic droplet sampling at high temporal resolution
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