Research graph
References from CDKAL1 rs7756992 polymorphism and the risk of type 2 diabetes among Moroccans: A systematic review and meta-analysis. Local targets link to admitted publications; unresolved targets remain external evidence.
Prevalence and risk factors of chronic complications among patients with type 2 diabetes mellitus in Morocco: a cross-sectional study
2022 · External reference
Epidemiology of type 2 diabetes in the Middle East and North Africa: challenges and call for action
10.4239/wjd.v12.i9.1401 · 2021 · External reference
Unresolved reference
2025 · External reference
Genetics of type 2 diabetes: implications from large-scale studies
10.1007/s11892-022-01462-3 · 2022 · External reference
An expanded genome-wide association study of type 2 diabetes in Europeans
10.2337/db16-1253 · 2017 · External reference
Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
10.1126/science.1142358 · 2007 · External reference
Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes
10.1126/science.1142364 · 2007 · External reference
CDKAL1 and type 2 diabetes: a global meta-analysis
10.4238/vol9-2gmr802 · 2010 · External reference
Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic β-cell function
10.2337/db07-0634 · 2007 · External reference
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews
2021 · External reference
Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
10.1002/sim.3034 · 2008 · External reference
Recent developments in meta-analysis
10.1002/sim.2934 · 2008 · External reference
European genetic variants associated with type 2 diabetes in North African Arabs
10.1016/j.diabet.2012.02.003 · 2012 · External reference
How should we use information about HWE in the meta-analyses of genetic association studies?
10.1093/ije/dym234 · 2008 · External reference
Systematic review and meta-analysis of the association between β2-adrenoceptor polymorphisms and asthma: a HuGE review
10.1093/aje/kwi184 · 2005 · External reference
TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global meta-analysis
10.1007/s00109-007-0203-4 · 2007 · External reference
Post genome-wide association studies of novel genes associated with type 2 diabetes show gene–gene interaction and high predictive value
10.1371/journal.pone.0002031 · 2008 · External reference
Newcastle-Ottawa Scale: comparing reviewers’ to authors’ assessments
10.1186/1471-2288-14-45 · 2014 · External reference
Hardy–Weinberg equilibrium in genetic association studies: an empirical evaluation of reporting, deviations, and power
10.1038/sj.ejhg.5201410 · 2005 · External reference
The Hartung–Knapp–Sidik–Jonkman method for random effects meta-analysis is straightforward and considerably outperforms the standard DerSimonian–Laird method
10.1186/1471-2288-14-25 · 2014 · External reference
Methods to estimate the between-study variance and its uncertainty in meta-analysis
10.1002/jrsm.1164 · 2016 · External reference
Prediction intervals for random-effects meta-analysis: a confidence distribution approach
10.1177/0962280218773520 · 2019 · External reference
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
10.1136/bmj.d4002 · 2011 · External reference
The heterogeneity statistic I2 can be biased in small meta-analyses
10.1186/s12874-015-0024-z · 2015 · External reference
Significant association of polymorphisms in the tcf7l2 gene with a higher risk of type 2 diabetes in a Moroccan population
10.3390/jpm11060461 · 2021 · External reference
Association analysis of IGF2BP2, KCNJ11, and CDKAL1 polymorphisms with type 2 diabetes mellitus in a Moroccan population: a case–control study and meta-analysis
10.1007/s10528-014-9658-5 · 2014 · External reference
CDKAL1 gene rs7756992 A/G polymorphism and type 2 diabetes mellitus: a meta-analysis of 62,567 subjects
10.1038/srep03131 · 2013 · External reference
T2DM GWAS in the Lebanese population confirms the role of TCF7L2 and CDKAL1 in disease susceptibility
10.1038/srep07351 · 2014 · External reference
Association of CDKAL1, CDKN2A/B & HHEX gene polymorphisms with type 2 diabetes mellitus in the population of Hyderabad, India
10.4103/0971-5916.184303 · 2016 · External reference
Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population
10.2337/db07-0979 · 2008 · External reference
Association of CDKAL1 gene polymorphisms with type 2 diabetes mellitus in a sample of Iraqi population
2021 · External reference
Single-nucleotide polymorphism rs7754840 of CDKAL1 is associated with impaired insulin secretion in nondiabetic offspring of type 2 diabetic subjects and in a large sample of men with normal glucose tolerance
10.1210/jc.2007-2218 · 2008 · External reference
Inhibition of Cdk5 promotes b-cell differentiation from ductal progenitors
10.2337/db16-1587 · 2018 · External reference
Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity
10.1074/jbc.m604690200 · 2006 · External reference
Quantitative trait analysis of type 2 diabetes susceptibility loci identified from whole genome association studies in the insulin resistance atherosclerosis family study
10.2337/db07-1169 · 2008 · External reference
Variants of CDKAL1 and IGF2BP2 affect first-phase insulin secretion during hyperglycaemic clamps
10.1007/s00125-008-1083-z · 2008 · External reference
Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population
10.2337/db08-0047 · 2008 · External reference
