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References from Right size, right time: The Hippo-IGF2 axis calibrates liver growth and regeneration. Local targets link to admitted publications; unresolved targets remain external evidence.
IGF2 acts downstream of Hippo signaling to regulate organ growth and restore liver regeneration in aging
10.1016/j.stem.2026.08.006 · 2026 · External reference
YAP1 increases organ size and expands undifferentiated progenitor cells
10.1016/j.cub.2007.10.039 · 2007 · External reference
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control
10.1101/gad.1602907 · 2007 · External reference
Disruption of insulin-like growth factor 2 imprinting in Beckwith-Wiedemann syndrome
10.1038/ng1093-143 · 1993 · External reference
YAP Regulates Hematopoietic Stem Cell Formation in Response to the Biomechanical Forces of Blood Flow
10.1016/j.devcel.2020.01.006 · 2020 · External reference
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth
10.1038/ncb3389 · 2016 · External reference
Disruption of the Igf2 gene alters hepatic lipid homeostasis and gene expression in the newborn mouse
10.1152/ajpendo.00048.2018 · 2018 · External reference
Steatotic liver disease induces YAP/TAZ-driven cell competition that can suppress tumor initiation
10.1016/j.jhep.2025.06.002 · 2025 · External reference
The effects of donor age on organ transplants: A review and implications for aging research
10.1016/j.exger.2018.06.019 · 2018 · External reference
Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling
10.7554/elife.53071 · 2020 · External reference
