Research graph
References from The m6A epitranscriptome and the emerging role of m6Am: Molecular hubs for regulating abiotic stress tolerance in cotton. Local targets link to admitted publications; unresolved targets remain external evidence.
Overexpression of the apple m6A demethylase gene MdALKBH1A regulates resistance to heat stress and fixed-carbon starvation
10.1016/j.jia.2025.01.001 · 2025 · External reference
The role of m6A and m6Am RNA modifications in the pathogenesis of diabetes mellitus
10.3389/fendo.2023.1223583 · 2023 · External reference
The m6A reader SlYTH2 negatively regulates tomato fruit aroma by impeding the translation process
10.1073/pnas.2405100121 · 2024 · External reference
The m6A-YTH regulatory system in plants: a status
10.1016/j.pbi.2024.102650 · 2024 · External reference
RNA modifications in plant adaptation to abiotic stresses
10.1016/j.xplc.2024.101229 · 2025 · External reference
The m6A reader ECT8 is an abiotic stress sensor that accelerates mRNA decay in arabidopsis
10.1093/plcell/koae149 · 2024 · External reference
Regulation of gene expression by m6Am RNA modification
10.3390/ijms24032277 · 2023 · External reference
Dynamic profiles of DNA methylation and the interaction with histone acetylation during fiber cell initiation of Gossypium hirsutum
10.1186/s42397-022-00115-w · 2022 · External reference
The comprehensive interactomes of human adenosine RNA methyltransferases and demethylases reveal distinct functional and regulatory features
10.1093/nar/gkab900 · 2021 · External reference
GhALKBH10 negatively regulates salt tolerance in cotton
10.1016/j.plaphy.2022.09.029 · 2022 · External reference
mRNA methylation at the crossroads of translation, transport, and decay in plant development and stress responses
10.1016/j.pbi.2025.102851 · 2026 · External reference
The role of m6A/m-RNA methylation in stress response regulation
10.1016/j.neuron.2018.07.009 · 2018 · External reference
Unraveling the RNA tapestry: a symphony of innovations in m6A research technology
10.1002/ijch.202400014 · 2024 · External reference
Integrating genetic assortment and molecular insights for climate-resilient breeding to unravel drought tolerance in cotton
10.1016/j.jbiotec.2024.08.013 · 2024 · External reference
Genome editing in cotton with the CRISPR/Cas9 system
10.3389/fpls.2017.01364 · 2017 · External reference
Insights into the m6A demethylases FTO and ALKBH5: structural, biological function, and inhibitor development
10.1186/s13578-024-01286-6 · 2024 · External reference
The m6A reader MhYTP2 regulates the stability of its target mRNAs contributing to low nitrogen tolerance in apple (Malus domestica)
10.1093/hr/uhad094 · 2023 · External reference
Heat stress responses mediated by N6-methyladenine DNA methylation in maize
10.1016/j.celrep.2025.116058 · 2025 · External reference
ALKBH10B-mediated m6A demethylation is crucial for drought tolerance by affecting mRNA stability in arabidopsis
10.1016/j.envexpbot.2023.105306 · 2023 · External reference
m6A RNA methylation: from mechanisms to therapeutic potential
10.15252/embj.2020105977 · 2021 · External reference
N6-methyladenosine RNA modification regulates photoperiod sensitivity in cotton
10.1093/plphys/kiae371 · 2024 · External reference
Detection of m6A from direct RNA sequencing using a multiple instance learning framework
10.1038/s41592-022-01666-1 · 2022 · External reference
Epitranscriptomics: RNA modifications in bacteria and archaea
10.1128/microbiolspec.rwr-0015-2017 · 2018 · External reference
Biological roles of the RNA m6A modification and its implications in cancer
10.1038/s12276-022-00897-8 · 2022 · External reference
MdMTA-mediated m6A modification enhances drought tolerance by promoting mRNA stability and translation efficiency of genes involved in lignin deposition and oxidative stress
10.1111/nph.18069 · 2022 · External reference
Epitranscriptomic mRNA modifications governing plant stress responses: underlying mechanism and potential application
10.1111/pbi.13913 · 2022 · External reference
The biogenesis and precise control of RNA m6A methylation
10.1016/j.tig.2019.10.011 · 2020 · External reference
The role of m6A modification in the biological functions and diseases
2021 · External reference
Regulation of m6Am RNA modification and its implications in human diseases
10.1093/jmcb/mjae012 · 2024 · External reference
Nanopore direct RNA sequencing of human transcriptomes reveals the complexity of mRNA modifications and crosstalk between regulatory features
2025 · External reference
N6-methyladenosine RNA methylation: from regulatory mechanisms to potential clinical applications
10.3389/fcell.2022.1055808 · 2022 · External reference
N6-methyladenosine RNA modification regulates cotton drought response in a Ca2+ and ABA-dependent manner
10.1111/pbi.14036 · 2023 · External reference
TMK4-mediated FIP37 phosphorylation regulates auxin-triggered N6-methyladenosine modification of auxin biosynthetic genes in arabidopsis
10.1016/j.celrep.2024.114597 · 2024 · External reference
A high-efficiency CRISPR/Cas9 system for targeted mutagenesis in Cotton (Gossypium hirsutum L.)
2017 · External reference
Cotton2035: From genomics research to optimized breeding
10.1016/j.molp.2025.01.010 · 2025 · External reference
Unique features of the m6A methylome and its response to salt stress in the roots of sugar beet (Beta vulgaris)
2023 · External reference
Nanopore-based comparative transcriptome analysis reveals the potential mechanism of high-temperature tolerance in cotton (Gossypium hirsutum L.)
10.3390/plants10112517 · 2021 · External reference
Single-nucleotide resolution mapping of m6A and m6Am throughout the transcriptome
10.1038/nmeth.3453 · 2015 · External reference
Landscape and regulation of m6A and m6Am methylome across Human and mouse tissues
10.1016/j.molcel.2019.09.032 · 2020 · External reference
Genome-wide identification and functional analysis of mRNA m6A writers in soybean under abiotic stress
2024 · External reference
Programmable RNA N6-methyladenosine editing by CRISPR-Cas9 conjugates
10.1038/s41589-019-0327-1 · 2019 · External reference
The roles of N6-methyladenosine and its target regulatory noncoding RNAs in tumors: classification, mechanisms, and potential therapeutic implications
10.1038/s12276-023-00944-y · 2023 · External reference
Marking RNA: m6A writers, readers, and functions in arabidopsis
10.1093/jmcb/mjz085 · 2019 · External reference
Human and arabidopsis alpha-ketoglutarate-dependent dioxygenase homolog proteins-new players in important regulatory processes
10.1002/iub.2276 · 2020 · External reference
Reversible methylation of m6Am in the 5′ cap controls mRNA stability
10.1038/nature21022 · 2017 · External reference
ECT8, an mRNA m6A reader, enhances salt stress tolerance by modulating mRNA stability in arabidopsis
10.1111/ppl.70135 · 2025 · External reference
Reading m6A marks in mRNA: a potent mechanism of gene regulation in plants
10.1111/jipb.13781 · 2024 · External reference
A comprehensive review of m6A/m6Am RNA methyltransferase structures
10.1093/nar/gkab378 · 2021 · External reference
Nanopore direct RNA sequencing maps the complexity of arabidopsis mRNA processing and m6A modification
10.7554/elife.49658 · 2020 · External reference
Unravelling abiotic stress physiology in cotton (Gossypium hirsutum L.): biotechnological interventions in mitigating abiotic stress
2024 · External reference
Abiotic stress in cotton: insights into plant responses and biotechnological solutions
10.3390/agriculture14091638 · 2024 · External reference
Alternative splicing, RNA editing, and the current limits of next-generation sequencing
10.3390/genes14071386 · 2023 · External reference
Pathogen-induced m6A dynamics affect plant immunity
10.1093/plcell/koad224 · 2023 · External reference
Epigenetic stress memory: a new approach to studying cold and heat stress responses in plants
10.3389/fpls.2022.1075279 · 2022 · External reference
Multi-omics pipeline and omics-integration approach to decipher plant’s abiotic stress tolerance responses
10.3390/genes14061281 · 2023 · External reference
Mechanism of cotton resistance to abiotic stress, and recent research advances in the osmoregulation related genes
10.3389/fpls.2022.972635 · 2022 · External reference
Genome-wide identification and characterization of m6A regulatory genes in soybean: insights into evolution, miRNA interactions, and stress responses
10.1371/journal.pone.0328773 · 2025 · External reference
Dissecting the sequence and structural determinants guiding m6A deposition and evolution via inter- and intra-species hybrids
10.1186/s13059-024-03182-1 · 2024 · External reference
A review of m6A modification in plant development and potential quality improvement
10.1016/j.ijbiomac.2025.142597 · 2025 · External reference
The AlkB homolog SlALKBH10B negatively affects drought and salt tolerance in Solanum lycopersicum
10.3390/ijms25010173 · 2023 · External reference
Programmable RNA N6-methyladenosine editing with CRISPR/dCas13a in plants
10.1111/pbi.14307 · 2024 · External reference
Principles, functions, and biological implications of m6A in plants
10.1261/rna.079951.124 · 2024 · External reference
Dynamic roles for small RNAs and DNA methylation during ovule and fiber development in allotetraploid cotton
10.1371/journal.pgen.1005724 · 2015 · External reference
DNA methylation and gene expression dynamics during cotton ovule and fiber development
2014 · External reference
Transcriptome-wide m6A methylation profile reveals regulatory networks in roots of barley under cadmium stress
10.1016/j.jhazmat.2021.127140 · 2022 · External reference
Cap-specific m6Am methyltransferase PCIF1/CAPAM regulates mRNA stability of RAB23 and CNOT6 through the m6A methyltransferase activity
10.3390/cells13201689 · 2024 · External reference
The cap-specific m6A methyltransferase, PCIF1/CAPAM, is dynamically recruited to the gene promoter in a transcription-dependent manner
10.1093/jb/mvab032 · 2021 · External reference
m6Am-seq reveals the dynamic m6Am methylation in the human transcriptome
10.1038/s41467-021-25105-5 · 2021 · External reference
Genome-wide identification of m6A writers, erasers and readers in poplar 84K
10.3390/genes13061018 · 2022 · External reference
METTL3 promotes colorectal cancer progression through activating JAK1/STAT3 signaling pathway
10.1038/s41419-023-06287-w · 2023 · External reference
Knockout of SlALKBH2 weakens the DNA damage repair ability of tomato
10.1016/j.plantsci.2022.111266 · 2022 · External reference
Detection, regulation, and functions of RNA N6-methyladenosine modification in plants
10.1016/j.xplc.2023.100546 · 2023 · External reference
OsALKBH9-mediated m6A demethylation regulates tapetal PCD and pollen exine accumulation in rice
10.1111/pbi.14354 · 2024 · External reference
Strategies for RNA m6A modification application in crop improvement
10.3389/fpls.2024.1477240 · 2024 · External reference
Distinct RNA N-demethylation pathways catalyzed by nonheme iron ALKBH5 and FTO enzymes enable regulation of formaldehyde release rates
10.1073/pnas.2007349117 · 2020 · External reference
Profiling alternative 3’ untranslated regions in sorghum using RNA-seq data
10.3389/fgene.2020.556749 · 2020 · External reference
CRISPR-Cas9-mediated construction of a cotton CDPK mutant library for identification of insect-resistance genes
10.1016/j.xplc.2024.101047 · 2024 · External reference
Quantitative profiling of m6A at single base resolution across the life cycle of rice and Arabidopsis
10.1038/s41467-024-48941-7 · 2024 · External reference
Structural basis for cooperative function of Mettl3 and Mettl14 methyltransferases
10.1016/j.molcel.2016.05.041 · 2016 · External reference
Genome-wide identification and characterization of ALKB homolog gene family in wheat (Triticum aestivum L.)
2025 · External reference
Differential m6A, m6Am, and m1A demethylation mediated by FTO in cell nucleus and cytoplasm
10.1016/j.molcel.2018.08.011 · 2018 · External reference
Detection, distribution, and functions of RNA N6-methyladenosine (m6A) in plant development and environmental signal responses
10.3389/fpls.2024.1429011 · 2024 · External reference
N-methyladenosine mRNA modification regulates transcripts stability associated with cotton fiber elongation
10.1111/tpj.16274 · 2023 · External reference
Novel insights into the interaction between N6-methyladenosine modification and circular RNA
10.1016/j.omtn.2022.01.007 · 2022 · External reference
WTAP–VIRMA counteracts dsDNA binding of the m6A writer METTL3–METTL14 complex and maintains N6-adenosine methylation activity
10.1038/s41421-023-00604-5 · 2023 · External reference
Genome-wide identification and analysis of YTH gene family and its response to MeJA and salt treatment in Panax ginseng C. A. Meyer
10.1186/s12870-025-08015-2 · 2025 · External reference
Current progress in strategies to profile transcriptomic m6A modifications
10.3389/fcell.2024.1392159 · 2024 · External reference
CRISPR/dCas13(Rx) derived RNA N6-methyladenosine (m6A) dynamic modification in plant
10.1002/advs.202401118 · 2024 · External reference
Epigenomic transcriptome regulation of growth and development and stress response in Cucurbitaceae plants: The role of RNA methylation
10.3390/cimb47110938 · 2025 · External reference
N6-methyladenosine regulatory machinery in plants: composition, function and evolution
10.1111/pbi.13149 · 2019 · External reference
The barley m6A demethylase HvALKBH1B undergoes phase separation to enhance immunity to a plant rhabdovirus
10.1093/plcell/koaf210 · 2025 · External reference
Downregulation of GhALKBH10B improves drought tolerance through increasing the stability of photosynthesis related- and ABA signaling pathway genes in cotton
10.1016/j.envexpbot.2024.105687 · 2024 · External reference
Regulation of N6-methyladenosine (m6A) RNA methylation in microglia-mediated inflammation and ischemic stroke
2022 · External reference
Unique features of the m6A methylome and its response to drought stress in sea buckthorn (Hippophae rhamnoides Linn.)
10.1080/15476286.2021.1992996 · 2021 · External reference
The regulatory role of m6A modification in the maintenance and differentiation of embryonic stem cells
2024 · External reference
N6-methyladenosine mRNA methylation is important for the light response in soybean
2023 · External reference
Cap-specific terminal N6-methyladeonsine methylation of RNA mediated by PCIF1 and possible therapeutic implications
10.1016/j.gendis.2023.101181 · 2023 · External reference
m6A modification in RNA: biogenesis, functions and roles in gliomas
10.1186/s13046-020-01706-8 · 2020 · External reference
Genome-wide identification of the soybean AlkB homologue gene Family and functional characterization of GmALKBH10Bs as RNA m6A demethylases and expression patterns under abiotic stress
10.3390/plants13172491 · 2024 · External reference
Genome-wide identification of the AlkB homologs gene family, PagALKBH9B and PagALKBH10B regulated salt stress response in Populus
2022 · External reference
m6A-binding proteins: the emerging crucial performers in epigenetics
10.1186/s13045-020-00872-8 · 2020 · External reference
ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
10.1016/j.molcel.2012.10.015 · 2013 · External reference
Analysis of N6-methyladenosine reveals a new important mechanism regulating the salt tolerance of sweet sorghum
10.1016/j.plantsci.2020.110801 · 2021 · External reference
The transcriptional regulation of Arabidopsis ECT8 by ABA-responsive element-binding transcription factors in response to ABA and abiotic stresses
10.1007/s12298-025-01565-7 · 2025 · External reference
Genome-wide analysis and functional characterization of LACS gene family associated with lipid synthesis in cotton (Gossypium spp.)
10.3390/ijms24108530 · 2023 · External reference
m6A-mediated regulation of crop development and stress responses
10.1111/pbi.13792 · 2022 · External reference
METTL3 Contributes to osteosarcoma progression by increasing DANCR mRNA stability via m6A modification
10.3389/fcell.2021.784719 · 2022 · External reference
Transcriptome analysis reveals crosstalk of responsive genes to multiple abiotic stresses in cotton (Gossypium hirsutum L.)
2013 · External reference
