Research graph
References from Handles on chromosome architecture. Local targets link to admitted publications; unresolved targets remain external evidence.
Genome folding through loop extrusion by SMC complexes
10.1038/s41580-021-00349-7 · 2021 · External reference
Genome control by SMC complexes
10.1038/s41580-023-00609-8 · 2023 · External reference
Regulation of pericentromeric DNA loop size via Scc2-cohesin interaction
10.1016/j.isci.2025.112322 · 2025 · External reference
Chromosome organization by fine-tuning an ATPase
10.1101/gad.350627.123 · 2023 · External reference
Smc3 acetylation, Pds5 and Scc2 control the translocase activity that establishes cohesin-dependent chromatin loops
10.1038/s41594-022-00780-0 · 2022 · External reference
Cohesin cofactor dosage sets the rate of loop extrusion, rendering genome folding tunable yet vulnerable to genetic disruption
10.1016/j.molcel.2026.03.037 · 2026 · External reference
PDS5 proteins control genome architecture by limiting the lifetime of cohesin-NIPBL complexes
10.1016/j.molcel.2026.03.025 · 2026 · External reference
