Research graph
References from CPT1A alters granulosa cell proliferation and steroidogenic activity in association with fatty acid oxidation during goat follicular development. Local targets link to admitted publications; unresolved targets remain external evidence.
Improvement in early antral follicle development and gene expression modulation prior to follicle aspiration in bovine cumulus-oocyte complexes by equine chorionic gonadotropin
10.1016/j.theriogenology.2021.07.003 · 2021 · External reference
HIF1A regulates follicular atresia through O-GlcNAcylation-mediated VEZF1/ET-1/FOXO1/BAX signaling in porcine granulosa cells
10.1186/s40104-025-01263-0 · 2025 · External reference
COL1A1 promotes cell proliferation, cell cycle progression, and anoikis resistance in granulosa cells of chicken pre-ovulatory follicles
2025 · External reference
miRNA-novel-216 regulated fatty acid composition and progesterone synthesis in goat granulosa cells by targeting the TPD52
10.1530/rep-24-0231 · 2025 · External reference
Adiponectin preserves follicles through ADIPOR1/ADIPOR2-driven fatty acid metabolism
10.1016/j.molmet.2026.102392 · 2026 · External reference
CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma
10.1038/s41419-022-04730-y · 2022 · External reference
Inhibiting TRIM21 neddylation rejuvenates oocyte quality in PCOS by regulating ubiquitination of CPT1A
2026 · External reference
Placental-derived mesenchymal stem cells triggers lipid metabolism in a rat model thioacetamide-induced ovarian disease via increased CPT1A expression for mitochondrial dynamics
10.3390/cells14241932 · 2025 · External reference
Dietary supplementation with raspberry or strawberry seed oil impacts folliculogenesis, hormonal parameters and the fatty acid profile in the juvenile rabbit ovary
10.3390/ani16101528 · 2026 · External reference
Dapagliflozin alleviated obesity-related follicular development dysfunction by regulating glucose metabolism and mitochondria function in granulosa cells
10.1016/j.jnutbio.2025.110126 · 2026 · External reference
CPT1a expression is a critical cardioprotective response to pathological stress that enables rescue by gene transfer
10.1161/circresaha.125.327403 · 2026 · External reference
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation
10.1016/j.devcel.2025.04.004 · 2025 · External reference
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer
10.1038/s41392-024-01772-w · 2024 · External reference
Leonurine restrains granulosa cell ferroptosis through SLC7A11/GPX4 axis to promote the treatment of polycystic ovary syndrome
10.1016/j.freeradbiomed.2024.11.021 · 2025 · External reference
Ferroptosis and sterol biosynthesis dysregulation in granulosa cells of patients with diminished ovarian reserve
10.3390/antiox14060749 · 2025 · External reference
Deoxynivalenol impairs ovarian function by triggering ferroptosis in granulosa cells through GPX2 inhibition and oxidative stress
10.1021/acs.jafc.6c02013 · 2026 · External reference
Role and mechanism of palmitic acid-regulated palmitoylation modification of SEC63 protein during endoplasmic reticulum stress in human ovarian granulosa tumor cells (KGN)
10.1186/s13048-026-01998-y · 2026 · External reference
Autophagy is involved in granulosa cell death and follicular atresia in ewe ovaries
10.1016/j.theriogenology.2024.06.024 · 2024 · External reference
SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1
10.1007/s00018-025-05797-4 · 2025 · External reference
Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation
10.1093/procel/pwad065 · 2024 · External reference
Interconnected cell death pathways: central mechanisms and therapeutic targets in impaired follicular development of polycystic ovary syndrome
10.1186/s13048-026-02054-5 · 2026 · External reference
Oxidative stress and SIRT1-Nrf2 anti-ferroptotic pathways in granulosa cells: a molecular key to follicular atresia and ovarian aging
10.3390/ijms27020950 · 2026 · External reference
Palmitic acid fuels triple-negative breast cancer through metadherin-dependent fatty acid β-oxidation: relevance to high fat diet-induced breast cancer progression
10.1016/j.cellsig.2025.112320 · 2026 · External reference
FABP5 confers resistance to drug-induced ROS toxicity in cervical cancer cell lines by suppressing the PPARγ/CPT1A signaling pathway
10.1007/s12672-026-05268-7 · 2026 · External reference
Inhibition of CPT1A activates the cGAS/STING pathway to enhance neutrophil-mediated tumor abrogation in triple-negative breast cancer
10.1016/j.canlet.2025.217991 · 2025 · External reference
Loss of Cpt1a results in elevated glucose-fueled mitochondrial oxidative phosphorylation and defective hematopoietic stem cells
10.1172/jci184069 · 2025 · External reference
Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis
10.7150/thno.84921 · 2023 · External reference
Deficiency of mitochondrial fatty acid enzyme, CPT1A, underlies airway epithelial barrier dysfunction in severe asthma
10.1111/all.70428 · 2026 · External reference
Eicosapentaenoic acid improves porcine oocyte cytoplasmic maturation and developmental competence via antioxidant and mitochondrial regulatory mechanisms
10.3390/antiox15010137 · 2026 · External reference
Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice
10.3389/fcell.2025.1683028 · 2025 · External reference
RAB5A regulates cell proliferation and lipid metabolism by modulating mitochondrial ROS via AMPK signaling pathway in ovarian granulosa cells
10.1016/j.redox.2026.104183 · 2026 · External reference
Expression variation of CPT1A induces lipid reconstruction in goat intramuscular precursor adipocytes
10.3390/ijms241713415 · 2023 · External reference
Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer
10.1038/s42003-023-04993-x · 2023 · External reference
Mdivi-1 promotes steroidogenesis in granulosa cells by inhibiting mitochondrial fission
10.1016/j.mce.2025.112606 · 2025 · External reference
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin
10.1093/hropen/hoae002 · 2024 · External reference
Autophagy-dependent versus autophagy-independent ferroptosis
10.1016/j.tcb.2025.01.005 · 2025 · External reference
miR-26a-Targeting SLC7A11 regulates erastin-induced granulosa cell ferroptosis
10.3390/antiox14111283 · 2025 · External reference
SOX3 facilitates granulosa cell proliferation and suppresses cell apoptosis through modulating PI3K/AKT pathway by targeting SPP1
10.1007/s00018-025-05797-4 · ExternalCitation · doi-reference
FABP5 confers resistance to drug-induced ROS toxicity in cervical cancer cell lines by suppressing the PPARγ/CPT1A signaling pathway
10.1007/s12672-026-05268-7 · ExternalCitation · doi-reference
Inhibition of CPT1A activates the cGAS/STING pathway to enhance neutrophil-mediated tumor abrogation in triple-negative breast cancer
10.1016/j.canlet.2025.217991 · ExternalCitation · doi-reference
Palmitic acid fuels triple-negative breast cancer through metadherin-dependent fatty acid β-oxidation: relevance to high fat diet-induced breast cancer progression
10.1016/j.cellsig.2025.112320 · ExternalCitation · doi-reference
Mitochondrial CCN1 drives ferroptosis via fatty acid β-oxidation
10.1016/j.devcel.2025.04.004 · ExternalCitation · doi-reference
Leonurine restrains granulosa cell ferroptosis through SLC7A11/GPX4 axis to promote the treatment of polycystic ovary syndrome
10.1016/j.freeradbiomed.2024.11.021 · ExternalCitation · doi-reference
Dapagliflozin alleviated obesity-related follicular development dysfunction by regulating glucose metabolism and mitochondria function in granulosa cells
10.1016/j.jnutbio.2025.110126 · ExternalCitation · doi-reference
Mdivi-1 promotes steroidogenesis in granulosa cells by inhibiting mitochondrial fission
10.1016/j.mce.2025.112606 · ExternalCitation · doi-reference
Adiponectin preserves follicles through ADIPOR1/ADIPOR2-driven fatty acid metabolism
10.1016/j.molmet.2026.102392 · ExternalCitation · doi-reference
RAB5A regulates cell proliferation and lipid metabolism by modulating mitochondrial ROS via AMPK signaling pathway in ovarian granulosa cells
10.1016/j.redox.2026.104183 · ExternalCitation · doi-reference
Autophagy-dependent versus autophagy-independent ferroptosis
10.1016/j.tcb.2025.01.005 · ExternalCitation · doi-reference
Improvement in early antral follicle development and gene expression modulation prior to follicle aspiration in bovine cumulus-oocyte complexes by equine chorionic gonadotropin
10.1016/j.theriogenology.2021.07.003 · ExternalCitation · doi-reference
Autophagy is involved in granulosa cell death and follicular atresia in ewe ovaries
10.1016/j.theriogenology.2024.06.024 · ExternalCitation · doi-reference
Deoxynivalenol impairs ovarian function by triggering ferroptosis in granulosa cells through GPX2 inhibition and oxidative stress
10.1021/acs.jafc.6c02013 · ExternalCitation · doi-reference
Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer
10.1038/s41392-024-01772-w · ExternalCitation · doi-reference
CPT1A-mediated fatty acid oxidation promotes cell proliferation via nucleoside metabolism in nasopharyngeal carcinoma
10.1038/s41419-022-04730-y · ExternalCitation · doi-reference
Carnitine palmitoyltransferase 1A promotes mitochondrial fission by enhancing MFF succinylation in ovarian cancer
10.1038/s42003-023-04993-x · ExternalCitation · doi-reference
Attenuation of palmitic acid-induced lysyl oxidase overexpression in the ovary contributes to the improvement of ovulation in obesity by metformin
10.1093/hropen/hoae002 · ExternalCitation · doi-reference
Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation
10.1093/procel/pwad065 · ExternalCitation · doi-reference
Deficiency of mitochondrial fatty acid enzyme, CPT1A, underlies airway epithelial barrier dysfunction in severe asthma
10.1111/all.70428 · ExternalCitation · doi-reference
CPT1a expression is a critical cardioprotective response to pathological stress that enables rescue by gene transfer
10.1161/circresaha.125.327403 · ExternalCitation · doi-reference
Loss of Cpt1a results in elevated glucose-fueled mitochondrial oxidative phosphorylation and defective hematopoietic stem cells
10.1172/jci184069 · ExternalCitation · doi-reference
Role and mechanism of palmitic acid-regulated palmitoylation modification of SEC63 protein during endoplasmic reticulum stress in human ovarian granulosa tumor cells (KGN)
10.1186/s13048-026-01998-y · ExternalCitation · doi-reference
Interconnected cell death pathways: central mechanisms and therapeutic targets in impaired follicular development of polycystic ovary syndrome
10.1186/s13048-026-02054-5 · ExternalCitation · doi-reference
HIF1A regulates follicular atresia through O-GlcNAcylation-mediated VEZF1/ET-1/FOXO1/BAX signaling in porcine granulosa cells
10.1186/s40104-025-01263-0 · ExternalCitation · doi-reference
miRNA-novel-216 regulated fatty acid composition and progesterone synthesis in goat granulosa cells by targeting the TPD52
10.1530/rep-24-0231 · ExternalCitation · doi-reference
Long-chain fatty acid β-oxidation regulates embryonic development by H3K18 acetylation in mice
10.3389/fcell.2025.1683028 · ExternalCitation · doi-reference
Dietary supplementation with raspberry or strawberry seed oil impacts folliculogenesis, hormonal parameters and the fatty acid profile in the juvenile rabbit ovary
10.3390/ani16101528 · ExternalCitation · doi-reference
Ferroptosis and sterol biosynthesis dysregulation in granulosa cells of patients with diminished ovarian reserve
10.3390/antiox14060749 · ExternalCitation · doi-reference
miR-26a-Targeting SLC7A11 regulates erastin-induced granulosa cell ferroptosis
10.3390/antiox14111283 · ExternalCitation · doi-reference
Eicosapentaenoic acid improves porcine oocyte cytoplasmic maturation and developmental competence via antioxidant and mitochondrial regulatory mechanisms
10.3390/antiox15010137 · ExternalCitation · doi-reference
Placental-derived mesenchymal stem cells triggers lipid metabolism in a rat model thioacetamide-induced ovarian disease via increased CPT1A expression for mitochondrial dynamics
10.3390/cells14241932 · ExternalCitation · doi-reference
Expression variation of CPT1A induces lipid reconstruction in goat intramuscular precursor adipocytes
10.3390/ijms241713415 · ExternalCitation · doi-reference
Oxidative stress and SIRT1-Nrf2 anti-ferroptotic pathways in granulosa cells: a molecular key to follicular atresia and ovarian aging
10.3390/ijms27020950 · ExternalCitation · doi-reference
Restoration of CPT1A-mediated fatty acid oxidation in mesothelial cells protects against peritoneal fibrosis
10.7150/thno.84921 · ExternalCitation · doi-reference
