Research graph
References from Heated cigarette smoke extract induces oxidative stress and remodels lipid signatures of the extracellular vesicle released by bronchial epithelial cells. Local targets link to admitted publications; unresolved targets remain external evidence.
LipidOne 2.0: a web tool for discovering biological meanings hidden in lipidomic data
10.1002/cpz1.70009 · 2024 · External reference
The effect of emerging tobacco related products and their toxic constituents on thrombosis
10.1016/j.lfs.2021.120255 · 2022 · External reference
Whispers in the Lungs: Small Extracellular Vesicles in Lung Cancer and COPD Crosstalk
10.3390/cancers17101612 · 2025 · External reference
Vascular stress markers following inhalation of heated tobacco products: a study on extracellular vesicles
10.1007/s12012-024-09934-6 · 2025 · External reference
Heat-not-burn tobacco cigarettes: smoke by any other name
10.1001/jamainternmed.2017.1419 · 2017 · External reference
Comparison of chemicals in mainstream smoke in heat-not-burn tobacco and combustion cigarettes
10.7888/juoeh.39.201 · 2017 · External reference
Extracellular vesicles released in response to respiratory exposures: implications for chronic disease
10.1080/10937404.2018.1466380 · 2018 · External reference
Do alternative tobacco products induce less adverse respiratory risk than cigarettes?
10.1186/s12931-023-02568-2 · 2023 · External reference
Plasmalogens and chronic inflammatory diseases
10.3389/fphys.2021.730829 · 2021 · External reference
Characterization of Nanovesicles isolated from olive vegetation water
10.3390/foods13060835 · 2024 · External reference
Lipotoxic stress alters the membrane lipid profile of extracellular vesicles released by Huh-7 hepatocarcinoma cells
10.1038/s41598-021-84268-9 · 2021 · External reference
Extracellular vesicles released by fibroblasts undergoing H-Ras induced senescence show changes in lipid profile
10.1371/journal.pone.0188840 · 2017 · External reference
Endothelial-derived extracellular vesicles associated with electronic cigarette use impair cerebral microvascular cell function
10.1152/japplphysiol.00243.2023 · 2023 · External reference
Phospholipid fatty acid remodeling and carbonylated protein increase in extracellular vesicles released by airway epithelial cells exposed to cigarette smoke extract
10.1016/j.ejcb.2022.151285 · 2023 · External reference
Alterations in the transcriptome of human primary bronchial epithelial cells exposed to emissions from a heated tobacco product
10.1016/j.bbagen.2025.130869 · 2025 · External reference
Heated tobacco product emissions induce DNA damage in human bronchial epithelial cells via radical formation
10.1080/10715762.2025.2521633 · 2025 · External reference
Comparison of the chemical composition of aerosols from heated tobacco products, electronic cigarettes and tobacco cigarettes and their toxic impacts on the human bronchial epithelial BEAS-2B cells
10.1016/j.jhazmat.2020.123417 · 2021 · External reference
Environmental exposures and extracellular vesicles: indicators of systemic effects and human disease
10.1007/s40572-022-00357-5 · 2022 · External reference
Circulating extracellular microvesicles associated with electronic cigarette use increase endothelial cell inflammation and reduce nitric oxide production
10.1113/ep091715 · 2024 · External reference
Nicotine and novel tobacco products drive adverse cardiac remodeling and dysfunction in preclinical studies
10.3389/fcvm.2022.993617 · 2022 · External reference
Genotoxicity and cytotoxicity evaluation of a heat-not-burn product
10.1016/j.mrgentox.2024.503784 · 2024 · External reference
Evaluating the risks of heated tobacco products: toxicological effects on two selected respiratory bacteria and human lung cells
10.3390/toxics13020070 · 2025 · External reference
A scoping review of the toxicity and health impact of IQOS
10.18332/tid/188867 · 2024 · External reference
Potential harm of IQOS smoke to rat liver
10.3390/ijms241512462 · 2023 · External reference
Heat-not-burn technology affects plasma testosterone levels and markers of inflammation, oxidative stress in the testes of rats
2024 · External reference
Cigarette smoke, but not novel tobacco vapor products, causes epigenetic disruption and cell apoptosis
2020 · External reference
Comparison of cytotoxicity of cigarette smoke extract derived from heat-not-burn and combustion cigarettes in human vascular endothelial cells
10.1016/j.jphs.2021.07.005 · 2021 · External reference
Use of cigarettes and heated tobacco products during pregnancy and maternal-fetal outcomes: a retrospective, monocentric study
10.1007/s00404-023-07101-w · 2024 · External reference
Heat-Not-Burn cigarette induces oxidative stress response in primary rat alveolar epithelial cells
10.1371/journal.pone.0242789 · 2020 · External reference
The impact of heat-not-burn, e-cigarettes, and cigarettes on small airway function
10.1177/1179173x241271551 · 2024 · External reference
Nicotine in E-cigarette aerosol may lead to pulmonary inflammation
10.1016/j.rmed.2025.108101 · 2025 · External reference
Heat-not-burn tobacco aerosols induce immune dysregulation and barrier disruption comparable to conventional cigarettes
2025 · External reference
A new ingenious enemy: heat-not-burn products
10.1177/1179173x221076419 · 2022 · External reference
IQOS–a heat-not-burn (HnB) tobacco product–chemical composition and possible impact on oxidative stress and inflammatory response. A systematic review
10.1080/15376516.2019.1669245 · 2020 · External reference
Metabolomics provides novel insights into the potential toxicity associated with heated tobacco products, electronic cigarettes, and tobacco cigarettes on human bronchial epithelial BEAS-2B Cells
10.3390/toxics12020128 · 2024 · External reference
Vaping/e-cigarette-induced pulmonary extracellular vesicles contribute to exacerbated cardiomyocyte impairment through the translocation of ERK5
10.1016/j.lfs.2024.123195 · 2024 · External reference
Molecular lipidomics of exosomes released by PC-3 prostate cancer cells
10.1016/j.bbalip.2013.04.011 · 2013 · External reference
Role of phosphatidylserine-derived negative surface charges in the recognition and uptake of intravenously injected B16BL6-derived exosomes by macrophages
10.1016/j.xphs.2016.07.022 · 2017 · External reference
Electronic cigarettes containing nicotine increase endothelial and platelet derived extracellular vesicles in healthy volunteers
10.1016/j.atherosclerosis.2020.02.010 · 2020 · External reference
E-liquid exposure induces bladder cancer cells to release extracellular vesicles that promote non-malignant urothelial cell transformation
10.1038/s41598-022-27165-z · 2023 · External reference
Effect of environmental exposures on cancer risk: Emerging role of non-coding RNA shuttled by extracellular vesicles
10.1016/j.envint.2023.108255 · 2023 · External reference
Cytotoxic, genotoxic, and toxicogenomic effects of heated tobacco products and cigarette smoke in human primary keratinocytes
10.18332/tid/152510 · 2022 · External reference
Unburned tobacco smoke affects neuroinflammation-related pathways in the rat mesolimbic system
10.3390/ijms25105259 · 2024 · External reference
Exposure to aerosol extract from heated tobacco products causes a drastic decrease of glutathione and protein carbonylation in human lung epithelial cells
10.1016/j.bbrc.2021.12.004 · 2022 · External reference
Whole cigarette smoke condensates of heated tobacco products disrupt cell adhesion and induce anoikis in human bronchial epithelial cells
2025 · External reference
Acute effects of a heat-not-burn tobacco product on pulmonary function
2020 · External reference
LC/MS lipid profiling from human serum: a new method for global lipid extraction
10.1007/s00216-014-8255-0 · 2014 · External reference
Heated tobacco products: emerging health outcomes and insights into oxidative stress and pro-inflammatory-driving mechanisms
10.3390/antiox15010008 · 2025 · External reference
Heat not burn tobacco product—a new global trend: Impact of heat-not-burn tobacco products on public health, a systematic review
10.3390/ijerph17020409 · 2020 · External reference
The potential roles of extracellular vesicles in cigarette smoke-associated diseases
10.1155/2018/4692081 · 2018 · External reference
The effects of dual IQOS and cigarette smoke exposure on airway epithelial cells: implications for lung health and respiratory disease pathogenesis
10.1183/23120541.00558-2022 · 2023 · External reference
Extracellular vesicles from human airway basal cells respond to cigarette smoke extract and affect vascular endothelial cells
10.1038/s41598-021-85534-6 · 2021 · External reference
Should IQOS emissions be considered as smoke and harmful to health? A Review of the Chemical Evidence
10.1021/acsomega.2c01527 · 2022 · External reference
Heated tobacco products: insights into composition and toxicity
10.3390/toxics11080667 · 2023 · External reference
Unburned tobacco cigarette smoke alters rat ultrastructural lung airways and DNA
10.1093/ntr/ntab108 · 2021 · External reference
Evaluation of toxicity of heated tobacco products aerosol and cigarette smoke to BEAS-2B cells based on 3D biomimetic chip model
10.1016/j.tiv.2023.105708 · 2024 · External reference
Minimal information for studies of extracellular vesicles (MISEV2023): from basic to advanced approaches
10.1002/jev2.12404 · 2024 · External reference
Comparison of IQOS (heated tobacco) and cigarette smoking on cardiac functions by two-dimensional speckle tracking echocardiography
10.1016/j.taap.2021.115575 · 2021 · External reference
Effects of fetal exposure to heat-not-burn tobacco on testicular function in male offspring
10.1248/bpb.b20-00390 · 2020 · External reference
Impact of electronic cigarettes, heated tobacco products and conventional cigarettes on the generation of oxidative stress and genetic and epigenetic lesions in human bronchial Epithelial BEAS-2B Cells
10.3390/toxics11100847 · 2023 · External reference
Impact of smoking on salivary lipid profile and oxidative stress in young adults: a comparative analysis between traditional cigarettes, e-cigarettes, and heat-not-burn products
2024 · External reference
Exposure to heated tobacco products and adverse health effects, a systematic review
10.3390/ijerph18126651 · 2021 · External reference
The health effects of heated tobacco product use-a narrative review
10.3390/healthcare13162042 · 2025 · External reference
