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References from Genotoxic and cytokine-associated responses to benzo[g,h,i]perylene and benzo[b]fluoranthene in a human lung co-culture model at the pseudo-air–liquid interface. Local targets link to admitted publications; unresolved targets remain external evidence.
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Benzo[b]fluoranthene induced oxidative stress and apoptosis in human airway epithelial cells via mitochondrial disruption
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Unresolved reference
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Genotoxic mode of action predictions from a multiplexed flow cytometric assay and a machine learning approach
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Silico approach in the evaluation of pro-inflammatory potential of polycyclic aromatic hydrocarbons and volatile organic compounds through binding affinity to the human toll-like receptor 4
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Cytotoxic and genotoxic effects of Benzo[ghi]perylene on the human bronchial cell line NL-20
2019 · External reference
Toxicity effect of polycyclic aromatic hydrocarbon on the micronucleus and red blood cell of tilapia guineensis
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Humoral immunosuppression of exposure to polycyclic aromatic hydrocarbons and the roles of oxidative stress and inflammation
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Polycyclic aromatic hydrocarbons and PAH-related DNA adducts
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Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells
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External reference
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10.1016/j.taap.2015.11.010 · 2016 · External reference
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10.3390/atmos15121525 · 2024 · External reference
Benzo[b]fluoranthene damages coronary artery and affects atherosclerosis markers in mice and umbilical vein endothelial cells
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Polycyclic aromatic hydrocarbon and its effects on human health: An overeview
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Dynamic fluid flow exacerbates the (pro-)inflammatory effects of aerosolised engineered nanomaterials in vitro
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Benzo(ghi)perylene (BgP) a black tattoo ingredient induced skin toxicity via direct and indirect mode of DNA damage under UVA irradiation
10.1016/j.cbi.2023.110508 · 2023 · External reference
Systematic review of exposure to polycyclic aromatic hydrocarbons and obstructive lung disease
10.5696/2156-9614-11.31.210903 · 2021 · External reference
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2019 · External reference
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Dose-related mutagenic and clastogenic effects of benzo[b]fluoranthene in mouse somatic tissues detected by duplex sequencing and the micronucleus assay
2024 · External reference
Metabolic activation of polycyclic aromatic hydrocarbons to carcinogens by cytochromes P450 1A1 and 1B1
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Modulation of gene expression and DNA adduct formation in HepG2 cells by polycyclic aromatic hydrocarbons with different carcinogenic potencies
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10.3390/cells9122557 · 2020 · External reference
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Toxic effect of polycyclic aromatic hydrocarbons (PAHs) on co-culture model of human alveolar epithelial cells (A549) and macrophages (THP-1)
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Developmental exposure to polycyclic aromatic hydrocarbons ( PAHs): focus on benzo [ a] pyrene neurotoxicity
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Comparative genotoxic potential of 27 polycyclic aromatic hydrocarbons in three human cell lines
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DNA adducts formation and induction of apoptosis in rat liver epithelial “stem-like” cells exposed to carcinogenic polycyclic aromatic hydrocarbons
2008 · External reference
γH2AX as a marker of DNA double strand breaks and genomic instability in human population studies
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DNA adducts and cancer risk in prospective studies: a pooled analysis and a meta-analysis
10.1093/carcin/bgm286 · 2008 · External reference
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2020 · External reference
H2AX phosphorylation as a genotoxicity endpoint
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Unresolved reference
2026 · External reference
Metabolic activation of polycyclic and heterocyclic aromatic hydrocarbons and DNA damage: a review
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Effect of polycyclic aromatic hydrocarbons on immunity
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CHK2 kinase in the DNA damage response and beyond
10.1093/jmcb/mju045 · 2014 · External reference
Benzo[ghi]perylene activates the AHR pathway to exert biological effects on the NL-20 human bronchial cell line
10.1016/j.toxlet.2016.05.023 · 2016 · External reference
Benzo[ghi]perylene induces cellular dormancy signaling and endoplasmic reticulum stress in NL-20 human bronchial epithelial cells
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The occurrence of 16 EPA PAHs in food – a review
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Maternal exposure to polycyclic aromatic hydrocarbons and visual developmental outcomes in early childhood
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