Research graph
References from Sub-acute dihydroxyacetone exposure alters mitochondria and induces cardiac strain. Local targets link to admitted publications; unresolved targets remain external evidence.
Frequency of use and smoking status of U.S. adolescent E-cigarette users in 2015
10.1016/j.amepre.2018.03.003 · 2018 · External reference
Electronic cigarette use among adults in the United States, 2019–2023
2025 · External reference
Unresolved reference
External reference
Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction
10.3389/fphar.2022.1012723 · 2022 · External reference
Mitochondrial dysfunction induced by E-cigarettes
10.1016/j.tox.2025.154339 · 2026 · External reference
Reactive oxygen species, mitochondrial membrane potential, and cellular membrane potential are predictors of E-liquid induced cellular toxicity
10.1093/ntr/ntaa177 · 2020 · External reference
Dihydroxyacetone levels in electronic cigarettes: Wick temperature and toxin formation
10.1080/02786826.2018.1424316 · 2018 · External reference
Ultrasonic cigarettes: chemicals and cytotoxicity are similar to heated-coil pod-style electronic cigarettes
10.1021/acs.chemrestox.4c00085 · 2024 · External reference
Chemical constituents involved in E-cigarette, or vaping product use-associated lung injury (EVALI)
10.3390/toxics8020025 · 2020 · External reference
Characterizing the chemical landscape in commercial E-cigarette liquids and aerosols by liquid chromatography-high-resolution mass spectrometry
10.1021/acs.chemrestox.1c00253 · 2021 · External reference
A tipping point in dihydroxyacetone exposure: mitochondrial stress and metabolic reprogramming alter survival in rat cardiomyocytes H9c2 cells
10.1016/j.cbi.2024.110991 · 2024 · External reference
Acute exposure to dihydroxyacetone promotes genotoxicity and chromosomal instability in lung, cardiac, and liver cell models
10.1093/toxsci/kfae075 · 2024 · External reference
Dihydroxyacetone suppresses mTOR nutrient signaling and induces mitochondrial stress in liver cells
10.1371/journal.pone.0278516 · 2022 · External reference
Dihydroxyacetone exposure alters NAD(P)H and induces mitochondrial stress and autophagy in HEK293T cells
10.1021/acs.chemrestox.9b00230 · 2019 · External reference
Dihydroxyacetone decreases the dATP pool, inducing replication stress and genomic instability in BEAS-2B cells
10.1016/j.jbc.2025.110876 · 2025 · External reference
Inhalation exposure to dihydroxyacetone promotes lung injury and pulmonary fibrosis in A/J mice
2025 · External reference
Measurement of electronic cigarette frequency of use among smokers participating in a randomized controlled trial
10.1093/ntr/nty233 · 2020 · External reference
A cross-category puffing topography, mouth level exposure and consumption study among Italian users of tobacco and nicotine products
10.1038/s41598-019-55410-5 · 2020 · External reference
Unresolved reference
External reference
The combination of propylene glycol and vegetable glycerin e-cigarette aerosols induces airway inflammation and mucus hyperconcentration
10.1038/s41598-024-52317-8 · 2024 · External reference
Examining daily electronic cigarette puff topography among established and nonestablished cigarette smokers in their natural environment
10.1093/ntr/ntx222 · 2018 · External reference
Broad spectrum detection of DNA damage by repair assisted damage detection (RADD)
10.1016/j.dnarep.2018.04.007 · 2018 · External reference
DNA damage measurements within tissue samples with repair assisted damage detection (RADD)
10.1016/j.crbiot.2019.11.001 · 2019 · External reference
A simple solution for antibody signal enhancement in immunofluorescence and triple immunogold assays
10.1007/s00418-016-1447-2 · 2016 · External reference
Staining of skin with dihydroxyacetone
10.1126/science.132.3431.894 · 1960 · External reference
Biochemical effects of dihydroxyacetone
10.1038/jid.1961.137 · 1961 · External reference
Unresolved reference
External reference
The sunless tanning agent dihydroxyacetone induces stress response gene expression and signaling in cultured human keratinocytes and reconstructed epidermis
10.1016/j.redox.2020.101594 · 2020 · External reference
Dihydroxyacetone, the active browning ingredient in sunless tanning lotions, induces DNA damage, cell-cycle block and apoptosis in cultured HaCaT keratinocytes
10.1016/j.mrgentox.2004.03.002 · 2004 · External reference
Cytotoxic, genotoxic, and toxicogenomic effects of dihydroxyacetone in human primary keratinocytes
10.1080/15569527.2021.1931877 · 2021 · External reference
Assessing the respiratory toxicity of dihydroxyacetone using an in vitro human airway epithelial tissue model
10.1016/j.tiv.2019.04.007 · 2019 · External reference
Electronic cigarette use intensity measurement challenges and regulatory implications
10.1136/tobaccocontrol-2021-056483 · 2023 · External reference
E-cigarettes and their lone constituents induce cardiac arrhythmia and conduction defects in mice
10.1038/s41467-022-33203-1 · 2022 · External reference
Influence of e-cigarettes and their constituents on cardiac rhythm and arrhythmias
10.1152/ajpheart.00263.2025 · 2026 · External reference
Effects of e-cigarettes and vaping devices on cardiac and pulmonary physiology
10.1113/jp279754 · 2020 · External reference
Impact of nicotine-free electronic cigarettes on cardiovascular health: a systematic review
10.3390/jcm14248717 · 2025 · External reference
Sex differences in the adverse effects of nicotine-free E-cigarettes on myocardial oxygen supply and demand balance: a preclinical rat study
10.1161/jaha.125.046489 · 2026 · External reference
Monitoring acute metabolic changes in the liver and kidneys induced by fructose and glucose using hyperpolarized [2–13 C]dihydroxyacetone
10.1002/mrm.26525 · 2017 · External reference
Real-time detection of hepatic gluconeogenic and glycogenolytic states using hyperpolarized [2–13 C]dihydroxyacetone
10.1074/jbc.m114.613265 · 2014 · External reference
Myocardial collagen remodeling in pressure overload hypertrophy. A case for interstitial heart disease
10.1093/ajh/2.12.931 · 1989 · External reference
Unresolved reference
2026 · External reference
Short-term e-cigarette vapour exposure causes vascular oxidative stress and dysfunction: evidence for a close connection to brain damage and a key role of the phagocytic NADPH oxidase (NOX-2)
10.1093/eurheartj/ehz772 · 2019 · External reference
Characteristics of e-cigarette use behaviors among US youth, 2020
10.1001/jamanetworkopen.2021.11336 · 2021 · External reference
