Research graph
References from The Implications of Hyponitroxia in Cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Nitric oxide: physiology, pathophysiology, and pharmacology
10.1016/s0031-6997(25)06663-3 · 1991 · External reference
Is Nitric Oxide (NO) the Last Word in Radiosensitization? A Review
10.1593/tlo.11307 · 2012 · External reference
Candidate pathways linking inducible nitric oxide synthase to a basal-like transcription pattern and tumor progression in human breast cancer
10.4161/cc.10.4.14864 · 2011 · External reference
Enzymatic function of nitric oxide synthases
10.1016/s0008-6363(99)00115-7 · 1999 · External reference
Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1
10.1073/pnas.0502979102 · 2005 · External reference
The role of nitric oxide in tumour progression
10.1038/nrc1910 · 2006 · External reference
Selective expression of inducible nitric oxide synthase in human prostate carcinoma
10.1002/(sici)1097-0142(19980515)82:10<1897::aid-cncr12>3.0.co;2-o · 1998 · External reference
Nitric oxide synthase activity in human lung cancer
10.1111/j.1349-7006.1997.tb00348.x · 1997 · External reference
Significance of nitric oxide in carcinogenesis, tumor progression and cancer therapy
10.1023/a:1005963400984 · 1998 · External reference
Hormesis is central to toxicology, pharmacology and risk assessment
10.1177/0960327109363973 · 2010 · External reference
The role of nitric oxide (NO) in stability regulation of hypoxia inducible factor-1α (HIF-1α)
10.2174/0929867033457746 · 2003 · External reference
Nitric oxide modulates oxygen sensing by hypoxia-inducible factor 1-dependent induction of prolyl hydroxylase 2
10.1074/jbc.m607065200 · 2007 · External reference
Oxygen tension regulates the nitric oxide pathway: physiological role in penile erection
10.1172/jci116220 · 1993 · External reference
Nitric oxide-mediated regulation of chemosensitivity in cancer cells
10.1093/jnci/93.24.1879 · 2001 · External reference
Guanylyl cyclases and signaling by cyclic GMP
10.1016/s0031-6997(24)01457-1 · 2000 · External reference
Nitric oxide: NO apoptosis or turning it ON?
10.1038/sj.cdd.4401261 · 2003 · External reference
Hypoxia-reduced nitric oxide synthase activity is partially explained by higher arginase-2 activity and cellular redistribution in human umbilical vein endothelium
10.1016/j.placenta.2011.09.003 · 2011 · External reference
10.1593/tlo.10208 · 2010 · Admitted local publication
Mechanism of hypoxia-induced NF-κB
10.1128/mcb.00409-10 · 2010 · External reference
Nitric oxide as a radiosensitizer: evidence for an intrinsic role in addition to its effect on oxygen delivery and consumption
10.1002/ijc.20046 · 2004 · External reference
Beyond antiangiogenesis: vascular modulation as an anticancer therapy—a review
10.1593/tlo.12118 · 2012 · External reference
Nitric oxide, a double edged sword in cancer biology: searching for therapeutic opportunities
10.1002/med.20092 · 2007 · External reference
Oxidative chemistry of nitric oxide: the roles of superoxide, peroxynitrite, and carbon dioxide
10.1016/s0891-5849(98)00095-1 · 1998 · External reference
Transfection with the inducible nitric oxide synthase gene suppresses tumorigenicity and abrogates metastasis by K-1735 murine melanoma cells
10.1084/jem.181.4.1333 · 1995 · External reference
Decreased activity of scavenger enzymes in human hepatocellular carcinoma, but not in liver metastases
10.1007/bf02593907 · 1994 · External reference
Oxidative stress, tumor microenvironment, and metabolic reprogramming: a diabolic liaison
10.1155/2012/762825 · 2012 · External reference
Oxidative stress and lipid peroxidation products in cancer progression and therapy
2012 · External reference
Perivascular nitric oxide gradients normalize tumor vasculature
10.1038/nm1730 · 2008 · External reference
Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling
10.1172/jci1699 · 1998 · External reference
Nitric oxide-mediated epigenetic mechanisms in developing neurons
10.4161/cc.8.5.7805 · 2009 · External reference
Nitric oxide modifies global histone methylation by inhibiting Jumonji C domain-containing demethylases
10.1074/jbc.m112.432294 · 2013 · External reference
NO sparks off chromatin: tales of a multifaceted epigenetic regulator
10.1016/j.pharmthera.2009.05.003 · 2009 · External reference
Epigenetic regulation of vascular endothelial gene expression
10.1161/circresaha.107.171025 · 2008 · External reference
Ecological therapy for cancer: defining tumors using an ecosystem paradigm suggests new opportunities for novel cancer treatments
10.1593/tlo.08178 · 2008 · External reference
Methylation-dependent gene silencing induced by interleukin 1β via nitric oxide production
10.1084/jem.190.11.1595 · 1999 · External reference
Activation of p53-p21waf1 pathway in response to disruption of cell-matrix interactions
10.1074/jbc.272.46.29091 · 1997 · External reference
DNA damage is able to induce senescence in tumor cells in vitro and in vivo
2002 · External reference
Therapy-induced senescence in cancer
10.1093/jnci/djq364 · 2010 · External reference
The role of nitric oxide in the regulation of adaptive immune responses
10.1016/s0213-9626(08)70058-1 · 2008 · External reference
Nitric oxide modulates TGF-β–directive signals to suppress Foxp3+ regulatory T cell differentiation and potentiate Th1 development
10.4049/jimmunol.1100485 · 2011 · External reference
Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway
10.4049/jimmunol.160.12.5729 · 1998 · External reference
Nitrosative stress-induced apoptosis through inhibition of NF-κB
10.1074/jbc.m201638200 · 2002 · External reference
p21ras as a common signaling target of reactive free radicals and cellular redox stress
10.1074/jbc.270.36.21195 · 1995 · External reference
Nitric oxide and cell viability in inflammatory cells: a role for NO in macrophage function and fate
10.1016/j.tox.2004.11.035 · 2005 · External reference
Epigenetic control of the foxp3 locus in regulatory T cells
10.1371/journal.pbio.0050038 · 2007 · External reference
Epigenetic regulation of Foxp3 expression in regulatory T cells by DNA methylation
10.4049/jimmunol.182.1.259 · 2009 · External reference
MicroRNAs and immunity: novel players in the regulation of normal immune function and inflammation
10.1016/j.semcancer.2008.01.005 · 2008 · External reference
Nitric oxide inhibits the transcription repressor Yin-Yang 1 binding activity at the silencer region of the Fas promoter: a pivotal role for nitric oxide in the up-regulation of Fas gene expression in human tumor cells
10.4049/jimmunol.167.1.75 · 2001 · External reference
Nitric oxide sensitizes tumor cells to TRAIL-induced apoptosis via inhibition of the DR5 transcription repressor Yin Yang 1
10.1016/j.niox.2008.08.001 · 2009 · External reference
Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide: an overview
10.1161/hh0102.102330 · 2002 · External reference
Irradiation promotes Akt-targeting therapeutic gene delivery to the tumor vasculature
10.1016/j.ijrobp.2006.11.031 · 2007 · External reference
Randomized phase II trial comparing nitroglycerin plus vinorelbine and cisplatin with vinorelbine and cisplatin alone in previously untreated stage IIIB/IV non–small-cell lung cancer
10.1200/jco.2005.04.0436 · 2006 · External reference
The role of nitric oxide in cancer
10.1038/sj.cr.7290133 · 2002 · External reference
Nitric oxide synthase inhibition enhances the antitumor effect of radiation in the treatment of squamous carcinoma xenografts
10.1371/journal.pone.0020147 · 2011 · External reference
How cancer metabolism is tuned for proliferation and vulnerable to disruption
10.1038/nature11706 · 2012 · External reference
Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study
10.1016/s1470-2045(07)70001-3 · 2007 · External reference
Dinitroazetidines are a novel class of anticancer agents and hypoxia-activated radiation sensitizers developed from highly energetic materials
10.1158/0008-5472.can-11-2303 · 2012 · External reference
NO or No NO, Increased Reduction of Nitrite to Nitric Oxide by Modified Red Blood Cells
2011 · External reference
Preclinical evaluation of the metabolism and disposition of RRx-001, a novel investigative anticancer agent
10.1124/dmd.112.046755 · 2012 · External reference
The multi-faceted behavior of nitric oxide in vascular “inflammation”: catchy terminology or true phenomenon?
10.1016/j.cardiores.2004.04.028 · 2004 · External reference
Nitric oxide: biphasic dose responses
10.1080/20014091111776 · 2001 · External reference
10.1593/tlo.11166 · 2011 · Admitted local publication
Real time dynamic imaging and current targeted therapies in the war on cancer: a new paradigm
10.7150/thno.5658 · 2013 · External reference