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References from Urokinase-Type Plasminogen Activator Deficiency Promotes Neoplasmatogenesis in the Colon of Mice. Local targets link to admitted publications; unresolved targets remain external evidence.
The microenvironment of the tumour-host interface
10.1038/35077241 · 2001 · External reference
Putting tumours in context
10.1038/35094059 · 2001 · External reference
Hallmarks of cancer: the next generation
10.1016/j.cell.2011.02.013 · 2011 · External reference
Inflammation and cancer: an ancient link with novel potentials
10.1002/ijc.23173 · 2007 · External reference
Emerging roles of proteases in tumour suppression
10.1038/nrc2228 · 2007 · External reference
Cancer-related inflammation
10.1038/nature07205 · 2008 · External reference
Immunity, inflammation, and cancer
10.1016/j.cell.2010.01.025 · 2010 · External reference
Proteolytic networks in cancer
10.1016/j.tcb.2010.12.002 · 2011 · External reference
Inflammation and colon cancer
10.1053/j.gastro.2010.01.058 · 2010 · External reference
Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing
10.1056/nejm198612253152606 · 1986 · External reference
Extracellular matrix moieties, cytokines, and enzymes: dynamic effects on immune cell behavior and inflammation
10.1002/jlb.67.2.149 · 2000 · External reference
Urokinase-type plasminogen activator
10.1016/j.biocel.2006.10.008 · 2007 · External reference
The urokinase receptor system, a key regulator at the intersection between inflammation, immunity, and coagulation
10.2174/138161211796718189 · 2011 · External reference
Development and disease in proteinase-deficient mice: role of the plasminogen, matrix metalloproteinase and coagulation system
10.1016/s0049-3848(98)00122-4 · 1998 · External reference
Evolving role of uPA/uPAR system in human cancers
10.1016/j.ctrv.2007.10.005 · 2008 · External reference
The role of plasminogen-plasmin system in cancer
10.1007/978-0-387-79962-9_4 · 2009 · External reference
Urokinase plasminogen activator system as a potential target for cancer therapy
10.2217/fon.09.108 · 2009 · External reference
The urokinase plasminogen activator system: role in malignancy
10.2174/1381612043453559 · 2004 · External reference
Tumor development is retarded in mice lacking the gene for urokinase-type plasminogen activator or its inhibitor, plasminogen activator inhibitor-1
2000 · External reference
Reduced metastasis of transgenic mammary cancer in urokinase-deficient mice
10.1002/ijc.20631 · 2005 · External reference
Reduced metastasis of polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice
10.1038/sj.onc.1201869 · 1998 · External reference
A urokinase-type plasminogen activator deficiency diminishes the frequency of intestinal adenomas in ApcMin/+ mice
10.1002/path.2236 · 2007 · External reference
Induction of primary cutaneous melanocytic neoplasms in urokinase-type plasminogen activator (uPA)-deficient and wild-type mice: cellular blue nevi invade but do not progress to malignant melanoma in uPA-deficient animals
1996 · External reference
CFTR suppresses tumor progression through miR-193b targeting urokinase plasminogen activator (uPA) in prostate cancer
10.1038/onc.2012.251 · 2013 · External reference
Urokinase-type plasminogen activator is a marker of aggressive phenotype and an independent prognostic factor in mismatch repair-proficient colorectal cancer
10.1016/j.humpath.2009.05.013 · 2010 · External reference
Clinical significance of the plasminogen activator system in relation to grade of tumor and treatment response in colorectal carcinoma patients
10.4149/neo_2011_05_377 · 2011 · External reference
Mechanism of activation of latent recombinant transforming growth factor β1 by plasmin
10.1083/jcb.110.4.1361 · 1990 · External reference
Latent TGF-β binding proteins: extracellular matrix association and roles in TGF-β activation
10.1080/10408360490460933 · 2004 · External reference
TGFβ signalling: a complex web in cancer progression
10.1038/nrc2853 · 2010 · External reference
Tumour microenvironment: TGFβ: the molecular Jekyll and Hyde of cancer
10.1038/nrc1926 · 2006 · External reference
Dextran sulfate sodium-induced colitis-associated neoplasia: a promising model for the development of chemopreventive interventions
10.1111/j.1745-7254.2007.00695.x · 2007 · External reference
Primary gastric choriocarcinoma in a dog
10.1016/j.jcpa.2008.06.003 · 2008 · External reference
CD4+ CD25+ regulatory T lymphocytes inhibit microbially induced colon cancer in Rag2-deficient mice
10.1016/s0002-9440(10)63863-1 · 2003 · External reference
Proinflammatory CD4+ CD45RBhi lymphocytes promote mammary and intestinal carcinogenesis in Apcmin/+ mice
10.1158/0008-5472.can-05-3445 · 2006 · External reference
A new mathematical model for relative quantification in real-time RT-PCR
10.1093/nar/29.9.e45 · 2001 · External reference
Plasmin/plasminogen system in colorectal cancer
10.1007/s00268-002-4050-8 · 2002 · External reference
In vitro and in vivo induction of antiangiogenic activity by plasminogen activators and captopril
10.1093/jnci/95.5.388 · 2003 · External reference
Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model
10.1093/jnci/djj208 · 2006 · External reference
Activation of urokinase plasminogen activator and its receptor axis is essential for macrophage infiltration in a prostate cancer mouse model
10.1593/neo.10728 · 2011 · External reference
ApcMin: a mouse model for intestinal and mammary tumorigenesis
10.1016/0959-8049(95)00181-h · 1995 · External reference
Strain differences in the susceptibility to azoxymethane and dextran sodium sulfate-induced colon carcinogenesis in mice
10.1093/carcin/bgi205 · 2006 · External reference
Colitis-accelerated colorectal cancer and metabolic dysregulation in a mouse model
10.1093/carcin/bgt135 · 2013 · External reference
Acute colitis induced by dextran sulfate sodium progresses to chronicity in C57BL/6 but not in BALB/c mice: correlation between symptoms and inflammation
10.1152/ajpgi.00467.2004 · 2005 · External reference
Dysplasia and cancer in the dextran sulfate sodium mouse colitis model. relevance to colitis-associated neoplasia in the human: a study of histopathology, B-catenin and p53 expression and the role of inflammation
10.1093/carcin/21.4.757 · 2000 · External reference
Pathology of mouse models of intestinal cancer: consensus report and recommendations
10.1053/gast.2003.50094 · 2003 · External reference
Unresolved reference
2003 · External reference
Dysplasia and carcinoma development in a repeated dextran sulfate sodium-induced colitis model
10.1046/j.1440-1746.2002.02853.x · 2002 · External reference
Tumour budding, uPA and PAI-1 are associated with aggressive behaviour in colon cancer
10.1002/jso.21611 · 2010 · External reference
CD4+ lymphocytes modulate prostate cancer progression in mice
10.1002/ijc.24452 · 2009 · External reference
CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice
10.1158/0008-5472.can-04-3104 · 2005 · External reference
Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice
10.1158/0008-5472.can-06-0558 · 2006 · External reference
Unifying roles for regulatory T cells and inflammation in cancer
10.1002/ijc.24923 · 2010 · External reference
Roles for inflammation and regulatory T cells in colon cancer
10.1177/0192623309354110 · 2010 · External reference
Linking tumor-associated macrophages, inflammation, and intestinal tumorigenesis: role of MCP-1
10.1152/ajpgi.00252.2012 · 2012 · External reference
A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
10.1111/j.1349-7006.2003.tb01386.x · 2003 · External reference
Crucial involvement of tumor-associated neutrophils in the regulation of chronic colitis-associated carcinogenesis in mice
10.1371/journal.pone.0051848 · 2012 · External reference
Innate immune signaling by toll-like receptor-4 (TLR4) shapes the inflammatory microenvironment in colitis-associated tumors
10.1002/ibd.20880 · 2009 · External reference
The inflammatory microenvironment in colorectal neoplasia
10.1371/journal.pone.0015366 · 2011 · External reference
The essential role of the in situ immune reaction in human colorectal cancer
10.1189/jlb.1107773 · 2008 · External reference
The wolf in sheep's clothing: the role of interleukin-6 in immunity, inflammation and cancer
10.1016/j.molmed.2007.12.007 · 2008 · External reference
Urokinase-type plasminogen activator in inflammatory cell recruitment and host defense against pneumocystis carinii in mice
10.1128/iai.67.2.879-884.1999 · 1999 · External reference
Urokinase-deficient mice fail to generate a type 2 immune response following schistosomal antigen challenge
10.1128/iai.72.1.461-467.2004 · 2004 · External reference
Receptor-independent role of the urokinase-type plasminogen activator during arteriogenesis
10.1096/fj.02-0800fje · 2003 · External reference
Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma
10.1093/carcin/bgm180 · 2007 · External reference
Transcriptional regulation of the urokinase receptor (u-PAR)—a central molecule of invasion and metastasis
10.1515/bc.2003.084 · 2003 · External reference
Regulatory T cells, tumour immunity and immunotherapy
10.1038/nri1806 · 2006 · External reference
What are regulatory T cells (treg) regulating in cancer and why?
10.1016/j.semcancer.2012.03.004 · 2012 · External reference
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
10.1038/nm1093 · 2004 · External reference
Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer
10.1007/s00262-008-0583-5 · 2009 · External reference
Prognostic significance of regulatory T cells in tumor
10.1002/ijc.25464 · 2010 · External reference
Tumor-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer
10.1200/jco.2008.18.7229 · 2009 · External reference
Revisiting the prognostic value of regulatory T cells in patients with cancer
10.1200/jco.2009.23.0680 · 2009 · External reference
Regulatory T cells and tumour immunity—observations in mice and men
10.1111/j.1365-2567.2007.02748.x · 2008 · External reference
Cancer inflammation and regulatory T cells
10.1002/ijc.25430 · 2010 · External reference
PLAU inferred from a correlation network is critical for suppressor function of regulatory T cells
10.1038/msb.2012.56 · 2012 · External reference
Neutralisation of uPA with a monoclonal antibody reduces plasmin formation and delays skin wound healing in tPA-deficient mice
10.1371/journal.pone.0012746 · 2010 · External reference
Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice
10.1038/sj.emboj.7601173 · 2006 · External reference
Cell associated urokinase activity and colonic epithelial cells in health and disease
10.1136/gut.32.2.191 · 1991 · External reference
Plasminogen activators in the intestine of patients with inflammatory bowel disease
10.1055/s-0038-1647042 · 1988 · External reference
Effects of dietary folate and aging on gene expression in the colonic mucosa of rats: implications for carcinogenesis
10.1093/carcin/bgg150 · 2004 · External reference
Molecular profiling of a rat model of colitis: validation of known inflammatory genes and identification of novel disease-associated targets
10.1097/01.mib.0000231575.11678.8c · 2006 · External reference
Role of transforming growth factor beta in human cancer
10.1200/jco.2005.02.047 · 2005 · External reference
Pathobiology of transforming growth factor β in cancer, fibrosis and immunologic disease, and therapeutic considerations
10.1038/labinvest.3700669 · 2007 · External reference
