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References from Hippo Signaling Mediates Proliferation, Invasiveness, and Metastatic Potential of Clear Cell Renal Cell Carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Renal cell carcinoma
10.1016/s0140-6736(09)60229-4 · 2009 · External reference
Kidney cancer pathology in the new context of targeted therapy
10.1159/000315543 · 2011 · External reference
Elucidation of a universal size-control mechanism in Drosophila and mammals
10.1016/j.cell.2007.07.019 · 2007 · External reference
The emerging role of the hippo pathway in cell contact inhibition, organ size control, and cancer development in mammals
10.1016/j.ccr.2008.02.011 · 2008 · External reference
Expression of Yes-associated protein in common solid tumors
10.1016/j.humpath.2008.04.012 · 2008 · External reference
Yes-associated protein is an independent prognostic marker in hepatocellular carcinoma
10.1002/cncr.24495 · 2009 · External reference
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation
10.1101/gad.1824509 · 2009 · External reference
Reduced membrane major histocompatibility complex class I density and stability in a subset of human renal cell carcinomas with low TAP and LMP expression
1996 · External reference
Establishment and characterization of colon carcinoma and renal cell carcinoma primary cultures
2000 · External reference
Characterization of primary renal carcinoma cultures
10.1159/000107956 · 2007 · External reference
Genus- and species-specific identification of mycoplasmas by 16S rRNA amplification
10.1128/aem.58.8.2606-2615.1992 · 1992 · External reference
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancers
10.1158/0008-5472.can-06-3281 · 2007 · External reference
A cost effective non-commercial ECL-solution for Western blot detections yielding strong signals and low background
10.1016/j.jim.2006.07.027 · 2007 · External reference
A novel signaling pathway impact analysis
10.1093/bioinformatics/btn577 · 2009 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2−ΔΔCT Method
10.1006/meth.2001.1262 · 2001 · External reference
Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models
10.4161/cbt.12.7.16475 · 2011 · External reference
Cancer genome landscapes
10.1126/science.1235122 · 2013 · External reference
The predictive capacity of personal genome sequencing
10.1126/scitranslmed.3003380 · 2012 · External reference
Downregulation of SAV1 plays a role in pathogenesis of high-grade clear cell renal cell carcinoma
10.1186/1471-2407-11-523 · 2011 · External reference
High-resolution analysis of DNA copy number alterations and gene expression in renal clear cell carcinoma
10.1002/path.2239 · 2007 · External reference
Multilevel whole-genome analysis reveals candidate biomarkers in clear cell renal cell carcinoma
10.1158/0008-5472.can-12-0656 · 2012 · External reference
Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma
10.1038/ng.1014 · 2012 · External reference
Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes
10.1038/nature08672 · 2010 · External reference
Aberrant epithelial morphology and persistent epidermal growth factor receptor signaling in a mouse model of renal carcinoma
10.1073/pnas.0902031106 · 2009 · External reference
NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway
10.1083/jcb.201009069 · 2011 · External reference
The ciliopathy disease protein NPHP9 promotes nuclear delivery and activation of the oncogenic transcriptional regulator TAZ
10.1093/hmg/dds408 · 2012 · External reference
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain
10.1073/pnas.1212021109 · 2012 · External reference
NOV (nephroblastoma overexpressed) and the CCN family of genes: structural and functional issues
10.1136/mp.54.2.57 · 2001 · External reference
Cyr61/CCN1 and CTGF/CCN2 mediate the proangiogenic activity of VHL-mutant renal carcinoma cells
10.1093/carcin/bgn019 · 2008 · External reference
Cyr61/CCN1 affects the integrin-mediated migration of prostate cancer cells (PC-3) in vitro
10.5414/cpp51047 · 2013 · External reference
The expression of thrombospondin-1 and p53 in clear cell renal cell carcinoma: its relationship to angiogenesis, cell proliferation and cancer specific survival
10.1016/j.juro.2009.07.015 · 2009 · External reference
Clinical trials with endothelin receptor antagonists: what went wrong and where can we improve?
10.1016/j.lfs.2012.07.034 · 2012 · External reference
Endothelin-1 promotes cell survival in renal cell carcinoma through the ETA receptor
10.1016/j.canlet.2006.02.007 · 2007 · External reference
Endothelin axis expression is markedly different in the two main subtypes of renal cell carcinoma
10.1002/cncr.20222 · 2004 · External reference
Targeting the endothelin axis with atrasentan, in combination with IFN-alpha, in metastatic renal cell carcinoma
10.1038/bjc.2011.515 · 2012 · External reference
Endothelin-2, the forgotten isoform: emerging role in the cardiovascular system, ovarian development, immunology and cancer
10.1111/j.1476-5381.2011.01786.x · 2013 · External reference
Specific expression of human endothelin-2 (ET-2) gene in a renal adenocarcinoma cell line. Molecular cloning of cDNA encoding the precursor of ET-2 and its characterization
10.1016/0014-5793(90)81348-r · 1990 · External reference
Expression of endothelin 2 and localized clear cell renal cell carcinoma
10.1016/j.humpath.2011.07.011 · 2012 · External reference
A role for endothelin-2 and its receptors in breast tumor cell invasion
10.1158/0008-5472.can-03-1069 · 2004 · External reference
Expression of endothelins and their receptors promotes an invasive phenotype of breast tumor cells but is insufficient to induce invasion in benign cells
10.1089/dna.2005.24.766 · 2005 · External reference
Tumor endothelin-1 enhances metastatic colonization of the lung in mouse xenograft models of bladder cancer
10.1172/jci42912 · 2011 · External reference
MYC pathway is activated in clear cell renal cell carcinoma and essential for proliferation of clear cell renal cell carcinoma cells
10.1016/j.canlet.2008.07.038 · 2009 · External reference
Differential expression of full-length telomerase reverse transcriptase mRNA and telomerase activity between normal and malignant renal tissues
10.1158/1078-0432.ccr-05-0099 · 2005 · External reference
Investigation of c-myc and K-ras amplification in renal clear cell adenocarcinoma
10.1016/s0304-3835(96)04527-2 · 1997 · External reference
The endothelin axis: emerging role in cancer
10.1038/nrc990 · 2003 · External reference
Endothelin—biology and disease
10.1016/j.cellsig.2010.05.002 · 2010 · External reference
Complex cadherin expression in renal cell carcinoma
1996 · External reference
E-cadherin expression in renal cell cancer and its significance in metastasis and survival
10.1038/bjc.1995.76 · 1995 · External reference
The level of cadherin-6 mRNA in peripheral blood is associated with the site of metastasis and with the subsequent occurrence of metastases in renal cell carcinoma
10.1002/cncr.20479 · 2004 · External reference
Cadherin-6 gene expression in conventional renal cell carcinoma: a useful marker to detect circulating tumor cells
2005 · External reference
Comprehensive molecular characterization of clear cell renal cell carcinoma
10.1038/nature12222 · 2013 · External reference
microRNA-21 governs TORC1 activation in renal cancer cell proliferation and invasion
10.1371/journal.pone.0037366 · 2012 · External reference
