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References from Cancer-associated fibroblasts-derived CAV1 promotes epithelial-mesenchymal transition and stemness in bladder cancer through activation of the LIF/STAT3 signaling pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
European association of urology guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2025 guidelines
10.1016/j.eururo.2025.02.019 · 2025 · External reference
Global burden and cross-country inequalities in urinary tumors from 1990 to 2021 and predicted incidence changes to 2046
2025 · External reference
Advances in diagnosis and treatment of bladder cancer
10.1136/bmj-2023-076743 · 2024 · External reference
Precision medicine in bladder cancer: redefining treatment paradigms through ADCs, immunotherapy, and molecular subtyping
10.1016/j.critrevonc.2026.105348 · 2026 · External reference
Molecular biomarkers of progression in non-muscle-invasive bladder cancer - beyond conventional risk stratification
10.1038/s41585-024-00914-7 · 2025 · External reference
The implications of single-cell RNA-seq analysis in prostate cancer: unraveling tumor heterogeneity, therapeutic implications and pathways towards personalized therapy
2024 · External reference
New roles of tumor-derived exosomes in tumor microenvironment
10.21147/j.issn.1000-9604.2024.02.05 · 2024 · External reference
Cancer-associated fibroblasts promote lymphatic metastasis in cholangiocarcinoma via the PDGF-BB/PDGFR-β mediated paracrine signaling network
10.14336/ad.2023.0420 · 2024 · External reference
Transforming cancer cells for long-term living with cancer: an inspiring new approach
10.21147/j.issn.1000-9604.2023.02.03 · 2023 · External reference
Metabolic control of immunity and inflammation: mitochondrial dynamics, pharmacological targets, and therapeutic opportunities
10.1016/j.phrs.2026.108194 · 2026 · External reference
The role of the tumor microenvironment in mediating radiopharmaceutical therapy: bridging nuclear medicine and cancer immunotherapy
2026 · External reference
Bioengineer mesenchymal stem cell for treatment of glioma by IL-12 mediated microenvironment reprogramming and nCD47-SLAMF7 mediated phagocytosis regulation of macrophages
2024 · External reference
Application of single-cell RNA sequencing in head and neck squamous cell carcinoma
10.21147/j.issn.1000-9604.2023.04.01 · 2023 · External reference
Programmed cell death network in cancer drug resistance: a framework for therapeutic intervention
10.1016/j.drup.2026.101387 · 2026 · External reference
The complex interplay of tumor-infiltrating cells in driving therapeutic resistance pathways
10.1186/s12964-024-01776-7 · 2024 · External reference
POSTN secretion by extracellular matrix cancer-associated fibroblasts (eCAFs) correlates with poor ICB response via macrophage chemotaxis activation of Akt signaling pathway in gastric cancer
10.14336/ad.2023.0503 · 2023 · External reference
Interferon-dependent SLC14A1(+) cancer-associated fibroblasts promote cancer stemness via WNT5A in bladder cancer
10.1016/j.ccell.2022.11.005 · 2022 · External reference
Single-cell RNA sequencing highlights the role of inflammatory cancer-associated fibroblasts in bladder urothelial carcinoma
10.1038/s41467-020-18916-5 · 2020 · External reference
CAV1 unveils a novel therapeutic target for nephrolithiasis by modulating CaSR and ER stress
10.1016/j.bbadis.2025.167751 · 2025 · External reference
Molecular mechanisms of glaucoma pathogenesis with implications to caveolin adaptor protein and caveolin-Shp2 axis
10.14336/ad.2023.1012 · 2024 · External reference
Curcumin-loaded nanoemulsions and phloroglucinol target hexokinase 2 to inhibit caveolin-1-induced glycolysis and metastasis in cancer cells
10.1016/j.biopha.2025.118339 · 2025 · External reference
Identification and validation of senescence-related signature by combining single cell and bulk transcriptome data analysis to predict the prognosis and identify the key gene CAV1 in pancreatic cancer
10.2147/jir.s489985 · 2024 · External reference
A reference profile-free deconvolution method to infer cancer cell-intrinsic subtypes and tumor-type-specific stromal profiles
10.1186/s13073-020-0720-0 · 2020 · External reference
TISCH: a comprehensive web resource enabling interactive single-cell transcriptome visualization of tumor microenvironment
10.1093/nar/gkaa1020 · 2021 · External reference
FerrDb V2: update of the manually curated database of ferroptosis regulators and ferroptosis-disease associations
10.1093/nar/gkac935 · 2023 · External reference
The molecular signatures database (MSigDB) hallmark gene set collection
2015 · External reference
BEST: a web application for comprehensive biomarker exploration on large-scale data in solid tumors
10.1186/s40537-023-00844-y · 2023 · External reference
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression
10.1186/s13046-023-02860-5 · 2023 · External reference
Melanoma cells with diverse invasive potential differentially induce the activation of normal human fibroblasts
10.1186/s12964-022-00871-x · 2022 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
10.1006/meth.2001.1262 · 2001 · External reference
circFARP1 enables cancer-associated fibroblasts to promote gemcitabine resistance in pancreatic cancer via the LIF/STAT3 axis
10.1186/s12943-022-01501-3 · 2022 · External reference
Scientific advancements in drug development and trials for urothelial carcinoma: insights from the 2023 ASCO-GU cancers symposium
10.14336/ad.2023.0502 · 2023 · External reference
Relationship between clonal evolution and drug resistance in bladder cancer: a genomic research review
10.1016/j.phrs.2024.107302 · 2024 · External reference
Characterization of cancer-related fibroblasts in bladder cancer and construction of CAFs-based bladder cancer classification: insights from single-cell and multi-omics analysis
2025 · External reference
Characterization of the stem cell landscape and identification of a stemness-associated prognostic signature in bladder cancer
10.1186/s12935-024-03465-4 · 2024 · External reference
FOS-driven inflammatory CAFs promote colorectal cancer liver metastasis via the SFRP1-FGFR2-HIF1 axis
10.7150/thno.111625 · 2025 · External reference
Tumor exosomal RNPEP promotes lung metastasis of liver cancer via inducing cancer-associated fibroblast activation
10.1111/cas.16417 · 2025 · External reference
Mitochondrial function meets oncology: the multifaceted role of TFAM across cancer types
10.1007/s10495-026-02305-2 · 2026 · External reference
An overview: the diversified role of mitochondria in cancer metabolism
10.7150/ijbs.81609 · 2023 · External reference
Intratumoral microorganisms in tumors: current understanding and emerging therapeutic strategies
2020 · External reference
Microbiota and urinary tumor immunity: mechanisms, therapeutic implications, and future perspectives
10.21147/j.issn.1000-9604.2024.06.03 · 2024 · External reference
Breast cancer-derived CAV1 promotes lung metastasis by regulating integrin α6β4 and the recruitment and polarization of tumor-associated neutrophils
10.7150/ijbs.94153 · 2024 · External reference
Cancer-associated fibroblast senescence and its relation with tumour-infiltrating lymphocytes and PD-L1 expressions in intrahepatic cholangiocarcinoma
2022 · External reference
Endothelial caveolin and its scaffolding domain in cancer
10.1007/s10555-020-09895-6 · 2020 · External reference
Caveolin-1: an ambiguous entity in breast cancer
10.1186/s12943-025-02297-8 · 2025 · External reference
CTHRC1 derived from cancer-associated fibroblasts promotes pancreatic cancer progression and metastasis via the LIF-STAT3 pathway
10.1002/cam4.71126 · 2025 · External reference
Super-enhancer driven LIF/LIFR-STAT3-SOX2 regulatory feedback loop promotes cancer stemness in head and neck squamous cell carcinoma
2024 · External reference
Pharmacological inhibition of the LIF/LIFR autocrine loop reveals vulnerability of ovarian cancer cells to ferroptosis
2024 · External reference
The pleiotropic role, functions and targeted therapies of LIF/LIFR axis in cancer: old spectacles with new insights
10.1016/j.bbcan.2022.188737 · 2022 · External reference