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References from A mucosal prime–systemic boost strategy using a glycoengineered bacterial membrane vesicle vaccine elicits protective mucosal immunity against pneumococci in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis
10.1128/iai.00517-06 · 2006 · External reference
Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis
10.4049/jimmunol.173.10.6357 · 2004 · External reference
Nasal-subcutaneous prime-boost regimen for inactivated whole-virus influenza vaccine efficiently protects mice against both upper and lower respiratory tract infections
10.1016/j.bbrc.2021.03.099 · 2021 · External reference
Mucosal immunity to poliovirus
10.1038/s41385-021-00428-0 · 2022 · External reference
Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial
10.1016/s0140-6736(14)60934-x · 2014 · External reference
Antibody responses and protection stimulated by sequential oral-parenteral immunization of mice with rotavirus
10.1016/s0264-410x(98)00244-8 · 1999 · External reference
Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants
10.1038/s41586-021-04117-7 · 2021 · External reference
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose
10.1126/science.abh1282 · 2021 · External reference
mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection
10.1126/science.abg9175 · 2021 · External reference
A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles
10.1038/s41541-022-00572-z · 2022 · External reference
Glycine significantly enhances bacterial membrane vesicle production: a powerful approach for isolation of LPS-reduced membrane vesicles of probiotic Escherichia coli
10.1111/1751-7915.13572 · 2020 · External reference
Intranasal vaccination with probiotic Escherichia coli membrane vesicles displaying pneumococcal capsular polysaccharides elicits mucosal immunity
10.1038/s41541-025-01345-0 · 2025 · External reference
Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the global burden of disease study 2019
10.1016/s0140-6736(22)02185-7 · 2022 · External reference
Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the global burden of disease study 2016
10.1016/s1473-3099(18)30310-4 · 2018 · External reference
Mucosal adjuvanticity and mucosal booster effect of colibactin-depleted probiotic Escherichia coli membrane vesicles
10.1080/21645515.2024.2337987 · 2024 · External reference
Assessment of periodontitis vaccine using three different bacterial outer membrane vesicles in canine model
10.1128/msphere.01033-24 · 2025 · External reference
Harnessing mucosal immunity for protective vaccines
10.1038/s41577-026-01273-7 · 2026 · External reference
An engineered nano-vesicle adjuvant platform (ENAP) for cytokine delivery enables a novel antigen-coordinated vaccine against helicobacter pylori
10.1002/jev2.70274 · 2026 · External reference
A bivalent outer membrane vesicle-based intranasal vaccine to prevent infection of periodontopathic bacteria
10.1016/j.vaccine.2023.05.058 · 2023 · External reference
Über die Grundlagen einer neuen ursächlichen Bekämpfung der pathologischen Darmflora
10.1055/s-0028-1135392 · 1916 · External reference
Glycoengineered outer membrane vesicles: a novel platform for bacterial vaccines
10.1038/srep24931 · 2016 · External reference
Association of serotypes of Streptococcus pneumoniae with age in invasive pneumococcal disease
10.1128/jcm.01937-09 · 2010 · External reference
Glycine induction method: effective production of immunoactive bacterial membrane vesicles with low endotoxin content
10.1007/978-1-0716-1900-1_13 · 2022 · External reference
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
2020 · External reference
Establishment of an animal model using recombinant NOD.B10.D2 mice to study initial adhesion of oral streptococci
2004 · External reference
Effect of three types of mixed anesthetic agents alternate to ketamine in mice
10.1538/expanim.60.481 · 2011 · External reference
Development and validation of a fourfold multiplexed opsonization assay (MOPA4) for pneumococcal antibodies
10.1128/cvi.00112-06 · 2006 · External reference
Unresolved reference
External reference
An engineered nano-vesicle adjuvant platform (ENAP) for cytokine delivery enables a novel antigen-coordinated vaccine against helicobacter pylori
10.1002/jev2.70274 · ExternalCitation · doi-reference
Glycine induction method: effective production of immunoactive bacterial membrane vesicles with low endotoxin content
10.1007/978-1-0716-1900-1_13 · ExternalCitation · doi-reference
Nasal-subcutaneous prime-boost regimen for inactivated whole-virus influenza vaccine efficiently protects mice against both upper and lower respiratory tract infections
10.1016/j.bbrc.2021.03.099 · ExternalCitation · doi-reference
A bivalent outer membrane vesicle-based intranasal vaccine to prevent infection of periodontopathic bacteria
10.1016/j.vaccine.2023.05.058 · ExternalCitation · doi-reference
Effect of a single inactivated poliovirus vaccine dose on intestinal immunity against poliovirus in children previously given oral vaccine: an open-label, randomised controlled trial
10.1016/s0140-6736(14)60934-x · ExternalCitation · doi-reference
Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the global burden of disease study 2019
10.1016/s0140-6736(22)02185-7 · ExternalCitation · doi-reference
Antibody responses and protection stimulated by sequential oral-parenteral immunization of mice with rotavirus
10.1016/s0264-410x(98)00244-8 · ExternalCitation · doi-reference
Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990-2016: a systematic analysis for the global burden of disease study 2016
10.1016/s1473-3099(18)30310-4 · ExternalCitation · doi-reference
Mucosal immunity to poliovirus
10.1038/s41385-021-00428-0 · ExternalCitation · doi-reference
A highly immunogenic vaccine platform against encapsulated pathogens using chimeric probiotic Escherichia coli membrane vesicles
10.1038/s41541-022-00572-z · ExternalCitation · doi-reference
Intranasal vaccination with probiotic Escherichia coli membrane vesicles displaying pneumococcal capsular polysaccharides elicits mucosal immunity
10.1038/s41541-025-01345-0 · ExternalCitation · doi-reference
Harnessing mucosal immunity for protective vaccines
10.1038/s41577-026-01273-7 · ExternalCitation · doi-reference
Hybrid immunity improves B cells and antibodies against SARS-CoV-2 variants
10.1038/s41586-021-04117-7 · ExternalCitation · doi-reference
Glycoengineered outer membrane vesicles: a novel platform for bacterial vaccines
10.1038/srep24931 · ExternalCitation · doi-reference
Über die Grundlagen einer neuen ursächlichen Bekämpfung der pathologischen Darmflora
10.1055/s-0028-1135392 · ExternalCitation · doi-reference
Mucosal adjuvanticity and mucosal booster effect of colibactin-depleted probiotic Escherichia coli membrane vesicles
10.1080/21645515.2024.2337987 · ExternalCitation · doi-reference
Glycine significantly enhances bacterial membrane vesicle production: a powerful approach for isolation of LPS-reduced membrane vesicles of probiotic Escherichia coli
10.1111/1751-7915.13572 · ExternalCitation · doi-reference
mRNA vaccination boosts cross-variant neutralizing antibodies elicited by SARS-CoV-2 infection
10.1126/science.abg9175 · ExternalCitation · doi-reference
Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose
10.1126/science.abh1282 · ExternalCitation · doi-reference
Development and validation of a fourfold multiplexed opsonization assay (MOPA4) for pneumococcal antibodies
10.1128/cvi.00112-06 · ExternalCitation · doi-reference
Intranasal boosting with an adenovirus-vectored vaccine markedly enhances protection by parenteral Mycobacterium bovis BCG immunization against pulmonary tuberculosis
10.1128/iai.00517-06 · ExternalCitation · doi-reference
Association of serotypes of Streptococcus pneumoniae with age in invasive pneumococcal disease
10.1128/jcm.01937-09 · ExternalCitation · doi-reference
Assessment of periodontitis vaccine using three different bacterial outer membrane vesicles in canine model
10.1128/msphere.01033-24 · ExternalCitation · doi-reference
Effect of three types of mixed anesthetic agents alternate to ketamine in mice
10.1538/expanim.60.481 · ExternalCitation · doi-reference
Single mucosal, but not parenteral, immunization with recombinant adenoviral-based vaccine provides potent protection from pulmonary tuberculosis
10.4049/jimmunol.173.10.6357 · ExternalCitation · doi-reference