Research graph
References from An integrated immunoinformatics and experimental pipeline identifies an LCL-scaffolded OmpA loop 3 construct as a protective vaccine candidate against Acinetobacter baumannii. Local targets link to admitted publications; unresolved targets remain external evidence.
Deciphering the virulence factors, regulation, and immune response to Acinetobacter baumannii infection
10.3389/fcimb.2023.1053968 · 2023 · External reference
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10.1016/s1473-3099(17)30753-3 · 2018 · External reference
Old drugs, new lifelines: an update on drug repurposing against multidrug-resistant Acinetobacter baumannii
10.1016/j.jiph.2026.103264 · 2026 · External reference
In silico design of an immunogen against Acinetobacter baumannii based on a novel model for native structure of outer membrane protein a
10.1016/j.micpath.2017.02.028 · 2017 · External reference
Acinetobacter baumannii OmpA is a selective antibiotic permeant porin
10.1021/acsinfecdis.7b00168 · 2017 · External reference
Outer membrane protein a (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection
10.1186/s12929-020-0617-7 · 2020 · External reference
Specific egg yolk immunoglobulin as a promising non-antibiotic biotherapeutic product against Acinetobacter baumannii pneumonia infection
10.1038/s41598-021-81356-8 · 2021 · External reference
Specific egg yolk antibodies (IgY) confer protection against Acinetobacter baumannii in a murine pneumonia model
10.1111/jam.14135 · 2019 · External reference
Acinetobacter baumannii rOmpA vaccine dose alters immune polarization and immunodominant epitopes
10.1016/j.vaccine.2012.11.008 · 2013 · External reference
Active and passive immunization protects against lethal, extreme drug resistant-Acinetobacter baumannii infection
10.1371/journal.pone.0029446 · 2012 · External reference
A two-protein cocktail elicits a protective immune response against Acinetobacter baumannii in a murine infection model
10.1016/j.micpath.2023.106262 · 2023 · External reference
Combination of BauA and OmpA elicit immunoprotection against Acinetobacter baumannii in a murine sepsis model
10.1016/j.micpath.2022.105874 · 2022 · External reference
Mucosal immunization with purified OmpA elicited protective immunity against infections caused by multidrug-resistant Acinetobacter baumannii
10.1016/j.micpath.2016.04.019 · 2016 · External reference
Outer membrane vesicles containing OmpA induce mitochondrial fragmentation to promote pathogenesis of Acinetobacter baumannii
10.1038/s41598-020-79966-9 · 2021 · External reference
OmpA virulence factor, a promising conserved vaccine candidate against Acinetobacter baumannii, could trigger autoreactive immune responses in susceptible population
10.1186/s12865-025-00766-9 · 2025 · External reference
Design and evaluation of a multi-epitope assembly peptide vaccine against Acinetobacter baumannii infection in mice
10.4414/smw.2019.20052 · 2019 · External reference
Hybrid antigens expressing surface loops of BauA from Acinetobacter baumannii are capable of inducing protection against infection
10.3389/fimmu.2022.933445 · 2022 · External reference
Designing a novel peptide-based multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Providencia heimbachae
2022 · External reference
Immunoinformatics approach to design multi-epitope-based vaccine against Machupo virus taking viral nucleocapsid as a potential candidate
2022 · External reference
A reverse vaccinology approach to design an mRNA-based vaccine to provoke a robust immune response against HIV-1
2025 · External reference
Immunopharmacologsical and structural insights into Rift Valley fever virus envelope glycoproteins: an immunoinformatics approach to multi-epitope vaccine design
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Immunopharmacological design of a multi-epitope vaccine targeting sarbecovirus spike glycoprotein
10.1007/s00210-026-05534-z · 2026 · External reference
Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii
10.1038/s41598-025-88191-1 · 2025 · External reference
In silico design of a novel hybrid epitope-based antigen harboring highly exposed immunogenic peptides of BamA, OmpA, and Omp34 against Acinetobacter baumannii
10.1016/j.intimp.2024.113066 · 2024 · External reference
A unique antigen against SARS-CoV-2, Acinetobacter baumannii, and Pseudomonas aeruginosa
10.1038/s41598-022-14877-5 · 2022 · External reference
OmpA is the principal nonspecific slow porin of Acinetobacter baumannii
10.1128/jb.00435-12 · 2012 · External reference
The OmpA family of proteins: roles in bacterial pathogenesis and immunity
10.1016/j.vetmic.2012.08.019 · 2013 · External reference
Unresolved reference
2016 · External reference
Utility of hybrid transferrin binding protein antigens for protection against pathogenic Neisseria species
10.3389/fimmu.2019.00247 · 2019 · External reference
Design and production of hybrid antigens for targeting integral outer membrane proteins in gram-negative bacteria
2021 · External reference
Hybrid antigens expressing surface loops of ZnuD from Acinetobacter baumannii is capable of inducing protection against infection
10.3389/fimmu.2020.00158 · 2020 · External reference
Improved method for predicting linear B-cell epitopes
10.1186/1745-7580-2-2 · 2006 · External reference
BepiPred-2.0: improving sequence-based B-cell epitope prediction using conformational epitopes
10.1093/nar/gkx346 · 2017 · External reference
Improved method for linear B-cell epitope prediction using antigen’s primary sequence
10.1371/journal.pone.0062216 · 2013 · External reference
Prediction of continuous B‐cell epitopes in an antigen using recurrent neural network
10.1002/prot.21078 · 2006 · External reference
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10.1186/1471-2105-8-4 · 2007 · External reference
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10.1007/s00894-014-2278-5 · 2014 · External reference
In silico approach for predicting toxicity of peptides and proteins
10.1371/journal.pone.0073957 · 2013 · External reference
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10.1093/bioinformatics/btp386 · 2009 · External reference
Protein identification and analysis tools on the ExPASy server
2005 · External reference
Prediction of linear B-cell epitopes using amino acid pair antigenicity scale
10.1007/s00726-006-0485-9 · 2007 · External reference
Porter 5: state-of-the-art ab initio prediction of protein secondary structure in 3 and 8 classes
2018 · External reference
The s2D method: simultaneous sequence-based prediction of the statistical populations of ordered and disordered regions in proteins
10.1016/j.jmb.2014.12.007 · 2015 · External reference
The influence of gapped positions in multiple sequence alignments on secondary structure prediction methods
10.1016/j.compbiolchem.2004.09.005 · 2004 · External reference
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10.1093/nar/gkv332 · 2015 · External reference
The I-TASSER suite: protein structure and function prediction
10.1038/nmeth.3213 · 2015 · External reference
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10.1093/nar/gky427 · 2018 · External reference
LOMETS3: integrating deep learning and profile alignment for advanced protein template recognition and function annotation
10.1093/nar/gkac248 · 2022 · External reference
The trRosetta server for fast and accurate protein structure prediction
10.1038/s41596-021-00628-9 · 2021 · External reference
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10.1107/s0021889892009944 · 1993 · External reference
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10.1002/pro.5560020916 · 1993 · External reference
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10.1093/nar/gkm290 · 2007 · External reference
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2014 · External reference
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10.1021/ct700301q · 2008 · External reference
ElliPro: a new structure-based tool for the prediction of antibody epitopes
10.1186/1471-2105-9-514 · 2008 · External reference
The ClusPro web server for protein–protein docking
10.1038/nprot.2016.169 · 2017 · External reference
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10.1002/pro.3289 · 2018 · External reference
PEP-FOLD4: a pH-dependent force field for peptide structure prediction in aqueous solution
10.1093/nar/gkad376 · 2023 · External reference
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10.1038/s41596-020-0312-x · 2020 · External reference
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10.1093/protein/8.2.127 · 1995 · External reference
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10.1371/journal.pone.0009862 · 2010 · External reference
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10.2144/000114017 · 2013 · External reference
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10.1016/0003-2697(76)90527-3 · 1976 · External reference
Mouse models of Acinetobacter baumannii infection
2017 · External reference
Toxoplasma gondii elongation factor 1-alpha (TgEF-1α) is a novel vaccine candidate antigen against toxoplasmosis
2017 · External reference
Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology
10.1016/j.ijantimicag.2015.03.001 · 2015 · External reference
Therapeutic options for Acinetobacter baumannii infections: an update
10.1517/14656566.2012.729820 · 2012 · External reference
Epitope-based vaccine as a universal vaccination strategy against toxoplasma gondii infection: a mini-review
10.5455/javar.2019.f329 · 2019 · External reference
Vaccinomics to design a multi-epitopes vaccine for Acinetobacter baumannii
10.3390/ijerph19095568 · 2022 · External reference
Subunit vaccines for Acinetobacter baumannii
10.3389/fimmu.2022.1088130 · 2023 · External reference
BauA and Omp34 surface loops trigger protective antibodies against Acinetobacter baumannii in a murine sepsis model
10.1016/j.intimp.2022.108731 · 2022 · External reference
Immunogenicity of loop 3 of Omp34 from a. Baumannii in loopless C-lobe of TbpB of N. Meningitidis
10.1016/j.intimp.2022.109013 · 2022 · External reference
In silico design and evaluation of Acinetobacter baumannii outer membrane protein a (OmpA) antigenic peptides as vaccine candidate in immunized mice
2019 · External reference
In silico screening of epitopes as potential vaccine candidates against pathogenic Acinetobacter baumannii
10.1007/s13258-025-01656-5 · 2025 · External reference
Structural variations within the transferrin binding site on transferrin-binding protein B, TbpB
10.1074/jbc.m110.206102 · 2011 · External reference
Proof of principle for epitope-focused vaccine design
10.1038/nature12966 · 2014 · External reference
Elicitation of structure-specific antibodies by epitope scaffolds
10.1073/pnas.1004728107 · 2010 · External reference
A new candidate epitope-based vaccine against PspA PhtD of Streptococcus pneumoniae: a computational experimental approach
10.3389/fcimb.2023.1271143 · 2023 · External reference
Design, development, and assessment of a novel multi-peptide vaccine targeting PspC, PsaA, and PhtD proteins of Streptococcus pneumoniae
10.1016/j.ijbiomac.2023.128924 · 2024 · External reference
In silico designing of a novel epitope-based candidate vaccine against Streptococcus pneumoniae with introduction of a new domain of PepO as adjuvant
10.1186/s12967-022-03590-6 · 2022 · External reference
Immunoinformatics-aided design of a new multi-epitope vaccine adjuvanted with domain 4 of pneumolysin against Streptococcus pneumoniae strains
10.1186/s12859-023-05175-6 · 2023 · External reference
Toll-like receptors and their crosstalk with other innate receptors in infection and immunity
10.1016/j.immuni.2011.05.006 · 2011 · External reference
Role of T-helper cells (CD4+ T cells) in human immune system against some microbial infection: a mini review
10.29328/journal.ijcmbt.1001012 · 2020 · External reference
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10.1086/317537 · 2001 · External reference
Bioinformatics analysis and consistency verification of a novel tuberculosis vaccine candidate HP13138PB
2023 · External reference
Development and evaluation of a multi-epitope subunit vaccine against group B Streptococcus infection
10.1080/22221751.2022.2122585 · 2022 · External reference
