Research graph
References from Engineered invasive Lactococcus lactis as an oral vaccine delivery platform is associated with compartmentalized immune modulation and enhances control of Leishmania infantum infection. Local targets link to admitted publications; unresolved targets remain external evidence.
Advances in Leishmania vaccines: current development and future prospects
10.3390/pathogens13090812 · 2024 · External reference
IL-12 and IFN-γ in response to Leishmania infantum antigens in felines from an endemic area for visceral leishmaniasis
2025 · External reference
Mucosal vaccines: wisdom from now and then
10.1093/intimm/dxab056 · 2021 · External reference
Mucosal vaccines: the promise and the challenge
10.1038/nri1777 · 2006 · External reference
Next generation mucosal vaccine strategy for respiratory pathogens
10.3390/vaccines11101585 · 2023 · External reference
Mucosal immunity and vaccination strategies: current insights and future perspectives
10.1186/s43556-025-00301-7 · 2025 · External reference
Effect of treatment with Lactococcus lactis NZ9000 on intestinal microbiota and mucosal immune responses against Clostridium perfringens in broiler chickens
10.3389/fmicb.2023.1257819 · 2023 · External reference
Lactococcus lactis as an effective mucosal vaccination carrier: a systematic literature review
2024 · External reference
Immunostimulation signaling via toll-like receptor 2 activation: a molecular mechanism of Lactococcus lactis OTG1204 in vitro and in vivo
2022 · External reference
Recombinant invasive Lactococcus lactis can transfer DNA vaccines either directly to dendritic cells or across an epithelial cell monolayer
10.1016/j.vaccine.2015.07.077 · 2015 · External reference
Recombinant invasive Lactococcus lactis carrying a DNA vaccine coding the Ag85A antigen increases IFN-γ, IL-6, and TNF-α cytokines after intranasal immunization
10.3389/fmicb.2017.01263 · 2017 · External reference
10.1371/journal.pntd.0003439
10.1371/journal.pntd.0003439 · External reference
Rectal administration of leishmania cells elicits a specific, Th1-associated IgG2a response in mice: new perspectives for mucosal vaccination against leishmaniasis after the repurposing of a study on an antiviral vaccine candidate
10.3390/tropicalmed8080406 · 2023 · External reference
Development of chimeric protein as a multivalent vaccine for human kinetoplastid infections: Chagas disease and leishmaniasis
10.1016/j.vaccine.2023.07.020 · 2023 · External reference
Unresolved reference
External reference
Reassessing the role of Staphylococcus aureus clumping factor and fibronectin-binding protein by expression in Lactococcus lactis
10.1128/iai.69.10.6296-6302.2001 · 2001 · External reference
ASCVac-1, a multi-peptide chimeric vaccine, protects mice against Ascaris suum infection
10.3389/fimmu.2021.788185 · 2021 · External reference
Multiple exposures to Ascaris suum induce tissue injury and mixed Th2/Th17 immune response in mice
10.1371/journal.pntd.0004382 · 2016 · External reference
NOD1 signaling regulates early tissue inflammation during helminth infection
2024 · External reference
Analysis of relative gene expression data using realtime quantitative PCR and the 2(-Delta Delta C(T)) Method
10.1006/meth.2001.1262 · 2001 · External reference
Alveolar macrophages and monocyte subpopulations during Plasmodium berghei NK65 experimental malaria-associated acute respiratory distress syndrome
10.1016/j.heliyon.2024.e33739 · 2024 · External reference
PCR-RFLP to identify Leishmania (Viannia) braziliensis and L. (leishmania) amazonensis causing American cutaneous leishmaniasis
10.1016/j.actatropica.2003.10.008 · 2004 · External reference
Detection and characterization of Leishmania (leishmania) and Leishmania (Viannia) by SYBR green-based real-time PCR and high-resolution melt analysis targeting kinetoplast minicircle DNA
10.1371/journal.pone.0088845 · 2014 · External reference
Welcome to the tidyverse
10.21105/joss.01686 · 2019 · External reference
Humoral immunity in leishmaniasis– prevention or promotion of parasite growth?
10.1016/j.cytox.2020.100046 · 2020 · External reference
Anti-leishmania IgG is a marker of disseminated leishmaniasis caused by Leishmania braziliensis
10.1016/j.ijid.2021.02.016 · 2021 · External reference
A role for IgG immune complexes during infection with the intracellular pathogen Leishmania
10.1084/jem.20041470 · 2005 · External reference
Gut immune cells and intestinal niche imprinting
10.1016/j.semcdb.2023.01.006 · 2023 · External reference
Mucosal immunity and trained innate immunity of the gut
10.3390/gastroent15030048 · 2024 · External reference
Intestinal antigen-presenting cells in mucosal immune homeostasis: crosstalk between dendritic cells, macrophages and B-cells
10.3748/wjg.v20.i29.9653 · 2014 · External reference
The role of intestinal macrophages in gastrointestinal homeostasis: heterogeneity and implications in disease
10.1016/j.jcmgh.2021.08.021 · 2021 · External reference
Kupffer cell and recruited macrophage heterogeneity orchestrate granuloma maturation and hepatic immunity in visceral leishmaniasis
10.1038/s41467-025-58360-x · 2025 · External reference
Immunogenicity, safety, and protective efficacy of mucosal vaccines against respiratory infectious diseases: a systematic review and meta-analysis
10.3390/vaccines13080825 · 2025 · External reference
Secretory IgA’s complex roles in immunity and mucosal homeostasis in the gut
10.1038/mi.2011.41 · 2011 · External reference
Leishmaniasis: complexity at the host–pathogen interface
10.1038/nrmicro2608 · 2011 · External reference
The immunology of susceptibility and resistance to Leishmania major in mice
10.1038/nri933 · 2002 · External reference
IL-17 and Th17 cells
10.1146/annurev.immunol.021908.132710 · 2009 · External reference
IL-17 and IL-22 are associated with protection against human kala azar caused by Leishmania donovani
2009 · External reference
The dichotomous nature of T helper 17 cells
10.1038/nri.2017.50 · 2017 · External reference
Th17 cells transdifferentiate into regulatory T cells during resolution of inflammation
10.1038/nature14452 · 2015 · External reference
Nasal administration of Lactococcus lactis improves local and systemic immune responses against Streptococcus pneumoniae
10.1111/j.1348-0421.2008.00050.x · 2008 · External reference
Early mucosal events promote distinct mucosal and systemic antibody responses to live attenuated influenza vaccine
10.1038/s41467-023-43842-7 · 2023 · External reference
Induction of superior systemic and mucosal protective immunity to SARS-CoV-2 by nasal administration of a VSV–ΔG–spike vaccine
10.3390/vaccines12050491 · 2024 · External reference