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References from Phytochemical profile and proteomic landscape associated with antineoplastic activity of Zingiber cassumunar Roxb. Essential oil in canine melanoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Exploring the anticancer potential of Origanum majorana essential oil monoterpenes alone and in combination against non-small cell lung cancer
10.3390/nu15235010 · 2023 · External reference
Monoterpenes modulating autophagy: a review study
10.1111/bcpt.13282 · 2020 · External reference
Phytochemicals and cytotoxic studies of zingiber cassumunar Roxb
2017 · External reference
A review of the modern principles and applications of solid-phase extraction techniques in chromatographic analysis
10.1007/s44211-022-00190-8 · 2022 · External reference
Plant terpenoid biosynthetic network and its multiple layers of regulation
10.1016/j.plipres.2024.101287 · 2024 · External reference
Terpinen-4-ol, the main component of Melaleuca alternifolia (tea tree) oil inhibits the in vitro growth of human melanoma cells
10.1046/j.0022-202x.2004.22236.x · 2004 · External reference
Are severe adverse events commonly observed in dogs during cancer chemotherapy? A retrospective study on 155 dogs
10.1111/vco.12782 · 2022 · External reference
Melanosomal sequestration of cytotoxic drugs contributes to the intractability of malignant melanomas
10.1073/pnas.0600213103 · 2006 · External reference
An overview of the chemical compositions and biological activities of essential oils from selected zingiber species (Zingiberaceae)
2025 · External reference
The essential oils component p-cymene induces proton leak through fo-ATP synthase and uncoupling of mitochondrial respiration
10.2147/jep.s16387 · 2011 · External reference
Focal adhesion kinase plays a dual role in TRAIL resistance and metastatic outgrowth of malignant melanoma
10.1038/s41419-022-04502-8 · 2022 · External reference
Mitophagy: Mechanisms, pathophysiological roles, and analysis
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Regulation of cancer cell metabolism: Oncogenic MYC in the driver's seat
10.1038/s41392-020-00235-2 · 2020 · External reference
A novel polyhalogenated monoterpene induces cell cycle arrest and apoptosis in breast cancer cells
10.3390/md17080437 · 2019 · External reference
Mechanism of action of thymol on cell membranes investigated through Lipid Langmuir monolayers at the air-Water interface and Molecular simulation
10.1021/acs.langmuir.6b00600 · 2016 · External reference
Calreticulin and cancer
10.1038/s41422-020-0383-9 · 2021 · External reference
HSPB1 Is essential for inducing resistance to proteotoxic stress in beta-cells
10.3390/cells10092178 · 2021 · External reference
Risk of toxicity from topical 5-fluorouracil treatment in patients carrying DPYD variant alleles
10.1002/cpt.3131 · 2024 · External reference
Phytochemicals and bioactivities of zingiber cassumunar Roxb
10.3390/molecules26082377 · 2021 · External reference
Non-apoptotic cell death signaling pathways in melanoma
10.3390/ijms21082980 · 2020 · External reference
The comparative oncology of canine malignant melanoma in targeted therapy: A systematic review of In vitro experiments and animal model reports
10.3390/ijms251910387 · 2024 · External reference
Identification of HSP90B1 in pan-cancer hallmarks to aid development of a potential therapeutic target
10.1186/s12943-023-01920-w · 2024 · External reference
Establishment and characterization of four canine melanoma cell lines
10.1292/jvms.66.1437 · 2004 · External reference
Differential expression analysis of Escherichia coli proteins using a novel software for relative quantitation of LC-MS/MS data
10.1002/pmic.200500921 · 2006 · External reference
Recent advances in radiosensitivity determinants in melanoma
10.1097/cco.0000000000000818 · 2022 · External reference
Repellent, larvicidal and adulticidal activities of essential oil from Dai medicinal plant Zingiber cassumunar against Aedes albopictus
10.1016/j.pld.2020.11.008 · 2021 · External reference
Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates
10.1371/journal.pgen.1004987 · 2015 · External reference
Effect of terpenes on the enhancement of skin permeation of lipophilic drugs: a systematic review
2024 · External reference
Phytochemical and safety evaluations of volatile terpenoids from Zingiber Cassumunar Roxb. On mature carp peripheral blood mononuclear cells and embryonic zebrafish
10.3390/molecules25030613 · 2020 · External reference
Oregano phytocomplex induces programmed cell death in melanoma lines via mitochondria and DNA damage
10.3390/foods9101486 · 2020 · External reference
Deregulation of glucose transporter 1 and glycolytic gene expression by c-Myc
10.1074/jbc.c000023200 · 2000 · External reference
The effect of Terpinen-4-ol on Human corneal epithelium
10.1167/tvst.13.12.18 · 2024 · External reference
Probability-based protein identification by searching sequence databases using mass spectrometry data
10.1002/(sici)1522-2683(19991201)20:18<3551::aid-elps3551>3.0.co;2-2 · 1999 · External reference
H2AX: A key player in DNA damage response and a promising target for cancer therapy
10.1016/j.biopha.2024.116663 · 2024 · External reference
Chromatin remodeling at DNA double-strand breaks
10.1016/j.cell.2013.02.011 · 2013 · External reference
Canine melanomas as models for Human melanomas: Clinical, histological, and genetic comparison
10.3390/genes10070501 · 2019 · External reference
Essential oils from fruits of Zanthoxylum armatum exhibit antioxidant, anti-inflammatory, and anticancer properties by inhibiting p38-MAPK pathway
10.1016/j.rechem.2025.102618 · 2025 · External reference
Environmental factors regulate plant secondary metabolites
10.3390/plants12030447 · 2023 · External reference
Citronellol, an acyclic monoterpene induces mitochondrial-mediated apoptosis through activation of proapoptotic factors in MCF-7 and MDA-MB-231 Human mammary tumor cells
10.1080/01635581.2020.1800766 · 2021 · External reference
Effect of elicitation on terpinen-4-ol production and differential expression analysis of terpenes biosynthesis genes in Zingiber montanum
10.1016/j.scienta.2024.113849 · 2025 · External reference
Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics
10.1021/ac026117i · 2003 · External reference
Endoplasmic reticulum stress induces ligand-independent TNFR1-mediated necroptosis in L929 cells
10.1038/cddis.2014.548 · 2015 · External reference
Plants of the genus Zingiber as a source of bioactive phytochemicals: From tradition to pharmacy
10.3390/molecules22122145 · 2017 · External reference
Anticancer activity of monoterpenes: a systematic review
10.1007/s11033-021-06578-5 · 2021 · External reference
Challenging proteostasis: Role of the chaperone network to control aggregation-prone proteins in Human disease
10.1007/978-3-030-40204-4_4 · 2020 · External reference
Canine melanoma: a review of diagnostics and comparative mechanisms of disease and immunotolerance in the era of the immunotherapies
2022 · External reference
STITCH 5: augmenting protein-chemical interaction networks with tissue and affinity data
10.1093/nar/gkv1277 · 2016 · External reference
Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation
10.3390/molecules25225319 · 2020 · External reference
Evaluation of sample fractionation using micro-scale liquid-phase isoelectric focusing on mass spectrometric identification and quantitation of proteins in a SILAC experiment
10.1002/rcm.2898 · 2007 · External reference
Conifer essential oils modulate oxidative stress and erythrocyte stability in Human blood in vitro
10.33594/000000835 · 2025 · External reference
Natural terpenes: self-assembly and membrane partitioning
10.1016/j.bpc.2006.02.007 · 2006 · External reference
Multiple facets of histone variant H2AX: a DNA double-strand-break marker with several biological functions
10.1093/nar/gkv061 · 2015 · External reference
Chemical composition and antibacterial, antifungal, allelopathic and acetylcholinesterase inhibitory activities of cassumunar-ginger
10.1002/jsfa.8474 · 2018 · External reference
DRP1, fission and apoptosis
10.1038/s41420-025-02458-0 · 2025 · External reference
Synergistic targeted inhibition of MEK and dual PI3K/mTOR diminishes viability and inhibits tumor growth of canine melanoma underscoring its utility as a preclinical model for human mucosal melanoma
10.1111/pcmr.12512 · 2016 · External reference
Terpinen-4-ol induces apoptosis in Human nonsmall cell lung cancer In vitro and In vivo
2012 · External reference
Alpha-pinene regulates miR-221 and induces G(2)/M phase cell cycle arrest in human hepatocellular carcinoma cells
10.1042/bsr20180980 · 2018 · External reference
Metabolic differences in Zingiber officinale Roscoe by geographical origin determined via multiplatform metabolomics and method for simultaneous analysis of six phenolic compounds
10.1111/1750-3841.17456 · 2024 · External reference
Ripk3 promotes ER stress-induced necroptosis in cardiac IR injury: A mechanism involving calcium overload/XO/ROS/mPTP pathway
10.1016/j.redox.2018.02.019 · 2018 · External reference
Selected monocyclic monoterpenes and their derivatives as effective anticancer therapeutic agents
10.3390/ijms22094763 · 2021 · External reference