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References from Virus-specific enhancement of the expression of CTLA-4 in T cells from target organs during early and late stages of PRRSV-1 infection with strains of different virulence. Local targets link to admitted publications; unresolved targets remain external evidence.
Thymic depletion of lymphocytes is associated with the virulence of PRRSV-1 strains
10.1016/j.vetmic.2016.04.005 · 2016 · External reference
Expansion of the rank structure of the family Arteriviridae and renaming its taxa
2018 · External reference
Evaluation of suitable reference genes for gene expression studies in porcine alveolar macrophages in response to LPS and LTA
10.1186/1756-0500-5-107 · 2012 · External reference
Functional impairment of PRRSV-specific peripheral CD3+CD8high cells
10.1051/vetres/2009029 · 2009 · External reference
Characterisation of lung cell infiltration during the early stage of infection by porcine reproductive and respiratory syndrome virus type 1 strains of different virulence
10.1016/j.vetmic.2025.110747 · 2025 · External reference
Cytokine profiles and phenotype regulation of antigen presenting cells by genotype-I porcine reproductive and respiratory syndrome virus isolates
10.1186/1297-9716-42-9 · 2011 · External reference
Changes in lymphocyte subsets and cytokines during European porcine reproductive and respiratory syndrome: increased expression of IL-12 and IL-10 and proliferation of CD4(-)CD8(high)
10.1089/vim.2009.0003 · 2009 · External reference
ctive and respiratory syndrome virus isolates with that of the Lelystad virus
10.1177/030098589503200606 · 1995 · External reference
T cell exhaustion during persistent viral infections
10.1016/j.virol.2014.12.033 · 2015 · External reference
The role of immune checkpoint molecules in PRRSV-2-induced immune modulation: insights from comparative in vivo evaluation including NADC34-like PRRSV
10.1128/jvi.02298-24 · 2025 · External reference
First Identification and Genomic Characterization of NADC34-Like PRRSV Strains Isolated from MLV-Vaccinated Pigs in Korea
10.1155/2023/9995433 · 2023 · External reference
Immune checkpoint inhibitors in infectious disease
10.1111/imr.13388 · 2024 · External reference
Regulation of toll-like receptors 3, 7 and 9 in porcine alveolar macrophages by different genotype 1 strains of porcine reproductive and respiratory syndrome virus
10.1016/j.vetimm.2014.01.009 · 2014 · External reference
Single-cell transcriptomics of bronchoalveolar lavage during PRRSV infection with different virulence
10.1038/s41467-024-54676-2 · 2025 · External reference
Cell deconvolution-based integrated time-series network of whole blood transcriptome reveals systemic antiviral activities and cell-specific immunological changes against PRRSV infection
10.1186/s13567-025-01451-w · 2025 · External reference
Porcine reproductive and respiratory syndrome virus (PRRSV): pathogenesis and interaction with the immune system
10.1146/annurev-animal-022114-111025 · 2016 · External reference
Introduction of a PRRSV-1 strain of increased virulence in a pig production structure in Spain: virus evolution and impact on production
10.1186/s40813-022-00298-3 · 2023 · External reference
The challenge of PRRS immunology
10.1016/j.tvjl.2007.05.022 · 2008 · External reference
The role of CTLA-4 in the regulation of T cell immune responses
10.1046/j.1440-1711.1999.00795.x · 1999 · External reference
Increased pathogenicity of European porcine reproductive and respiratory syndrome virus is associated with enhanced adaptive responses and viral clearance
10.1016/j.vetmic.2012.11.024 · 2013 · External reference
Selection of reference genes for gene expression studies in pig tissues using SYBR green qPCR
10.1186/1471-2199-8-67 · 2007 · External reference
Impact of PRRSV strains of different in vivo virulence on the macrophage population of the thymus
10.1016/j.vetmic.2019.04.016 · 2019 · External reference
Beyond T-Cells: functional characterization of CTLA-4 expression in immune and non-immune cell types
10.3389/fimmu.2020.608024 · 2020 · External reference
Immunopathological features of highly pathogenic Korean Lineage B PRRSV-2: insights into virulence indicators and host immune responses
10.3389/fimmu.2025.1599468 · 2025 · External reference
PD-L1 expression is increased in monocyte derived dendritic cells in response to porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus infections
10.1016/j.vetimm.2015.09.013 · 2015 · External reference
10.1016/j.vetmic.2015.09.014
10.1016/j.vetmic.2015.09.014 · 2015 · External reference
Virulent Lena strain induced an earlier and stronger downregulation of CD163 in bronchoalveolar lavage cells
10.1016/j.vetmic.2019.06.011 · 2019 · External reference
Expression of T-bet, Eomesodermin and GATA-3 in porcine αβ T cells
10.1016/j.dci.2016.02.022 · 2016 · External reference
Up-regulation of immune checkpoints in the thymus of PRRSV-1-infected piglets in a virulence-dependent fashion
10.3389/fimmu.2021.671743 · 2021 · External reference
PRRSV-1 induced lung lesion is associated with an imbalance between costimulatory and coinhibitory immune checkpoints
10.3389/fmicb.2022.1007523 · 2023 · External reference
The scene of lung pathology during PRRSV-1 infection
10.3389/fvets.2024.1330990 · 2024 · External reference
Immunopathogenesis of lung lesions induced by the highly virulent Rosalía strain of PRRSV-1 circulating in Spain since 2020
10.1016/j.tvjl.2026.106647 · 2026 · External reference
Time series transcriptomic analysis of bronchoalveolar lavage cells from piglets infected with virulent or low-virulent porcine reproductive and respiratory syndrome virus 1
10.1128/jvi.01140-21 · 2022 · External reference
Primer3Plus, an enhanced web interface to Primer3
10.1093/nar/gkm306 · 2007 · External reference
Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulence
10.1016/j.vetmic.2012.09.013 · 2013 · External reference
Overexpression of programmed death ligands in naturally occurring postweaning multisystemic wasting syndrome
10.1089/vim.2014.0097 · 2015 · External reference
Up-regulated expression of PD-1 and its ligands during acute classical swine fever virus infection in swine
10.1016/j.rvsc.2014.07.023 · 2014 · External reference
TIM-3 and its regulatory role in immune responses
2010 · External reference
