Research graph
References from Airway infection with murine γ-herpesvirus 68 triggers gut-to-liver bacterial translocation via increased intestinal permeability. Local targets link to admitted publications; unresolved targets remain external evidence.
Systemic viral infections and collateral damage in the liver
10.2353/ajpath.2006.051296 · 2006 · External reference
The gut-liver axis in liver disease: pathophysiological basis for therapy
10.1016/j.jhep.2019.10.003 · 2020 · External reference
Interferon-alpha, -beta and -gamma induce CXCL9 and CXCL10 secretion by human thyrocytes: modulation by peroxisome proliferator-activated receptor-gamma agonists
10.1016/j.cyto.2010.01.009 · 2010 · External reference
Infectious mononucleosis
10.1038/cti.2015.1 · 2015 · External reference
Herpesvirus latency confers symbiotic protection from bacterial infection
10.1038/nature05762 · 2007 · External reference
Mechanisms and functions of intestinal vascular specialization
10.1084/jem.20222008 · 2024 · External reference
How EBV infects: the tropism and underlying molecular mechanism for viral infection
10.3390/v14112372 · 2022 · External reference
The significance of Interferon-γ–Triggered internalization of tight-junction proteins in inflammatory bowel disease
10.1126/stke.3162006pe1 · 2006 · External reference
Epstein-Barr virus: biology and clinical disease
10.1016/j.cell.2022.08.026 · 2022 · External reference
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
10.1371/journal.ppat.1001052 · 2010 · External reference
Differential γ-Herpesvirus distribution in distinct anatomical locations and cell subsets during persistent infection in mice
10.4049/jimmunol.170.7.3828 · 2003 · External reference
Epstein-Barr virus: current questions and challenges
10.1016/j.tvr.2021.200218 · 2021 · External reference
Animal models for gammaherpesvirus infections: recent development in the analysis of virus-induced pathogenesis
10.3390/pathogens9020116 · 2020 · External reference
Mucins in intestinal mucosal defense and inflammation: learning from clinical and experimental studies
10.3389/fimmu.2020.02054 · 2020 · External reference
TLR4 896A/G and TLR9 1174G/A polymorphisms are associated with the risk of infectious mononucleosis
10.1038/s41598-020-70129-4 · 2020 · External reference
Type I interferon signaling enhances CD8 + T cell effector function and differentiation during murine gammaherpesvirus 68 infection
10.1128/jvi.02360-14 · 2014 · External reference
Interferon gamma upregulates the cytokine receptors IFNGR1 and TNFRSF1A in HT-29-MTX E12 cells
10.1016/j.cyto.2022.155892 · 2022 · External reference
Involvement of TLR4 in acute hepatitis associated with airway infection of murine γ-Herpesvirus 68
10.4049/jimmunol.2200653 · 2023 · External reference
Murine γ-Herpesvirus 68 induces severe lung inflammation in IL-27-Deficient mice with liver dysfunction preventable by oral neomycin
10.4049/jimmunol.1700412 · 2018 · External reference
Effect of three types of mixed anesthetic agents alternate to ketamine in mice
10.1538/expanim.60.481 · 2011 · External reference
Severe hepatitis caused by Epstein-Barr virus without infection of hepatocytes
10.1053/hupa.2001.25597 · 2001 · External reference
Type I interferons in inflammatory bowel diseases: balancing barrier integrity, repair and inflammation in the intestinal epithelium
10.3389/fmed.2025.1713424 · 2025 · External reference
Association between toll-like receptor 9 signaling defect and developing post-infectious irritable bowel syndrome
10.3389/fimmu.2025.1672117 · 2025 · External reference
Case series and review of liver dysfunction in COVID-19 patients
10.1097/meg.0000000000001806 · 2020 · External reference
Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression
10.1152/ajpgi.00412.2004 · 2005 · External reference
Molecular basis of Epstein–Barr Virus latency establishment and lytic reactivation
10.3390/v13122344 · 2021 · External reference
Natural history of murine γ-herpesvirus infection
10.1098/rstb.2000.0779 · 2001 · External reference
The paradox of Epstein–Barr virus-associated hepatitis
10.1016/j.jhep.2006.03.002 · 2006 · External reference
Pathologic inflammation in malnutrition is driven by proinflammatory intestinal microbiota, large intestine barrier dysfunction, and translocation of bacterial lipopolysaccharide
10.3389/fimmu.2022.846155 · 2022 · External reference
The ARRIVE guidelines 2.0: updated guidelines for reporting animal research
2020 · External reference
The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection
10.3389/fcimb.2023.1146381 · 2023 · External reference
Unresolved reference
2023 · External reference
Epstein-Barr virus hepatitis: a review of clinicopathologic features and differential diagnosis
10.5858/arpa.2018-0208-ra · 2018 · External reference
Type I interferon signaling controls gammaherpesvirus latency in vivo
10.3390/pathogens11121554 · 2022 · External reference
T cell-extrinsic IL-1 signaling controls long-term gammaherpesvirus infection by suppressing viral reactivation
10.1016/j.virol.2022.09.006 · 2022 · External reference
The gut-liver axis and the intersection with the microbiome
10.1038/s41575-018-0011-z · 2018 · External reference
Virus-associated disruption of mucosal epithelial tight junctions and its role in viral transmission and spread
10.1080/21688370.2021.1943274 · 2021 · External reference
Mechanism of IFN-γ-induced endocytosis of tight junction proteins: Myosin II-dependent vacuolarization of the apical plasma membrane
10.1091/mbc.e05-03-0193 · 2005 · External reference
Pro-inflammatory cytokines as core mediators of colonic epithelial barrier dysfunction: roles of TNF-α, IFN-γ, IL-1β, and IL-6
10.3390/ijms27114722 · 2026 · External reference
Complete sequence and genomic analysis of murine gammaherpesvirus 68
10.1128/jvi.71.8.5894-5904.1997 · 1997 · External reference
Non‐hepatotropic viral hepatitis and its causative pathogens: the ongoing need for monitoring in children with severe acute hepatitis of unknown etiology
10.1002/ped4.12340 · 2022 · External reference
Gut–liver translocation of pathogen Klebsiella pneumoniae promotes hepatocellular carcinoma in mice
10.1038/s41564-024-01890-9 · 2025 · External reference
Conquering the host: determinants of pathogenesis learned from murine gammaherpesvirus 68
10.1146/annurev-virology-011921-082615 · 2021 · External reference
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells
10.1038/s41419-021-04151-3 · 2021 · External reference
Epstein–barr virus history and pathogenesis
10.3390/v15030714 · 2023 · External reference
Characteristics and clinical significance of gut microbiota in patients with epstein‐barr virus‐associated liver dysfunction
10.1111/1348-0421.13200 · 2025 · External reference
The chemokine superfamily revisited
10.1016/j.immuni.2012.05.008 · 2012 · External reference
Non‐hepatotropic viral hepatitis and its causative pathogens: the ongoing need for monitoring in children with severe acute hepatitis of unknown etiology
10.1002/ped4.12340 · ExternalCitation · doi-reference
Epstein-Barr virus: biology and clinical disease
10.1016/j.cell.2022.08.026 · ExternalCitation · doi-reference
Interferon-alpha, -beta and -gamma induce CXCL9 and CXCL10 secretion by human thyrocytes: modulation by peroxisome proliferator-activated receptor-gamma agonists
10.1016/j.cyto.2010.01.009 · ExternalCitation · doi-reference
Interferon gamma upregulates the cytokine receptors IFNGR1 and TNFRSF1A in HT-29-MTX E12 cells
10.1016/j.cyto.2022.155892 · ExternalCitation · doi-reference
The chemokine superfamily revisited
10.1016/j.immuni.2012.05.008 · ExternalCitation · doi-reference
The paradox of Epstein–Barr virus-associated hepatitis
10.1016/j.jhep.2006.03.002 · ExternalCitation · doi-reference
The gut-liver axis in liver disease: pathophysiological basis for therapy
10.1016/j.jhep.2019.10.003 · ExternalCitation · doi-reference
Epstein-Barr virus: current questions and challenges
10.1016/j.tvr.2021.200218 · ExternalCitation · doi-reference
T cell-extrinsic IL-1 signaling controls long-term gammaherpesvirus infection by suppressing viral reactivation
10.1016/j.virol.2022.09.006 · ExternalCitation · doi-reference
Infectious mononucleosis
10.1038/cti.2015.1 · ExternalCitation · doi-reference
Herpesvirus latency confers symbiotic protection from bacterial infection
10.1038/nature05762 · ExternalCitation · doi-reference
TNF-α synergises with IFN-γ to induce caspase-8-JAK1/2-STAT1-dependent death of intestinal epithelial cells
10.1038/s41419-021-04151-3 · ExternalCitation · doi-reference
Gut–liver translocation of pathogen Klebsiella pneumoniae promotes hepatocellular carcinoma in mice
10.1038/s41564-024-01890-9 · ExternalCitation · doi-reference
The gut-liver axis and the intersection with the microbiome
10.1038/s41575-018-0011-z · ExternalCitation · doi-reference
TLR4 896A/G and TLR9 1174G/A polymorphisms are associated with the risk of infectious mononucleosis
10.1038/s41598-020-70129-4 · ExternalCitation · doi-reference
Severe hepatitis caused by Epstein-Barr virus without infection of hepatocytes
10.1053/hupa.2001.25597 · ExternalCitation · doi-reference
Virus-associated disruption of mucosal epithelial tight junctions and its role in viral transmission and spread
10.1080/21688370.2021.1943274 · ExternalCitation · doi-reference
Mechanisms and functions of intestinal vascular specialization
10.1084/jem.20222008 · ExternalCitation · doi-reference
Mechanism of IFN-γ-induced endocytosis of tight junction proteins: Myosin II-dependent vacuolarization of the apical plasma membrane
10.1091/mbc.e05-03-0193 · ExternalCitation · doi-reference
Case series and review of liver dysfunction in COVID-19 patients
10.1097/meg.0000000000001806 · ExternalCitation · doi-reference
Natural history of murine γ-herpesvirus infection
10.1098/rstb.2000.0779 · ExternalCitation · doi-reference
Characteristics and clinical significance of gut microbiota in patients with epstein‐barr virus‐associated liver dysfunction
10.1111/1348-0421.13200 · ExternalCitation · doi-reference
The significance of Interferon-γ–Triggered internalization of tight-junction proteins in inflammatory bowel disease
10.1126/stke.3162006pe1 · ExternalCitation · doi-reference
Type I interferon signaling enhances CD8 + T cell effector function and differentiation during murine gammaherpesvirus 68 infection
10.1128/jvi.02360-14 · ExternalCitation · doi-reference
Complete sequence and genomic analysis of murine gammaherpesvirus 68
10.1128/jvi.71.8.5894-5904.1997 · ExternalCitation · doi-reference
Conquering the host: determinants of pathogenesis learned from murine gammaherpesvirus 68
10.1146/annurev-virology-011921-082615 · ExternalCitation · doi-reference
Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression
10.1152/ajpgi.00412.2004 · ExternalCitation · doi-reference
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections
10.1371/journal.ppat.1001052 · ExternalCitation · doi-reference
Effect of three types of mixed anesthetic agents alternate to ketamine in mice
10.1538/expanim.60.481 · ExternalCitation · doi-reference
Systemic viral infections and collateral damage in the liver
10.2353/ajpath.2006.051296 · ExternalCitation · doi-reference
The innate and T-cell mediated immune response during acute and chronic gammaherpesvirus infection
10.3389/fcimb.2023.1146381 · ExternalCitation · doi-reference
Mucins in intestinal mucosal defense and inflammation: learning from clinical and experimental studies
10.3389/fimmu.2020.02054 · ExternalCitation · doi-reference
Pathologic inflammation in malnutrition is driven by proinflammatory intestinal microbiota, large intestine barrier dysfunction, and translocation of bacterial lipopolysaccharide
10.3389/fimmu.2022.846155 · ExternalCitation · doi-reference
Association between toll-like receptor 9 signaling defect and developing post-infectious irritable bowel syndrome
10.3389/fimmu.2025.1672117 · ExternalCitation · doi-reference
Type I interferons in inflammatory bowel diseases: balancing barrier integrity, repair and inflammation in the intestinal epithelium
10.3389/fmed.2025.1713424 · ExternalCitation · doi-reference
Pro-inflammatory cytokines as core mediators of colonic epithelial barrier dysfunction: roles of TNF-α, IFN-γ, IL-1β, and IL-6
10.3390/ijms27114722 · ExternalCitation · doi-reference
Type I interferon signaling controls gammaherpesvirus latency in vivo
10.3390/pathogens11121554 · ExternalCitation · doi-reference
Animal models for gammaherpesvirus infections: recent development in the analysis of virus-induced pathogenesis
10.3390/pathogens9020116 · ExternalCitation · doi-reference
Molecular basis of Epstein–Barr Virus latency establishment and lytic reactivation
10.3390/v13122344 · ExternalCitation · doi-reference
How EBV infects: the tropism and underlying molecular mechanism for viral infection
10.3390/v14112372 · ExternalCitation · doi-reference
Epstein–barr virus history and pathogenesis
10.3390/v15030714 · ExternalCitation · doi-reference
Differential γ-Herpesvirus distribution in distinct anatomical locations and cell subsets during persistent infection in mice
10.4049/jimmunol.170.7.3828 · ExternalCitation · doi-reference
Murine γ-Herpesvirus 68 induces severe lung inflammation in IL-27-Deficient mice with liver dysfunction preventable by oral neomycin
10.4049/jimmunol.1700412 · ExternalCitation · doi-reference
Involvement of TLR4 in acute hepatitis associated with airway infection of murine γ-Herpesvirus 68
10.4049/jimmunol.2200653 · ExternalCitation · doi-reference
Epstein-Barr virus hepatitis: a review of clinicopathologic features and differential diagnosis
10.5858/arpa.2018-0208-ra · ExternalCitation · doi-reference
