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References from In vivo-edited CCR7+IL-7+ DCs reverse T cell exhaustion by promoting T memory stem cell differentiation. Local targets link to admitted publications; unresolved targets remain external evidence.
Advances in the development of personalized neoantigen-based therapeutic cancer vaccines
10.1038/s41571-020-00460-2 · 2021 · External reference
Combination therapy with oncolytic virus and T cells or mRNA vaccine amplifies antitumor effects
10.1038/s41392-024-01824-1 · 2024 · External reference
Delivery technologies for cancer immunotherapy
10.1038/s41573-018-0006-z · 2019 · External reference
Clinical implications of T cell exhaustion for cancer immunotherapy
10.1038/s41571-022-00689-z · 2022 · External reference
IL-2 regulates tumor-reactive CD8(+) T cell exhaustion by activating the aryl hydrocarbon receptor
10.1038/s41590-020-00850-9 · 2021 · External reference
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer
10.1146/annurev-immunol-041015-055318 · 2019 · External reference
CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions
10.1146/annurev-med-012017-043208 · 2018 · External reference
The future of immune checkpoint therapy
10.1126/science.aaa8172 · 2015 · External reference
T memory stem cells in health and disease
10.1038/nm.4241 · 2017 · External reference
The roles of stem cell memory T cells in hematological malignancies
10.1186/s13045-015-0214-5 · 2015 · External reference
Stem cell-like memory T cells: A perspective from the dark side
10.1016/j.cellimm.2020.104273 · 2021 · External reference
Akt inhibition at the initial stage of CAR-T preparation enhances the CAR-positive expression rate, memory phenotype and in vivo efficacy
2019 · External reference
A human memory T cell subset with stem cell-like properties
10.1038/nm.2446 · 2011 · External reference
Antigen-specific CD8+ memory stem T cells generated from human peripheral blood effectively eradicate allogeneic targets in mice
10.1186/s13287-018-1080-1 · 2018 · External reference
Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15
10.1182/blood-2014-01-552174 · 2014 · External reference
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors
10.1182/blood-2012-05-431718 · 2013 · External reference
Nonactivated and IL-7 cultured CD19-specific CAR T cells are enriched in stem cell phenotypes and functionally superior
10.1182/bloodadvances.2023010607 · 2024 · External reference
The evolutionary history of lymphoid organs
10.1038/ni1435 · 2007 · External reference
Temperature sensitive liposome based cancer nanomedicine enables tumour lymph node immune microenvironment remodelling
10.1038/s41467-023-38014-6 · 2023 · External reference
Development of a Cancer Vaccine Using In Vivo Click-Chemistry-Mediated Active Lymph Node Accumulation for Improved Immunotherapy
10.1002/adma.202006007 · 2021 · External reference
Lymph-Node-Targeted Cholesterolized TLR7 Agonist Liposomes Provoke a Safe and Durable Antitumor Response
10.1021/acs.nanolett.1c01968 · 2021 · External reference
Application of Nano-Delivery Systems in Lymph Nodes for Tumor Immunotherapy
10.1007/s40820-023-01125-2 · 2023 · External reference
Dendritic cells in cancer immunology
10.1038/s41423-021-00741-5 · 2022 · External reference
Dendritic cells in cancer immunology and immunotherapy
10.1038/s41577-019-0210-z · 2020 · External reference
Dendritic Cells and CCR7 Expression: An Important Factor for Autoimmune Diseases, Chronic Inflammation, and Cancer
10.3390/ijms22158340 · 2021 · External reference
Scavenging of soluble and immobilized CCL21 by ACKR4 regulates peripheral dendritic cell emigration
10.1073/pnas.2025763118 · 2021 · External reference
Dendritic cell migration in inflammation and immunity
10.1038/s41423-021-00726-4 · 2021 · External reference
Interstitial dendritic cell guidance by haptotactic chemokine gradients
10.1126/science.1228456 · 2013 · External reference
CCR7 and its ligands: balancing immunity and tolerance
10.1038/nri2297 · 2008 · External reference
Towards personalized, tumour-specific, therapeutic vaccines for cancer
10.1038/nri.2017.131 · 2018 · External reference
Therapeutic cancer vaccines: advancements, challenges, and prospects
10.1038/s41392-023-01674-3 · 2023 · External reference
Immunogenic cell stress and death
10.1038/s41590-022-01132-2 · 2022 · External reference
Consensus guidelines for the detection of immunogenic cell death
10.4161/21624011.2014.955691 · 2014 · External reference
Immunogenic Cell Death Activates the Tumor Immune Microenvironment to Boost the Immunotherapy Efficiency
2022 · External reference
Trial Watch: Chemotherapy with immunogenic cell death inducers
10.4161/onci.27878 · 2014 · External reference
Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy
10.1016/j.apsb.2021.02.001 · 2021 · External reference
Lipid nanoparticles produce chimeric antigen receptor T cells with interleukin-6 knockdown in vivo
10.1016/j.jconrel.2022.08.033 · 2022 · External reference
Intracavity generation of glioma stem cell-specific CAR macrophages primes locoregional immunity for postoperative glioblastoma therapy
10.1126/scitranslmed.abn1128 · 2022 · External reference
Advances in mRNA-LNP lung-targeted delivery strategies
10.20517/microstructures.2024.172 · 2025 · External reference
Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells
10.1038/s41587-022-01245-x · 2022 · External reference
