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References from Uremic Toxins and Mortality in Patients With Acute Kidney Injury Prior to and During Continuous Kidney Replacement Therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study
10.1007/s00134-015-3934-7 · 2015 · External reference
KDIGO clinical practice guideline for acute kidney injury
2012 · External reference
Prophylactic hemodialysis in the treatment of acute renal failure
10.7326/0003-4819-53-5-992 · 1960 · External reference
Have we reached the limit of mortality benefit with our approach to renal replacement therapy in acute kidney injury?
10.1053/j.ajkd.2013.09.004 · 2013 · External reference
A brief history of haemodialysis and continuous renal replacement therapy
10.1177/0310057x19853391 · 2019 · External reference
Intensity of renal support in critically ill patients with acute kidney injury
10.1056/nejmoa0802639 · 2008 · External reference
Intensity of continuous renal-replacement therapy in critically ill patients
10.1056/nejmoa0902413 · 2009 · External reference
Initiation strategies for renal-replacement therapy in the intensive care unit
10.1056/nejmoa1603017 · 2016 · External reference
Timing of renal-replacement therapy in patients with acute kidney injury and sepsis
10.1056/nejmoa1803213 · 2018 · External reference
Timing of initiation of renal-replacement therapy in acute kidney injury
10.1056/nejmoa2000741 · 2020 · External reference
Classification of uremic toxins and their role in kidney failure
10.2215/cjn.02660221 · 2021 · External reference
A history of uraemic toxicity and of the European Uraemic Toxin Work Group (EUTox)
2021 · External reference
Serum hippuric acid concentration in renal allograft rejection, ureter obstruction, and tubular necrosis
10.1111/j.1432-2277.1994.tb01272.x · 1994 · External reference
Low dialysance of asymmetric dimethylarginine (ADMA): in vivo and in vitro evidence of significant protein binding
10.5414/cnp62295 · 2004 · External reference
Serum metabolomic profiles from patients with acute kidney injury: a pilot study
10.1016/j.jchromb.2012.02.042 · 2012 · External reference
Two rapid, accurate liquid chromatography tandem mass spectrometry methods for the quantification of seven uremic toxins: an application for describing their accumulation kinetic profile in a context of acute kidney injury
10.1016/j.jchromb.2020.122234 · 2020 · External reference
Impaired tubular secretion of organic solutes in acute kidney injury
10.34067/kid.0001632020 · 2020 · External reference
In acute kidney injury, indoxyl sulfate impairs human endothelial progenitor cells: modulation by statin
10.1007/s10456-013-9339-8 · 2013 · External reference
Indoxyl sulfate enhances IL-1β-induced E-selectin expression in endothelial cells in acute kidney injury by the ROS/MAPKs/NFκB/AP-1 pathway
10.1007/s00204-015-1652-0 · 2016 · External reference
Serum indoxyl sulfate is associated with mortality in hospital-acquired acute kidney injury: a prospective cohort study
10.1186/s12882-019-1238-9 · 2019 · External reference
Evolution of protein-bound uremic toxins indoxyl sulphate and p-cresyl sulphate in acute kidney injury
10.1007/s11255-018-2056-x · 2019 · External reference
Acute kidney injury and organ dysfunction: what is the role of uremic toxins?
10.3390/toxins13080551 · 2021 · External reference
Highlighting levels of indoxyl sulphate among critically ill patients with acute nephrotoxicity; correlations between indoxyl sulphate levels and patients’ characteristics
2021 · External reference
VA/NIH Acute Renal Failure Trial Network. Model to predict mortality in critically ill adults with acute kidney injury
10.2215/cjn.02900311 · 2011 · External reference
In critically ill patients requiring CRRT, AKI is associated with increased respiratory failure and death versus ESRD
10.3109/0886022x.2011.615964 · 2011 · External reference
Clinical factors associated with initiation of renal replacement therapy in critically ill patients with acute kidney injury: a prospective multicenter observational study
10.1016/j.jcrc.2011.06.003 · 2012 · External reference
Hepcidin removal during continuous renal replacement therapy
10.1159/000534297 · 2024 · External reference
Cystatin C and kidney function recovery in patients requiring continuous KRT for acute kidney injury
10.2215/cjn.0000000000000531 · 2024 · External reference
A three-minute method for high-throughput quantitative metabolomics and quantitative tracing experiments of central carbon and nitrogen pathways
10.1002/rcm.7834 · 2017 · External reference
MetaboAnalyst 6.0: towards a unified platform for metabolomics data processing, analysis and interpretation
10.1093/nar/gkae253 · 2024 · External reference
Z scores, standard scores, and composite test scores explained
10.1177/02537176211046525 · 2021 · External reference
Implementing a class of permutation tests: the coin package
10.18637/jss.v028.i08 · 2008 · External reference
Tumor lysis syndrome and AKI: beyond crystal mechanisms
10.1681/asn.2021070997 · 2022 · External reference
Hyperuricemia is associated with acute kidney injury and all-cause mortality in hospitalized patients
10.1111/nep.13559 · 2019 · External reference
Preoperative serum uric acid predicts incident acute kidney injury following cardiac surgery
10.1186/s12882-018-0970-x · 2018 · External reference
Post-operative serum uric acid and acute kidney injury
10.5301/jn.5000173 · 2012 · External reference
Concentrations of representative uraemic toxins in a healthy versus non-dialysis chronic kidney disease paediatric population
10.1093/ndt/gfx224 · 2018 · External reference
Gut-derived uremic toxin handling in vivo requires OAT-mediated tubular secretion in chronic kidney disease
10.1172/jci.insight.133817 · 2020 · External reference
Metabolomic profiling of uremic solutes in CKD patients
10.1038/hr.2010.113 · 2010 · External reference
Effects of pyramid resistance-training system with different repetition zones on cardiovascular risk factors in older women: a randomized controlled trial
10.3390/ijerph17176115 · 2020 · External reference
Improvement of oxidative stress in older women is dependent on resistance training volume: Active Aging Longitudinal Study
10.1519/jsc.0000000000003602 · 2022 · External reference
Perioperative neurofilament light plasma concentrations and cognition before and after cardiac surgery: a prospective nested cohort study
10.1097/aln.0000000000004327 · 2022 · External reference
The associations between nutrition and circulating gut microbiota-derived uremic toxins in patients undergoing kidney replacement therapy: an observational, cross-sectional study
10.1016/j.clnesp.2024.11.022 · 2025 · External reference
Diet quality and protein-bound uraemic toxins: investigation of novel risk factors and the role of microbiome in chronic kidney disease
10.1053/j.jrn.2021.10.003 · 2022 · External reference
High-diversity plant-based diet and gut microbiome, plasma metabolome, and symptoms in adults with CKD
10.2215/cjn.0000000682 · 2025 · External reference
Dietary protein intake in CKD: quantity and quality
10.2215/cjn.0000000777 · 2026 · External reference
Broad-spectrum antibiotic use and poor outcomes in community-onset pneumonia: a cohort study
10.1183/13993003.00057-2019 · 2019 · External reference
Prevalence of antibiotic-resistant pathogens in culture-proven sepsis and outcomes associated with inadequate and broad-spectrum empiric antibiotic use
10.1001/jamanetworkopen.2020.2899 · 2020 · External reference
Antibiotic exposure aggravates Bacteroides-linked uremic toxicity in the gut-kidney axis
10.3389/fimmu.2022.737536 · 2022 · External reference
Current status and influencing factors of enteral nutrition interruption among critical patients: a systematic review
10.3389/fnut.2025.1462131 · 2025 · External reference
Enteral nutrition interruptions in critically ill patients: A prospective study on reasons, frequency and duration of interruptions of nutritional support during ICU stay
10.1016/j.clnesp.2022.10.019 · 2022 · External reference
Incidence, risk factors, and clinical consequence of enteral feeding intolerance in the mechanically ventilated critically ill: an analysis of a multicenter, multiyear database
10.1097/ccm.0000000000004712 · 2021 · External reference
A novel predictive model for hospital survival in critically ill patients with dialysis-dependent AKI: a retrospective single-center exploratory study
10.34067/kid.0007272021 · 2022 · External reference
Hyperlactatemia is a predictor of mortality in patients undergoing continuous renal replacement therapy for acute kidney injury
10.1186/s12882-023-03063-y · 2023 · External reference
Association of serum phosphate derangement with mortality in patients on continuous renal replacement therapy
10.1177/20543581221114697 · 2022 · External reference
Phosphate level predicts mortality in acute kidney injury patients undergoing continuous kidney replacement therapy and has a U-shaped association with mortality in patients with high disease severity: a multicenter retrospective study
10.23876/j.krcp.23.311 · 2024 · External reference