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References from An Optimized Treatment Protocol for Subretinal Injections Limits Intravitreal Vector Distribution. Local targets link to admitted publications; unresolved targets remain external evidence.
Ocular gene therapies in clinical practice: viral vectors and nonviral alternatives
10.1016/j.drudis.2019.05.038 · 2019 · External reference
Efficacy and safety of voretigene neparvovec (AAV2-hRPE65v2) in patients with RPE65-mediated inherited retinal dystrophy: a randomised, controlled, open-label, phase 3 trial
10.1016/s0140-6736(17)31868-8 · 2017 · External reference
A deviant immune response to viral proteins and transgene product is generated on subretinal administration of adenovirus and adeno-associated virus
10.1006/mthe.2002.0525 · 2002 · External reference
AAV8 can induce innate and adaptive immune response in the primate eye
10.1016/j.ymthe.2017.08.018 · 2017 · External reference
Long-term effect of gene therapy on Leber’s congenital amaurosis
10.1056/nejmoa1414221 · 2015 · External reference
Two-year results after AAV2-mediated gene therapy for choroideremia: The Alberta Experience
10.1016/j.ajo.2018.06.011 · 2018 · External reference
Ocular inflammatory response to intravitreal injection of adeno-associated virus vector: relative contribution of genome and capsid
10.1089/hum.2019.144 · 2020 · External reference
Antibody neutralization poses a barrier to intravitreal adeno-associated viral vector gene delivery to non-human primates
10.1038/gt.2014.115 · 2015 · External reference
Intraocular route of AAV2 vector administration defines humoral immune response and therapeutic potential
2008 · External reference
Humoral immune response after intravitreal but not after subretinal AAV8 in primates and patients
10.1167/iovs.17-22494 · 2018 · External reference
Superior retinal gene transfer and biodistribution profile of subretinal versus intravitreal delivery of AAV8 in nonhuman primates
10.1167/iovs.17-22473 · 2017 · External reference
Technique of retinal gene therapy: delivery of viral vector into the subretinal space
10.1038/eye.2017.158 · 2017 · External reference
Intraoperative optical coherence tomographic findings in patients undergoing subretinal gene therapy surgery
10.1186/s40942-020-00216-1 · 2020 · External reference
Retinal AAV8-RS1 gene therapy for X-linked retinoschisis: initial findings from a phase I/IIa trial by intravitreal delivery
10.1016/j.ymthe.2018.05.025 · 2018 · External reference
Surgical technique for subretinal gene therapy in humans with inherited retinal degeneration
10.1097/iae.0000000000002609 · 2019 · External reference
