Research graph
References from Local Complement Inhibition for Geographic Atrophy in Age-Related Macular Degeneration: Prospects, Challenges, and Unanswered Questions. Local targets link to admitted publications; unresolved targets remain external evidence.
Progression of geographic atrophy in age-related macular degeneration: AREDS2 report number 16
10.1016/j.ophtha.2018.05.028 · 2018 · External reference
Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis
10.1016/s2214-109x(13)70145-1 · 2014 · External reference
Complement C3 inhibitor pegcetacoplan for geographic atrophy secondary to age-related macular degeneration: a randomized phase 2 trial
10.1016/j.ophtha.2019.07.011 · 2020 · External reference
C5 Inhibitor avacincaptad pegol for geographic atrophy due to age-related macular degeneration: a randomized pivotal phase 2/3 trial
10.1016/j.ophtha.2020.08.027 · 2021 · External reference
Characterizing new-onset exudation in the randomized phase 2 FILLY trial of complement inhibitor pegcetacoplan for geographic atrophy
10.1016/j.ophtha.2021.02.025 · 2021 · External reference
Characterisation of macular neovascularisation in geographic atrophy
10.1136/bjophthalmol-2020-316054 · 2021 · External reference
Targeting complement components C3 and C5 for the retina: key concepts and lingering questions
2020 · External reference
Re: Jaffe et al: C5 inhibitor avacincaptad pegol for geographic atrophy due to age-related macular degeneration: a randomized pivotal phase 2/3 trial (Ophthalmology. 2021;128:576–586)
10.1016/j.ophtha.2020.12.030 · 2021 · External reference
Square root transformation of geographic atrophy area measurements to eliminate dependence of growth rates on baseline lesion measurements: a reanalysis of Age-Related Eye Disease Study report no. 26
10.1001/jamaophthalmol.2013.572 · 2013 · External reference
A deep learning model for segmentation of geographic atrophy to study its long-term natural history
10.1016/j.ophtha.2020.02.009 · 2020 · External reference
Artificial intelligence algorithms for analysis of geographic atrophy: a review and evaluation
10.1167/tvst.9.2.57 · 2020 · External reference
Predicting geographic atrophy growth rate from fundus autofluorescence images using deep neural networks
2021 · External reference
Progression of photoreceptor degeneration in geographic atrophy secondary to age-related macular degeneration
10.1001/jamaophthalmol.2020.2914 · 2020 · External reference
