Research graph
References from Genome-Wide Association Study of Pterygium Versus Pinguecula Identifies Loci Associated with Lesion-Type Divergence. Local targets link to admitted publications; unresolved targets remain external evidence.
Ophthalmic pterygium: a stem cell disorder with premalignant features
10.1016/j.ajpath.2010.10.037 · 2011 · External reference
Unravelling the molecular tapestry of pterygium: insights into genes for diagnostic and therapeutic innovations
10.1038/s41433-024-03186-y · 2024 · External reference
Risk factors for pterygium: latest research progress on major pathogenesis
10.1016/j.exer.2024.109900 · 2024 · External reference
Transcriptome analysis of pterygium and pinguecula reveals evidence of genomic instability associated with chronic inflammation
10.3390/ijms222112090 · 2021 · External reference
Prevalence and risk factors of pterygium: a systematic review and meta-analysis
10.1016/j.survophthal.2018.03.001 · 2018 · External reference
Abnormal epithelial differentiation and tear film alteration in pinguecula
10.1167/iovs.08-2905 · 2009 · External reference
Pterygium and pinguecula: Electron microscopic study
10.1001/archopht.1967.00980030176010 · 1967 · External reference
Pinguecula and pterygium (a histopathological study)
1976 · External reference
Pterygium: an update on pathophysiology, clinical features, and management
2021 · External reference
Effect of pterygium surgery on corneal topography
10.1177/112067210801800203 · 2008 · External reference
Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy
10.1016/j.clae.2017.04.002 · 2017 · External reference
Long-term changes and effect of pterygium size on corneal topographic irregularity after recurrent pterygium surgery
10.1038/s41598-020-65376-4 · 2020 · External reference
Pathogenesis of pterygium
10.1038/eye.1989.31 · 1989 · External reference
Increased oxidative DNA damage, 8-hydroxydeoxy- guanosine, in human pterygium
10.1038/sj.eye.6702064 · 2006 · External reference
Histopathological variability and concomitant lesions in pterygium in a large case series
10.1155/2021/6623794 · 2021 · External reference
Pinguecula and actinic elastosis. An ultrastructural study
10.1111/j.1600-0560.1979.tb01162.x · 1979 · External reference
Pterygia pathogenesis: corneal invasion by matrix metalloproteinase expressing altered limbal epithelial basal cells
10.1001/archopht.119.5.695 · 2001 · External reference
Histology of pterygium: an electron microscopic study
10.1136/bjo.67.9.604 · 1983 · External reference
Angiogenesis in pterygium: study of microvessel density, vascular endothelial growth factor, and thrombospondin-1
10.1038/sj.eye.6702495 · 2007 · External reference
UVB-mediated induction of interleukin-6 and-8 in pterygia and cultured human pterygium epithelial cells
2002 · External reference
mTORC1 regulates apoptosis and cell proliferation in pterygium via targeting autophagy and FGFR3
10.1038/s41598-017-07844-y · 2017 · External reference
Overexpression of collagenase (MMP-1) and stromelysin (MMP-3) by pterygium head fibroblasts
2001 · External reference
Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data
10.1186/1755-8794-2-14 · 2009 · External reference
Immunohistochemical profile of VEGF, TGF-β and PGE2 in human pterygium and normal conjunctiva: experimental study and review of the literature
10.1177/039463201202500307 · 2012 · External reference
Investigation of oxidative stress in pterygium tissue
2011 · External reference
The role of the stromal extracellular matrix in the development of pterygium pathology: an update
10.3390/jcm10245930 · 2021 · External reference
Assessing genetic and environmental components for pterygium: a nationwide study in Taiwan
2024 · External reference
Relationships of heredity and dry eye with pterygia in black African patients
10.7196/samj.4416 · 2011 · External reference
Traditional eye medication and pterygium occurrence in Limpopo Province
10.7196/samj.5930 · 2012 · External reference
The NHGRI-EBI GWAS catalog: knowledgebase and deposition resource
10.1093/nar/gkac1010 · 2023 · External reference
Simple new approach to variable selection in regression, with application to genetic fine mapping
10.1111/rssb.12388 · 2020 · External reference
The genotype-tissue expression (GTEx) project
10.1038/ng.2653 · 2013 · External reference
Integration of eQTL and a single-cell Atlas in the human eye identifies causal genes for age-related macular degeneration
10.1016/j.celrep.2019.12.082 · 2020 · External reference
QTLbase2: an enhanced catalog of human quantitative trait loci on extensive molecular phenotypes
10.1093/nar/gkac1020 · 2022 · External reference
The mutational constraint spectrum quantified from variation in 141,456 humans
10.1038/s41586-020-2308-7 · 2020 · External reference
Differences and commonalities in the genetic architecture of protein quantitative trait loci in European and Arab populations
10.1093/hmg/ddac243 · 2023 · External reference
Common variation in a long non-coding RNA gene modulates variation of circulating TGF-β2 levels in metastatic colorectal cancer patients (Alliance)
10.1186/s12864-024-10354-7 · 2024 · External reference
Leveraging polygenic functional enrichment to improve GWAS power
10.1016/j.ajhg.2018.11.008 · 2019 · External reference
The interaction between signal regulatory protein alpha (SIRPα) and CD47: structure, function, and therapeutic target
10.1146/annurev-immunol-032713-120142 · 2014 · External reference
Cutting edge: signal-regulatory protein β1 is a DAP12-associated activating receptor expressed in myeloid cells
10.4049/jimmunol.164.1.9 · 2000 · External reference
Proteome profiling of clear cell renal cell carcinoma in von Hippel-Lindau patients highlights upregulation of Xaa-Pro aminopeptidase-1, an anti-proliferative and anti-migratory exoprotease
10.18632/oncotarget.21929 · 2017 · External reference
Adducins regulate remodeling of apical junctions in human epithelial cells
10.1091/mbc.e10-03-0259 · 2010 · External reference
RNA toxicity and missplicing in the common eye disease fuchs endothelial corneal dystrophy
10.1074/jbc.m114.621607 · 2015 · External reference
Cyclosporine A inhibits TGF-β2-induced myofibroblasts of primary cultured human pterygium fibroblasts
10.1016/j.bbrc.2016.12.002 · 2017 · External reference
Nintedanib regulates miR-23b-3p/TGFBR2 axis and competitively binds to TGFBR2 protein, inhibiting EMT process in human pterygium cells
10.18240/ijo.2025.05.03 · 2025 · External reference
Cross-ancestry genome-wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
10.1038/s41467-018-03646-6 · 2018 · External reference
Association of Myopia and genetic variants of TGFB2-AS1 and TGFBR1 in the TGF-β signaling pathway: a longitudinal study in Chinese school-aged children
2021 · External reference
Transcriptomics and network analysis highlight potential pathways in the pathogenesis of pterygium
10.1038/s41598-021-04248-x · 2022 · External reference
Novel mutations in COL6A3 that associated with Peters' Anomaly caused abnormal intracellular protein retention and decreased cellular resistance to oxidative stress
10.3389/fcell.2020.531986 · 2020 · External reference
