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References from Inflammatory Markers and Disease Progression in Moderate-Stage Retinitis Pigmentosa: Longitudinal Analysis from the Retinitis Pigmentosa Progression and Inflammatory Marker Registry Study. Local targets link to admitted publications; unresolved targets remain external evidence.
Retinitis pigmentosa
10.1016/s0140-6736(06)69740-7 · 2006 · External reference
Non-syndromic retinitis pigmentosa
10.1016/j.preteyeres.2018.03.005 · 2018 · External reference
Gene editing for CEP290-Associated retinal degeneration
10.1056/nejmoa2309915 · 2024 · External reference
Long-term effect of gene therapy on Leber's congenital amaurosis
10.1056/nejmoa1414221 · 2015 · External reference
Phase 1/2 AAV5-hRKp.RPGR (Botaretigene sparoparvovec) gene therapy: safety and efficacy in RPGR-Associated X-Linked retinitis pigmentosa
10.1016/j.ajo.2024.05.034 · 2024 · External reference
Subretinal gene therapy drug AGTC-501 for XLRP phase 1/2 multicenter Study (HORIZON): 24-Month safety and efficacy results
10.1016/j.ajo.2024.11.021 · 2025 · External reference
Gene editing technology: towards precision medicine in inherited retinal diseases
10.1080/08820538.2021.1887903 · 2021 · External reference
Advancing clinical trials for inherited retinal diseases: recommendations from the second Monaciano symposium
10.1167/tvst.9.7.2 · 2020 · External reference
Partial recovery of visual function in a blind patient after optogenetic therapy
10.1038/s41591-021-01351-4 · 2021 · External reference
Safety and stable survival of stem-cell-derived retinal organoid for 2 years in patients with retinitis pigmentosa
10.1016/j.stem.2023.11.004 · 2023 · External reference
Gene therapy for inherited retinal degenerations: initial successes and future challenges
10.1088/1741-2552/aa7a27 · 2017 · External reference
Assessment of visual function with cotoretigene toliparvovec in X-Linked retinitis pigmentosa in the randomized XIRIUS phase 2/3 Study
10.1016/j.ophtha.2024.02.023 · 2024 · External reference
A nationwide survey of newly certified visually impaired individuals in Japan for the fiscal year 2019: impact of the revision of criteria for visual impairment certification
10.1007/s10384-023-00986-9 · 2023 · External reference
Incidence and causes of visual impairment in Japan: the first nation-wide complete enumeration survey of newly certified visually impaired individuals
10.1007/s10384-018-0623-4 · 2019 · External reference
Innate immune response in retinal homeostasis and inflammatory disorders
10.1016/j.preteyeres.2019.100778 · 2020 · External reference
Neuroinflammation in retinitis pigmentosa: therapies targeting the innate immune system
2022 · External reference
Neuroinflammation as a therapeutic target in Retinitis Pigmentosa and Quercetin as its potential modulator
10.3390/pharmaceutics13111935 · 2021 · External reference
Necroptosis and neuroinflammation in retinal degeneration
10.3389/fnins.2022.911430 · 2022 · External reference
Multiple cytokine analyses of aqueous humor from the patients with retinitis pigmentosa
10.1016/j.cyto.2019.154943 · 2020 · External reference
Increased aqueous flare is associated with thickening of inner retinal layers in eyes with retinitis pigmentosa
10.1038/srep33921 · 2016 · External reference
Genetically predicted inflammatory cytokine levels and risk of retinitis pigmentosa
10.1080/13816810.2024.2414081 · 2025 · External reference
Suppression of microglial activation is neuroprotective in a mouse model of human retinitis pigmentosa
10.1523/jneurosci.5200-13.2014 · 2014 · External reference
Relationship between aqueous flare and visual function in retinitis pigmentosa
10.1016/j.ajo.2015.02.001 · 2015 · External reference
Clinical evidence of sustained chronic inflammatory reaction in retinitis pigmentosa
10.1016/j.ophtha.2012.07.006 · 2013 · External reference
Correlation between aqueous flare and residual visual field area in retinitis pigmentosa
10.1136/bjophthalmol-2018-312225 · 2019 · External reference
Aqueous flare and progression of visual field loss in patients with retinitis pigmentosa
10.1167/iovs.61.8.26 · 2020 · External reference
C-Reactive protein and progression of vision loss in retinitis pigmentosa
10.1111/aos.13502 · 2018 · External reference
Changes of serum inflammatory molecules and their relationships with visual function in Retinitis pigmentosa
10.1167/iovs.61.11.30 · 2020 · External reference
Circulating inflammatory monocytes oppose microglia and contribute to cone cell death in retinitis pigmentosa
10.1093/pnasnexus/pgac003 · 2022 · External reference
Microglial phagocytosis of living photoreceptors contributes to inherited retinal degeneration
10.15252/emmm.201505298 · 2015 · External reference
Microglial function is distinct in different anatomical locations during retinal homeostasis and degeneration
10.1016/j.immuni.2019.02.007 · 2019 · External reference
Monocytes in retinal degeneration: little cells with a big impact
10.1007/978-3-031-76550-6_22 · 2025 · External reference
Peripheral monocytes and neutrophils promote photoreceptor cell death in an experimental retinal detachment model
10.1038/s41419-023-06350-6 · 2023 · External reference
Microglia versus monocytes: distinct roles in degenerative diseases of the retina
10.1016/j.tins.2020.03.012 · 2020 · External reference
Microglia regulate neuroglia remodeling in various ocular and retinal injuries
10.4049/jimmunol.1800982 · 2019 · External reference
Role of fractalkine/CX3CR1 interaction in light-induced photoreceptor degeneration through regulating retinal microglial activation and migration
10.1371/journal.pone.0035446 · 2012 · External reference
C3- and CR3-dependent microglial clearance protects photoreceptors in retinitis pigmentosa
10.1084/jem.20190009 · 2019 · External reference
Microglia at sites of atrophy restrict the progression of retinal degeneration via Galectin-3 and Trem2 interactions
2023 · External reference
Microglia modulation by TGF-beta1 protects cones in mouse models of retinal degeneration
2020 · External reference
Permanent neuroglial remodeling of the retina following infiltration of CSF1R inhibition-resistant peripheral monocytes
10.1073/pnas.1807123115 · 2018 · External reference
The role of microglia and peripheral monocytes in retinal damage after corneal chemical injury
10.1016/j.ajpath.2018.03.005 · 2018 · External reference
Study protocol for a prospective natural history registry investigating the relationships between inflammatory markers and disease progression in retinitis pigmentosa: the RP-PRIMARY study
10.1007/s10384-025-01179-2 · 2025 · External reference
Baseline relationships between visual function and inflammatory markers in the registry of moderated-stage retinitis pigmentosa
10.1016/j.xops.2025.100930 · 2026 · External reference
Assessment of central visual function in patients with retinitis pigmentosa
10.1038/s41598-018-26231-9 · 2018 · External reference
Clinical characteristics and natural history of rho-associated retinitis pigmentosa: a long-term Follow-Up Study
10.1097/iae.0000000000002808 · 2021 · External reference
Genetics, clinical characteristics, and natural history of PDE6B-Associated retinal dystrophy
10.1016/j.ajo.2024.02.005 · 2024 · External reference
PDE6A-Associated retinitis pigmentosa, clinical characteristics, genetics, and natural history
10.1016/j.oret.2024.08.018 · 2025 · External reference
Central retinal sensitivity decline in RPGR-Related retinal phenotypes
10.1016/j.ajo.2025.11.002 · 2026 · External reference
Natural history of retinitis pigmentosa based on genotype, vitamin A/E supplementation, and an electroretinogram biomarker
10.1172/jci.insight.167546 · 2023 · External reference
Clinical characteristics of EYS-associated retinal dystrophy in 291 Japanese patients
10.1038/s41525-025-00541-0 · 2025 · External reference
Establishing clinical trial endpoints in selecting patients for RPGR retinal gene therapy
10.1167/tvst.13.9.18 · 2024 · External reference
Long-term natural history of ellipsoid zone width in USH2A-retinopathy
10.1136/bjo-2024-325323 · 2025 · External reference
EYS mutations causing autosomal recessive Retinitis pigmentosa: changes of retinal structure and function with disease progression
10.3390/genes8070178 · 2017 · External reference
Multimodal structural disease progression of retinitis pigmentosa according to mode of inheritance
10.1038/s41598-019-47251-z · 2019 · External reference
Progression rate of visual function and affecting factors at different stages of retinitis pigmentosa
10.1155/2022/7204954 · 2022 · External reference
Ocular and serum profiles of inflammatory molecules associated with retinitis pigmentosa
10.1167/tvst.13.8.18 · 2024 · External reference
Retinal inflammation, cell death and inherited retinal dystrophies
10.3390/ijms22042096 · 2021 · External reference
Laser flare photometry: a noninvasive, objective, and quantitative method to measure intraocular inflammation
10.1007/s10792-009-9310-2 · 2010 · External reference
Aqueous flare in retinitis pigmentosa
10.1007/s004170050101 · 1998 · External reference
Dynamic inner blood retina barrier disruption in Retinitis pigmentosa
10.1167/iovs.66.15.61 · 2025 · External reference
Predicting blood loss and transfusion requirement in patients undergoing surgery for musculoskeletal tumors
10.1111/trf.12532 · 2014 · External reference
Randomized study of basal-bolus insulin therapy in the inpatient management of patients with type 2 diabetes undergoing general surgery (RABBIT 2 surgery)
10.2337/dc10-1407 · 2011 · External reference
Paleontology. Warm-blooded "sea dragons"?
10.1126/science.1191409 · 2010 · External reference
Effect of gene therapy on visual function in Leber's congenital amaurosis
10.1056/nejmoa0802268 · 2008 · External reference
Protocol for NAC Attack, a phase-3, multicenter randomized, parallel, double masked, placebo controlled trial evaluating the efficacy and safety of oral N-acetylcysteine (NAC) in patients with retinitis pigmentosa
2025 · External reference
Endpoints and design for clinical trials in USH2A-Related retinal degeneration: results and recommendations from the RUSH2A natural history Study
10.1167/tvst.13.10.15 · 2024 · External reference
Safety and efficacy of MCO-010 optogenetic therapy in patients with Stargardt disease in USA (STARLIGHT): an open-label multi-center Ph2 trial
10.1016/j.eclinm.2025.103430 · 2025 · External reference
Topical isopropyl unoprostone for retinitis pigmentosa: microperimetric results of the phase 2 clinical study
10.1007/s40123-012-0005-9 · 2012 · External reference
Comparison of microperimetry and static perimetry for evaluating macular function and progression in Retinitis pigmentosa
10.1016/j.xops.2024.100582 · 2024 · External reference
Therapeutic efficacy of topical unoprostone isopropyl in retinitis pigmentosa
10.1111/aos.12293 · 2014 · External reference
