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References from A nucleus-associated miR-661-C/EBPα-PPARγ regulatory axis skews BMSC lineage commitment in SONFH. Local targets link to admitted publications; unresolved targets remain external evidence.
Decreased osteogenic activity of mesenchymal stem cells in patients with corticosteroid-induced osteonecrosis of the femoral head
10.1016/j.arth.2015.08.017 · 2016 · External reference
Glucocorticoids induce osteonecrosis of the femoral head: association with dysfunction of bone marrow mesenchymal stem cells
2021 · External reference
β-catenin inhibition disrupts osteogenic/adipogenic homeostasis leading to glucocorticoid-induced osteonecrosis of the femoral head
10.7554/elife.92469.3 · 2024 · External reference
Advances in the pathogenesis of steroid-associated osteonecrosis of the femoral head
10.3390/biom14060667 · 2024 · External reference
C/EBPα regulates BMSC fate and steroid-induced avascular necrosis by targeting the PPARγ pathway
10.1186/s13287-022-03027-3 · 2022 · External reference
miR-129-5p targets HOXC10 to control BMSC adipogenesis and osteogenesis in a model of steroid-induced osteonecrosis of the femoral head
10.62347/chgj7909 · 2024 · External reference
MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
10.1002/stem.288 · 2010 · External reference
MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
10.1172/jci77716 · 2015 · External reference
miR-27a attenuates adipogenesis and promotes osteogenesis of steroid-induced rat BMSCs by targeting PPARγ and GREM1
10.1038/srep38491 · 2016 · External reference
MiR-708 promotes steroid-induced osteonecrosis of femoral head and suppresses osteogenic differentiation by targeting SMAD3
10.1038/srep22599 · 2016 · External reference
Nuclear functions of mammalian microRNAs in gene regulation, immunity and cancer
10.1186/s12943-018-0765-5 · 2018 · External reference
miRNA goes nuclear
10.4161/rna.19354 · 2012 · External reference
MicroRNA-373 induces expression of genes with complementary promoter sequences
10.1073/pnas.0707594105 · 2008 · External reference
Small dsRNAs induce transcriptional activation in human cells
10.1073/pnas.0607015103 · 2006 · External reference
Inducing gene expression by targeting promoter sequences using small activating RNAs (saRNAs)
2015 · External reference
Nuclear role for human Argonaute-1 as an estrogen-receptor coactivator at enhancers
10.1083/jcb.201908097 · 2020 · External reference
Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus
10.1261/rna.034769.112 · 2013 · External reference
Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs
10.1093/nar/gkad1155 · 2024 · External reference
Nuclear Argonaute:miRNA complexes recognize target sequences within chromatin-associated RNA and silence gene expression
10.1093/nar/gkaf800 · 2025 · External reference
MicroRNA-mediated interacting circuits predict hypoxia and inhibited Wnt signaling in human osteonecrosis of femoral head
10.1007/s00264-018-3895-x · 2018 · External reference
MicroRNA expression in bone marrow mesenchymal stem cells from mice with steroid-induced osteonecrosis of the femoral head
10.3892/mmr.2015.4386 · 2015 · External reference
LncRNA expression profiling of BMSCs in osteonecrosis of the femoral head associates with abnormal adipogenic/osteogenic transdifferentiation
10.1038/s41598-018-27501-2 · 2018 · External reference
Emerging roles of long non-coding RNAs in osteonecrosis of the femoral head
2020 · External reference
Involvement of the long noncoding RNA H19 in osteogenic differentiation and bone regeneration
10.1186/s13287-021-02149-4 · 2021 · External reference
Histone deacetylase activity and epigenetic regulation of MSC osteogenesis/adipogenesis: implications for steroid-induced osteonecrosis
2024 · External reference
Identification of miPEP133, a tumor-suppressor microprotein encoded by pri-miR-34a
10.1186/s12943-020-01248-9 · 2020 · External reference
Drosophila primary microRNA-8 encodes a functional micropeptide (miPEP-8)
10.1186/s13059-021-02345-8 · 2021 · External reference
Functions of animal microRNA-encoded peptides: the race is on
10.15252/embr.202254789 · 2022 · External reference
Small activating RNAs toward new therapeutics
2021 · External reference
Treatment of HCV infection by targeting microRNA-122 with miravirsen
10.1056/nejmoa1209026 · 2013 · External reference
RNA therapeutics in kidney diseases: prospects and current status (includes anti-miR-21 lademirsen)
10.1093/ckj/sfaf214 · 2025 · External reference
Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation; anti-miR-214-3p promotes bone formation in mice
2016 · External reference
MicroRNAs involved in bone formation
2014 · External reference
A delivery system targeting bone resorption surfaces for microRNA modulators (D-Asp8-liposome)
2015 · External reference
MicroRNA-204 regulates Runx2 protein expression and mesenchymal progenitor cell differentiation
10.1002/stem.288 · ExternalCitation · doi-reference
MicroRNA-mediated interacting circuits predict hypoxia and inhibited Wnt signaling in human osteonecrosis of femoral head
10.1007/s00264-018-3895-x · ExternalCitation · doi-reference
Decreased osteogenic activity of mesenchymal stem cells in patients with corticosteroid-induced osteonecrosis of the femoral head
10.1016/j.arth.2015.08.017 · ExternalCitation · doi-reference
LncRNA expression profiling of BMSCs in osteonecrosis of the femoral head associates with abnormal adipogenic/osteogenic transdifferentiation
10.1038/s41598-018-27501-2 · ExternalCitation · doi-reference
MiR-708 promotes steroid-induced osteonecrosis of femoral head and suppresses osteogenic differentiation by targeting SMAD3
10.1038/srep22599 · ExternalCitation · doi-reference
miR-27a attenuates adipogenesis and promotes osteogenesis of steroid-induced rat BMSCs by targeting PPARγ and GREM1
10.1038/srep38491 · ExternalCitation · doi-reference
Treatment of HCV infection by targeting microRNA-122 with miravirsen
10.1056/nejmoa1209026 · ExternalCitation · doi-reference
Small dsRNAs induce transcriptional activation in human cells
10.1073/pnas.0607015103 · ExternalCitation · doi-reference
MicroRNA-373 induces expression of genes with complementary promoter sequences
10.1073/pnas.0707594105 · ExternalCitation · doi-reference
Nuclear role for human Argonaute-1 as an estrogen-receptor coactivator at enhancers
10.1083/jcb.201908097 · ExternalCitation · doi-reference
RNA therapeutics in kidney diseases: prospects and current status (includes anti-miR-21 lademirsen)
10.1093/ckj/sfaf214 · ExternalCitation · doi-reference
Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs
10.1093/nar/gkad1155 · ExternalCitation · doi-reference
Nuclear Argonaute:miRNA complexes recognize target sequences within chromatin-associated RNA and silence gene expression
10.1093/nar/gkaf800 · ExternalCitation · doi-reference
MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation
10.1172/jci77716 · ExternalCitation · doi-reference
Nuclear functions of mammalian microRNAs in gene regulation, immunity and cancer
10.1186/s12943-018-0765-5 · ExternalCitation · doi-reference
Identification of miPEP133, a tumor-suppressor microprotein encoded by pri-miR-34a
10.1186/s12943-020-01248-9 · ExternalCitation · doi-reference
Drosophila primary microRNA-8 encodes a functional micropeptide (miPEP-8)
10.1186/s13059-021-02345-8 · ExternalCitation · doi-reference
Involvement of the long noncoding RNA H19 in osteogenic differentiation and bone regeneration
10.1186/s13287-021-02149-4 · ExternalCitation · doi-reference
C/EBPα regulates BMSC fate and steroid-induced avascular necrosis by targeting the PPARγ pathway
10.1186/s13287-022-03027-3 · ExternalCitation · doi-reference
Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus
10.1261/rna.034769.112 · ExternalCitation · doi-reference
Functions of animal microRNA-encoded peptides: the race is on
10.15252/embr.202254789 · ExternalCitation · doi-reference
Advances in the pathogenesis of steroid-associated osteonecrosis of the femoral head
10.3390/biom14060667 · ExternalCitation · doi-reference
MicroRNA expression in bone marrow mesenchymal stem cells from mice with steroid-induced osteonecrosis of the femoral head
10.3892/mmr.2015.4386 · ExternalCitation · doi-reference
miRNA goes nuclear
10.4161/rna.19354 · ExternalCitation · doi-reference
miR-129-5p targets HOXC10 to control BMSC adipogenesis and osteogenesis in a model of steroid-induced osteonecrosis of the femoral head
10.62347/chgj7909 · ExternalCitation · doi-reference
β-catenin inhibition disrupts osteogenic/adipogenic homeostasis leading to glucocorticoid-induced osteonecrosis of the femoral head
10.7554/elife.92469.3 · ExternalCitation · doi-reference