Research graph
References from Bile acid and bacterial β-ADP-heptose induce gastric epithelial remodeling through the NF-κB–LIF axis. Local targets link to admitted publications; unresolved targets remain external evidence.
Gastric intestinal metaplasia: real culprit or innocent bystander as a precancerous condition for gastric cancer?
10.1053/j.gastro.2023.08.028 · 2023 · External reference
Decoding inflammatory mediators in the Correa's cascade: from chronic gastritis to carcinogenesis and targeted therapies
10.1016/j.intimp.2025.115191 · 2025 · External reference
Advances and challenges in gastric cancer testing: the role of biomarkers
2025 · External reference
Gastric cancer
10.1016/s0140-6736(25)00052-2 · 2025 · External reference
Helicobacter pylori and gastric cancer: mechanisms and new perspectives
10.1186/s13045-024-01654-2 · 2025 · External reference
Stomach microbiota in gastric cancer development and clinical implications
10.1136/gutjnl-2024-332815 · 2024 · External reference
ALPK1- and TIFA-dependent innate immune response triggered by the Helicobacter pylori type IV secretion system
10.1016/j.celrep.2017.08.039 · 2017 · External reference
ADP-heptose: a bacterial PAMP detected by the host sensor ALPK1
10.1007/s00018-020-03577-w · 2021 · External reference
The ALPK1/TIFA/NF-κB axis links a bacterial carcinogen to R-loop-induced replication stress
10.1038/s41467-020-18857-z · 2020 · External reference
Bacterial ADP-heptose triggers stem cell regeneration in the intestinal epithelium following injury
10.1016/j.stem.2025.06.009 · 2025 · External reference
The causal role of bile acids in cancers of the digestive system
10.3390/biomedicines14030598 · 2026 · External reference
Bile reflux and bile acids in the progression of gastric intestinal metaplasia
10.1097/cm9.0000000000002290 · 2022 · External reference
Bile reflux alters the profile of the gastric mucosa microbiota
10.3389/fcimb.2022.940687 · 2022 · External reference
Exploration of gastric carcinogenesis from the relationship between bile acids and intestinal metaplasia and intragastric microorganisms (H. pylori and non-H. pylori)
10.1007/s00432-023-05407-5 · 2023 · External reference
Iron deficiency linked to altered bile acid metabolism promotes helicobacter pylori-induced inflammation-driven gastric carcinogenesis
10.1172/jci147822 · 2022 · External reference
MicroRNA-92a-1-5p increases CDX2 by targeting FOXD1 in bile acids-induced gastric intestinal metaplasia
10.1136/gutjnl-2017-315318 · 2019 · External reference
Interplay between bile acids and the gut microbiota promotes intestinal carcinogenesis
10.1002/mc.22999 · 2019 · External reference
The somatic mutation landscape of normal gastric epithelium
10.1038/s41586-025-08708-6 · 2025 · External reference
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro
10.1016/j.stem.2009.11.013 · 2010 · External reference
Cellular plasticity, reprogramming, and regeneration: metaplasia in the stomach and beyond
10.1053/j.gastro.2021.10.036 · 2022 · External reference
Gastric carcinogenesis and the cancer stem cell hypothesis
10.1007/s10120-009-0537-4 · 2010 · External reference
Dissecting the spatial and single-cell transcriptomic architecture of cancer stem cell niche driving tumor progression in gastric cancer
2025 · External reference
Leukemia inhibitory factor: an important cytokine in pathologies and cancer
10.3390/biom12020217 · 2022 · External reference
LIF/LIFR signaling in gastric cancer: a double-edged sword in tumor progression and therapeutic resistance
10.1002/cam4.71315 · 2025 · External reference
TGF-β-driven LIF expression influences neutrophil extracellular traps (NETs) and contributes to peritoneal metastasis in gastric cancer
10.1038/s41419-024-06594-w · 2024 · External reference
Enhanced LRP8 expression induced by Helicobacter pylori drives gastric cancer progression by facilitating β-Catenin nuclear translocation
10.1016/j.jare.2024.04.002 · 2025 · External reference
Generation of human antral and fundic gastric organoids from pluripotent stem cells
10.1038/s41596-018-0080-z · 2019 · External reference
Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose
10.1038/s41586-018-0433-3 · 2018 · External reference
Classification and grading of gastritis. The updated Sydney system. International workshop on the histopathology of gastritis, houston 1994
10.1097/00000478-199610000-00001 · 1996 · External reference
Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression
10.1016/j.ccell.2023.10.004 · 2023 · External reference
Helicobacter pylori, microbiota and gastric cancer - principles of microorganism-driven carcinogenesis
10.1038/s41575-025-01042-2 · 2025 · External reference
Integrative proteogenomics maps multifactorial aetiology, progression and therapeutic vulnerabilities in gastric cancer
10.1136/gutjnl-2025-337247 · 2026 · External reference
Tff2 marks gastric corpus progenitors that give rise to pyloric metaplasia/SPEM following injury
10.1136/gutjnl-2025-337839 · 2026 · External reference
TFF2, a MUC6-binding lectin stabilizing the gastric mucus barrier and more
10.3892/ijo.2015.3090 · 2015 · External reference
Epithelial SOX9 drives progression and metastases of gastric adenocarcinoma by promoting immunosuppressive tumour microenvironment
10.1136/gutjnl-2021-326581 · 2023 · External reference
Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis
10.1016/j.bcp.2024.116134 · 2024 · External reference
LIF promotes Sec15b-Mediated STAT3 exosome secretion to maintain stem cell pluripotency in mouse embryonic development
2024 · External reference
Inflammation and metabolism in tissue repair and regeneration
10.1126/science.aam7928 · 2017 · External reference
