Research graph
References from Fungal hyphae through the lens of microfluidic devices: From biological properties to novel therapeutic opportunities. Local targets link to admitted publications; unresolved targets remain external evidence.
Build your own soil: exploring microfluidics to create microbial habitat structures
10.1038/ismej.2017.184 · 2018 · External reference
Fungal foraging behaviour and hyphal space exploration in micro-structured soil chips
10.1038/s41396-020-00886-7 · 2021 · External reference
Mechanisms and virulence factors of Cryptococcus neoformans dissemination to the central nervous system
2024 · External reference
Habitat geometry in artificial microstructure affects bacterial and fungal growth, interactions, and substrate degradation
10.1038/s42003-021-02736-4 · 2021 · External reference
Habitat complexity affects microbial growth in fractal maze
10.1016/j.cub.2023.02.064 · 2023 · External reference
Microfluidic monitoring of the growth of individual hyphae in confined environments
10.1098/rsos.191535 · 2020 · External reference
A compartmentalized microsystem helps understanding the uptake of benzo[a]pyrene by fungi during soil bioremediation processes
10.1016/j.scitotenv.2021.147151 · 2021 · External reference
The world of hyphae
10.1016/j.fgb.2025.104033 · 2025 · External reference
Microfabrication and its use in investigating fungal biology
10.1111/mmi.14816 · 2022 · External reference
Long-distance early endosome motility in Aspergillus fumigatus promotes normal hyphal growth behaviors in controlled microenvironments but is dispensable for virulence
10.1111/tra.12735 · 2020 · External reference
Bronchial epithelial cells on the front line to fight lung infection-causing Aspergillus fumigatus
10.3389/fimmu.2020.01041 · 2020 · External reference
Hyphal growth in human fungal pathogens and its role in virulence
10.1155/2012/517529 · 2012 · External reference
Hyphal orientation of Candida albicans is regulated by a calcium-dependent mechanism
10.1016/j.cub.2006.12.043 · 2007 · External reference
An internal polarity landmark is important for externally induced hyphal behaviors in Candida albicans
10.1128/ec.00453-07 · 2008 · External reference
Secreted aspartic proteinases: key factors in Candida infections and host-pathogen interactions
10.3390/ijms25094775 · 2024 · External reference
Pseudohyphal growth of the emerging pathogen Candida auris is triggered by genotoxic stress through the S phase checkpoint
10.1128/msphere.00151-20 · 2020 · External reference
Highly parallel bending tests for fungal hyphae enabled by two-photon polymerization of microfluidic mold
10.3389/fbioe.2024.1449167 · 2024 · External reference
The clock in growing hyphae and their synchronization in Neurospora crassa
10.1038/s42003-024-06429-6 · 2024 · External reference
Visualizing liquid distribution across hyphal networks with cellular resolution
10.1063/5.0231656 · 2024 · External reference
Chapter 15 - the immune system and the microbiota: the two sides of mucosal tolerance
2022 · External reference
Bending stiffness of Candida albicans hyphae as a proxy of cell wall properties
10.1039/d2lc00219a · 2022 · External reference
Cryptococcosis-a systematic review to inform the World Health Organization Fungal Priority Pathogens List
2024 · External reference
Co-infection with Staphylococcus aureus after primary influenza virus infection leads to damage of the endothelium in a human alveolus-on-a-chip model
10.1088/1758-5090/ab7073 · 2020 · External reference
Synergistic effects of soil microstructure and bacterial EPS on drying rate in emulated soil micromodels
10.1016/j.soilbio.2014.12.006 · 2015 · External reference
Neutrophil interactions stimulate evasive hyphal branching by Aspergillus fumigatus
10.1371/journal.ppat.1006154 · 2017 · External reference
Hide, keep quiet, and keep low: properties that make Aspergillus fumigatus a successful lung pathogen
10.3389/fmicb.2016.00438 · 2016 · External reference
Penetration of the human pulmonary epithelium by Aspergillus fumigatus hyphae
10.1093/infdis/jiy298 · 2018 · External reference
Trade-off between plasticity and velocity in mycelial growth
10.1128/mbio.03196-20 · 2021 · External reference
Compartmentalized microchannel array for high-throughput analysis of single cell polarized growth and dynamics
10.1038/srep16111 · 2015 · External reference
A versatile microfluidic platform measures hyphal interactions between Fusarium graminearum and Clonostachys rosea in real-time
10.1038/s42003-021-01767-1 · 2021 · External reference
One hundred years of the Spitzenkorper: a story in three acts
10.1016/j.fgb.2025.104036 · 2025 · External reference
Receptor-mediated signaling in Aspergillus fumigatus
10.3389/fmicb.2013.00026 · 2013 · External reference
The stiffness of living tissues and its implications for tissue engineering
10.1038/s41578-019-0169-1 · 2020 · External reference
Monitoring the impact of confinement on hyphal penetration and fungal behavior
10.1371/journal.pone.0312855 · 2024 · External reference
Fungi use efficient algorithms for the exploration of microfluidic networks
10.1002/smll.200600105 · 2006 · External reference
Pseudomonas strains induce transcriptional and morphological changes and reduce root colonization of Verticillium spp
10.3389/fmicb.2021.652468 · 2021 · External reference
The rise of fungal G-protein coupled receptors in pathogenesis and symbiosis
10.1371/journal.ppat.1013212 · 2025 · External reference
Unresolved reference
2009 · External reference
Microfluidics structures for probing the dynamic behaviour of filamentous fungi
10.1016/j.mee.2009.11.096 · 2010 · External reference
Probing the growth dynamics of Neurospora crassa with microfluidic structures
10.1016/j.funbio.2011.02.003 · 2011 · External reference
Intracellular mechanisms of fungal space searching in microenvironments
10.1073/pnas.1816423116 · 2019 · External reference
Immune cell paracrine signaling drives the neutrophil response to A. fumigatus in an infection-on-a-chip model
10.1007/s12195-020-00655-8 · 2021 · External reference
Invasive aspergillosis-on-chip: a quantitative treatment study of human Aspergillus fumigatus infection
10.1016/j.biomaterials.2022.121420 · 2022 · External reference
Crowdsourced analysis of fungal growth and branching on microfluidic platforms
10.1371/journal.pone.0257823 · 2021 · External reference
A microfluidic device for simultaneous detection of enzyme secretion and elongation of a single hypha
10.3389/fmicb.2023.1125760 · 2023 · External reference
Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis
10.4103/atm.atm_231_16 · 2017 · External reference
LumeNEXT: a practical method to pattern luminal structures in ECM gels
10.1002/adhm.201500608 · 2016 · External reference
Human neutrophils are primed by chemoattractant gradients for blocking the growth of Aspergillus fumigatus
10.1093/infdis/jiv419 · 2016 · External reference
Bifunctional small molecules enhance neutrophil activities against Aspergillus fumigatus in vivo and in vitro
10.3389/fimmu.2019.00644 · 2019 · External reference
Trans-cellular tunnels induced by the fungal pathogen Candida albicans facilitate invasion through successive epithelial cells without host damage
10.1038/s41467-022-31237-z · 2022 · External reference
In vitro infection models to study fungal-host interactions
10.1093/femsre/fuab005 · 2021 · External reference
Spiral-based microfluidic device for long-term time course imaging of Neurospora crassa with single nucleus resolution
10.1016/j.fgb.2016.06.004 · 2016 · External reference
A guide to the organ-on-a-chip
10.1038/s43586-022-00118-6 · 2022 · External reference
Candida auris infections
10.1056/nejmra2402635 · 2024 · External reference
New approach methodologies for drug discovery
10.1016/j.cell.2026.02.012 · 2026 · External reference
Organs-on-chips: into the next decade
10.1038/s41573-020-0079-3 · 2021 · External reference
Microfluidic chips provide visual access to in situ soil ecology
10.1038/s42003-021-02379-5 · 2021 · External reference
Exposure to polystyrene nanoplastics reduces bacterial and fungal biomass in microfabricated soil models
10.1016/j.scitotenv.2023.166503 · 2023 · External reference
Hyphal growth determines spatial organization and coexistence in a pathogenic polymicrobial community in a spatially structured environment
10.1093/ismejo/wraf279 · 2025 · External reference
Saprotrophy-to-symbiosis continuum in fungi
10.1016/j.cub.2025.01.032 · 2025 · External reference
Surface optimization governs the local design of physical networks
10.1038/s41586-025-09784-4 · 2026 · External reference
Cell wall remodeling in a fungal pathogen is required for hyphal growth into microspaces
10.1128/mbio.01184-25 · 2025 · External reference
Increasing access to microfluidics for studying fungi and other branched biological structures
10.1186/s40694-019-0071-z · 2019 · External reference
Fungal pathogens: shape-shifting invaders
10.1016/j.tim.2020.05.001 · 2020 · External reference
Hierarchical structure of the program used by filamentous fungi to navigate in confining microenvironments
2025 · External reference
Critical parameters of fungal pathogenicity at the epithelial interphase
10.1093/femsml/uqag001 · 2026 · External reference
Genetic polymorphisms affecting IDO1 or IDO2 activity differently associate with aspergillosis in humans
10.3389/fimmu.2019.00890 · 2019 · External reference
Fungal evolution: major ecological adaptations and evolutionary transitions
10.1111/brv.12510 · 2019 · External reference
Looking outside the box: a comparative cross-kingdom view on the cell biology of the three major lineages of eukaryotic multicellular life
10.1007/s00018-023-04843-3 · 2023 · External reference
One population, multiple lifestyles: commensalism and pathogenesis in the human mycobiome
10.1016/j.chom.2023.02.010 · 2023 · External reference
Raman spectroscopy in microfluidic chips reveals hyphal scale stress-associated metabolic responses in filamentous soil fungi
10.1016/j.funbio.2026.101749 · 2026 · External reference
Mechanical force-induced morphology changes in a human fungal pathogen
10.1186/s12915-020-00833-0 · 2020 · External reference
Microfluidically supported biochip design for culture of endothelial cell layers with improved perfusion conditions
10.1088/1758-5090/7/1/015013 · 2015 · External reference
Pathogenic fungal sensing and responses to stressful host environments
10.1146/annurev-micro-051024-033116 · 2025 · External reference
Fungi-on-a-chip: microfluidic platforms for single-cell studies on fungi
10.1093/femsre/fuac039 · 2022 · External reference
Transcription activator-like effector protects bacterial endosymbionts from entrapment within fungal hyphae
10.1016/j.cub.2023.05.028 · 2023 · External reference
AMF-SporeChip provides new insights into arbuscular mycorrhizal fungal asymbiotic hyphal growth dynamics at the cellular level
10.1039/d3lc00859b · 2024 · External reference
A compartmentalized neuron-oligodendrocyte co-culture device for myelin research: design, fabrication and functionality testing
10.1088/1361-6439/ab16a7 · 2019 · External reference
Snooping helices: the elastic path finding algorithm of growing hyphae
10.1073/pnas.2526262123 · 2026 · External reference
Commensalism and pathogenesis of Candida albicans at the mucosal interface
10.1038/s41579-025-01174-x · 2025 · External reference
Bidirectional propagation of signals and nutrients in fungal networks via specialized hyphae
10.1016/j.cub.2018.11.058 · 2019 · External reference
Host cell invasion by medically important fungi
2014 · External reference
Mucin biopolymers and their barrier function at airway surfaces
10.1021/acs.langmuir.0c02410 · 2020 · External reference
Pore-scale monitoring of the effect of microarchitecture on fungal growth in a two-dimensional soil-like micromodel
2018 · External reference
Probing bacterial-fungal interactions at the single cell level
10.1039/c4ib00154k · 2014 · External reference
Soil-on-a-chip: microfluidic platforms for environmental organismal studies
10.1039/c5lc01285f · 2016 · External reference
Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea
10.1111/mmi.14277 · 2019 · External reference
Microfluidic platform for integrated compartmentalization of single zoospores, germination and measurement of protrusive force generated by germ tubes
10.1039/d0lc00752h · 2020 · External reference
Platforms for high-throughput screening and force measurements on fungi and oomycetes
2021 · External reference
An elastomeric micropillar platform for the study of protrusive forces in hyphal invasion
10.1039/c7lc00725f · 2017 · External reference
Combining microfluidics and RNA-sequencing to assess the inducible defensome of a mushroom against nematodes
10.1186/s12864-019-5607-3 · 2019 · External reference
Contact-induced apical asymmetry drives the thigmotropic responses of Candida albicans hyphae
10.1111/cmi.12369 · 2015 · External reference
High frame-rate resolution of cell division during Candida albicans filamentation
10.1016/j.fgb.2016.02.001 · 2016 · External reference
Microfluidic live-cell imaging of Aspergillus fumigatus and Candida albicans hyphal growth treated with AmBisome and Caspofungin
10.1111/jmi.70053 · 2026 · External reference
Microfluidics and metabolomics reveal symbiotic bacterial-fungal interactions between Mortierella elongata and Burkholderia include metabolite exchange
10.3389/fmicb.2019.02163 · 2019 · External reference
Aspergillus fumigatus morphology and dynamic host interactions
10.1038/nrmicro.2017.90 · 2017 · External reference
Aspergillus fumigatus biology, immunopathogenicity and drug resistance
10.1038/s41579-025-01180-z · 2025 · External reference
Caspofungin treatment of aspergillus fumigatus results in ChsG-dependent upregulation of chitin synthesis and the formation of chitin-rich microcolonies
10.1128/aac.00862-15 · 2015 · External reference
Blood-brain barrier injury and neuroinflammation induced by SARS-CoV-2 in a lung-brain microphysiological system
10.1038/s41551-023-01054-w · 2024 · External reference
Reimagining human-centric drug development with new approach methodologies
10.1126/science.aeb0045 · 2026 · External reference
Hyphae of the fungus Aspergillus nidulans demonstrate chemotropism to nutrients and pH
10.1371/journal.pbio.3002726 · 2024 · External reference
Unresolved reference
External reference
Recent advances in microfluidic devices for bacteria and fungus research
10.1016/j.trac.2018.12.024 · 2019 · External reference
A 3D Fusarium keratitis model reveals isolate-specific adhesion and invasion properties in the Fusarium solani species complex
10.1128/msphere.00328-25 · 2025 · External reference