Research graph
References from Recent advances in the role of RhoA signaling in the heart. Local targets link to admitted publications; unresolved targets remain external evidence.
A novel ras-related gene family
10.1016/0092-8674(85)90058-3 · 1985 · External reference
Rho GTPases in cell biology
10.1038/nature01148 · 2002 · External reference
Rho signaling research: history, current status and future directions
10.1002/1873-3468.13087 · 2018 · External reference
Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells
10.1146/annurev.biochem.68.1.459 · 1999 · External reference
The RHO family GTPases: mechanisms of regulation and signaling
10.3390/cells10071831 · 2021 · External reference
A current overview of RhoA, RhoB, and RhoC functions in vascular biology and pathology
10.1016/j.bcp.2022.115321 · 2022 · External reference
Guanine nucleotide exchange factors for Rho GTPases (RhoGEFs) as oncogenic effectors and strategic therapeutic targets in metastatic cancer
10.1016/j.cellsig.2023.110749 · 2023 · External reference
The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors
10.1016/0092-8674(92)90163-7 · 1992 · External reference
Regulation of RhoGEF proteins by G12/13-coupled receptors
10.1111/j.1476-5381.2009.00121.x · 2009 · External reference
G protein-coupled receptor and RhoA-stimulated transcriptional responses: links to inflammation, differentiation, and cell proliferation
10.1124/mol.115.097857 · 2015 · External reference
Coupling of the thrombin receptor to G12 may account for selective effects of thrombin on gene expression and DNA synthesis in 1321N1 astrocytoma cells
10.1091/mbc.7.11.1679 · 1996 · External reference
Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3
10.1074/jbc.m104441200 · 2001 · External reference
Induction of the matricellular protein CCN1 through RhoA and MRTF-A contributes to ischemic cardioprotection
10.1016/j.yjmcc.2014.07.017 · 2014 · External reference
Angiotensin II activates RhoA in cardiac myocytes: a critical role of RhoA in angiotensin II-induced premyofibril formation
10.1161/01.res.82.6.666 · 1998 · External reference
Selective coupling of the S1P3 receptor subtype to S1P-mediated RhoA activation and cardioprotection
10.1016/j.yjmcc.2016.12.008 · 2017 · External reference
Prevention of RhoA activation and cofilin-mediated actin polymerization mediates the antihypertrophic effect of adenosine receptor agonists in angiotensin II- and endothelin-1-treated cardiomyocytes
10.1007/s11010-013-1832-2 · 2014 · External reference
Focal adhesion kinase as a RhoA-activable signaling scaffold mediating Akt activation and cardiomyocyte protection
10.1074/jbc.m804036200 · 2008 · External reference
Galpha(12/13) mediates alpha(1)-adrenergic receptor-induced cardiac hypertrophy
10.1161/01.res.0000043282.39776.7c · 2002 · External reference
Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13
10.1126/science.280.5372.2112 · 1998 · External reference
p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13
10.1126/science.280.5372.2109 · 1998 · External reference
Regulation of RGS-RhoGEFs by Galpha12 and Galpha13 proteins
10.1016/s0076-6879(04)90018-3 · 2004 · External reference
RhoGEF12 controls cardiac remodeling by integrating G protein- and integrin-dependent signaling cascades
10.1084/jem.20122126 · 2013 · External reference
G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure
10.1161/circulationaha.112.109256 · 2012 · External reference
Galpha q allosterically activates and relieves autoinhibition of p63RhoGEF
10.1016/j.cellsig.2010.03.006 · 2010 · External reference
A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors
10.1016/j.molcel.2012.10.018 · 2013 · External reference
Protein kinase C-alpha signals P115RhoGEF phosphorylation and RhoA activation in TNF-alpha-induced mouse brain microvascular endothelial cell barrier dysfunction
10.1186/1742-2094-8-28 · 2011 · External reference
Regulation of Rho guanine nucleotide exchange factor 3 by phosphorylation in the PH domain
10.1016/j.isci.2025.112753 · 2025 · External reference
Regulation of RhoA signaling by the cAMP-dependent phosphorylation of RhoGDIalpha
10.1074/jbc.m112.401547 · 2012 · External reference
Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes
10.1002/j.1460-2075.1996.tb00383.x · 1996 · External reference
Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif
10.1371/journal.pone.0008045 · 2009 · External reference
Mechanism of redox-mediated guanine nucleotide exchange on redox-active Rho GTPases
10.1074/jbc.m504768200 · 2005 · External reference
RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-kappaB activation
10.1016/j.freeradbiomed.2016.12.013 · 2017 · External reference
Revisited and revised: is RhoA always a villain in cardiac pathophysiology?
10.1007/s12265-010-9192-8 · 2010 · External reference
RhoA protects the mouse heart against ischemia/reperfusion injury
10.1172/jci44371 · 2011 · External reference
Mechanotransduction of rat aortic vascular smooth muscle cells requires RhoA and intact actin filaments
10.1161/01.res.85.1.5 · 1999 · External reference
RhoA/ROCK signaling is critical to FAK activation by cyclic stretch in cardiac myocytes
10.1152/ajpheart.00692.2004 · 2005 · External reference
Initiation and transduction of stretch-induced RhoA and Rac1 activation through caveolae: cytoskeletal regulation of ERK translocation
10.1074/jbc.m300725200 · 2003 · External reference
Yes-associated protein (YAP) mediates adaptive cardiac hypertrophy in response to pressure overload
10.1074/jbc.ra118.006123 · 2019 · External reference
Mechanotransduction: from the cell surface to the nucleus via RhoA
2019 · External reference
Rho guanine nucleotide exchange factors involved in cyclic-stretch-induced reorientation of vascular endothelial cells
2015 · External reference
ROCK-I and ROCK-II, two isoforms of Rho-associated coiled-coil forming protein serine/threonine kinase in mice
10.1016/0014-5793(96)00811-3 · 1996 · External reference
Rho kinases and cardiac remodeling
10.1253/circj.cj-16-0433 · 2016 · External reference
Novel insights into the roles of rho kinase in cancer
10.1007/s00005-015-0382-6 · 2016 · External reference
Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
10.1126/science.285.5429.895 · 1999 · External reference
Cooperation between mDia1 and ROCK in Rho-induced actin reorganization
10.1038/11056 · 1999 · External reference
Galpha12/13- and rho-dependent activation of phospholipase C-epsilon by lysophosphatidic acid and thrombin receptors
10.1124/mol.105.017921 · 2006 · External reference
Role of phospholipase Cepsilon in physiological phosphoinositide signaling networks
10.1016/j.cellsig.2012.01.009 · 2012 · External reference
PLCepsilon, PKD1, and SSH1L transduce RhoA signaling to protect mitochondria from oxidative stress in the heart
10.1126/scisignal.2004405 · 2013 · External reference
Control of actin reorganization by slingshot, a family of phosphatases that dephosphorylate ADF/cofilin
10.1016/s0092-8674(01)00638-9 · 2002 · External reference
Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes
10.1128/mcb.23.18.6597-6608.2003 · 2003 · External reference
Actin dynamics control SRF activity by regulation of its coactivator MAL
10.1016/s0092-8674(03)00278-2 · 2003 · External reference
RPEL motifs link the serum response factor cofactor MAL but not myocardin to Rho signaling via actin binding
10.1128/mcb.01623-07 · 2008 · External reference
The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration
10.1038/s41569-018-0063-3 · 2018 · External reference
Regulation of myocardial cell growth and death by the Hippo pathway
10.1253/circj.cj-16-0476 · 2016 · External reference
Targeting the Hippo pathway in heart repair
10.1093/cvr/cvab291 · 2022 · External reference
Regulation of the Hippo-YAP pathway by protease-activated receptors (PARs)
10.1101/gad.197582.112 · 2012 · External reference
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
10.1016/j.cell.2012.06.037 · 2012 · External reference
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein
10.1101/gad.2000111 · 2011 · External reference
Angiomotins link F-actin architecture to Hippo pathway signaling
10.1091/mbc.e13-11-0701 · 2014 · External reference
Pathophysiology of heart failure
10.1002/j.2040-4603.2016.tb00669.x · 2015 · External reference
Effects of a Rho kinase inhibitor on pressure overload induced cardiac hypertrophy and associated diastolic dysfunction
10.1152/ajpheart.01078.2007 · 2008 · External reference
Long-term inhibition of Rho-kinase suppresses angiotensin II-induced cardiovascular hypertrophy in rats in vivo: effect on endothelial NAD(P)H oxidase system
10.1161/01.res.0000096650.91688.28 · 2003 · External reference
Critical role of Rho-kinase pathway for cardiac performance and remodeling in failing rat hearts
10.1016/s0008-6363(02)00457-1 · 2002 · External reference
Chronic inhibition of Rho kinase blunts the process of left ventricular hypertrophy leading to cardiac contractile dysfunction in hypertension-induced heart failure
10.1016/s0022-2828(02)00278-x · 2003 · External reference
Long-term inhibition of Rho-kinase ameliorates diastolic heart failure in hypertensive rats
10.1097/fjc.0b013e31816533b7 · 2008 · External reference
Cardiac-specific overexpression of RhoA results in sinus and atrioventricular nodal dysfunction and contractile failure
10.1172/jci6842 · 1999 · External reference
RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis
10.1074/jbc.m604298200 · 2007 · External reference
RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis
10.1126/scisignal.2005262 · 2014 · External reference
RhoA rescues cardiac senescence by regulating Parkin-mediated mitophagy
10.1016/j.jbc.2023.102993 · 2023 · External reference
RhoA signaling increases mitophagy and protects cardiomyocytes against ischemia by stabilizing PINK1 protein and recruiting Parkin to mitochondria
10.1038/s41418-022-01032-w · 2022 · External reference
Heart disease mortality in the United States, 1970 to 2022
10.1161/jaha.124.038644 · 2025 · External reference
Cell death in the pathogenesis of heart disease: mechanisms and significance
10.1146/annurev.physiol.010908.163111 · 2010 · External reference
Historical perspective on the pathology of myocardial ischemia/reperfusion injury
10.1161/circresaha.113.300987 · 2013 · External reference
Inhibition of Rho-kinase protects the heart against ischemia/reperfusion injury
10.1016/j.cardiores.2003.12.004 · 2004 · External reference
High-density lipoproteins and their constituent, sphingosine-1-phosphate, directly protect the heart against ischemia/reperfusion injury in vivo via the S1P3 lysophospholipid receptor
10.1161/circulationaha.105.607135 · 2006 · External reference
Sphingosine 1-phosphate is an important endogenous cardioprotectant released by ischemic pre- and postconditioning
10.1152/ajpheart.00358.2009 · 2009 · External reference
Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease
10.1007/s00395-010-0112-5 · 2010 · External reference
Opposing roles of S1P(3) receptors in myocardial function
10.3390/cells9081770 · 2020 · External reference
Multiple cell death programs contribute to myocardial infarction
10.1161/circresaha.121.319584 · 2021 · External reference
Fundamental mechanisms of regulated cell death and implications for heart disease
10.1152/physrev.00022.2018 · 2019 · External reference
Cofilin activation mediates Bax translocation to mitochondria during excitotoxic neuronal death
10.1111/j.1471-4159.2011.07599.x · 2012 · External reference
Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
10.1016/s0092-8674(00)80405-5 · 1997 · External reference
Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II
10.1038/sj.cdd.4402285 · 2008 · External reference
Akt-GSK3beta-mPTP pathway regulates the mitochondrial dysfunction contributing to odontoblasts apoptosis induced by glucose oxidative stress
10.1038/s41420-022-00981-y · 2022 · External reference
Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury
10.1074/jbc.m112.436311 · 2013 · External reference
RhoA regulates Drp1 mediated mitochondrial fission through ROCK to protect cardiomyocytes
10.1016/j.cellsig.2018.06.012 · 2018 · External reference
The interplay between mitochondrial dynamics and mitophagy
10.1089/ars.2010.3779 · 2011 · External reference
The role of mitochondrial fission in cardiovascular health and disease
10.1038/s41569-022-00703-y · 2022 · External reference
The mechanisms and roles of selective autophagy in mammals
10.1038/s41580-022-00542-2 · 2023 · External reference
Deciphering the molecular signals of PINK1/Parkin mitophagy
10.1016/j.tcb.2016.05.008 · 2016 · External reference
Hippo pathway deficiency reverses systolic heart failure after infarction
10.1038/nature24045 · 2017 · External reference
Enhanced mitophagy mediated by the YAP/Parkin pathway protects against DOX-induced cardiotoxicity
10.1016/j.toxlet.2020.05.015 · 2020 · External reference
RHOA regulates mitochondria-ER contact sites through modulation of the VAPB/PTPIP51 tether
10.1038/s41467-025-66138-4 · 2025 · External reference
SEPTIN9 locally activates the RhoGEF ARHGEF18 to promote early stages of mitochondrial fission
10.1083/jcb.202406017 · 2025 · External reference
Mitochondrial stress activates YAP/TAZ through RhoA oxidation to promote liver injury
10.1038/s41419-024-06448-5 · 2024 · External reference
GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis
10.1038/s41467-023-43889-6 · 2023 · External reference
aYAP modRNA reduces cardiac inflammation and hypertrophy in a murine ischemia-reperfusion model
10.26508/lsa.201900424 · 2020 · External reference
Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model
10.1161/circresaha.115.303632 · 2014 · External reference
Hippo pathway effector Yap promotes cardiac regeneration
10.1073/pnas.1313192110 · 2013 · External reference
YAP partially reprograms chromatin accessibility to directly induce adult cardiogenesis in vivo
10.1016/j.devcel.2019.01.017 · 2019 · External reference
YAP induces a neonatal-like pro-renewal niche in the adult heart
10.1038/s44161-024-00428-w · 2024 · External reference
YAP overcomes mechanical barriers to induce mitotic rounding and adult cardiomyocyte division
10.1161/circulationaha.123.066004 · 2025 · External reference
Reappraising the role of inflammation in heart failure
10.1038/s41569-019-0315-x · 2020 · External reference
Targeting the NLRP3 inflammasome in cardiovascular diseases
2021 · External reference
YAP/TEAD1 complex is a default repressor of cardiac toll-like receptor genes
10.3390/ijms22136649 · 2021 · External reference
Long-term inhibition of Rho-kinase suppresses left ventricular remodeling after myocardial infarction in mice
10.1161/01.cir.0000127939.16111.58 · 2004 · External reference
Rho kinase activation plays a major role as a mediator of irreversible injury in reperfused myocardium
10.1152/ajpheart.01393.2006 · 2007 · External reference
Antianginal effects of hydroxyfasudil, a Rho-kinase inhibitor, in a canine model of effort angina
10.1038/sj.bjp.0704410 · 2001 · External reference
Different roles of myocardial ROCK1 and ROCK2 in cardiac dysfunction and postcapillary pulmonary hypertension in mice
10.1073/pnas.1721298115 · 2018 · External reference
FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2
10.1096/fj.12-217018 · 2013 · External reference
The function of Rho-associated kinases ROCK1 and ROCK2 in the pathogenesis of cardiovascular disease
10.3389/fphar.2015.00276 · 2015 · External reference
An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia
10.1172/jci122035 · 2019 · External reference
Drp1-dependent mitochondrial autophagy plays a protective role against pressure-overload induced mitochondrial dysfunction and heart failure
10.1161/circulationaha.115.020502 · 2016 · External reference
MRTF-A controls vessel growth and maturation by increasing the expression of CCN1 and CCN2
10.1038/ncomms4970 · 2014 · External reference
Cysteine-rich protein 61 (CCN1) deficiency alleviated cardiac remodeling in 5/6 nephrectomized mice by suppressing the MAPK signaling pathway
10.1155/cdr/6813183 · 2025 · External reference
Essential role for premature senescence of myofibroblasts in myocardial fibrosis
10.1016/j.jacc.2016.02.047 · 2016 · External reference
Cardiac fibrosis
10.1093/cvr/cvaa324 · 2021 · External reference
CTGF/CCN2 is an autocrine regulator of cardiac fibrosis
10.1016/j.yjmcc.2018.07.130 · 2018 · External reference
Disruption of actin dynamics regulated by Rho effector mDia1 attenuates pressure overload-induced cardiac hypertrophic responses and exacerbates dysfunction
10.1093/cvr/cvaa206 · 2021 · External reference
Targeting Rho-associated coiled-coil forming protein kinase (ROCK) in cardiovascular fibrosis and stiffening
10.1080/14728222.2020.1712593 · 2020 · External reference
Inhibition of Rho-kinase ameliorates myocardial remodeling and fibrosis in pressure overload and myocardial infarction: role of TGF-beta1-TAK1
10.1016/j.toxlet.2012.03.006 · 2012 · External reference
Belumosudil for chronic graft-versus-host disease after 2 or more prior lines of therapy: the ROCKstar study
10.1182/blood.2021012021 · 2021 · External reference
Novel highly selective ROCK2 inhibitor (TDI01) for the treatment of chronic graft-versus-host disease: a multicenter, open-label phase Ib/II study
2026 · External reference
Belumosudil, ROCK2-specific inhibitor, alleviates cardiac fibrosis by inhibiting cardiac fibroblasts activation
10.1152/ajpheart.00014.2022 · 2022 · External reference
Selective ROCK2 inhibition reduces microvascular obstruction but does not reduce myocardial infarction after ischaemia and reperfusion
2026 · External reference
YAP mediates compensatory cardiac hypertrophy through aerobic glycolysis in response to pressure overload
10.1172/jci150595 · 2022 · External reference
Yes-associated protein (YAP) facilitates pressure overload-induced dysfunction in the diabetic heart
10.1016/j.jacbts.2019.05.006 · 2019 · External reference
YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases
10.1172/jci143173 · 2021 · External reference
Cardiovascular aging and heart failure: JACC review topic of the week
10.1016/j.jacc.2019.06.053 · 2019 · External reference
Targeting age-related pathways in heart failure
10.1161/circresaha.119.315889 · 2020 · External reference
Parkin deficiency results in accumulation of abnormal mitochondria in aging myocytes
10.4161/cib.24511 · 2013 · External reference
Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule
10.1016/j.devcel.2024.04.020 · 2024 · External reference
The septic heart: current understanding of molecular mechanisms and clinical implications
10.1016/j.chest.2018.08.1037 · 2019 · External reference
Yap overexpression attenuates septic cardiomyopathy by inhibiting DRP1-related mitochondrial fission and activating the ERK signaling pathway
10.1080/10799893.2019.1641822 · 2019 · External reference
Role of inducible nitric oxide synthase in induction of RhoA expression in hearts from diabetic rats
10.1093/cvr/cvn095 · 2008 · External reference
Endotoxemia engages the RhoA kinase pathway to impair cardiac function by altering cytoskeleton, mitochondrial fission, and autophagy
10.1089/ars.2015.6421 · 2016 · External reference
Beneficial effect of intermedin 1-53 in septic shock rats: contributions of Rho kinase and BKCA pathway-mediated improvement in cardiac function
10.1097/shk.0000000000000639 · 2016 · External reference
Acute inhibition of Rho-kinase improves cardiac contractile function in streptozotocin-diabetic rats
10.1016/j.cardiores.2007.03.009 · 2007 · External reference
The Rho kinase inhibitor, fasudil, ameliorates diabetes-induced cardiac dysfunction by improving calcium clearance and actin remodeling
10.1007/s00109-016-1469-1 · 2017 · External reference
SGLT2 inhibitors and cardiac fibrosis: a comprehensive review
10.1016/j.cpcardiol.2025.103149 · 2025 · External reference
Empagliflozin ameliorates diabetic cardiomyopathy probably via activating AMPK/PGC-1alpha and inhibiting the RhoA/ROCK pathway
10.4239/wjd.v14.i12.1862 · 2023 · External reference
RhoA/Rho-kinase in the cardiovascular system
10.1161/circresaha.115.306532 · 2016 · External reference
YAP and TAZ in vascular smooth muscle confer protection against hypertensive vasculopathy
10.1161/atvbaha.121.317365 · 2022 · External reference
Post-transcriptional regulation of endothelial nitric oxide synthase mRNA stability by Rho GTPase
10.1074/jbc.273.37.24266 · 1998 · External reference
RhoA/Rho-kinase signaling in vascular smooth muscle and endothelium: mechanistic insights and translational implications in hypertension
10.3390/biom15111607 · 2025 · External reference
RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock
10.1038/ncomms7725 · 2015 · External reference
Vascular smooth muscle RhoA counteracts abdominal aortic aneurysm formation by modulating MAP4K4 activity
10.1038/s42003-022-04042-z · 2022 · External reference
RhoA accelerates atherosclerosis progression by interacting with Hspa5
10.1038/s41598-025-33741-w · 2026 · External reference
YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation
10.1172/jci93825 · 2017 · External reference
Emerging role of YAP/TAZ in vascular mechanotransduction and disease
10.1111/micc.12838 · 2024 · External reference
Fibroblast deletion of ROCK2 attenuates cardiac hypertrophy, fibrosis, and diastolic dysfunction
10.1172/jci.insight.93187 · 2017 · External reference
Loss of Yap/Taz in cardiac fibroblasts attenuates adverse remodelling and improves cardiac function
10.1093/cvr/cvab205 · 2022 · External reference
Blockade of fibroblast YAP attenuates cardiac fibrosis and dysfunction through MRTF-A inhibition
10.1016/j.jacbts.2020.07.009 · 2020 · External reference
Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction
10.1161/circresaha.110.223172 · 2010 · External reference
RhoA signaling in immune cell response and cardiac disease
10.3390/cells10071681 · 2021 · External reference
Macrophage/monocyte-specific deletion of Ras homolog gene family member A (RhoA) downregulates fractalkine receptor and inhibits chronic rejection of mouse cardiac allografts
10.1016/j.healun.2016.08.011 · 2017 · External reference
Macrophage-specific RhoA knockout delays Wallerian degeneration after peripheral nerve injury in mice
10.1186/s12974-021-02292-y · 2021 · External reference
RhoA deletion in macrophages/microglia aggravates blood-brain barrier disruption after ischemic stroke reperfusion injury by promoting endothelial cell apoptosis and pyroptosis
10.1016/j.nbd.2026.107279 · 2026 · External reference
Synovial macrophage rhoa protects against osteoarthritis by suppressing YAP/IL-17C mediated chondrocyte senescence
10.1007/s10565-026-10151-w · 2026 · External reference
Abstract P3086: regulation of Rhoa in myeloid cells on remodeling of the infarcted heart
10.1161/res.131.suppl_1.p3086 · 2022 · External reference
YAP/TAZ deficiency reprograms macrophage phenotype and improves infarct healing and cardiac function after myocardial infarction
10.1371/journal.pbio.3000941 · 2020 · External reference
Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress
10.1016/j.yjmcc.2023.05.004 · 2023 · External reference
AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis
10.1038/s41598-021-89989-5 · 2021 · External reference
YAP-driven malignant reprogramming of oral epithelial stem cells at single cell resolution
10.1038/s41467-024-55660-6 · 2025 · External reference
Cell type specificity of Hippo-YAP signaling in cardiac development and disease
10.1016/j.yjmcc.2025.08.003 · 2025 · External reference
