Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Adaptive rewiring of NADPH electron flow reveals escape routes from redox-balance-based growth coupling in Escherichia coli. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1007/978-3-642-86577-0
10.1007/978-3-642-86577-0 · External reference
Unresolved reference
External reference
Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
10.1038/191144a0 · 1961 · External reference
The soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coli
10.1074/jbc.m311657200 · 2004 · External reference
Energy conservation in chemotrophic anaerobic bacteria
10.1128/br.41.1.100-180.1977 · 1977 · External reference
Charges of nicotinamide adenine nucleotides and adenylate energy charge as regulatory parameters of the metabolism in Escherichia coli
10.1016/s0021-9258(17)40245-6 · 1977 · External reference
Redesign of the coenzyme specificity of a dehydrogenase by protein engineering
10.1038/343038a0 · 1990 · External reference
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli
10.1038/nchembio.186 · 2009 · External reference
Energetic efficiency of Escherichia coli: effects of mutations in components of the aerobic respiratory chain
10.1128/jb.175.10.3020-3025.1993 · 1993 · External reference
Analysis of Escherichia coli mutants with a linear respiratory chain
10.1371/journal.pone.0087307 · 2014 · External reference
Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity
10.1038/s41467-022-30877-5 · 2022 · External reference
Improvement of NADPH bioavailability in Escherichia coli by replacing NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase GapA with NADP+-dependent GapB from Bacillus subtilis and addition of NAD kinase
10.1007/s10295-013-1335-x · 2013 · External reference
Improvement of NADPH bioavailability in Escherichia coli through the use of phosphofructokinase deficient strains
10.1007/s00253-013-4859-0 · 2013 · External reference
Optimal cofactor swapping can increase the theoretical yield for chemical production in Escherichia coli and Saccharomyces cerevisiae
10.1016/j.ymben.2014.05.009 · 2014 · External reference
ATP drives direct photosynthetic production of 1-butanol in cyanobacteria
10.1073/pnas.1200074109 · 2012 · External reference
Selection of an endogenous 2,3-butanediol pathway in Escherichia coli by fermentative redox balance
10.1016/j.ymben.2016.11.012 · 2017 · External reference
Versatile selective evolutionary pressure using synthetic defect in universal metabolism
10.1038/s41467-021-27266-9 · 2021 · External reference
In silico design and adaptive evolution of Escherichia coli for production of lactic acid
10.1002/bit.20542 · 2005 · External reference
Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate
10.1002/bit.21694 · 2008 · External reference
Growth-coupled reverse β-oxidation enables redox-balanced fatty-alcohol fermentation and strain evolution
2026 · External reference
Development of a high-throughput, in vivo selection platform for NADPH-dependent reactions based on redox balance principles
10.1021/acssynbio.8b00179 · 2018 · External reference
A Growth-Based, High-Throughput Selection Platform Enables Remodeling of 4-Hydroxybenzoate Hydroxylase Active Site
10.1021/acscatal.0c01892 · 2020 · External reference
Engineering carboxylic acid reductase (CAR) through a whole-cell growth-coupled NADPH recycling strategy
10.1021/acssynbio.0c00290 · 2020 · External reference
Growth-based, high-throughput selection for NADH preference in an oxygen-dependent biocatalyst
10.1021/acssynbio.1c00258 · 2021 · External reference
Directed evolution of phosphite dehydrogenase to cycle noncanonical redox cofactors via universal growth selection platform
10.1038/s41467-022-32727-w · 2022 · External reference
An “energy-auxotroph” Escherichia coli provides an in vivo platform for assessing NADH regeneration systems
10.1002/bit.27490 · 2020 · External reference
NADPH-auxotrophic E. coli: A sensor strain for testing in vivo regeneration of NADPH
10.1021/acssynbio.8b00313 · 2018 · External reference
Expanding the scope of redox-balance growth coupling techniques with a carbon co-feeding strategy
10.1016/j.ymben.2026.05.004 · 2026 · External reference
Adaptive laboratory evolution recruits the promiscuity of succinate semialdehyde dehydrogenase to repair different metabolic deficiencies
10.1038/s41467-024-53156-x · 2024 · External reference
Stress-induced evolution of Escherichia coli points to original concepts in respiratory cofactor selectivity
10.1073/pnas.1010431108 · 2011 · External reference
A genetically encoded tool for manipulation of NADP+/NADPH in living cells
10.1038/nchembio.2454 · 2017 · External reference
Substrate-protein interactions of type II NADH:Quinone oxidoreductase from Escherichia coli
10.1021/acs.biochem.6b00070 · 2016 · External reference
Change in cofactor specificity of oxidoreductases by adaptive evolution of an Escherichia coli NADPH-auxotrophic strain
10.1128/mbio.00329-21 · 2021 · External reference
NADH inhibition and NAD activation of Escherichia coli lipoamide dehydrogenase catalyzing the NADH-lipoamide reaction
10.1016/s0021-9258(19)69779-6 · 1981 · External reference
Modification of substrate specificity in single point mutants of Agrobacterium tumefaciens type II NADH dehydrogenase
10.1016/j.febslet.2007.07.035 · 2007 · External reference
Metabolic engineering of an ATP-neutral Embden-Meyerhof-Parnas pathway in Corynebacterium glutamicum: growth restoration by an adaptive point mutation in NADH dehydrogenase
10.1128/aem.03116-14 · 2015 · External reference
The ldhA gene encoding the fermentative lactate dehydrogenase of Escherichia coli
10.1099/00221287-143-1-187 · 1997 · External reference
The crystal structure of D-lactate dehydrogenase, a peripheral membrane respiratory enzyme
10.1073/pnas.97.17.9413 · 2000 · External reference
Relevance of NADH dehydrogenase and alternative two-enzyme systems for growth of Corynebacterium glutamicum with glucose, lactate, and acetate
10.3389/fbioe.2020.621213 · 2020 · External reference
A review on comprehensive strategies for decarbonizing bioethanol production process
10.1016/j.gerr.2025.100153 · 2025 · External reference
Recent advances in lactic acid production by microbial fermentation processes
10.1016/j.biotechadv.2013.04.002 · 2013 · External reference
Lactic acid production by Lactobacillus casei using a sequence of seasonally available fruit wastes as sustainable carbon sources
10.3389/fbioe.2024.1447278 · 2024 · External reference
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
10.1073/pnas.120163297 · 2000 · External reference
AfterQC: automatic filtering, trimming, error removing and quality control for fastq data
10.1186/s12859-017-1469-3 · 2017 · External reference
Identification of mutations in laboratory-evolved microbes from next-generation sequencing data using breseq
10.1007/978-1-4939-0554-6_12 · 2014 · External reference
ALEdb 1.0: a database of mutations from adaptive laboratory evolution experimentation
10.1093/nar/gky983 · 2019 · External reference
10.17504/protocols.io.6qpvr6xjpvmk/v1
10.17504/protocols.io.6qpvr6xjpvmk/v1 · External reference
Fast growth and high-titer bioproduction from renewable formate via metal-dependent formate dehydrogenase in Escherichia coli
10.1038/s41467-025-61001-y · 2025 · External reference
10.17504/protocols.io.e6nvwk1z7vmk/v2
10.17504/protocols.io.e6nvwk1z7vmk/v2 · External reference
Critical assessment of proteome-wide label-free absolute abundance estimation strategies
10.1002/pmic.201300135 · 2013 · External reference
Absolute quantification of proteins by LCMSE
10.1074/mcp.m500230-mcp200 · 2006 · External reference
Boltz-2: Towards accurate and efficient binding affinity prediction
2025 · External reference
Boltz-1 democratizing biomolecular interaction modeling
2025 · External reference
Foldy: a web application for interactive protein structure analysis
2023 · External reference