Research graph
References from FDG-PET assessment of the locus coeruleus in Alzheimer’s disease. Local targets link to admitted publications; unresolved targets remain external evidence.
Diffusion tensor imaging in Alzheimer’s disease: insights into the limbic-diencephalic network and methodological considerations
10.3389/fnagi.2014.00266 · 2014 · External reference
Thalamic pathology and memory loss in early Alzheimer’s disease: moving the focus from the medial temporal lobe to Papez circuit
10.1093/brain/aww083 · 2016 · External reference
A reproducible evaluation of ANTs similarity metric performance in brain image registration
10.1016/j.neuroimage.2010.09.025 · 2011 · External reference
In vivo MRI assessment of the human locus coeruleus along its rostrocaudal extent in young and older adults
10.1016/j.neuroimage.2017.09.042 · 2017 · External reference
Locus coeruleus MRI contrast is reduced in Alzheimer’s disease dementia and correlates with CSF Aβ levels
2019 · External reference
Locus coeruleus imaging as a biomarker for noradrenergic dysfunction in neurodegenerative diseases
10.1093/brain/awz193 · 2019 · External reference
Stages of the pathologic process in Alzheimer disease: age categories from 1 to 100 years
10.1097/nen.0b013e318232a379 · 2011 · External reference
Regional brain glucose metabolism during morning and evening wakefulness in humans: preliminary findings
10.1093/sleep/27.7.1245 · 2004 · External reference
Neuromelanin marks the spot: identifying a locus coeruleus biomarker of cognitive reserve in healthy aging
10.1016/j.neurobiolaging.2015.09.019 · 2016 · External reference
Unresolved reference
2013 · External reference
The fornix and mammillary bodies in older adults with Alzheimer’s disease, mild cognitive impairment, and cognitive complaints: a volumetric MRI study
10.1016/j.pscychresns.2006.01.015 · 2006 · External reference
Rostral locus coeruleus integrity is associated with better memory performance in older adults
10.1038/s41562-019-0715-2 · 2019 · External reference
Comparison of positron emission tomography, cognition, and brain volume in Alzheimer’s disease with and without severe abnormalities of white matter
10.1136/jnnp.60.2.158 · 1996 · External reference
Neuropathologic correlates of psychiatric symptoms in Alzheimer’s disease
10.3233/jad-180688 · 2018 · External reference
The human locus coeruleus 3-D stereotactic anatomy
10.1007/s00276-012-0979-y · 2012 · External reference
Diurnal variation in regional brain glucose metabolism in depression
10.1016/j.biopsych.2006.09.043 · 2007 · External reference
Locus coeruleus neurofibrillary degeneration in aging, mild cognitive impairment and early Alzheimer’s disease
10.1016/j.neurobiolaging.2006.02.007 · 2007 · External reference
Cerebral glucose metabolism in preclinical and prodromal Alzheimer’s disease
10.1586/ern.10.136 · 2010 · External reference
Comparability of FDG PET studies in probable Alzheimer’s disease
1993 · External reference
Increased activity of surviving locus ceruleus neurons in Alzheimer’s disease
10.1002/1531-8249(199901)45:1<82::aid-art14>3.0.co;2-t · 1999 · External reference
NIA-AA Research Framework: toward a biological definition of Alzheimer’s disease
10.1016/j.jalz.2018.02.018 · 2018 · External reference
The Alzheimer’s disease neuroimaging initiative (ADNI): MRI methods
10.1002/jmri.21049 · 2008 · External reference
Review: does measurement of regional cerebral blood flow reflect synaptic activity? Implications for PET and fMRI
10.1006/nimg.1995.1017 · 1995 · External reference
Voxel-based mapping of brain gray matter volume and glucose metabolism profiles in normal aging
10.1016/j.neurobiolaging.2007.05.019 · 2009 · External reference
Locus coeruleus cellular and molecular pathology during the progression of Alzheimer’s disease
10.1186/s40478-017-0411-2 · 2017 · External reference
In vivo mapping of the human locus coeruleus
10.1016/j.neuroimage.2009.06.012 · 2009 · External reference
Histologic validation of locus coeruleus MRI contrast in post-mortem tissue
10.1016/j.neuroimage.2015.03.020 · 2015 · External reference
Reduced mammillary body volume in patients with obstructive sleep apnea
10.1016/j.neulet.2008.04.071 · 2008 · External reference
Region-specific hierarchy between atrophy, hypometabolism, and β-amyloid (Aβ) load in Alzheimer’s disease dementia
10.1523/jneurosci.2170-12.2012 · 2012 · External reference
In vivo visualization of age-related differences in the locus coeruleus
10.1016/j.neurobiolaging.2018.10.014 · 2018 · External reference
Magnetic resonance imaging of the human locus coeruleus: a systematic review
10.1016/j.neubiorev.2017.10.023 · 2017 · External reference
Locus coeruleus cell loss in the aging human brain: a non-random process
10.1002/cne.903580105 · 1995 · External reference
Lipoprotein pigments—their relationship to ageing in the human nervous SystemII. The melanin content of pigmented nerve cells
10.1093/brain/97.1.489 · 1974 · External reference
Regional hypometabolism in Alzheimer’s disease as measured by positron emission tomography after correction for effects of partial volume averaging
10.1212/wnl.47.2.454 · 1996 · External reference
Preserved pontine glucose metabolism in Alzheimer disease: a reference region for functional brain image (PET) analysis
10.1097/00004728-199507000-00006 · 1995 · External reference
Glucose metabolism in normal aging and Alzheimer’s disease: methodological and physiological considerations for PET studies
2013 · External reference
Pre-clinical detection of Alzheimer’s disease using FDG-PET, with or without amyloid imaging
10.3233/jad-2010-091504 · 2010 · External reference
Limbic hypometabolism in Alzheimer’s disease and mild cognitive impairment
10.1002/ana.10669 · 2003 · External reference
Profound degeneration of wake-promoting neurons in Alzheimer’s disease
10.1016/j.jalz.2019.06.3916 · 2019 · External reference
FDG-PET as an independent biomarker for Alzheimer’s biological diagnosis: a longitudinal study
10.1186/s13195-019-0512-1 · 2019 · External reference
Functional neuroanatomy of the noradrenergic locus coeruleus: its roles in the regulation of arousal and autonomic function part II: physiological and pharmacological manipulations and pathological alterations of locus coeruleus activity in humans
10.2174/157015908785777193 · 2008 · External reference
The locus coeruleus and noradrenergic modulation of cognition
10.1038/nrn2573 · 2009 · External reference
Hypometabolism of the posterior cingulate cortex is not restricted to Alzheimer’s disease
10.1016/j.nicl.2018.05.024 · 2018 · External reference
Age-related changes in locus ceruleus on neuromelanin magnetic resonance imaging at 3 Tesla
10.2463/mrms.5.197 · 2006 · External reference
Vascular dysfunction-The disregarded partner of Alzheimer’s disease
10.1016/j.jalz.2018.07.222 · 2019 · External reference
Detection of changes in the locus coeruleus in patients with mild cognitive impairment and Alzheimer’s disease: high-resolution fast spin-echo T1-weighted imaging
10.1111/ggi.12280 · 2015 · External reference
Locus coeruleus volume and cell population changes during Alzheimer’s disease progression: a stereological study in human postmortem brains with potential implication for early-stage biomarker discovery
10.1016/j.jalz.2016.06.2362 · 2017 · External reference
N4ITK: improved N3 bias correction
10.1109/tmi.2010.2046908 · 2010 · External reference
Neuronal loss is greater in the locus coeruleus than nucleus basalis and substantia nigra in Alzheimer and Parkinson diseases
10.1001/archneur.60.3.337 · 2003 · External reference