Research graph
References from Fatty acid amide hydrolase levels in brain linked with threat-related amygdala activation. Local targets link to admitted publications; unresolved targets remain external evidence.
Amygdalar lateralization in fear conditioning: evidence for greater involvement of the right amygdala
10.1037/0735-7044.118.1.15 · 2004 · External reference
The fatty acid amide hydrolase C385A variant affects brain binding of the positron emission tomography tracer [11C]CURB
10.1038/jcbfm.2015.119 · 2015 · External reference
Blocking of fatty acid amide hydrolase activity with PF-04457845 in human brain: a positron emission tomography study with the novel radioligand [11C]CURB
10.1038/jcbfm.2015.133 · 2015 · External reference
Fatty acid amide hydrolase binding in brain of cannabis users: imaging with the novel radiotracer [11C]CURB
10.1016/j.biopsych.2016.04.012 · 2016 · External reference
Unresolved reference
External reference
Effect of endocannabinoid degradation on pain: role of FAAH polymorphisms in experimental and postoperative pain in women treated for breast cancer
10.1097/j.pain.0000000000000398 · 2016 · External reference
The impact of T1 versus EPI spatial normalization templates for fMRI data analyses
10.1002/hbm.23737 · 2017 · External reference
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition
2011 · External reference
Afferent connections of the medial frontal cortex of the rat. II. Cortical and subcortical afferents
10.1002/cne.903520407 · 1995 · External reference
FAAH genetic variation enhances fronto-amygdala function in mouse and human
10.1038/ncomms7395 · 2015 · External reference
Acute stress increases circulating anandamide and other N-acylethanolamines in healthy humans
10.1038/npp.2012.100 · 2012 · External reference
Comparative analysis of fatty acid amide hydrolase and cb(1) cannabinoid receptor expression in the mouse brain: evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling
10.1016/s0306-4522(03)00145-3 · 2003 · External reference
Measuring facial movement
10.1007/bf01115465 · 1976 · External reference
What is the test-retest reliability of common task-functional MRI measures? New empirical evidence and a meta-analysis
10.1177/0956797620916786 · 2020 · External reference
Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces
10.1016/j.neuron.2004.12.006 · 2004 · External reference
Resting-state functional connectivity between amygdala and the ventromedial prefrontal cortex following fear reminder predicts fear extinction
10.1093/scan/nsw031 · 2016 · External reference
Unresolved reference
1997 · External reference
Impact of FAAH genetic variation on fronto-amygdala function during emotional processing
10.1007/s00406-018-0944-9 · 2019 · External reference
Individual differences in frontolimbic circuitry and Anxiety emerge with adolescent changes in endocannabinoid signaling across species
10.1073/pnas.1600013113 · 2016 · External reference
Spiral-in/out BOLD fMRI for increased SNR and reduced susceptibility artifacts
10.1002/mrm.1222 · 2001 · External reference
Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety
10.1523/jneurosci.2737-14.2015 · 2015 · External reference
Fatty acid amide hydrolase binding is inversely correlated with amygdalar functional connectivity: a combined positron emission tomography and magnetic resonance imaging study in healthy individuals
10.1503/jpn.200010 · 2021 · External reference
Amygdala FAAH and anandamide: mediating protection and recovery from stress
10.1016/j.tips.2013.08.008 · 2013 · External reference
Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity
10.1038/mp.2012.72 · 2013 · External reference
Microdeletion in a FAAH pseudogene identified in a patient with high anandamide concentrations and pain insensitivity
10.1016/j.bja.2019.02.019 · 2019 · External reference
The left amygdala knows fear: laterality in the amygdala response to fearful eyes
10.1093/scan/nsn001 · 2008 · External reference
Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function
10.1016/j.biopsych.2008.10.047 · 2009 · External reference
Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function
10.1016/j.biopsych.2008.10.047 · 2009 · External reference
Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic–pituitary–adrenal Axis
10.1038/npp.2009.114 · 2009 · External reference
Disruption of fatty acid amide hydrolase activity prevents the effects of chronic stress on anxiety and amygdalar microstructure
10.1038/mp.2012.90 · 2013 · External reference
Improved optimization for the robust and accurate linear registration and motion correction of brain images
10.1006/nimg.2002.1132 · 2002 · External reference
Coming to terms with fear
10.1073/pnas.1400335111 · 2014 · External reference
Long-term plasticity in amygdala circuits: implication of CB1-dependent LTD in stress
2018 · External reference
Cannabinoid CB1 receptors in the medial prefrontal cortex modulate the expression of contextual fear conditioning
10.1017/s1461145710000684 · 2010 · External reference
Age-related changes of anandamide metabolism in CB1 cannabinoid receptor knockout mice: correlation with behaviour
10.1046/j.1460-9568.2002.01957.x · 2002 · External reference
An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets
10.1016/s1053-8119(03)00169-1 · 2003 · External reference
Neural responses to facial expressions support the role of the amygdala in processing threat
10.1093/scan/nst162 · 2014 · External reference
Protective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice
2018 · External reference
Elevated anandamide, enhanced recall of fear extinction, and attenuated stress responses following inhibition of fatty acid amide hydrolase: a randomized, controlled experimental medicine trial
2019 · External reference
Targeting the endocannabinoid system in the treatment of PTSD: a promising case of preclinical-clinical translation?
2021 · External reference
Pre-training anandamide infusion within the basolateral amygdala impairs plus-maze discriminative avoidance task in rats
10.1016/j.nlm.2011.03.006 · 2011 · External reference
The endocannabinoid system as a target for novel anxiolytic drugs
10.1016/j.neubiorev.2016.12.033 · 2017 · External reference
The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial
2020 · External reference
Cannabinoid modulation of prefrontal-limbic activation during fear extinction learning and recall in humans
10.1016/j.nlm.2013.09.009 · 2014 · External reference
Neuroimaging studies of amygdala function in anxiety disorders
10.1111/j.1749-6632.2003.tb07096.x · 2003 · External reference
Estrogenic regulation of limbic cannabinoid receptor binding
10.1016/j.psyneuen.2010.02.008 · 2010 · External reference
The effect of CB(1) receptor antagonism in the right basolateral amygdala on conditioned fear and associated analgesia in rats
10.1111/j.1460-9568.2007.05861.x · 2007 · External reference
An automated method for the extraction of regional data from PET images
10.1016/j.pscychresns.2006.01.011 · 2006 · External reference
Mapping human brain fatty acid amide hydrolase activity with PET
10.1038/jcbfm.2012.180 · 2013 · External reference
Automatic denoising of functional MRI data: combining independent component analysis and hierarchical fusion of classifiers
10.1016/j.neuroimage.2013.11.046 · 2014 · External reference
The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study
10.1038/s41386-020-00888-1 · 2020 · External reference
The role of the amygdala in emotional processing: a quantitative meta-analysis of functional neuroimaging studies
10.1016/j.neubiorev.2007.12.002 · 2008 · External reference
A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder
10.1001/archpsyc.62.3.273 · 2005 · External reference
Fast robust automated brain extraction
10.1002/hbm.10062 · 2002 · External reference
Repeated fMRI in measuring the activation of the amygdala without habituation when viewing faces displaying negative emotions
10.1371/journal.pone.0198244 · 2018 · External reference
FAAH deficiency promotes energy storage and enhances the motivation for food
10.1038/ijo.2009.262 · 2010 · External reference
[11C]CURB: evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography
10.1016/j.nucmedbio.2010.08.001 · 2011 · External reference
Fatty acid amide hydrolase (FAAH) knockout mice exhibit enhanced acquisition of an aversive, but not of an appetitive, Barnes maze task
10.1016/j.nlm.2009.06.001 · 2009 · External reference