Research graph
References from Phase I and phase II enzyme activities in Ringed seals (Phoca hispida): characterization of hepatic cytochrome P450 by activity patterns, inhibition studies, mRNA analyses, and western blotting. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1007/978-3-642-69823-1_1
10.1007/978-3-642-69823-1_1 · External reference
Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9
10.3109/00498259509061850 · 1995 · External reference
Isolation and sequence determinations of a cDNA clone related to human cytochrome P450 nifedipine oxidase
10.1073/pnas.83.21.8064 · 1986 · External reference
Skull-bone lesions in the Baltic Grey seal (Halichoerus grypus)
1992 · External reference
Interspecies variation in caffeine metabolism related to cytochrome P4501A enzymes.Interspecies variation in caffeine metabolism related to cytochrome P4501A enzymes
10.3109/00498259209053129 · 1992 · External reference
10.1007/978-3-642-69823-1_3
10.1007/978-3-642-69823-1_3 · External reference
10.1016/b978-0-08-041874-2.50012-4
10.1016/b978-0-08-041874-2.50012-4 · External reference
Transthyretin (prealbumin) binding in PCBs, a model for the mechanism of interference with vitamin A and thyroid hormone metabolism
10.1016/0045-6535(86)90457-1 · 1986 · External reference
Poly-chloro-biphenyl contaminated fish induces vitamin A and thyroid hormone deficiency in the common seal (Phoca vitulina)
10.1016/0166-445x(89)90008-8 · 1989 · External reference
Unresolved reference
External reference
Ethoxyresorufin: direct fluorimetric assay of a microsomal O-dealkylation which is preferentially inducible by 3-methylcholanthrene
1974 · External reference
Cytochrome P450 specificities of alkoxyresorufin O-dealkylation in human and rat liver
10.1016/0006-2952(94)90363-8 · 1994 · External reference
Human cytochrome P450PA (P4501A2), the phenacetin O-deethylase is primarely responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines
10.1073/pnas.86.20.7696 · 1989 · External reference
Evaluation of triacetyloleandomycin, α-naphthoflavone, and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochrome P450
10.1006/abbi.1994.1259 · 1994 · External reference
10.1007/978-3-642-65177-9_25
10.1007/978-3-642-65177-9_25 · External reference
Cytochrome P450 in seals: monooxygenase activities, immunochemical cross-reactions and response to phenobarbital treatment
10.1016/0141-1136(92)90093-2 · 1992 · External reference
Development of human cytochrome P450-expressing cell lines: application in mutagenicity testing of ochratoxin A
1996 · External reference
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation
10.1016/s0021-9258(19)42083-8 · 1974 · External reference
Contemporary issues in toxicology. Selective inhibitors of cytochromes P450
10.1006/taap.1994.1061 · 1994 · External reference
Evidence for cytochrome P4501A and 2B forms in Fur seals (Callorhinus ursinus)
10.1016/0141-1136(96)87084-x · 1996 · External reference
Immunoquantitation and microsomal monooxygenase activities of hepatic cytochromes P4501A and P4502B and chlorinated hydrocarbon contaminant levels in Polar bear (Ursus maritimus)
10.1006/taap.1996.0065 · 1996 · External reference
Differential induction of rat liver microsomal UDP-glucuronosyltransferase activities by various inducing agents
10.1016/0006-2952(82)90319-7 · 1982 · External reference
Protein measurements with the Folin phenol reagents
10.1016/s0021-9258(19)52451-6 · 1951 · External reference
Organchlorine contaminants in arctic marine food chains: accumulation of specific PCBs and chlordane related compounds
10.1021/es00174a012 · 1988 · External reference
Chlorinated hydrocarbon contaminants in Arctic marine mammals
10.1016/0048-9697(94)90082-5 · 1994 · External reference
Indications of P450 monooxygenase activities in Beluga (Delphinapterus leucas) and Narwhal (Monodon monocerus) from patterns of PCB, PCDD and PCDF accumulation
10.1016/0141-1136(92)90119-7 · 1992 · External reference
10.1016/0048-9697(96)05082-6
10.1016/0048-9697(96)05082-6 · External reference
Enzyme induction in the cytochrome P450 enzyme system
10.1016/0163-7258(90)90030-6 · 1990 · External reference
Reproductive failure in Common seals feeding on fish from polluted coastal waters
10.1038/324456a0 · 1986 · External reference
Relative immunocompetence of the newborn Harbour seal (Phoca vitulina)
10.1016/0165-2427(94)90077-9 · 1994 · External reference
Interlaboratory comparison of total cytochrome P450 and protein determination in rat liver microsomes
10.1007/bf00324544 · 1987 · External reference
Seasonal changes in body mass and body composition in Ringed seals (Phoca hispida) on Svalbard
10.1139/z90-069 · 1990 · External reference
Polychlorinated biphenyls (PCBs): Environmental impact, biochemical and toxic responses, and implications for risk assessment
10.3109/10408449409049308 · 1994 · External reference
Furafylline is a potent and selective inhibitor of cytochrome P4501A2 in man
10.1111/j.1365-2125.1990.tb03686.x · 1990 · External reference
Short term fasting does not aggravate immunosuppression in harbour seal (Phoca vitulina) with high body burdens of organochlorines
10.1016/0045-6535(95)00298-m · 1995 · External reference
Direct characterization of the selectivity of furafylline as an inhibitor of human cytochrome P450 1A1 and 1A2
10.1097/00008571-199410000-00007 · 1994 · External reference
Catalytic and immunochemical characterization of hepatic microsomal cytochromes P450 in Beluga whales (Delphinapterus leucas)
10.1006/taap.1994.1089 · 1994 · External reference
Time-dependent induction of two distinct hepatic cytochrome P4501A catalytic activities at low temperatures in Arctic Char (Salvelinus alpinus) after oral exposure to benzo[a]pyrene
10.1016/0166-445x(96)00005-7 · 1996 · External reference
Regio and sterioselective metabolism of two C-19 steroids by five highly purified and reconstituted rat hepatic cytochrome P450 isoenzymes
10.1016/s0021-9258(18)32132-x · 1983 · External reference
The isoenzyme pattern of cytochrome P450 in rat hepatocytes in primary culture, comparing different enzyme activities in microsomal incubations and intact monolayers
10.1016/0006-2952(90)90095-3 · 1990 · External reference
Comparison of cytochrome P450 isoenzyme profiles in rat liver and hepatocyte cultures
10.1016/0006-2952(91)90726-l · 1991 · External reference
Acid reaction products of indole-3-carbinol and their effects on cytochrome P450 and phase II enzymes in rat and monkey hepatocytes
10.1016/0006-2952(92)90200-3 · 1992 · External reference
The effects of cooked brussels sprouts on cytochrome P450 profile and phase II enzymes in liver and small intestinal mucosa of the rat
10.1016/0278-6915(92)90132-5 · 1992 · External reference