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References from Application of Rat In Situ Single-pass Intestinal Perfusion in the Evaluation of Presystemic Extraction of Indinavir Under Different Perfusion Rates. Local targets link to admitted publications; unresolved targets remain external evidence.
Influence of the route of administration on the area under the plasma concentration-time curve
10.1002/jps.2600580114 · 1969 · External reference
Oral absorption and disposition kinetics of lidocaine hydrochloride in dogs
10.1016/s0022-3565(25)28585-8 · 1970 · External reference
Influence of first-pass effect on availability of drugs on oral administration
10.1002/jps.2600600909 · 1971 · External reference
Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction
10.1016/s0169-409x(97)00039-2 · 1997 · External reference
The mucosa of the small intestine: how clinically relevant as an organ of drug metabolism?
10.2165/00003088-200241040-00001 · 2002 · External reference
Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine
10.1016/0009-9236(95)90168-x · 1995 · External reference
Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism
10.1016/s0009-9236(96)90177-0 · 1996 · External reference
In vivo permeability studies in the gastrointestinal tract of humans
2003 · External reference
Absorption of drugs from the rat small intestine
10.1016/s0022-3565(25)12018-1 · 1958 · External reference
Intestinal drug absorption and metabolism I: comparison of methods and models to study physiological factors of in vitro and in vivo intestinal absorption
10.1002/jps.2600590204 · 1970 · External reference
Comparison of four experimental techniques for studying drug absorption kinetics in the anesthetized rat in situ
10.1002/jps.2600750203 · 1986 · External reference
Estimating human oral fraction dose absorbed: a correlation using rat intestinal membrane permeability for passive and carrier-mediated compounds
10.1023/a:1015927004752 · 1988 · External reference
A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability
10.1023/a:1016212804288 · 1995 · External reference
Effects of ethanol on pharma-cokinetics and intestinal absorption of paraquat in animals
10.2131/jts.19.2_67 · 1994 · External reference
The isolated perfused liver as a tool in drug metabolism studies
1999 · External reference
Simultaneous determination of the HIV-protease inhibitors indinavir, nelfinavie, saquinavir and ritonavir in human plasma by reversed-phase high-performance liquid chro-matography
10.1016/s0378-4347(99)00079-1 · 1999 · External reference
Simultaneous determinations of the HIV protease inhibitors indinavir, amprenavir, saquinavir, ritonavir and nelfinavir in human plasma by high-performance liquid chromatography
10.1016/s0378-4347(00)00617-4 · 2001 · External reference
Differential effects of hepatic microsomal enzyme inducing agents on liver blood flow
10.1016/0006-2952(78)90336-2 · 1978 · External reference
Species differences in the pharmacokinetics and metabolism of indinavir, a potent human immunodeficiency virus protease inhibitor
10.1016/s0090-9556(25)08414-4 · 1996 · External reference
Drug absorption I: an in situ rat gut technique yielding realistic absorption rates
10.1002/jps.2600581006 · 1969 · External reference
Reevaluation of the absorption of carbenoxolone using an in situ rat intestinal technique
10.1002/jps.2600790510 · 1990 · External reference
Evaluation of drug absorption and presystemic metabolism using an in situ intestinal preparation
10.1002/jps.2600750908 · 1986 · External reference
First-pass of GTS-21 on canine gut wall and liver determined by portal-systemic concentration difference
10.1016/s0928-0987(01)00166-x · 2001 · External reference
Effect of intestinal and hepatic metabolism on the bioavailability of tacrolimus in rats
10.1023/a:1011967519752 · 1998 · External reference
Cytochrome P450 and vascular homeostasis
10.1161/hh2101.099268 · 2002 · External reference
Expression of xenobiotic-metabolizing enzymes in human pulmonary tissue: possible role in susceptibility for ILD
10.1183/09031936.01.18s320122 · 2001 · External reference
Expression and regulation of xenobiotic-metabolizing cytochrome P450 (CYP) enzymes in human lung
10.1080/20024091064273 · 2002 · External reference
Factors affecting the clinical development of cytochrome P450 3A substrates
10.2165/00003088-200342110-00003 · 2003 · External reference
Hepatic and intestinal metabolism of indinavir, an HIV protease inhibitor, in rat and human microsomes. Major role of CYP3A
10.1016/s0006-2952(97)00100-7 · 1997 · External reference
Oral absorption of the HIV protease inhibitors: a current update
10.1016/s0169-409x(99)00027-7 · 1999 · External reference
L-735,524: an orally bioavailable human immunodeficiency virus type 1 protease inhibitor
10.1073/pnas.91.9.4096 · 1994 · External reference
pH-dependent oral absorption of L-735,524, a potent HIV protease inhibitor, in rats and dogs
10.1016/s0090-9556(25)06651-6 · 1995 · External reference
Pharmacoki-netic interactions between HIV-protease inhibitors in rats
10.1002/(sici)1099-081x(199907)20:5<241::aid-bdd182>3.0.co;2-u · 1999 · External reference
In-vitro and in-vivo pharmacokinetic interactions of amprenavir, an HIV protease inhibitor, with other current HIV protease inhibitors in rats
10.1211/0022357021778411 · 2002 · External reference
Optimal per-fusion rate determined for in situ intestinal absorption studies in rats
10.1002/jps.2600700303 · 1981 · External reference
Quantitative mechanistic studies in simultaneous fluid flow and intestinal absorption using steroids as model solutes
10.1016/0378-5173(80)90140-4 · 1980 · External reference
The liver as an organ
2006 · External reference
Comparison of intestinal permeabilities determined in multiple in vitro and in situ models: relationship to absorption in humans
10.1023/a:1016207525186 · 1995 · External reference
