Research graph
References from Inactivation of the p14ARF, p15INK4B and p16INK4A genes is a frequent event in human oral squamous cell carcinomas. Local targets link to admitted publications; unresolved targets remain external evidence.
The INK4a/ARF tumor suppressor
10.1016/s0968-0004(98)01236-5 · 1998 · External reference
G1 phase progression
10.1016/0092-8674(94)90540-1 · 1994 · External reference
Principles of CDK regulation
10.1038/374131a0 · 1995 · External reference
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
10.1016/s0092-8674(00)81400-2 · 1998 · External reference
Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
10.1016/s0092-8674(00)81902-9 · 1997 · External reference
p19ARF links the tumour suppressor p53 to Ras
10.1038/25870 · 1998 · External reference
p14ARF links the tumour suppressors RB and p53
10.1038/25867 · 1998 · External reference
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
10.1038/366704a0 · 1993 · External reference
p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest
10.1038/371257a0 · 1994 · External reference
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B
1996 · External reference
Allelotype of head and neck squamous cell carcinoma
1994 · External reference
The incidence of p53 mutations increases with progression of head and neck cancer
1993 · External reference
Loss of heterozygosity and mutation analysis of the p16(9p21) and p53(17p13) genes in squamous cell carcinoma of the head and neck
1994 · External reference
Frequent loss of chromosome 9p21-22 early in head and neck cancer progression
1994 · External reference
Cyclin-dependent kinase inhibitors and human cancer
19987 · External reference
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
10.1016/s0092-8674(00)80452-3 · 1997 · External reference
Genomic alterations of the p19ARF encoding exons in T-cell acute lymphoblastic leukemia
10.1182/blood.v91.3.1016 · 1998 · External reference
p16INK4a
1996 · External reference
Induction of Cip/Kip and Ink4 cyclin dependent kinase inhibitors by interferon-alpha in hematopoietic cell lines
10.1038/sj.onc.1200832 · 1997 · External reference
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma
1996 · External reference
Tumor suppressor gene p16 (CDKN2A) mutation status and promoter inactivation in head and neck cancer
41999 · External reference
Biologic and biochemical analyses of p16(INK4a) mutations from primary tumors
10.1093/jnci/91.18.1569 · 1999 · External reference
Differential expression of key cell cycle genes (p16/cyclinD1/pRb) in head and neck squamous cell carcinoma
1999 · External reference
Complex structure and regulation of the p16 (MTS1) locus
1995 · External reference