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References from New insights into p53 protein stabilisation in oral squamous cell carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Implications of the p53 tumour suppressor gene in clinical oncology
10.1200/jco.1995.13.4.1009 · 1995 · External reference
Expression of the tumour suppressor gene p53 in oral cancer
10.1016/0266-4356(92)90263-i · 1992 · External reference
Expression of p53 mutant nuclear phosphoprotein in oral carcinoma and potentially malignant oral lesions
10.1111/j.1600-0714.1992.tb01028.x · 1992 · External reference
Over-expression of p53 in head and neck cancer
10.1002/hed.2880140603 · 1992 · External reference
Assessment of p53 protein expression in normal, benign and malignant oral mucosa
10.1002/path.1711660411 · 1992 · External reference
Elevated p53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck
10.1038/bjc.1991.352 · 1991 · External reference
Sequential p53 mutation analysis of pre-invasive and invasive head and neck squamous carcinoma
10.1002/ijc.2910640309 · 1995 · External reference
High incidence of p53 alterations (mutation, deletion, overexpression) in head and neck primary tumours and metastases; absence of correlation with clinical outcome. Frequent protein overexpression in normal epithelium and in early non-invasive lesions
1995 · External reference
The incidence of p53 mutations increases with progression of head and neck cancer
1993 · External reference
Association between cigarette smoking and mutation of the p53 gene in squamous cell carcinoma of the head and neck
10.1056/nejm199503163321104 · 1995 · External reference
Occurrence of p53 gene deletions and human papilloma virus infection in human head and neck cancer
1992 · External reference
p53 mutations, protein expression and cell proliferation in squamous cell carcinomas of the head and neck
10.1038/bjc.1995.159 · 1995 · External reference
Clinical implications of the p53 tumour-suppressor gene
10.1056/nejm199310283291807 · 1993 · External reference
Loss of heterozygosity and p53 gene mutations in breast cancer
1994 · External reference
p53 allele losses, mutation and expression in breast cancer and their relationship to clinicopathological parameters
10.1002/ijc.2910500405 · 1992 · External reference
An uncertain role for p53 gene alterations in human prostate cancers
1996 · External reference
Altered p53 in microdissected, metachronous, premalignant and malignant oral lesions from the same patients
10.1136/mp.48.5.m269 · 1995 · External reference
Loss of 17p, mutation of the p53 gene and overexpression of p53 protein in oesophageal squamous cell carcinomas
1993 · External reference
Dominant-negative mutations in yeast hit cancer hot spots
10.1073/pnas.93.9.4091 · 1996 · External reference
Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumours
10.1016/0092-8674(93)90461-x · 1993 · External reference
Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas
1991 · External reference
Correlation between p53 mutations and antibody staining in breast carcinoma
10.1002/bjs.1800801118 · 1993 · External reference
p53 protein detected by immunohistochemical staining is not always mutant
10.1155/1993/480686 · 1993 · External reference
Genetic alterations of the TP53 gene, p53 protein expression and HPV infection in primary cervical carcinomas
10.1002/path.1711710207 · 1993 · External reference
The p53 and mdm-2 genes in human testicular germ cell tumours
10.1002/mc.2940120303 · 1995 · External reference
Frequently elevated content of immunochemically defined wild-type p53 protein in colorectal adenomas
1993 · External reference
A study of p53 protein versus point mutation in colorectal carcinoma
1994 · External reference
Comparison of p53 gene mutation and protein expression in colorectal carcinoma
10.1038/bjc.1994.355 · 1994 · External reference
Over-expression of p53 protein in squamous cell carcinoma of head and neck without apparent gene mutations
10.1097/00019606-199406000-00004 · 1994 · External reference
The regulation of p53 function: Steiner Award Lecture
10.1002/ijc.2910570502 · 1994 · External reference
p53 in tumour pathology: can we trust immunocytochemistry?
10.1002/path.1711660402 · 1992 · External reference
High levels of p53 protein in UV irradiated human skin
1993 · External reference
p53 immunostaining positivity is associated with reduced survival and is imperfectly correlated with gene mutations in resected non-small cell lung cancer
10.1378/chest.106.6.377s · 1994 · External reference
p53 protein stability in tumour cells is not determined by mutation but is dependent on mdm2 binding
10.1038/sj.onc.1201459 · 1997 · External reference
Two critical hydrophobic amino acids in the N-terminal domain of the p53 protein are required for the gain of function phenotypes of human p53 mutants
1995 · External reference
Mdm2 promotes the rapid degradation of p53
10.1038/387296a0 · 1997 · External reference
Regulation of p53 stability by mdm2
10.1038/387299a0 · 1997 · External reference
Amplification of a gene encoding a p53-associated protein in human sarcomas
10.1038/358080a0 · 1992 · External reference
The p53-mdm2 autoregulatory feedback loop
10.1101/gad.7.7a.1126 · 1993 · External reference
10.1016/s0968-0004(97)01119-5
10.1016/s0968-0004(97)01119-5 · External reference
Expression of TNF and the 55kDa TNF receptor in epidermis, oral mucosa, lichen planus and squamous cell carcinoma
10.1111/j.1601-0825.1996.tb00199.x · 1996 · External reference
LOH at 3p correlates with a poor survival in oral squamous cell carcinoma
10.1038/bjc.1996.62 · 1996 · External reference
Allelotype of colorectal carcinoma
10.1126/science.2565047 · 1989 · External reference
Expression of p53 in premalignant and malignant squamous epithelia
1991 · External reference
p53 mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features
1992 · External reference
Purification of mouse immunoglobulin heavy chain mRNA from total myeloma tumour RNA
10.1111/j.1432-1033.1980.tb06030.x · 1980 · External reference
Production of TGFα and TGFβ by cultured keratinocytes, skin and oral squamous cell carcinoma-potential autocrine regulation of normal and malignant epithelial cell proliferation
10.1038/bjc.1989.310 · 1989 · External reference
Primary structure polymorphism at amino acid residue 72 of human p53
10.1128/mcb.7.2.961 · 1987 · External reference
Number and evolutionary conservation of α and β tubulin and cytoplasmic β and γ actin genes using specific cloned cDNA probes
10.1016/0092-8674(80)90238-x · 1980 · External reference
Loss of heterozygosity studies on chromosome 17 in head and neck cancer using microsatellite markers
1994 · External reference
Loss of heterozygosity of p53 in oral cancers demonstrated by the polymerase chain reaction
10.1002/1097-0142(19930315)71:6<1933::aid-cncr2820710602>3.0.co;2-d · 1993 · External reference
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3
10.1038/nm0695-570 · 1995 · External reference
Improved detection of p53 point mutations by dideoxyfingerprinting (ddF)
1996 · External reference
Mutations in the p53 tumour suppressor gene: Clues to cancer etiology and molecular pathogenesis
1994 · External reference
Inactivation of the p53 gene by either mutation or HPV infection is extremely frequent in human oral squamous cell carcinoma cell lines
10.1016/0964-1955(94)90036-1 · 1994 · External reference
p53 gene mutation and HPV and neck squamous cell carcinomas do not correlate with overall survival: a long term follow-up study
10.1111/j.1600-0714.1997.tb00222.x · 1997 · External reference
High frequency of p53 gene alterations associated with protein over-expression in human squamous cell carcinoma of the larynx
1992 · External reference
MDM2 protein is expressed in different layers of normal human skin
10.1038/sj.onc.1200922 · 1997 · External reference
DNA damage increases the levels of MDM2 messenger RNA in wtp53 human cells
1994 · External reference
Epithelial ovarian cancer: influence of polymorphism to the glutathione S-transferase GSTM1 and GST1 loci on p53 expression
10.1038/bjc.1996.626 · 1996 · External reference
Apoptosis in normal epithelium, premalignant and malignant lesions of the oropharynx and oral cavity: a preliminary study
10.1016/0964-1955(95)00048-8 · 1995 · External reference
p53 mutations in squamous cell carcinoma of the head and neck predominate in a subgroup of former and present smokers with a low frequency of genetic instability
1997 · External reference
Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers
10.1016/s0092-8674(00)80540-1 · 1997 · External reference
A novel protein with strong homology to the tumour suppressor p53
10.1038/sj.onc.1201500 · 1997 · External reference
