References

A cell cycle regulator potentially involved in genesis of many tumor types

10.1126/science.8153634 · 1994 · External reference

Germline p16 mutations in familial melanoma

10.1038/ng0994-15 · 1994 · External reference

Deletion of p16 and p15 genes in brain tumors

1994 · External reference

CDKN2 (MTS1) tumor suppressor gene mutations in human tumor cell lines

1995 · External reference

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

10.1038/ng1095-210 · 1995 · External reference

Role of the p16 tumor suppressor gene in cancer

10.1200/jco.1998.16.3.1197 · 1998 · External reference

Estimates of the worldwide incidence of eighteen major cancer in 1985

10.1002/ijc.2910540413 · 1993 · External reference

Allelotype of head and neck squamous cell carcinoma

1994 · External reference

Allelotype of squamous cell carcinoma of the head and neck: fractional allele loss correlates with survival

10.1038/bjc.1995.483 · 1995 · External reference

Genetic progression model for head and neck cancer: implications for field cancerization

1996 · External reference

Suppression of tumorigenicity in three different cell lines of human oral squamous cell carcinoma by introduction of chromosome 3p via microcell-mediated chromosome transfer

1995 · External reference

Frequent loss of chromosome 9p21-22 early in head and neck cancer progression

1994 · External reference

Frequent microsatellite alterations at chromosomes 9p21 and 3p14 in oral premalignant lesions and their value in cancer risk assessment

10.1038/nm0696-682 · 1996 · External reference

Distinct patterns of chromosomal alterations in high- and low-grade head and neck squamous cell carcinomas

1996 · External reference

p16MTS1/CDK4I mutations and concomitant loss of heterozygosity at 9p21-23 are frequent events in squamous cell carcinoma of larynx

10.1038/sj.onc.1201309 · 1997 · External reference

Higher frequency of alterations in the p16/CDKN2 gene in squamous cell carcinoma cell lines than in primary tumors of the head and neck

1994 · External reference

Homozygous deletions and loss of expression of the CDKN2 gene occur frequently in head and neck squamous cell carcinoma cell lines but infrequently in primary tumors

10.1002/gcc.2870130204 · 1995 · External reference

Mutational state of p16/CDKN2 and VHL genes in squamous-cell carcinoma of the oral cavity

1995 · External reference

High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma

1996 · External reference

Complex structure and regulation of the p16 (MTS1) locus

1995 · External reference

A novel p16INK4a transcript

1995 · External reference

The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53

10.1016/s0092-8674(00)81400-2 · 1998 · External reference

ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways

10.1016/s0092-8674(00)81401-4 · 1998 · External reference

Multiple type of aberrations in the p16 (INK4a) and the p15 (INK4b) genes in 30 esophageal squamous-cell-carcinoma cell lines

10.1002/(sici)1097-0215(19970207)70:4<437::aid-ijc11>3.0.co;2-c · 1997 · External reference

CDKN2A/p16 is inactivated in most melanoma cell lines

1997 · External reference

Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers

1995 · External reference

Methylation of the 5′ CpG island of the p16/CDKN2 tumor suppressor gene in normal and transformed human tissues correlates with gene silencing

1995 · External reference

p16 gene in uncultured tumors

10.1038/370183a0 · 1994 · External reference

Frequent inactivation of p16INK4a in oral premalignant lesions

10.1038/sj.onc.1201010 · 1997 · External reference