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References from Impact of aging on DNA methylation. Local targets link to admitted publications; unresolved targets remain external evidence.
Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
10.1016/s1074-7613(00)80642-1 · 1998 · External reference
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
10.1038/13810 · 1999 · External reference
Number of CpG islands and genes in human and mouse
10.1073/pnas.90.24.11995 · 1993 · External reference
10.1007/978-3-0348-9118-9_8
10.1007/978-3-0348-9118-9_8 · External reference
Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin
10.1074/jbc.m104661200 · 2001 · External reference
Epigenetic regulation of an IAP retrotransposon in the aging mouse: progressive demethylation and de-silencing of the element by its repetitive induction
10.1093/nar/30.11.2365 · 2002 · External reference
Mechanisms underlying epigenetically mediated gene silencing in cancer
10.1016/s1044-579x(02)00053-6 · 2002 · External reference
Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxyl-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases
10.1016/0022-2836(88)90122-2 · 1988 · External reference
A mammalian protein with specific demethylase activity for mCpG DNA
10.1038/17533 · 1999 · External reference
The essentials of DNA methylation
10.1016/0092-8674(92)90526-i · 1992 · External reference
Gene number, noise reduction and biological complexity
10.1016/s0168-9525(00)89009-5 · 1995 · External reference
Methylation-induced repression—belts, braces, and chromatin
10.1016/s0092-8674(00)81532-9 · 1999 · External reference
CpG island methylation in aberrant crypt foci of the colorectum
10.1016/s0002-9440(10)61128-5 · 2002 · External reference
DNA hypomethylation leads to elevated mutation rates
10.1038/25779 · 1998 · External reference
High sensitivity mapping of methylated cytosines
10.1093/nar/22.15.2990 · 1994 · External reference
CpG methylation inhibits proenkephalin gene expression and binding of the transcription factor AP-2
10.1093/nar/18.13.3975 · 1990 · External reference
Dietary selenium and arsenic affect DNA methylation
10.1093/jn/131.6.1871 · 2001 · External reference
Hydralazine and procainamide inhibit T cell DNA methylation and induce autoreactivity
10.4049/jimmunol.140.7.2197 · 1988 · External reference
Cell proliferation and global methylation status changes in mouse liver after phenobarbital and/or choline-devoid, methionine-deficient diet administration
10.1093/carcin/17.6.1251 · 1996 · External reference
Role of the Ras-MAPK signaling pathway in the DNA methyltransferase response to DNA hypomethylation
10.1515/bchm.1998.379.8-9.1113 · 1998 · External reference
Decreased Ras-mitogen-activated protein kinase signaling may cause DNA hypomethylation in T lymphocytes from lupus patients
10.1002/1529-0131(200102)44:2<397::aid-anr59>3.0.co;2-n · 2001 · External reference
Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson’s disease
10.1046/j.0022-3042.2001.00676.x · 2002 · External reference
DNA methylation in cancer: too much, but also too little
10.1038/sj.onc.1205651 · 2002 · External reference
DNA methylation, genomic imprinting and cancer
2000 · External reference
DNA methylation and genomic imprinting: insights from cancer into epigenetic mechanisms
10.1016/s1044-579x(02)00059-7 · 2002 · External reference
Imprinting and the epigenetic asymmetry between parental genomes
10.1126/science.1064020 · 2001 · External reference
Quantitative changes in T cell DNA methylation occur during differentiation and ageing
10.1002/eji.1830200836 · 1990 · External reference
The DNMT3B DNA methyltransferase gene is mutated in the ICF immunodeficiency syndrome
10.1073/pnas.96.25.14412 · 1999 · External reference
A genomic scanning method for higher organisms using restriction sites as landmarks
10.1073/pnas.88.21.9523 · 1991 · External reference
The thymine glycosylase MBD4 can bind to the product of deamination at methylated CpG sites
10.1038/45843 · 1999 · External reference
CpG-island methylation in aging and cancer
2000 · External reference
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon
10.1038/ng0894-536 · 1994 · External reference
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis
10.1073/pnas.93.21.11757 · 1996 · External reference
Altering gene expression with 5-azacytidine
10.1016/0092-8674(85)90192-8 · 1985 · External reference
The role of DNA methylation in mammalian epigenetics
10.1126/science.1063852 · 2001 · External reference
A chicken embryo protein related to the mammalian DEAD box protein p68 is tightly associated with the highly purified protein-RNA complex of 5-MeC-DNA glycosylase
10.1093/nar/27.16.3245 · 1999 · External reference
Correspondence of RLGS-M spot behavior with tissue expression on mouse homologue of DP1/TB2 gene
10.1006/bbrc.1995.2223 · 1995 · External reference
DNA methylation, heterochromatin and epigenetic carcinogens
10.1016/s1383-5742(96)00052-x · 1997 · External reference
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer’s disease
10.1523/jneurosci.22-05-01752.2002 · 2002 · External reference
10.1093/hmg/3.suppl_1.1487
10.1093/hmg/3.suppl_1.1487 · External reference
DNA methylation and genetic instability in colorectal cancer cells
10.1073/pnas.94.6.2545 · 1997 · External reference
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
10.1016/0092-8674(92)90611-f · 1992 · External reference
Use of restriction enzymes to detect potential gene sequences in mammalian DNA
10.1038/327336a0 · 1987 · External reference
Differential maintenance and de novo methylating activity by three DNA methyltransferases in aging and immortalized fibroblasts
10.1002/jcb.10015 · 2002 · External reference
Demethylation of ITGAL (CD11a) regulatory sequences in systemic lupus erythematosus
10.1002/art.10234 · 2002 · External reference
Effect of DNA methylation and chromatin structure on ITGAL expression
10.1182/blood.v99.12.4503 · 2002 · External reference
Regulation of DNA methylation by the Ras signaling pathway
10.1074/jbc.270.19.11327 · 1995 · External reference
Beckwith-Wiedemann syndrome: imprinting in clusters revisited
10.1172/jci9340 · 2000 · External reference
Host defenses to parasitic sequences and the evolution of epigenetic control mechanisms
10.1023/a:1003921710672 · 1999 · External reference
Decreased methylation of the major mouse long interspersed repeated DNA during aging and in myeloma cells
10.1002/dvg.1020070202 · 1986 · External reference
Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
10.1038/30764 · 1998 · External reference
Variable effects of DNA-synthesis inhibitors upon DNA methylation in mammalian cells
10.1093/nar/14.10.4353 · 1986 · External reference
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
10.1038/890 · 1998 · External reference
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
10.1016/s0092-8674(00)81656-6 · 1999 · External reference
Endogenous virus genomes become hypomethylated tissue—specifically during aging process of C57BL mice
10.1016/0047-6374(89)90056-0 · 1989 · External reference
Biological significance of DNA methylation in the ageing process
10.1093/ageing/22.suppl_1.s34 · 1993 · External reference
Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells
1994 · External reference
Quantitative analysis of lymphocyte CD11a using standardized flow cytometry
10.1111/j.1365-3083.1993.tb03241.x · 1993 · External reference
Age-dependent changes of p57(Kip2) and p21(Cip1/Waf1) expression in skeletal muscle and lung of mice
10.1016/s0167-4781(01)00266-4 · 2001 · External reference
Epigenetic aspects of X-chromosome dosage compensation
10.1126/science.1063073 · 2001 · External reference
The effects of diet, genetics and chemicals on toxicity and aberrant DNA methylation: an introduction
10.1093/jn/132.8.2336s · 2002 · External reference
Methylation of repetitive DNA sequences in the brain during aging of the rat
10.1016/0014-5793(89)81191-3 · 1989 · External reference
Epigenetic reprogramming in mammalian development
10.1126/science.1063443 · 2001 · External reference
Role of DNA methylation in the regulation of cell function: autoimmunity, aging and cancer
10.1093/jn/132.8.2401s · 2002 · External reference
Evidence for impaired T cell DNA methylation in systemic lupus erythematosus and rheumatoid arthritis
10.1002/art.1780331109 · 1990 · External reference
Lymphocyte function-associated antigen 1 overexpression and T cell autoreactivity
10.1002/art.1780370915 · 1994 · External reference
Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction
10.1016/0005-2787(81)90156-8 · 1981 · External reference
Regulation of the DNA methyltransferase by the Ras-AP-1 signaling pathway
10.1074/jbc.270.4.1595 · 1995 · External reference
Vitamin A and its derivatives induce hepatic glycine N-methyltransferase and hypomethylation of DNA in rats
10.1093/jn/132.3.365 · 2002 · External reference
Cellular senescence: mitotic clock or culture shock?
10.1016/s0092-8674(00)00046-5 · 2000 · External reference
Messenger RNA levels and methylation patterns of GAPDH and beta-actin genes in rat liver, spleen and brain in relation to aging
10.1016/0047-6374(90)90042-e · 1990 · External reference
An increasingly complex code
10.1172/jci0216547 · 2002 · External reference
Age-dependent alterations in mRNA level and promoter methylation of collagen alpha1(I) gene in human periodontal ligament
10.1016/s0047-6374(99)00041-x · 1999 · External reference
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
10.1038/35065638 · 2001 · External reference
CpG island methylator phenotype in colorectal cancer
10.1073/pnas.96.15.8681 · 1999 · External reference
Infrequent occurrence of age-dependent changes in CpG island methylation as detected by restriction landmark genome scanning
10.1016/s0047-6374(02)00080-5 · 2002 · External reference
Rare bases in animal DNA
10.1038/225948a0 · 1970 · External reference
The 5-methylcytosine in DNA of rats. Tissue and age specificity and the changes induced by hydrocortisone and other agents
10.1159/000211967 · 1973 · External reference
Identification of a gene (FMR-1) containing a CGG repeat coincident with a breakpoint cluster region exhibiting length variation in Fragile X syndrome
10.1016/0092-8674(91)90397-h · 1991 · External reference
Mi-2 complex couples DNA methylation to chromatin remodelling and histone deacetylation
10.1038/12664 · 1999 · External reference
Genomic 5-methyldeoxycytidine decreases with age
10.1016/s0021-9258(18)61057-9 · 1987 · External reference
DNA demethylation
10.1073/pnas.96.11.5894 · 1999 · External reference
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells
10.1073/pnas.90.19.8891 · 1993 · External reference
Cytosine methylation and the ecology of intragenomic parasites
10.1016/s0168-9525(97)01181-5 · 1997 · External reference
Mechanism of drug-induced lupus. I. Cloned Th2 cells modified with DNA methylation inhibitors in vitro cause autoimmunity in vivo
10.4049/jimmunol.154.6.3025 · 1995 · External reference
Mechanisms of drug-induced lupus. II. T cells overexpressing lymphocyte function-associated antigen 1 become autoreactive and cause a lupus-like disease in syngeneic mice
10.1172/jci118743 · 1996 · External reference
Mechanisms of drug-induced lupus. IV. Comparison of procainamide and hydralazine with analogs in vitro and in vivo
10.1002/art.1780400811 · 1997 · External reference
Unexpected effects of a heterozygous dnmt1 null mutation on age-dependent DNA hypomethylation and autoimmunity
10.1093/gerona/56.6.b268 · 2001 · External reference
Age-dependent DNA methylation changes in the ITGAL (CD11a) promoter
10.1016/s0047-6374(02)00014-3 · 2002 · External reference