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References from Aging as war between chemical and biochemical processes: Protein methylation and the recognition of age-damaged proteins for repair. Local targets link to admitted publications; unresolved targets remain external evidence.
Stoichiometric methylation of porcine adrenocorticotropin by protein carboxyl methyltransferase requires deamidation of asparagine 25. Evidence for methylation at the α-carboxyl group of atypical l-isoaspartyl residues
10.1016/s0021-9258(18)90570-3 · 1984 · External reference
Isoaspartate in peptides and proteins: formation, significance, and analysis
10.1016/s0731-7085(99)00230-7 · 2000 · External reference
The influence of protein structure on the products emerging from succinimide hydrolysis
10.1074/jbc.m205314200 · 2002 · External reference
S-Adenosyl-l-methionine (SAMe): from the bench to the bedside—molecular basis of a pleiotrophic molecule
10.1093/ajcn/76.5.1151s · 2002 · External reference
Isoaspartyl bond formation within N-terminal sequences of collagen type I: implications for their use as markers of collagen degradation
10.1042/cs19980202 · 1999 · External reference
10.1002/chin.199532300
10.1002/chin.199532300 · External reference
Repair of spontaneously deamidated HPr phosphocarrier protein catalyzed by the l-isoaspartate-(d-aspartate) O-methyltransferase
10.1016/s0021-9258(17)31432-1 · 1994 · External reference
Ubiquitin-mediated proteolysis in learning and memory
10.1007/bf02742438 · 1999 · External reference
Extension of the Drosophila lifespan by overexpression of a protein repair methyltransferase
10.1073/pnas.251446498 · 2001 · External reference
Deamidation of asparagine in a major histocompatibility complex-bound peptide affects T cell recognition but does not explain type B reactivity
10.1084/jem.194.8.1165 · 2001 · External reference
Propensity for spontaneous succinimide formation from aspartyl and asparaginyl residues in cellular proteins
10.1111/j.1399-3011.1987.tb03390.x · 1987 · External reference
10.1142/9789812813077_0005
10.1142/9789812813077_0005 · External reference
10.1007/978-1-4615-0945-5_94
10.1007/978-1-4615-0945-5_94 · External reference
UVA irradiation induces l-isoaspartyl formation in melanoma cell proteins
10.1016/s0891-5849(01)00518-4 · 2001 · External reference
Human erythrocyte protein l-isoaspartyl methyltransferase: heritability of basal activity and genetic polymorphism for thermal stability
1997 · External reference
Isoaspartate in chrondroitin sulfate proteoglycans of mammalian brain
10.1074/jbc.273.48.32063 · 1998 · External reference
Isoaspartate in ribosomal protein S11 of Escherichia coli
10.1128/jb.181.9.2872-2877.1999 · 1999 · External reference
Polymorphic forms of the protein l-isoaspartate (d-aspartate) O-methyltransferase involved in the repair of age-damaged proteins
10.1007/s100380050161 · 1999 · External reference
Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of l-isoaspartyl (d-aspartyl) O-methyltransferase-deficient mice
10.1074/jbc.m203911200 · 2002 · External reference
Simultaneous stereoinversion and isomerization at specific aspartic acid residues in αA-crystallin from human lens
10.1093/oxfordjournals.jbchem.a124577 · 1994 · External reference
The presence of d-β-aspartic acid-containing peptides in elastic fibers of sun-damaged skin: a potent marker for ultraviolet-induced skin aging
10.1016/s0006-291x(02)00597-1 · 2002 · External reference
Synthesis, aggregation, and neurotoxicity of the Alzheimer’s Aβ1-42 amyloid peptide and its isoaspartyl isomers
10.1016/s0960-894x(99)00121-3 · 1999 · External reference
Protein damage and methylation-mediated repair in the erythrocyte
10.1042/bj3060313 · 1995 · External reference
Deamidation, isomerization
10.1016/s0021-9258(19)75855-4 · 1987 · External reference
Folate status and age affect the accumulation of l-isoaspartyl residues in rat liver proteins
10.1093/jn/132.6.1357 · 2002 · External reference
Unresolved reference
External reference
Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its l-isoaspartyl peptide substrate
10.1006/jmbi.2001.5095 · 2001 · External reference
Repair of oxidized proteins: identification of a new methionine sulfoxide reductase
10.1074/jbc.m105509200 · 2001 · External reference
Protein isoaspartyl methyltransferase protects from Bax-induced apoptosis
10.1016/s0378-1119(99)00443-6 · 1999 · External reference
A highly active protein repair enzyme from an extreme thermophile: the l-isoaspartyl methyltransferase from Thermotoga maritima
10.1006/abbi.1998.0830 · 1998 · External reference
Aberrant synaptic transmission in the hippocampal CA3 region and cognitive deterioration in protein-repair enzyme-deficient mice
10.1002/hipo.1043 · 2001 · External reference
Increased membrane-protein methylation in hereditary spherocytosis. A marker of cytoskeletal disarray
10.1111/j.1432-1033.1995.tb20337.x · 1995 · External reference
Increased methylesterification of altered aspartyl residues in erythrocyte membrane proteins in response to oxidative stress
10.1046/j.1432-1327.2000.01485.x · 2000 · External reference
Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deficient erythrocytes: role of oxidative stress
10.1046/j.1432-1033.2002.02838.x · 2002 · External reference
Protein carboxyl methyltransferase facilitates conversion of atypical l-isoaspartyl peptides to normal l-aspartyl peptides
10.1016/s0021-9258(18)45619-0 · 1987 · External reference
Partial repair of deamidation-damaged calmodulin by protein carboxyl methyltransferase
10.1016/s0021-9258(18)45348-3 · 1987 · External reference
Comparing mutants, selective breeding, and transgenics in the dissection of aging processes of Caenorhabditis elegans
10.1007/bf01435988 · 1993 · External reference
Molecular phylogenetics of a protein repair methyltransferase
10.1016/s0305-0491(96)00333-1 · 1997 · External reference
Targeted gene disruption of the Caenorhabditis elegans l-isoaspartyl protein repair methyltransferase impairs survival of dauer stage nematodes
10.1006/abbi.1997.0362 · 1997 · External reference
Deficiency of a protein-repair enzyme results in the accumulation of altered proteins, retardation of growth, and fatal seizures in mice
10.1073/pnas.94.12.6132 · 1997 · External reference
Phenotypic analysis of seizure-prone mice lacking l-isoaspartate (d-aspartate) O-methyltransferase
10.1074/jbc.274.29.20671 · 1999 · External reference
Folic acid deficiency and homocysteine impair DNA repair in hippocampal neurons and sensitize them to amyloid toxicity in experimental models of Alzheimer’s disease
10.1523/jneurosci.22-05-01752.2002 · 2002 · External reference
Age-induced protein modifications and increased proteolysis in potato-seed tubers
10.1104/pp.119.1.89 · 1999 · External reference
Methylation of atypical protein aspartyl residues during the stress response of HeLa cells
10.1002/jcp.1041530209 · 1992 · External reference
Down-regulation of protein l-isoaspartyl methyltransferase in human epileptic hippocampus contributes to generation of damaged tubulin
10.1046/j.1471-4159.2002.01150.x · 2002 · External reference
Age-dependent deamidation of asparagine residues in proteins
10.1016/s0531-5565(01)00140-1 · 2001 · External reference
Determination of two sites of automethylation in bovine erythrocyte protein (d-aspartyl/l-isoaspartyl) carboxyl methyltransferase
10.1007/bf01886817 · 1996 · External reference
10.1016/s0021-9258(18)55010-9
10.1016/s0021-9258(18)55010-9 · External reference
Recognition of d-aspartyl residues in polypeptides by the erythrocyte l-isoaspartyl/d-aspartyl protein methyltransferase. Implications for the repair hypothesis
10.1016/s0021-9258(18)42652-x · 1992 · External reference
Limited accumulation of damaged proteins in l-isoaspartyl (d-aspartyl) O-methyltransferase-deficient mice
10.1074/jbc.m100987200 · 2001 · External reference
Alternative splicing of the human isoaspartyl protein carboxyl methyltransferase RNA leads to the generation of a C-terminal-RDEL sequence in isozyme II
10.1016/s0006-291x(05)80987-8 · 1992 · External reference
Isoaspartyl post-translational modification triggers autoimmune responses to self-proteins
10.1074/jbc.274.32.22321 · 1999 · External reference
10.1073/pnas.79.8.2460
10.1073/pnas.79.8.2460 · External reference
Conversion of isoaspartyl peptides to normal peptides: implications for the cellular repair of damaged proteins
10.1073/pnas.84.9.2595 · 1987 · External reference
The fidelity of protein synthesis: can mischarging by aspartyl-tRNA(Asp) synthetase lead to the formation of isoaspartyl residues in proteins
10.1016/0167-4838(90)90070-v · 1990 · External reference
Protein repair l-isoaspartyl methyltransferase in plants. Phylogenetic distribution and the accumulation of substrate proteins in aged barley seeds
10.1104/pp.115.4.1481 · 1997 · External reference
Synthetic peptide substrates for the erythrocyte protein carboxyl methyltransferase. Detection of a new site of methylation at isomerized l-aspartyl residues
10.1016/s0021-9258(18)90571-5 · 1984 · External reference
Molecular aging of tubulin: accumulation of isoaspartyl sites in vitro and in vivo
10.1021/bi953063g · 1996 · External reference
Do damaged proteins accumulate in Caenorhabditis elegans l-isoaspartate methyltransferase (pcm1) deletion mutants
10.1006/abbi.1999.1114 · 1999 · External reference
Complex interactions of the protein l-isoaspartyl methyltransferase and calmodulin revealed with the yeast two-hybrid system
10.1074/jbc.273.21.12909 · 1998 · External reference
Spontaneous alterations in the covalent structure of synapsin I during in vitro aging
10.1006/bbrc.1995.1989 · 1995 · External reference
d-aspartate content of erythrocyte membrane proteins is decreased in uremia: implications for the repair of damaged proteins
10.1681/asn.v8195 · 1997 · External reference
The type II isoform of bovine brain protein l-isoaspartyl methyltransferase has an endoplasmic reticulum retention signal (RDEL) at its C-terminus
10.1021/bi00142a025 · 1992 · External reference
Accelerated racemization of aspartic acid and asparagine residues via succinimide intermediates: an ab initio theoretical exploration of mechanism
10.1021/ja953505b · 1996 · External reference
Neighboring side chain effects on asparaginyl and aspartyl degradation: an ab initio study of the relationship between peptide conformation and backbone NH acidity
10.1021/ja0026814 · 2001 · External reference
Protein deamidation
10.1073/pnas.082102799 · 2002 · External reference
Molecular clocks
10.1073/pnas.98.3.944 · 2001 · External reference
High-quality life extension by the enzyme peptide methionine sulfoxide reductase
10.1073/pnas.032671199 · 2002 · External reference
Crystal structure of human l-isoaspartyl methyltransferase
10.1074/jbc.m200229200 · 2002 · External reference
Spontaneous deamidation and isomerization of Asn108 in prion peptide 106–126 and in full-length prion protein
10.1006/bbrc.1999.1056 · 1999 · External reference
Enzymes that catalyze the restructuring of proteins
10.1016/s0959-440x(99)00046-9 · 2000 · External reference
Exceptional seed longevity and robust growth: ancient sacred lotus from China
10.2307/2445863 · 1995 · External reference
Isoaspartate formation and neurodegeneration in Alzheimer’s disease
10.1006/abbi.2000.1955 · 2000 · External reference
Isoaspartate formation at position 23 of amyloid β-peptide enhanced fibril formation and deposited onto senile plaques and vascular amyloids in Alzheimer’s disease
10.1002/jnr.10350 · 2002 · External reference
Crystal structure of a protein isoaspartyl methyltransferase: a catalyst for protein repair
10.1016/s0969-2126(00)00522-0 · 2000 · External reference
Crystal structure of human l-isoaspartyl-O-methyltransferase with S-adenosylhomocysteine at 1.6-Å resolution and modeling of an isoaspartyl-containing peptide at the active site
10.1110/ps.37802 · 2002 · External reference
Succinimide formation from aspartyl and asparaginyl peptides as a model for the spontaneous degradation of proteins
10.1016/s0021-9258(18)83327-0 · 1989 · External reference
Specific glutamine and asparagine residues of γ-S-crystallin are resistant to in vivo deamidation
10.1074/jbc.m002809200 · 2000 · External reference
Ca2+-free calmodulin and calmodulin damaged by in vitro aging are selectively degraded by 26S proteasomes without ubiquitination
10.1074/jbc.m001555200 · 2000 · External reference
Distinct patterns of expression but similar biochemical properties of protein l-isoaspartyl methyltransferase in higher plants
10.1104/pp.125.2.1023 · 2001 · External reference
Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus: unusual methyl-accepting affinity for d-aspartyl and N-succinyl-containing peptides
10.1074/jbc.m108261200 · 2002 · External reference
Repair, refold, recycle: how bacteria can deal with spontaneous and environmental damage to proteins
10.1111/j.1365-2958.1995.tb02311.x · 1995 · External reference
The l-isoaspartyl protein repair methyltransferase enhances survival of aging Escherichia coli subjected to secondary environmental stresses
10.1128/jb.180.10.2623-2629.1998 · 1998 · External reference
Mutations in the Escherichia coli surE gene increase isoaspartyl accumulation in a strain lacking the pcm repair methyltransferase but suppress stress-survival phenotypes
10.1111/j.1574-6968.1998.tb13202.x · 1998 · External reference
Deamidation and isoaspartate formation in smeared tau in paired helical filaments: unusual properties of the microtubule-binding domain of Tao
10.1074/jbc.274.11.7368 · 1999 · External reference
Detection and characterization of a protein isoaspartyl methyltransferase which becomes trapped in the extracellular space during blood vessel injury
10.1023/a:1026300924908 · 1997 · External reference
Injury-induced enzymatic methylation of aging collagen in the extracellular matrix of blood vessels
10.1023/a:1026352908978 · 1997 · External reference
Measurement of altered aspartyl residues in the scrapie associated form of prion protein
10.1006/bbrc.1998.8672 · 1998 · External reference
Deficiency in protein l-isoaspartyl methyltransferase results in a fatal progressive epilepsy
10.1523/jneurosci.18-06-02063.1998 · 1998 · External reference
Structural integrity of histone H2B in vivo requires the activity of protein l-isoaspartate O-methyltransferase, a putative protein repair enzyme
10.1074/jbc.m106682200 · 2001 · External reference